APAF1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description apoptotic peptidase activating factor 1|This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 317)
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Genes

428 genes differentially expressed following the APAF1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
CLEC4G C-type lectin domain family 4, member G 4.59301
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound 4.59301
TACSTD2 tumor-associated calcium signal transducer 2 4.59301
CDHR4 cadherin-related family member 4 4.59301
F5 coagulation factor V (proaccelerin, labile factor) 4.59301
LGR6 leucine-rich repeat containing G protein-coupled receptor 6 4.59301
SST somatostatin 4.59301
SYCE3 synaptonemal complex central element protein 3 4.59301
PRRX1 paired related homeobox 1 4.59301
AMER2 APC membrane recruitment protein 2 4.59301
PARP10 poly (ADP-ribose) polymerase family, member 10 4.59301
GLRA3 glycine receptor, alpha 3 4.59301
XKRX XK, Kell blood group complex subunit-related, X-linked 4.59301
F2RL2 coagulation factor II (thrombin) receptor-like 2 4.59301
POTEI POTE ankyrin domain family, member I 4.59301
MSX2 msh homeobox 2 4.59301
CCDC81 coiled-coil domain containing 81 4.59301
DND1 DND microRNA-mediated repression inhibitor 1 4.59301
DUOXA1 dual oxidase maturation factor 1 4.59301
GDF6 growth differentiation factor 6 4.59301
TTC29 tetratricopeptide repeat domain 29 4.59301
POF1B premature ovarian failure, 1B 4.59301
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6 4.59301
RTBDN retbindin 4.59301
CSMD3 CUB and Sushi multiple domains 3 4.59301
ANXA1 annexin A1 4.59301
TRIM15 tripartite motif containing 15 4.57162
TUBB8 tubulin, beta 8 class VIII 4.57162
PGAM4 phosphoglycerate mutase family member 4 4.57162
SCGB3A1 secretoglobin, family 3A, member 1 4.57162
SLC46A2 solute carrier family 46, member 2 4.57162
ASB18 ankyrin repeat and SOCS box containing 18 4.57162
PAX6 paired box 6 4.57162
ZEB2 zinc finger E-box binding homeobox 2 4.57162
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 4.57162
TGFB3 transforming growth factor, beta 3 4.57162
MTTP microsomal triglyceride transfer protein 4.57162
ASPA aspartoacylase 4.57162
GDNF glial cell derived neurotrophic factor 4.57162
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 4.57162
LYNX1 Ly6/neurotoxin 1 4.57162
TRIM72 tripartite motif containing 72, E3 ubiquitin protein ligase 4.57162
SFTPB surfactant protein B 4.57162
SPACA3 sperm acrosome associated 3 4.57162
MAS1 MAS1 proto-oncogene, G protein-coupled receptor 4.57162
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 4.57162
NWD1 NACHT and WD repeat domain containing 1 4.57162
EMCN endomucin 4.57162
ACRBP acrosin binding protein 4.57162
PCDHGA11 protocadherin gamma subfamily A, 11 4.57162
BTBD16 BTB (POZ) domain containing 16 4.57162
FAM81B family with sequence similarity 81, member B 4.57162
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 4.57162
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) 4.57162
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 4.57162
C2ORF80 chromosome 2 open reading frame 80 4.57162
OR2AJ1 olfactory receptor, family 2, subfamily AJ, member 1 4.57162
KIAA2012 KIAA2012 4.57162
SMIM5 small integral membrane protein 5 4.57162
TTLL8 tubulin tyrosine ligase-like family member 8 4.57162
SOWAHB sosondowah ankyrin repeat domain family member B 4.57162
LRTM3 leucine rich repeat transmembrane protein 3 4.57162
TREML1 triggering receptor expressed on myeloid cells-like 1 4.57162
OXT oxytocin/neurophysin I prepropeptide 4.57162
MMP20 matrix metallopeptidase 20 4.57162
