APECED - Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy_Thymic epithelial cell_GSE85 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE85
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Genes

600 genes differentially expressed during APECED - Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy_Thymic epithelial cell_GSE85 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
RBMS1 RNA binding motif, single stranded interacting protein 1 4.34726
KLHL9 kelch-like family member 9 4.14782
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 3.90063
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 3.86746
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 3.71592
TMED3 transmembrane emp24 protein transport domain containing 3 3.62974
GGPS1 geranylgeranyl diphosphate synthase 1 3.44386
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 3.4182
S100A4 S100 calcium binding protein A4 3.33795
SRSF9 serine/arginine-rich splicing factor 9 3.3167
KIF9 kinesin family member 9 3.28367
YES1 YES proto-oncogene 1, Src family tyrosine kinase 3.26574
NPC2 Niemann-Pick disease, type C2 3.0808
LUM lumican 3.0718
STK39 serine threonine kinase 39 3.06703
LZTFL1 leucine zipper transcription factor-like 1 3.04775
MRPS18A mitochondrial ribosomal protein S18A 3.02347
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) 2.91899
GPHN gephyrin 2.88961
AP1AR adaptor-related protein complex 1 associated regulatory protein 2.87954
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 2.85233
PHB2 prohibitin 2 2.80819
RNF6 ring finger protein (C3H2C3 type) 6 2.78084
SNAP91 synaptosomal-associated protein, 91kDa 2.75211
CCDC115 coiled-coil domain containing 115 2.71309
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 2.69283
CASP6 caspase 6, apoptosis-related cysteine peptidase 2.67719
CASP4 caspase 4, apoptosis-related cysteine peptidase 2.66046
PRPS1 phosphoribosyl pyrophosphate synthetase 1 2.65827
GRIA1 glutamate receptor, ionotropic, AMPA 1 2.64524
PIAS1 protein inhibitor of activated STAT, 1 2.63213
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled 2.6181
EEA1 early endosome antigen 1 2.60836
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 2.56226
RPL7 ribosomal protein L7 2.56104
ALDOA aldolase A, fructose-bisphosphate 2.53012
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 2.52378
IL15 interleukin 15 2.51703
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 2.50759
SRI sorcin 2.5043
PFKM phosphofructokinase, muscle 2.43212
UBL5 ubiquitin-like 5 2.43084
RNF167 ring finger protein 167 2.38338
GOLPH3 golgi phosphoprotein 3 (coat-protein) 2.3787
MEA1 male-enhanced antigen 1 2.35588
TXN thioredoxin 2.33797
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 2.33767
ATG12 autophagy related 12 2.33638
TRAPPC2L trafficking protein particle complex 2-like 2.32467
PRKCSH protein kinase C substrate 80K-H 2.3232
ZC3H14 zinc finger CCCH-type containing 14 2.28523
MRPL48 mitochondrial ribosomal protein L48 2.27
CRYL1 crystallin, lambda 1 2.26995
TBX15 T-box 15 2.26773
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1 2.25999
NSUN2 NOP2/Sun RNA methyltransferase family, member 2 2.25876
C14ORF166 chromosome 14 open reading frame 166 2.25203
GLTSCR2 glioma tumor suppressor candidate region gene 2 2.23867
STRN3 striatin, calmodulin binding protein 3 2.23008
B2M beta-2-microglobulin 2.21896
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa 2.20379
PRNP prion protein 2.17007
AKIRIN1 akirin 1 2.15611
SHMT1 serine hydroxymethyltransferase 1 (soluble) 2.15322
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 2.15061
TRIB3 tribbles pseudokinase 3 2.14376
RPL5 ribosomal protein L5 2.13501
S100A13 S100 calcium binding protein A13 2.13431
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 2.12583
DCTPP1 dCTP pyrophosphatase 1 2.12486
DTX2 deltex 2, E3 ubiquitin ligase 2.11013
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1) 2.09364
TRIAP1 TP53 regulated inhibitor of apoptosis 1 2.08136
