| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | adenomatosis polyposis coli down-regulated 1|This locus encodes an inhibitor of the Wnt signaling pathway. Mutations at this locus have been associated with hereditary hypotrichosis simplex. Increased expression of this gene may also be associated with colorectal carcinogenesis.[provided by RefSeq, Sep 2010] (NCBI Entrez Gene Database, 147495) |
| External Link | https://ncbi.nlm.nih.gov/gene/147495 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the APCDD1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT19 | keratin 19, type I | 0.0139922 |
| CSTA | cystatin A (stefin A) | 0.013147 |
| E2F2 | E2F transcription factor 2 | 0.0126437 |
| S100P | S100 calcium binding protein P | 0.0124586 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.0123636 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.0117154 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.0116177 |
| MAL | mal, T-cell differentiation protein | 0.0113434 |
| KRT13 | keratin 13, type I | 0.0109713 |
| ETNK1 | ethanolamine kinase 1 | 0.0108838 |
| SCEL | sciellin | 0.010539 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0105048 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.010464 |
| MSLN | mesothelin | 0.0104604 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0103571 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.0103552 |
| VCAN | versican | 0.0102412 |
| TSPAN13 | tetraspanin 13 | 0.0101497 |
| DEFB1 | defensin, beta 1 | 0.0100335 |
| AMDHD2 | amidohydrolase domain containing 2 | 0.00984268 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00982008 |
| NPY1R | neuropeptide Y receptor Y1 | 0.00981143 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | 0.00977739 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 0.00969775 |
| GPX1 | glutathione peroxidase 1 | 0.00969419 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.00966357 |
| HBB | hemoglobin, beta | 0.00959021 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | 0.00954724 |
| SPRR3 | small proline-rich protein 3 | 0.00945651 |
| TGM2 | transglutaminase 2 | 0.00945381 |
| TMEM100 | transmembrane protein 100 | 0.00930542 |
| WASF1 | WAS protein family, member 1 | 0.00923918 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.00921919 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00921439 |
| PENK | proenkephalin | 0.00907 |
| KRT7 | keratin 7, type II | 0.0090143 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.00893746 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00886297 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.00869872 |
| CALB1 | calbindin 1, 28kDa | 0.00868942 |
| MT1E | metallothionein 1E | 0.00868933 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | 0.00849145 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.00833935 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00833592 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00830272 |
| HOXC6 | homeobox C6 | 0.00829006 |
| MYBPC1 | myosin binding protein C, slow type | 0.0082467 |
| RHCG | Rh family, C glycoprotein | 0.00823198 |
| CLIC3 | chloride intracellular channel 3 | 0.00822424 |
| HIST3H2A | histone cluster 3, H2a | 0.00820849 |
| HOPX | HOP homeobox | 0.00817182 |
| ADIRF | adipogenesis regulatory factor | 0.00812913 |
| DCK | deoxycytidine kinase | 0.00811441 |
| MSMB | microseminoprotein, beta- | 0.00807757 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00804177 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00796482 |
| TSPAN1 | tetraspanin 1 | 0.00796222 |
| EMX2 | empty spiracles homeobox 2 | 0.00793278 |
| SELENOT | selenoprotein T | 0.0078401 |
| GPX7 | glutathione peroxidase 7 | 0.00782972 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0077679 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.00774221 |
| EPCAM | epithelial cell adhesion molecule | 0.00769614 |
| SYT1 | synaptotagmin I | 0.00768756 |
| MUC16 | mucin 16, cell surface associated | 0.00763889 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.00761779 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.00760611 |
| KLK6 | kallikrein-related peptidase 6 | 0.00758736 |
| CLDN10 | claudin 10 | 0.00758384 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.00757059 |
| C6ORF48 | chromosome 6 open reading frame 48 | 0.00756139 |
| VPREB1 | pre-B lymphocyte 1 | 0.00755735 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00752232 |
| LY6D | lymphocyte antigen 6 complex, locus D | 0.00750431 |
| UPK1B | uroplakin 1B | 0.0074985 |
| SOX17 | SRY (sex determining region Y)-box 17 | 0.00728372 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.0072632 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.00725323 |