TWIST1 twist family bHLH transcription factor 1 4.57162
EPCIP exosomal polycystin 1 interacting protein 4.57162
AVPR1B arginine vasopressin receptor 1B 4.57162
FIMP1 fertilization-influencing membrane protein 1 4.57162
C9ORF43 chromosome 9 open reading frame 43 4.57162
ASB2 ankyrin repeat and SOCS box containing 2 4.57162
SPATA22 spermatogenesis associated 22 4.57162
MROH5 maestro heat-like repeat family member 5 4.57162
LTA lymphotoxin alpha 4.57162
BEST1 bestrophin 1 4.57162
NPIPB8 nuclear pore complex interacting protein family, member B8 4.57162
DRC5 dynein regulatory complex subunit 5 4.57162
SAPCD1 suppressor APC domain containing 1 4.57162
PHF24 PHD finger protein 24 4.57162
H3-5 H3.5 histone 4.57162
SPEGNB SPEG neighbor 4.57162
CFAP97D2 CFAP97 domain containing 2 4.57162
CTXND1 cortexin domain containing 1 4.57162
H4C14 H4 clustered histone 14 4.57162
TMEM225B transmembrane protein 225B 4.57162
GARIN6 golgi associated RAB2 interactor family member 6 4.57162
CATSPERZ catsper channel auxiliary subunit zeta 4.57162
FLACC1 flagellum associated containing coiled-coil domains 1 4.57162
ANKRD40CL ANKRD40 C-terminal like 4.57162
TBXT T-box transcription factor T 4.57162
PGLYRP2 peptidoglycan recognition protein 2 4.57162
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 4.57162
GJD2 gap junction protein, delta 2, 36kDa 4.57162
FAM90A26 family with sequence similarity 90, member A26, pseudogene 4.57162
IL4I1 interleukin 4 induced 1 4.57162
LRRD1 leucine-rich repeats and death domain containing 1 4.57162
PARP3 poly (ADP-ribose) polymerase family, member 3 4.57162
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 4.57162
CDH5 cadherin 5, type 2 (vascular endothelium) 4.57162
WDR87 WD repeat domain 87 4.57162
MS4A4E membrane-spanning 4-domains, subfamily A, member 4E 4.57162
GPR52 G protein-coupled receptor 52 4.57162
RXFP1 relaxin/insulin-like family peptide receptor 1 4.57162
GPR75 G protein-coupled receptor 75 4.57162
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z 4.57162
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 4.57162
PDE1B phosphodiesterase 1B, calmodulin-dependent 4.57162
IL6 interleukin 6 4.57162
HAPLN2 hyaluronan and proteoglycan link protein 2 4.57162
CXCL16 chemokine (C-X-C motif) ligand 16 4.57162
CD79A CD79a molecule, immunoglobulin-associated alpha 4.57162
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2 4.57162
TEX101 testis expressed 101 4.57162
PRB1 proline-rich protein BstNI subfamily 1 4.57162
FAM3B family with sequence similarity 3, member B 4.57162
SYCP2 synaptonemal complex protein 2 4.57162
SDR9C7 short chain dehydrogenase/reductase family 9C, member 7 4.57162
FAM209B family with sequence similarity 209, member B 4.57162
MRLN myoregulin 4.57162
CLIC5 chloride intracellular channel 5 4.57162
ALPK1 alpha-kinase 1 4.57162
CTF1 cardiotrophin 1 4.57162
ZNF366 zinc finger protein 366 4.57162
FOXP2 forkhead box P2 4.57162
SLC25A52 solute carrier family 25, member 52 4.57162
ATP10B ATPase, class V, type 10B 4.57162
SLC47A2 solute carrier family 47 (multidrug and toxin extrusion), member 2 4.57162
ANKRD62 ankyrin repeat domain 62 4.57162
PGR progesterone receptor 4.57162
ANKRD37 ankyrin repeat domain 37 4.57162
ACKR3 atypical chemokine receptor 3 4.57162
NUTM2B NUT family member 2B 4.57162
MOBP myelin-associated oligodendrocyte basic protein 4.57162
GNG8 guanine nucleotide binding protein (G protein), gamma 8 4.57162
LGALS12 lectin, galactoside-binding, soluble, 12 4.57162
LCT lactase 4.57162
DQX1 DEAQ box RNA-dependent ATPase 1 4.57162
KCTD21 potassium channel tetramerization domain containing 21 4.57162
C2CD4D C2 calcium-dependent domain containing 4D 4.57162