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 2.07113
CDC42SE2 CDC42 small effector 2 2.06986
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 2.06822
TRAPPC4 trafficking protein particle complex 4 2.05963
SNCG synuclein, gamma (breast cancer-specific protein 1) 2.05305
ANAPC13 anaphase promoting complex subunit 13 2.05211
HAL histidine ammonia-lyase 2.04826
C8G complement component 8, gamma polypeptide 2.03721
TM2D1 TM2 domain containing 1 2.03047
SNAP47 synaptosomal-associated protein, 47kDa 2.02813
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 2.01452
BOK BCL2-related ovarian killer 2.00755
S100A6 S100 calcium binding protein A6 1.99551
C14ORF1 chromosome 14 open reading frame 1 1.98455
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 1.98014
DAP death-associated protein 1.97898
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.97433
DLX5 distal-less homeobox 5 1.97259
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 1.96611
MARCH5 membrane-associated ring finger (C3HC4) 5 1.96034
RPP30 ribonuclease P/MRP 30kDa subunit 1.9559
PRPF38B pre-mRNA processing factor 38B 1.95565
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa 1.95476
UBE2I ubiquitin-conjugating enzyme E2I 1.94988
HDAC2 histone deacetylase 2 1.94694
PDCD2 programmed cell death 2 1.94114
CCR7 chemokine (C-C motif) receptor 7 1.9368
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa 1.93614
RPL10 ribosomal protein L10 1.93359
HINT1 histidine triad nucleotide binding protein 1 1.93147
NUBP1 nucleotide binding protein 1 1.92291
JKAMP JNK1/MAPK8-associated membrane protein 1.91293
INTS8 integrator complex subunit 8 1.91045
ALAS2 5'-aminolevulinate synthase 2 1.90695
TUBA3E tubulin, alpha 3e 1.90117
SEC24B SEC24 family member B 1.89489
LIMS1 LIM and senescent cell antigen-like domains 1 1.89087
EPYC epiphycan 1.88149
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 1.87947
MCM10 minichromosome maintenance complex component 10 1.87829
WEE1 WEE1 G2 checkpoint kinase 1.87749
TMEM62 transmembrane protein 62 1.85134
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) 1.84966
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3 1.84599
PRKCZ protein kinase C, zeta 1.84292
RPL7A ribosomal protein L7a 1.83716
DSCR3 Down syndrome critical region 3 1.83198
IFT172 intraflagellar transport 172 1.82758
PAX2 paired box 2 1.8267
RPL10A ribosomal protein L10a 1.82311
HIST1H2BB histone cluster 1, H2bb 1.82249
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 1.79887
IGFBP4 insulin-like growth factor binding protein 4 1.78076
ITGA6 integrin, alpha 6 1.7792
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 1.76576
ING1 inhibitor of growth family, member 1 1.76557
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 1.75885
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.75795
SYF2 SYF2 pre-mRNA-splicing factor 1.74996
EOMES eomesodermin 1.74967
NICN1 nicolin 1 1.74701
RALB v-ral simian leukemia viral oncogene homolog B 1.74414
PRKCA protein kinase C, alpha 1.74249
PGK1 phosphoglycerate kinase 1 1.73277
DCTN5 dynactin 5 (p25) 1.73155
GDAP1 ganglioside induced differentiation associated protein 1 1.72857
MRPS14 mitochondrial ribosomal protein S14 1.72404
ORC5 origin recognition complex, subunit 5 1.71924
MRPL13 mitochondrial ribosomal protein L13 1.7144
MINPP1 multiple inositol-polyphosphate phosphatase 1 1.69994
PPP6C protein phosphatase 6, catalytic subunit 1.69829
STAG2 stromal antigen 2 1.69705
BMP2K BMP2 inducible kinase 1.69609
ZNF282 zinc finger protein 282 1.6959
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) 1.67991
AAAS achalasia, adrenocortical insufficiency, alacrimia 1.67154
IL1R2 interleukin 1 receptor, type II 1.65428
TRAF4 TNF receptor-associated factor 4 1.65231
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma 1.6485
MYDGF myeloid-derived growth factor 1.64767
JAK1 Janus kinase 1 1.6459
THOP1 thimet oligopeptidase 1 1.64015
RHOA ras homolog family member A 1.63696