| MYRF | myelin regulatory factor | 0.00724298 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.00722396 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00718884 |
| PDZK1 | PDZ domain containing 1 | 0.0071787 |
| RPS26 | ribosomal protein S26 | 0.00715416 |
| EMP2 | epithelial membrane protein 2 | 0.00714453 |
| TMEM110 | transmembrane protein 110 | 0.0070341 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00702869 |
| BPGM | 2,3-bisphosphoglycerate mutase | 0.00702487 |
| TNNC1 | troponin C type 1 (slow) | 0.00698848 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.00694558 |
| TSPAN8 | tetraspanin 8 | 0.00693037 |
| MT1G | metallothionein 1G | 0.00691585 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 0.00690994 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00684122 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.00683027 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.00680031 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0067913 |
| CCK | cholecystokinin | 0.00676377 |
| REEP5 | receptor accessory protein 5 | 0.00673588 |
| NME5 | NME/NM23 family member 5 | 0.00671205 |
| SMPX | small muscle protein, X-linked | 0.00668003 |
| FBXO11 | F-box protein 11 | 0.00667451 |
| MMP10 | matrix metallopeptidase 10 | 0.00666643 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00666563 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.00663201 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.00661291 |
| MT1M | metallothionein 1M | 0.00656876 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa | 0.00655308 |
| LYPD1 | LY6/PLAUR domain containing 1 | 0.00654794 |
| GDE1 | glycerophosphodiester phosphodiesterase 1 | 0.0065107 |
| EHD3 | EH-domain containing 3 | 0.00649911 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0064647 |
| CLDN1 | claudin 1 | 0.00646075 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.00644312 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.00642795 |
| MT1X | metallothionein 1X | 0.00642387 |
| B3GALNT1 | beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) | 0.00641744 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa | 0.00641094 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00640861 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.0063983 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | 0.00639405 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.00636149 |
| PPM1A | protein phosphatase, Mg2+/Mn2+ dependent, 1A | 0.00634853 |
| SORD | sorbitol dehydrogenase | 0.00632262 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00632154 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00630551 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.00629292 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.00627972 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.00627638 |
| MYOT | myotilin | 0.00626526 |
| RBM34 | RNA binding motif protein 34 | 0.00626483 |
| CRIP2 | cysteine-rich protein 2 | 0.00625789 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | 0.00624266 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.006242 |
| MLF1 | myeloid leukemia factor 1 | 0.00622173 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.00622096 |
| PFDN5 | prefoldin subunit 5 | 0.00621638 |
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 | 0.00620887 |
| F5 | coagulation factor V (proaccelerin, labile factor) | 0.00619495 |
| CRNN | cornulin | 0.00619487 |
| TMPRSS11E | transmembrane protease, serine 11E | 0.00616344 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.00615506 |
| CYB5A | cytochrome b5 type A (microsomal) | 0.00610333 |
| CTTN | cortactin | 0.00608033 |
| COMT | catechol-O-methyltransferase | 0.00605393 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.00602737 |
| BTG2 | BTG family, member 2 | 0.00602565 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 0.00602323 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 | 0.00601939 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | 0.00599144 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00598798 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | 0.00598539 |
| BCL2L1 | BCL2-like 1 | 0.00598432 |
| NTS | neurotensin | 0.0059824 |
| ATP6V1G1 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 | 0.00597142 |
| BID | BH3 interacting domain death agonist | 0.00595658 |
| PRKCH | protein kinase C, eta | 0.00595328 |
| TPM3 | tropomyosin 3 | 0.00595274 |
| RPL36AL | ribosomal protein L36a-like | 0.00593596 |
| VLDLR | very low density lipoprotein receptor | 0.00593137 |
| MAGEA4 | melanoma antigen family A4 | 0.00591408 |
| SIAH2 | siah E3 ubiquitin protein ligase 2 | 0.00591252 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00590107 |
| BPIFA1 | BPI fold containing family A, member 1 | 0.00589606 |
| CHRDL1 | chordin-like 1 | 0.00589599 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | 0.00589221 |