TRIM55 tripartite motif containing 55 4.57162
TMEM139 transmembrane protein 139 4.57162
NUPR1 nuclear protein, transcriptional regulator, 1 4.57162
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa 4.57162
CPA5 carboxypeptidase A5 4.57162
AGXT2 alanine--glyoxylate aminotransferase 2 4.57162
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 4.57162
CALHM3 calcium homeostasis modulator 3 4.57162
DNTT DNA nucleotidylexotransferase 4.57162
WFDC6 WAP four-disulfide core domain 6 4.57162
COL6A5 collagen, type VI, alpha 5 4.57162
ARR3 arrestin 3, retinal (X-arrestin) 4.57162
LRRC19 leucine rich repeat containing 19 4.57162
SLCO2B1 solute carrier organic anion transporter family, member 2B1 4.57162
GRK1 G protein-coupled receptor kinase 1 4.57162
PXT1 peroxisomal, testis specific 1 4.57162
GPRC6A G protein-coupled receptor, class C, group 6, member A 4.57162
ITPKA inositol-trisphosphate 3-kinase A 4.57162
GALNTL5 polypeptide N-acetylgalactosaminyltransferase-like 5 4.57162
TAS2R46 taste receptor, type 2, member 46 4.57162
TRPM5 transient receptor potential cation channel, subfamily M, member 5 4.57162
PPY pancreatic polypeptide 4.57162
CCDC175 coiled-coil domain containing 175 4.57162
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4 4.57162
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 4.57162
LANCL3 LanC lantibiotic synthetase component C-like 3 (bacterial) 4.57162
LRRC31 leucine rich repeat containing 31 4.57162
HLA-G major histocompatibility complex, class I, G 4.57162
STRC stereocilin 4.57162
HEPN1 hepatocellular carcinoma, down-regulated 1 4.57162
LIF leukemia inhibitory factor 4.57162
SKOR1 SKI family transcriptional corepressor 1 4.57162
ZC3H11B zinc finger CCCH-type containing 11B pseudogene 4.57162
LRRC74A leucine rich repeat containing 74A 4.57162
GPR150 G protein-coupled receptor 150 4.57162
PATE1 prostate and testis expressed 1 4.57162
SNTN sentan, cilia apical structure protein 4.57162
HOXB2 homeobox B2 4.57162
FAIM2 Fas apoptotic inhibitory molecule 2 4.57162
EFCAB12 EF-hand calcium binding domain 12 4.57162
OR56B1 olfactory receptor, family 56, subfamily B, member 1 4.57162
C1ORF74 chromosome 1 open reading frame 74 4.54798
PCDHB4 protocadherin beta 4 4.54798
CLDN3 claudin 3 4.08033
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 4.00853
RPS8 ribosomal protein S8 3.81806
CARMIL2 capping protein regulator and myosin 1 linker 2 3.51093
NOD2 nucleotide-binding oligomerization domain containing 2 3.51093
NPIPA5 nuclear pore complex interacting protein family, member A5 3.51093
TAMALIN trafficking regulator and scaffold protein tamalin 3.51093
SOCS4 suppressor of cytokine signaling 4 3.42785
SV2B synaptic vesicle glycoprotein 2B 3.34965
XPO7 exportin 7 3.3192
PIH1D1 PIH1 domain containing 1 3.28396
CLU clusterin 3.25939
FERMT3 fermitin family member 3 3.11376
MMP24OS MMP24 opposite strand 3.10968
MST1 macrophage stimulating 1 3.07039
C16ORF96 chromosome 16 open reading frame 96 2.99166
SARS1 seryl-tRNA synthetase 1 2.99166
ZSCAN20 zinc finger and SCAN domain containing 20 2.99166
PROX1 prospero homeobox 1 2.99166
SPP1 secreted phosphoprotein 1 2.94689
C1QTNF7 C1q and tumor necrosis factor related protein 7 2.93822
RPL10 ribosomal protein L10 2.83001
AKNA AT-hook transcription factor 2.80585
TCF7 transcription factor 7 (T-cell specific, HMG-box) 2.7818
DDIT3 DNA-damage-inducible transcript 3 2.77955
ATL2 atlastin GTPase 2 2.73552
UPP1 uridine phosphorylase 1 2.65137
MAT2B methionine adenosyltransferase II, beta 2.64536
RNPEP arginyl aminopeptidase (aminopeptidase B) 2.62905
KIAA0825 KIAA0825 2.61373