LY9 lymphocyte antigen 9 1.63523
SOWAHC sosondowah ankyrin repeat domain family member C 1.62714
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) 1.6141
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 1.60776
TMEM70 transmembrane protein 70 1.60106
MMP16 matrix metallopeptidase 16 (membrane-inserted) 1.60055
CDC26 cell division cycle 26 1.59968
PACRGL PARK2 co-regulated-like 1.59128
EXOC8 exocyst complex component 8 1.58682
MTCH2 mitochondrial carrier 2 1.58123
SFXN4 sideroflexin 4 1.58026
SP3 Sp3 transcription factor 1.58014
TROVE2 TROVE domain family, member 2 1.57947
AKAP12 A kinase (PRKA) anchor protein 12 1.5793
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 1.57861
HLA-G major histocompatibility complex, class I, G 1.57833
MRPL24 mitochondrial ribosomal protein L24 1.57681
SNRPB2 small nuclear ribonucleoprotein polypeptide B 1.5734
CMTM7 CKLF-like MARVEL transmembrane domain containing 7 1.56967
PCCB propionyl CoA carboxylase, beta polypeptide 1.56324
COL14A1 collagen, type XIV, alpha 1 1.56279
NEURL3 neuralized E3 ubiquitin protein ligase 3 1.56055
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) 1.55795
BBS9 Bardet-Biedl syndrome 9 1.54575
ABHD16A abhydrolase domain containing 16A 1.5436
KITLG KIT ligand 1.53882
OSTF1 osteoclast stimulating factor 1 1.53446
MRPS24 mitochondrial ribosomal protein S24 1.53351
TPD52L2 tumor protein D52-like 2 1.53346
RBMX RNA binding motif protein, X-linked 1.53229
GAA glucosidase, alpha; acid 1.53015
IL7 interleukin 7 1.52254
ANGEL2 angel homolog 2 (Drosophila) 1.52118
LAMP2 lysosomal-associated membrane protein 2 1.51793
MRPL51 mitochondrial ribosomal protein L51 1.51523
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 1.51219
PTPN1 protein tyrosine phosphatase, non-receptor type 1 1.50974
CCNF cyclin F 1.50837
CYB5R4 cytochrome b5 reductase 4 1.50711
SMNDC1 survival motor neuron domain containing 1 1.50082
DPH5 diphthamide biosynthesis 5 1.49048
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) 1.48886
C1ORF43 chromosome 1 open reading frame 43 1.48774
TRIM13 tripartite motif containing 13 1.48513
FKBP2 FK506 binding protein 2, 13kDa 1.48094
MDFI MyoD family inhibitor 1.48094
PRKCD protein kinase C, delta 1.48085
COL19A1 collagen, type XIX, alpha 1 1.47888
RGS3 regulator of G-protein signaling 3 1.47717
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) 1.47634
SERINC3 serine incorporator 3 1.4748
RRAGC Ras-related GTP binding C 1.4649
GRK5 G protein-coupled receptor kinase 5 1.46449
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) 1.46058
FBN2 fibrillin 2 1.44972
MRPL17 mitochondrial ribosomal protein L17 1.44815
AEBP2 AE binding protein 2 1.44598
ZNF467 zinc finger protein 467 1.44533
ZNF706 zinc finger protein 706 1.44193
PDLIM1 PDZ and LIM domain 1 1.44165
HAGH hydroxyacylglutathione hydrolase 1.44147
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 1.43809
IL1RN interleukin 1 receptor antagonist 1.43711
RAP1A RAP1A, member of RAS oncogene family 1.43674
IL4 interleukin 4 1.43258
WARS tryptophanyl-tRNA synthetase 1.43035
RPLP0 ribosomal protein, large, P0 1.42151
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.42043
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 1.41907
PCNA proliferating cell nuclear antigen 1.40869
RYK receptor-like tyrosine kinase 1.40659
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like 1.40533
RNF20 ring finger protein 20, E3 ubiquitin protein ligase 1.40527
TRAPPC1 trafficking protein particle complex 1 1.40488
GNPDA1 glucosamine-6-phosphate deaminase 1 1.40312
RAB14 RAB14, member RAS oncogene family 1.39859
MCFD2 multiple coagulation factor deficiency 2 1.39671
SON SON DNA binding protein 1.39598
LOC93432 1.3956
HLA-DOA major histocompatibility complex, class II, DO alpha 1.39085
TMEM179B transmembrane protein 179B 1.39014
TOR1B torsin family 1, member B (torsin B) 1.38844
TBC1D21 TBC1 domain family, member 21 1.38741
DLG1 discs, large homolog 1 (Drosophila) 1.3867