| CSTB | cystatin B (stefin B) | 0.00585544 |
| LOC105375355 | uroplakin-3b | 0.00585029 |
| MAGEA3 | melanoma antigen family A3 | 0.00582929 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00582049 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent | 0.00580715 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.00580383 |
| TRAM1 | translocation associated membrane protein 1 | 0.00580198 |
| MT1F | metallothionein 1F | 0.0057823 |
| GNLY | granulysin | 0.00577665 |
| RER1 | retention in endoplasmic reticulum sorting receptor 1 | 0.00577579 |
| SPON2 | spondin 2, extracellular matrix protein | 0.00577563 |
| CXCR2 | chemokine (C-X-C motif) receptor 2 | 0.00575338 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00574706 |
| AHNAK | AHNAK nucleoprotein | 0.00574158 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.005738 |
| MAGEB2 | melanoma antigen family B2 | 0.00573166 |
| LY86 | lymphocyte antigen 86 | 0.00571635 |
| CD81 | CD81 molecule | 0.00571049 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.00570673 |
| CCR2 | chemokine (C-C motif) receptor 2 | 0.00570519 |
| CRIPT | cysteine-rich PDZ-binding protein | 0.00570304 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | 0.00569705 |
| CDC42SE1 | CDC42 small effector 1 | 0.00569064 |
| TMEM135 | transmembrane protein 135 | 0.00567254 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.0056673 |
| PSAP | prosaposin | 0.00566315 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.00566236 |
| KLRC3 | killer cell lectin-like receptor subfamily C, member 3 | 0.00565753 |
| CFH | complement factor H | 0.00564086 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00562547 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | 0.00562044 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.00561731 |
| ZNF277 | zinc finger protein 277 | 0.00561714 |
| LINC00623 | long intergenic non-protein coding RNA 623 | 0.00560962 |
| DNALI1 | dynein, axonemal, light intermediate chain 1 | 0.00559174 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 | 0.00558413 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | 0.00557236 |
| MMP1 | matrix metallopeptidase 1 | 0.00557145 |
| MYL6B | myosin, light chain 6B, alkali, smooth muscle and non-muscle | 0.0055561 |
| HIKESHI | heat shock protein nuclear import factor hikeshi | 0.00555548 |
| GYPC | glycophorin C (Gerbich blood group) | 0.00553516 |
| KRT18 | keratin 18, type I | 0.00553042 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | 0.00552897 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 0.00552296 |
| DCTN3 | dynactin 3 (p22) | 0.00552072 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.00551718 |
| TSLIG2 | tRNA splicing ligase complex subunit 2 | 0.00550973 |
| SLC12A1 | solute carrier family 12 (sodium/potassium/chloride transporter), member 1 | 0.00550177 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0054918 |
| CALHM2 | calcium homeostasis modulator 2 | 0.00548842 |
| NEK7 | NIMA-related kinase 7 | 0.00548752 |
| FOSL2 | FOS-like antigen 2 | 0.00547737 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.00547025 |
| ACTN2 | actinin, alpha 2 | 0.00546933 |
| TPM2 | tropomyosin 2 (beta) | 0.00546014 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 0.00544887 |
| TTN | titin | 0.00544843 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0054419 |
| DAZAP2 | DAZ associated protein 2 | 0.00541756 |
| MEG3 | maternally expressed 3 (non-protein coding) | 0.00539723 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 0.00538584 |
| LIPT1 | lipoyltransferase 1 | 0.00538407 |
| S100A12 | S100 calcium binding protein A12 | 0.00536901 |
| GUCY2C | guanylate cyclase 2C | 0.00536394 |
| KLHL41 | kelch-like family member 41 | 0.00535153 |
| LDB2 | LIM domain binding 2 | 0.0053511 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | 0.00534932 |
| CALCRL | calcitonin receptor-like | 0.00534862 |
| BUD31 | BUD31 homolog (S. cerevisiae) | 0.0053428 |
| DYNC2LI1 | dynein, cytoplasmic 2, light intermediate chain 1 | 0.00534084 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.00532925 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0053217 |
| RNF14 | ring finger protein 14 | 0.00531842 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.00531437 |
| HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled | 0.00530015 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.00529903 |
| MME | membrane metallo-endopeptidase | 0.00528937 |
| POLR2G | polymerase (RNA) II (DNA directed) polypeptide G | 0.00528388 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00527481 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.00527353 |
| ACYP2 | acylphosphatase 2, muscle type | 0.00527265 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00526612 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00526095 |