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.61373
WBP2 WW domain binding protein 2 2.6077
MAP3K12 mitogen-activated protein kinase kinase kinase 12 2.57564
ADRM1 adhesion regulating molecule 1 2.53059
FBXO16 F-box protein 16 2.51524
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 2.49865
GDF15 growth differentiation factor 15 2.48076
CPNE5 copine V 2.479
DPY19L1 dpy-19-like 1 (C. elegans) 2.42109
ZNF175 zinc finger protein 175 2.42031
HMOX1 heme oxygenase 1 2.41725
RPS9 ribosomal protein S9 2.4056
TMEM64 transmembrane protein 64 2.38766
POMGNT2 protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) 2.37584
OPN1SW opsin 1 (cone pigments), short-wave-sensitive 2.35488
MAB21L4 mab-21 like 4 2.35488
RPS27L ribosomal protein S27-like 2.33416
ERI3 ERI1 exoribonuclease family member 3 2.30899
RPS19 ribosomal protein S19 2.3003
FTL ferritin, light polypeptide 2.2733
ZNF584 zinc finger protein 584 2.26418
ASCC3 activating signal cointegrator 1 complex subunit 3 2.26254
PIP4P2 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2 2.25653
FAM81A family with sequence similarity 81, member A 2.23737
FIRRM FIGNL1 interacting regulator of recombination and mitosis 2.22077
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 2.22077
WIPI2 WD repeat domain, phosphoinositide interacting 2 2.21711
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 2.2151
SENP7 SUMO1/sentrin specific peptidase 7 2.2151
SIRT7 sirtuin 7 2.2151
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 2.21412
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 2.18215
LUC7L LUC7-like (S. cerevisiae) 2.17931
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 2.1601
LEFTY1 left-right determination factor 1 2.15746
NFE2L1 nuclear factor, erythroid 2-like 1 2.15069
C18ORF54 chromosome 18 open reading frame 54 2.15046
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 2.15046
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) 2.13625
GPR141 G protein-coupled receptor 141 2.13625
NSUN6 NOP2/Sun domain family, member 6 2.1133
ATF5 activating transcription factor 5 2.1133
PTDSS2 phosphatidylserine synthase 2 2.10388
MSRB1 methionine sulfoxide reductase B1 2.10344
CCDC50 coiled-coil domain containing 50 2.10149
S100A10 S100 calcium binding protein A10 2.098
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 2.09085
ATAD3C ATPase family, AAA domain containing 3C 2.09085
DESI2 desumoylating isopeptidase 2 2.09085
TMX2 thioredoxin-related transmembrane protein 2 2.08196
DBNDD2 dysbindin (dystrobrevin binding protein 1) domain containing 2 2.07356
WDR6 WD repeat domain 6 2.07356
BBS9 Bardet-Biedl syndrome 9 2.0688
UBE3D ubiquitin protein ligase E3D 2.0688
PCNP PEST proteolytic signal containing nuclear protein 2.06388
RPS28 ribosomal protein S28 2.05527
AKAP8L A kinase (PRKA) anchor protein 8-like 2.05527
NUDT22 nudix (nucleoside diphosphate linked moiety X)-type motif 22 2.0513
HDX highly divergent homeobox 2.0513
TRIM59 tripartite motif containing 59 2.04539
DTNA dystrobrevin, alpha 2.0452
IDO1 indoleamine 2,3-dioxygenase 1 2.04355
NBPF1 neuroblastoma breakpoint family, member 1 2.04304
RAB2A RAB2A, member RAS oncogene family 2.04299
RAB4A RAB4A, member RAS oncogene family 2.04299
FTH1 ferritin, heavy polypeptide 1 2.02641
RPS3 ribosomal protein S3 2.02318
CDH8 cadherin 8, type 2 2.02318
PTRHD1 peptidyl-tRNA hydrolase domain containing 1 2.02318
NQO2 NAD(P)H dehydrogenase, quinone 2 2.01418
EIF1 eukaryotic translation initiation factor 1 2.01418
CDC42 cell division cycle 42 2.00687

decreased expression

Symbol Name Standardized Value
CCKBR cholecystokinin B receptor -4.59301
