APCS Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description amyloid P component, serum|The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. [provided by RefSeq, Sep 2008] (NCBI Entrez Gene Database, 325)
External Link http://www.ncbi.nlm.nih.gov/gene/325
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91 interacting proteins for APCS from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
A1BG alpha-1-B glycoprotein
A2M alpha-2-macroglobulin
AHSG alpha-2-HS-glycoprotein
ALB albumin
APOA1 apolipoprotein A-I
APOA2 apolipoprotein A-II
APOA4 apolipoprotein A-IV
APOC1 apolipoprotein C-I
APOC2 apolipoprotein C-II
APOC3 apolipoprotein C-III
APOE apolipoprotein E
APOM apolipoprotein M
C1QA complement component 1, q subcomponent, A chain
C1R complement component 1, r subcomponent
C1S complement component 1, s subcomponent
C3 complement component 3
C4A complement component 4A (Rodgers blood group)
C4BPA complement component 4 binding protein, alpha
C4BPB complement component 4 binding protein, beta
C6 complement component 6
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CALU calumenin
CD5L CD5 molecule-like
CFH complement factor H
CLU clusterin
COL4A1 collagen, type IV, alpha 1
COL6A6 collagen, type VI, alpha 6
COPS5 COP9 signalosome subunit 5
CP ceruloplasmin (ferroxidase)
CRP C-reactive protein, pentraxin-related
DNA2 DNA replication helicase/nuclease 2
DUOX1 dual oxidase 1
EPYC epiphycan
F2 coagulation factor II (thrombin)
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
FN1 fibronectin 1
GC group-specific component (vitamin D binding protein)
GCC2 GRIP and coiled-coil domain containing 2
GK glycerol kinase
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial
GRB2 growth factor receptor-bound protein 2
HES1 hes family bHLH transcription factor 1
HNF1A HNF1 homeobox A
HNF4A hepatocyte nuclear factor 4, alpha
HP haptoglobin
HPR haptoglobin-related protein
HRG histidine-rich glycoprotein
IGFALS insulin-like growth factor binding protein, acid labile subunit
IGHG2 immunoglobulin heavy constant gamma 2 (G2m marker)
IGLC2 immunoglobulin lambda constant 2 (Kern-Oz- marker)
IGLL5 immunoglobulin lambda-like polypeptide 5
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
KIRREL kin of IRRE like (Drosophila)
KLC1 kinesin light chain 1
KNG1 kininogen 1
LAMA1 laminin, alpha 1
LUM lumican
ONECUT1 one cut homeobox 1
OPTN optineurin
ORM2 orosomucoid 2
PLG plasminogen
PON1 paraoxonase 1
PON3 paraoxonase 3
SAA2 serum amyloid A2
SAA4 serum amyloid A4, constitutive
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
SLC24A5 solute carrier family 24 (sodium/potassium/calcium exchanger), member 5
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
TG thyroglobulin
TTR transthyretin
UBE2L3 ubiquitin-conjugating enzyme E2L 3
VTN vitronectin