| OXSM | 3-oxoacyl-ACP synthase, mitochondrial | 0.00525787 |
| AGPS | alkylglycerone phosphate synthase | 0.00525345 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | -0.0193373 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.0167252 |
| FCGBP | Fc fragment of IgG binding protein | -0.0164453 |
| NAV2 | neuron navigator 2 | -0.0147716 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.0141977 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.0135229 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | -0.011701 |
| PEG10 | paternally expressed 10 | -0.011657 |
| OLFM4 | olfactomedin 4 | -0.0115365 |
| MMP9 | matrix metallopeptidase 9 | -0.0107738 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.0107572 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.0106449 |
| CLCA1 | chloride channel accessory 1 | -0.0102903 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0102411 |
| FABP1 | fatty acid binding protein 1, liver | -0.0101837 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0101481 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.00974158 |
| ACKR3 | atypical chemokine receptor 3 | -0.00971317 |
| GPA33 | glycoprotein A33 (transmembrane) | -0.00957761 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | -0.00948069 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.00939407 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.0093798 |
| EFNB2 | ephrin-B2 | -0.00922558 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.00919295 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00916598 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.00912227 |
| PLS3 | plastin 3 | -0.00904044 |
| SNAI2 | snail family zinc finger 2 | -0.0089952 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.00896752 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00880375 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00879986 |
| KRT20 | keratin 20, type I | -0.00860524 |
| AUTS2 | autism susceptibility candidate 2 | -0.00859147 |
| FST | follistatin | -0.00856248 |
| CGA | glycoprotein hormones, alpha polypeptide | -0.00853299 |
| ZG16 | zymogen granule protein 16 | -0.00850367 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00849964 |
| MTARC1 | mitochondrial amidoxime reducing component 1 | -0.00849022 |
| CPE | carboxypeptidase E | -0.00838459 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | -0.00837239 |
| MMP12 | matrix metallopeptidase 12 | -0.00835021 |
| WFDC1 | WAP four-disulfide core domain 1 | -0.00833784 |
| ZNF395 | zinc finger protein 395 | -0.00829629 |
| RGS16 | regulator of G-protein signaling 16 | -0.00827051 |
| NOX1 | NADPH oxidase 1 | -0.00824232 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.00811739 |
| HTRA1 | HtrA serine peptidase 1 | -0.00810349 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | -0.0080736 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00806207 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.00791991 |
| MEP1A | meprin A, alpha (PABA peptide hydrolase) | -0.00791807 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00785138 |
| PER3 | period circadian clock 3 | -0.0077993 |
| GUCA2A | guanylate cyclase activator 2A (guanylin) | -0.00772596 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00769955 |
| JAG1 | jagged 1 | -0.00766483 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 | -0.00766289 |
| GNAS | GNAS complex locus | -0.00761828 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.00757097 |
| NDRG1 | N-myc downstream regulated 1 | -0.00756901 |
| GAL | galanin/GMAP prepropeptide | -0.00752495 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00752069 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00750559 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.00750218 |
| SNX7 | sorting nexin 7 | -0.00742228 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0073958 |
| RTN1 | reticulon 1 | -0.00735124 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.00734994 |
| SPRY2 | sprouty homolog 2 (Drosophila) | -0.00730889 |
| NR1I2 | nuclear receptor subfamily 1, group I, member 2 | -0.00727872 |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 | -0.0072697 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.00722659 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | -0.00722467 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.0072112 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0071859 |
| COL6A1 | collagen, type VI, alpha 1 | -0.00715622 |
| RCAN2 | regulator of calcineurin 2 | -0.00713692 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | -0.00711902 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | -0.00711412 |
| TARDBP | TAR DNA binding protein | -0.0071139 |