KREMEN2 kringle containing transmembrane protein 2 -4.59301
FLNC filamin C, gamma -4.59301
KIAA0319 KIAA0319 -4.59301
H4C13 H4 clustered histone 13 -4.59301
GDPGP1 GDP-D-glucose phosphorylase 1 -4.59301
NPR1 natriuretic peptide receptor 1 -4.59301
L1CAM L1 cell adhesion molecule -4.57162
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 -4.57162
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon -4.57162
FAM229A family with sequence similarity 229, member A -4.56557
GPR37L1 G protein-coupled receptor 37 like 1 -4.56557
C1ORF116 chromosome 1 open reading frame 116 -4.56557
VSTM2L V-set and transmembrane domain containing 2 like -4.56557
SMIM47 small integral membrane protein 47 -4.56557
GNRHR gonadotropin-releasing hormone receptor -4.56557
BRICD5 BRICHOS domain containing 5 -4.56557
CLCN1 chloride channel, voltage-sensitive 1 -4.56557
SHBG sex hormone-binding globulin -4.56557
GREM2 gremlin 2, DAN family BMP antagonist -4.56557
C17ORF100 chromosome 17 open reading frame 100 -4.56557
OR2H2 olfactory receptor, family 2, subfamily H, member 2 -4.56557
ASCL1 achaete-scute family bHLH transcription factor 1 -4.56557
CD200R1L CD200 receptor 1-like -4.56557
RAB9B RAB9B, member RAS oncogene family -4.56557
SYT15B synaptotagmin 15B -4.56557
DNAI7 dynein axonemal intermediate chain 7 -4.56557
STYXL2 serine/threonine/tyrosine interacting like 2 -4.56557
NHLH2 nescient helix loop helix 2 -4.56557
C2ORF72 chromosome 2 open reading frame 72 -4.56557
MUSTN1 musculoskeletal, embryonic nuclear protein 1 -4.56557
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G -4.56557
TFF3 trefoil factor 3 (intestinal) -4.56557
CDKL2 cyclin-dependent kinase-like 2 (CDC2-related kinase) -4.56557
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 -4.56557
AMBP alpha-1-microglobulin/bikunin precursor -4.56557
TSGA10IP testis specific, 10 interacting protein -4.56557
TAS2R30 taste receptor, type 2, member 30 -4.56557
NECAB2 N-terminal EF-hand calcium binding protein 2 -4.56557
CD8B CD8b molecule -4.56557
EXD1 exonuclease 3'-5' domain containing 1 -4.56557
AMIGO1 adhesion molecule with Ig-like domain 1 -4.56557
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -4.56557
ANKRD61 ankyrin repeat domain 61 -4.56557
RAB27B RAB27B, member RAS oncogene family -4.56557
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B -4.56557
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -4.56557
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -4.47906
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2 -4.45024
NPIPB2 nuclear pore complex interacting protein family member B2 -4.45024
PFN1 profilin 1 -3.76226
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit -3.56386
SNRPF small nuclear ribonucleoprotein polypeptide F -3.52896
ZNF888 zinc finger protein 888 -3.5231
IQCH IQ motif containing H -3.46888
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 -3.46888
SPINK8 serine peptidase inhibitor, Kazal type 8 (putative) -3.43238
ZCCHC3 zinc finger, CCHC domain containing 3 -3.42567
RNGTT RNA guanylyltransferase and 5'-phosphatase -3.3511
DCHS1 dachsous cadherin-related 1 -3.34483
COL6A6 collagen, type VI, alpha 6 -3.34483
ZNF540 zinc finger protein 540 -3.34483
RHPN1 rhophilin, Rho GTPase binding protein 1 -3.34483
STK33 serine/threonine kinase 33 -3.15336
GAN gigaxonin -3.13256
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta -3.11739
GTF2A1 general transcription factor IIA, 1, 19/37kDa -3.11436
ACVR1B activin A receptor, type IB -3.05715
GPSM3 G-protein signaling modulator 3 -3.03268
TMEM200B transmembrane protein 200B -3.03268
TMEM14B transmembrane protein 14B -2.97102
GOLGA3 golgin A3 -2.88935