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 1.38441
MRPL45 mitochondrial ribosomal protein L45 1.38219
ABLIM1 actin binding LIM protein 1 1.38168
C19ORF70 chromosome 19 open reading frame 70 1.37732
DOCK9 dedicator of cytokinesis 9 1.37696
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 1.37609
AKAP8L A kinase (PRKA) anchor protein 8-like 1.37308
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 1.36898
UBL3 ubiquitin-like 3 1.36649
C1QBP complement component 1, q subcomponent binding protein 1.36547
MRPL2 mitochondrial ribosomal protein L2 1.36469
IFI35 interferon-induced protein 35 1.35856
ERO1LB ERO1-like beta (S. cerevisiae) 1.35692
KLHDC4 kelch domain containing 4 1.3563
DAPK2 death-associated protein kinase 2 1.34965
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 1.34803
PGM1 phosphoglucomutase 1 1.34718
MRPL18 mitochondrial ribosomal protein L18 1.34397
FKBP11 FK506 binding protein 11, 19 kDa 1.34349
FAM134B family with sequence similarity 134, member B 1.34154
FCRLA Fc receptor-like A 1.33396
RAE1 ribonucleic acid export 1 1.3315
RPRM reprimo, TP53 dependent G2 arrest mediator candidate 1.33107
SENP6 SUMO1/sentrin specific peptidase 6 1.32742
FSIP1 fibrous sheath interacting protein 1 1.3272
HBS1L HBS1-like translational GTPase 1.32711
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 1.3217
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 1.31879
ANTXR2 anthrax toxin receptor 2 1.31809
RAB4B RAB4B, member RAS oncogene family 1.31755
NFIA nuclear factor I/A 1.31247
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 1.31156
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 1.30882
TPI1 triosephosphate isomerase 1 1.30766
NCF2 neutrophil cytosolic factor 2 1.30501
LY75 lymphocyte antigen 75 1.29614
PON1 paraoxonase 1 1.29567
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 1.29408
HNF1B HNF1 homeobox B 1.28857
MAF1 MAF1 homolog (S. cerevisiae) 1.28681
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 1.28374
BST1 bone marrow stromal cell antigen 1 1.28331
TMPO thymopoietin 1.28014
WNT3 wingless-type MMTV integration site family, member 3 1.27793
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) 1.27631
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) 1.27496
INSM1 insulinoma-associated 1 1.27495
RNF11 ring finger protein 11 1.27467
TST thiosulfate sulfurtransferase (rhodanese) 1.27385
SHFM1 split hand/foot malformation (ectrodactyly) type 1 1.27216
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent 1.27213
ACTR6 ARP6 actin-related protein 6 homolog (yeast) 1.26863
BET1L Bet1 golgi vesicular membrane trafficking protein-like 1.26608
NDNL2 necdin-like 2 1.26464
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase 1.26242
APC adenomatous polyposis coli 1.2612
PDCD2L programmed cell death 2-like 1.26118
PQLC3 PQ loop repeat containing 3 1.25821
RER1 retention in endoplasmic reticulum sorting receptor 1 1.254
RAD50 RAD50 homolog (S. cerevisiae) 1.25213

decreased expression

Symbol Name Standardized Value
PTPRE protein tyrosine phosphatase, receptor type, E -4.38787
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -4.1224
FABP2 fatty acid binding protein 2, intestinal -4.10689
RAB4A RAB4A, member RAS oncogene family -3.91849
CDC25A cell division cycle 25A -3.83133
NR4A1 nuclear receptor subfamily 4, group A, member 1 -3.52723
UBE2N ubiquitin-conjugating enzyme E2N -3.45832
PGLYRP1 peptidoglycan recognition protein 1 -3.28552
GFI1B growth factor independent 1B transcription repressor -3.19366
DMBT1 deleted in malignant brain tumors 1 -3.158
NPY neuropeptide Y -3.01407
H19 H19, imprinted maternally expressed transcript (non-protein coding) -2.97374
CCK cholecystokinin -2.87855
HIST1H1T histone cluster 1, H1t -2.85814
HOPX HOP homeobox -2.80952
VIPR1 vasoactive intestinal peptide receptor 1 -2.79384
SYAP1 synapse associated protein 1 -2.77341
NOTCH3 notch 3 -2.7498
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13 -2.69535