| IL2RG | interleukin 2 receptor, gamma | -0.00711367 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | -0.0070693 |
| SDC3 | syndecan 3 | -0.00704015 |
| CHKB | choline kinase beta | -0.00702262 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | -0.00700034 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.00699345 |
| RBPMS | RNA binding protein with multiple splicing | -0.0069932 |
| TNC | tenascin C | -0.00697196 |
| TGFB1 | transforming growth factor, beta 1 | -0.00696462 |
| NXPE4 | neurexophilin and PC-esterase domain family, member 4 | -0.00693876 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.00685869 |
| FOXF1 | forkhead box F1 | -0.006738 |
| ASPH | aspartate beta-hydroxylase | -0.00668599 |
| OLFML2A | olfactomedin-like 2A | -0.00668183 |
| TXLNA | taxilin alpha | -0.00666756 |
| STEAP3 | STEAP family member 3, metalloreductase | -0.00665999 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -0.00665423 |
| PLXNC1 | plexin C1 | -0.00659751 |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | -0.00658256 |
| CADM1 | cell adhesion molecule 1 | -0.00654225 |
| FRZB | frizzled-related protein | -0.00652301 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00651468 |
| TUBA4A | tubulin, alpha 4a | -0.0065065 |
| IGSF3 | immunoglobulin superfamily, member 3 | -0.00649832 |
| ITGA8 | integrin, alpha 8 | -0.0064952 |
| PLXNA1 | plexin A1 | -0.00649368 |
| AQP8 | aquaporin 8 | -0.00648255 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | -0.00647437 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.00647228 |
| SVIL | supervillin | -0.00646885 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | -0.00643931 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00641125 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | -0.00639491 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00637776 |
| DCT | dopachrome tautomerase | -0.00636551 |
| PIGR | polymeric immunoglobulin receptor | -0.00635013 |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D | -0.00633596 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00632602 |
| SELENBP1 | selenium binding protein 1 | -0.006307 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | -0.00628109 |
| TTR | transthyretin | -0.00627177 |
| CALML3 | calmodulin-like 3 | -0.00627169 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00626694 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.00625619 |
| GCG | glucagon | -0.00625463 |
| TUBB2B | tubulin, beta 2B class IIb | -0.00624932 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | -0.00619936 |
| ATP10B | ATPase, class V, type 10B | -0.00619475 |
| CASD1 | CAS1 domain containing 1 | -0.00618612 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00618182 |
| C1QA | complement component 1, q subcomponent, A chain | -0.00616832 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00616713 |
| SYNM | synemin, intermediate filament protein | -0.00615772 |
| DGCR8 | DGCR8 microprocessor complex subunit | -0.0061576 |
| SOWAHC | sosondowah ankyrin repeat domain family member C | -0.00615035 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.00614364 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 | -0.00614048 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.00613501 |
| A2M | alpha-2-macroglobulin | -0.00610469 |
| LOXL2 | lysyl oxidase-like 2 | -0.00605695 |
| PIP | prolactin-induced protein | -0.00604921 |
| CHP2 | calcineurin-like EF-hand protein 2 | -0.00603918 |
| ENAH | enabled homolog (Drosophila) | -0.00602609 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.00602329 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.00602129 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00602038 |
| COL8A2 | collagen, type VIII, alpha 2 | -0.00601411 |
| HEPH | hephaestin | -0.0059982 |
| BTNL8 | butyrophilin-like 8 | -0.00599759 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 | -0.00596218 |
| GLS | glutaminase | -0.00594747 |
| EHD2 | EH-domain containing 2 | -0.00593986 |
| IPO9 | importin 9 | -0.00593327 |
| DUOX2 | dual oxidase 2 | -0.00591122 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic | -0.00590947 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00589586 |
| NRCAM | neuronal cell adhesion molecule | -0.00589368 |
| FERMT2 | fermitin family member 2 | -0.00588993 |
| GSDMB | gasdermin B | -0.00588827 |
| TOX | thymocyte selection-associated high mobility group box | -0.00585746 |
| DNASE1L3 | deoxyribonuclease I-like 3 | -0.00585417 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00585412 |
| HSPB1 | heat shock 27kDa protein 1 | -0.00583644 |
| LY75 | lymphocyte antigen 75 | -0.00581307 |
| DKFZP586I1420 | uncharacterized protein DKFZp586I1420 | -0.0058029 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | -0.00579343 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.00579042 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.00578538 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00577162 |