RMDN1 regulator of microtubule dynamics 1 -2.86381
SDF4 stromal cell derived factor 4 -2.83166
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -2.83001
MRPL20 mitochondrial ribosomal protein L20 -2.79865
CNBP CCHC-type zinc finger, nucleic acid binding protein -2.78526
SYT13 synaptotagmin XIII -2.76275
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 -2.73552
GTSE1 G-2 and S-phase expressed 1 -2.71463
VRK1 vaccinia related kinase 1 -2.53728
PTPRJ protein tyrosine phosphatase, receptor type, J -2.50439
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa -2.46108
ENG endoglin -2.42922
VSNL1 visinin-like 1 -2.42031
THAP7 THAP domain containing 7 -2.41725
USP33 ubiquitin specific peptidase 33 -2.41422
JPT2 Jupiter microtubule associated homolog 2 -2.41422
TP53I11 tumor protein p53 inducible protein 11 -2.36233
SPDYE17 speedy/RINGO cell cycle regulator family member E17 -2.33416
PYY peptide YY -2.33416
CRTC2 CREB regulated transcription coactivator 2 -2.33416
COL5A3 collagen, type V, alpha 3 -2.33416
CEP135 centrosomal protein 135kDa -2.33416
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled -2.33416
ARMC6 armadillo repeat containing 6 -2.33416
RDH10 retinol dehydrogenase 10 (all-trans) -2.33416
ESRRB estrogen-related receptor beta -2.33416
NR4A2 nuclear receptor subfamily 4, group A, member 2 -2.33416
CHD8 chromodomain helicase DNA binding protein 8 -2.32954
SCML2 sex comb on midleg-like 2 (Drosophila) -2.30899
CRPPA CDP-L-ribitol pyrophosphorylase A -2.3073
FGFR4 fibroblast growth factor receptor 4 -2.3035
TUBA8 tubulin, alpha 8 -2.292
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.292
KLK1 kallikrein 1 -2.292
EME1 essential meiotic structure-specific endonuclease 1 -2.2822
DLD dihydrolipoamide dehydrogenase -2.26498
ILF3 interleukin enhancer binding factor 3, 90kDa -2.24865
COMMD1 copper metabolism (Murr1) domain containing 1 -2.24754
PRRT3 proline-rich transmembrane protein 3 -2.23695
GATAD2A GATA zinc finger domain containing 2A -2.22511
CRACR2A calcium release activated channel regulator 2A -2.21996
MICOS10 mitochondrial contact site and cristae organizing system subunit 10 -2.2151
COL24A1 collagen, type XXIV, alpha 1 -2.19455
ZNF439 zinc finger protein 439 -2.19093
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 -2.16531
PHF2 PHD finger protein 2 -2.15291
THAP11 THAP domain containing 11 -2.15069
BRSK2 BR serine/threonine kinase 2 -2.15046
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 -2.14232
MAP7D3 MAP7 domain containing 3 -2.13878
LRRC34 leucine rich repeat containing 34 -2.11743
SRRD SRR1 domain containing -2.11356
APEH acylaminoacyl-peptide hydrolase -2.10703
IKBIP IKBKB interacting protein -2.08526
NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) -2.08329
HMGB1 high mobility group box 1 -2.08264
GPD1L glycerol-3-phosphate dehydrogenase 1-like -2.0688
SRGAP2B SLIT-ROBO Rho GTPase activating protein 2B -2.0688
SLIT2 slit homolog 2 (Drosophila) -2.06388
C16ORF89 chromosome 16 open reading frame 89 -2.05527
SYT1 synaptotagmin I -2.0513
FAM53C family with sequence similarity 53, member C -2.04299
SUB1 SUB1 homolog (S. cerevisiae) -2.04299
ZDHHC8 zinc finger, DHHC-type containing 8 -2.04087
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha -2.03096
MINPP1 multiple inositol-polyphosphate phosphatase 1 -2.02549
ADAM22 ADAM metallopeptidase domain 22 -2.02318
INA internexin neuronal intermediate filament protein, alpha -2.01418
RP9 retinitis pigmentosa 9 (autosomal dominant) -2.01212
CC2D1B coiled-coil and C2 domain containing 1B -2.01212
ZNF124 zinc finger protein 124 -2.01212
PRELID2 PRELI domain containing 2 -2.01102