AHCY adenosylhomocysteinase -2.69127
SPIC Spi-C transcription factor (Spi-1/PU.1 related) -2.65826
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa -2.61565
ZP1 zona pellucida glycoprotein 1 (sperm receptor) -2.61108
INS insulin -2.60324
NFIB nuclear factor I/B -2.58411
FKBP4 FK506 binding protein 4, 59kDa -2.55022
CCRL2 chemokine (C-C motif) receptor-like 2 -2.52358
DSTN destrin (actin depolymerizing factor) -2.50022
TFF3 trefoil factor 3 (intestinal) -2.49259
REG3A regenerating islet-derived 3 alpha -2.44412
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 -2.43198
FGB fibrinogen beta chain -2.42114
ZNHIT3 zinc finger, HIT-type containing 3 -2.41839
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase -2.41751
TH tyrosine hydroxylase -2.37153
GFRA3 GDNF family receptor alpha 3 -2.36292
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -2.3629
AMPD3 adenosine monophosphate deaminase 3 -2.34084
APOC2 apolipoprotein C-II -2.33879
ANK1 ankyrin 1, erythrocytic -2.31955
PTX3 pentraxin 3, long -2.31517
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant -2.30812
CDC6 cell division cycle 6 -2.23096
FN1 fibronectin 1 -2.1932
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein -2.18739
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) -2.18503
TAC1 tachykinin, precursor 1 -2.17456
FAM65B family with sequence similarity 65, member B -2.14626
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 -2.09369
ATF3 activating transcription factor 3 -2.08108
HHEX hematopoietically expressed homeobox -2.07301
CTC1 CTS telomere maintenance complex component 1 -2.06761
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 -2.0614
NODAL nodal growth differentiation factor -2.05663
IGF2 insulin-like growth factor 2 -2.0464
CAPN5 calpain 5 -2.03317
PNPT1 polyribonucleotide nucleotidyltransferase 1 -2.02641
APOA1 apolipoprotein A-I -2.02629
FIGF c-fos induced growth factor (vascular endothelial growth factor D) -2.0214
CXCR4 chemokine (C-X-C motif) receptor 4 -1.99894
BGN biglycan -1.99894
RGS16 regulator of G-protein signaling 16 -1.99422
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1 -1.989
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 -1.98647
STAT4 signal transducer and activator of transcription 4 -1.95367
DNM1 dynamin 1 -1.94454
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 -1.93431
ARL4D ADP-ribosylation factor-like 4D -1.92304
NDRG2 NDRG family member 2 -1.91794
MBL2 mannose-binding lectin (protein C) 2, soluble -1.89303
BEX4 brain expressed, X-linked 4 -1.84916
KRT12 keratin 12, type I -1.83757
ATOH1 atonal homolog 1 (Drosophila) -1.8366
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 -1.83086
RAPSN receptor-associated protein of the synapse -1.82855
PTHLH parathyroid hormone-like hormone -1.81993
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -1.81725
CUZD1 CUB and zona pellucida-like domains 1 -1.78438
XPC xeroderma pigmentosum, complementation group C -1.76849
SYTL4 synaptotagmin-like 4 -1.73985
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -1.73507
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 -1.72564
FKBP9 FK506 binding protein 9, 63 kDa -1.7029
ELL2 elongation factor, RNA polymerase II, 2 -1.70217
CGA glycoprotein hormones, alpha polypeptide -1.70085
RNF166 ring finger protein 166 -1.6831
CKB creatine kinase, brain -1.67868
TTL tubulin tyrosine ligase -1.67759
MUC5AC mucin 5AC, oligomeric mucus/gel-forming -1.64457
FAAH fatty acid amide hydrolase -1.64454
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -1.63777
DTD1 D-tyrosyl-tRNA deacylase 1 -1.63461
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide -1.63285
IFIH1 interferon induced with helicase C domain 1 -1.6324
ALDOB aldolase B, fructose-bisphosphate -1.63004
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) -1.62651
MAPT microtubule-associated protein tau -1.61052
KRT32 keratin 32, type I -1.60899
CREM cAMP responsive element modulator -1.6076