| ITGA6 | integrin, alpha 6 | -0.00576191 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | -0.00575833 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.00575674 |
| MXRA8 | matrix-remodelling associated 8 | -0.00575117 |
| FSTL1 | follistatin-like 1 | -0.00574656 |
| PMM2 | phosphomannomutase 2 | -0.00573463 |
| MEIS2 | Meis homeobox 2 | -0.0057344 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -0.00572894 |
| MFAP2 | microfibrillar-associated protein 2 | -0.00572424 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.0057227 |
| MCF2L | MCF.2 cell line derived transforming sequence-like | -0.0057172 |
| KDR | kinase insert domain receptor | -0.00571622 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00571578 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.00571527 |
| CD177 | CD177 molecule | -0.00569832 |
| COL9A2 | collagen, type IX, alpha 2 | -0.00566441 |
| CELP | carboxyl ester lipase pseudogene | -0.00565719 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) | -0.00565515 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00565355 |
| INSM1 | insulinoma-associated 1 | -0.00561902 |
| MUC13 | mucin 13, cell surface associated | -0.00561684 |
| L1CAM | L1 cell adhesion molecule | -0.00560292 |
| ACTN1 | actinin, alpha 1 | -0.0055601 |
| ISL1 | ISL LIM homeobox 1 | -0.0055492 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | -0.00554892 |
| NOTCH1 | notch 1 | -0.00554611 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -0.00553825 |
| CD4 | CD4 molecule | -0.00553562 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | -0.00553551 |
| TCF7 | transcription factor 7 (T-cell specific, HMG-box) | -0.0055232 |
| ADORA2B | adenosine A2b receptor | -0.00552305 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | -0.00552152 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.00551491 |
| ARHGAP17 | Rho GTPase activating protein 17 | -0.00549221 |
| GOLIM4 | golgi integral membrane protein 4 | -0.00548669 |
| ANGPTL2 | angiopoietin-like 2 | -0.00547953 |
| FAM189A2 | family with sequence similarity 189, member A2 | -0.00547793 |
| GEM | GTP binding protein overexpressed in skeletal muscle | -0.00547282 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.00546004 |
| TMEM164 | transmembrane protein 164 | -0.00545907 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.00545435 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00543372 |
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 | -0.00542238 |
| CNTNAP2 | contactin associated protein-like 2 | -0.00542121 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.00540594 |
| H2AX | H2A.X variant histone | -0.00539702 |
| PLVAP | plasmalemma vesicle associated protein | -0.00538452 |
| RRM1 | ribonucleotide reductase M1 | -0.00537897 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.00537876 |
| DIPK1A | divergent protein kinase domain 1A | -0.00537571 |
| PSMF1 | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | -0.00537211 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 | -0.00536856 |
| PLXND1 | plexin D1 | -0.00536529 |
| CTSD | cathepsin D | -0.00536439 |
| ANGPT1 | angiopoietin 1 | -0.00533829 |
| HNRNPH2 | heterogeneous nuclear ribonucleoprotein H2 (H') | -0.00533224 |
| KRT17 | keratin 17, type I | -0.00532194 |
| CA4 | carbonic anhydrase IV | -0.00530839 |
| FNBP1 | formin binding protein 1 | -0.00530346 |
| SLC46A3 | solute carrier family 46, member 3 | -0.00529808 |
| AKAP1 | A kinase (PRKA) anchor protein 1 | -0.00529328 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00529077 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | -0.00529059 |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 | -0.00528668 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00528557 |
| MYO1A | myosin IA | -0.00527626 |
| FKBP1A | FK506 binding protein 1A, 12kDa | -0.00526685 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) | -0.00526627 |
| KIF1B | kinesin family member 1B | -0.00526216 |
| PAX6 | paired box 6 | -0.00526049 |
| TOX3 | TOX high mobility group box family member 3 | -0.00525764 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -0.00525624 |
| SPATA20 | spermatogenesis associated 20 | -0.0052459 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.00524045 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | -0.00523736 |
| TRAF5 | TNF receptor-associated factor 5 | -0.00523435 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.00523048 |
| CEP70 | centrosomal protein 70kDa | -0.00521757 |
| PROM1 | prominin 1 | -0.00519995 |
| DENND5A | DENN/MADD domain containing 5A | -0.00518547 |
| GPX2 | glutathione peroxidase 2 | -0.00518225 |