LBP lipopolysaccharide binding protein -1.60666
LDHB lactate dehydrogenase B -1.60597
CHEK2 checkpoint kinase 2 -1.60491
CCDC94 coiled-coil domain containing 94 -1.60088
PSEN1 presenilin 1 -1.58901
CXCL2 chemokine (C-X-C motif) ligand 2 -1.58194
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -1.57754
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa -1.57432
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 -1.57137
ACE2 angiotensin I converting enzyme 2 -1.56922
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) -1.55397
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 -1.5505
CXCL3 chemokine (C-X-C motif) ligand 3 -1.55044
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -1.54076
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa -1.52971
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 -1.52967
TXNRD1 thioredoxin reductase 1 -1.5249
HBZ hemoglobin, zeta -1.52207
ILVBL ilvB (bacterial acetolactate synthase)-like -1.51741
ALOX15 arachidonate 15-lipoxygenase -1.51141
ZNF703 zinc finger protein 703 -1.50975
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -1.48737
SMS spermine synthase -1.48065
IL12B interleukin 12B -1.47789
CNOT6L CCR4-NOT transcription complex, subunit 6-like -1.47319
PCDHA13 protocadherin alpha 13 -1.47012
RAP2B RAP2B, member of RAS oncogene family -1.46791
RFC2 replication factor C (activator 1) 2, 40kDa -1.45504
ACAA1 acetyl-CoA acyltransferase 1 -1.44312
IL5 interleukin 5 -1.44075
CBX6 chromobox homolog 6 -1.43836
KRT84 keratin 84, type II -1.43454
CTRB2 chymotrypsinogen B2 -1.4328
SLC22A18 solute carrier family 22, member 18 -1.42936
MLX MLX, MAX dimerization protein -1.42913
MUC13 mucin 13, cell surface associated -1.42463
CRABP1 cellular retinoic acid binding protein 1 -1.41813
MYOM1 myomesin 1 -1.41658
PHTF2 putative homeodomain transcription factor 2 -1.41241
ATP7A ATPase, Cu++ transporting, alpha polypeptide -1.41141
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -1.40926
UGP2 UDP-glucose pyrophosphorylase 2 -1.40691
CENPV centromere protein V -1.40501
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F -1.37583
SELP selectin P (granule membrane protein 140kDa, antigen CD62) -1.36784
GSTM3 glutathione S-transferase mu 3 (brain) -1.36735
ADAMDEC1 ADAM-like, decysin 1 -1.36542
RAB31 RAB31, member RAS oncogene family -1.36227
IL6ST interleukin 6 signal transducer -1.34877
PRSS1 protease, serine, 1 (trypsin 1) -1.34865
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 -1.34728
C9ORF16 chromosome 9 open reading frame 16 -1.34565
CELA2A chymotrypsin-like elastase family, member 2A -1.3394
T T, brachyury homolog (mouse) -1.3371
FOXA3 forkhead box A3 -1.33412
MYO1B myosin IB -1.33286
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 -1.3272
FAM171A1 family with sequence similarity 171, member A1 -1.32628
GIF gastric intrinsic factor (vitamin B synthesis) -1.32494
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 -1.31359
TAC3 tachykinin 3 -1.30194
SAAL1 serum amyloid A-like 1 -1.30073
WISP1 WNT1 inducible signaling pathway protein 1 -1.29922
PTGDS prostaglandin D2 synthase 21kDa (brain) -1.28108
SUV420H2 suppressor of variegation 4-20 homolog 2 (Drosophila) -1.27819
MMP14 matrix metallopeptidase 14 (membrane-inserted) -1.2597
GBX2 gastrulation brain homeobox 2 -1.25122
NANOG Nanog homeobox -1.2483
SMYD1 SET and MYND domain containing 1 -1.24213
PCSK4 proprotein convertase subtilisin/kexin type 4 -1.24176
GCGR glucagon receptor -1.23782
FABP6 fatty acid binding protein 6, ileal -1.23678
FABP3 fatty acid binding protein 3, muscle and heart -1.23625
COL18A1 collagen, type XVIII, alpha 1 -1.23623
MPP7 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) -1.23574
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) -1.23431
SAA1 serum amyloid A1 -1.22994
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase -1.21421
IGFBP6 insulin-like growth factor binding protein 6 -1.21187
ACTC1 actin, alpha, cardiac muscle 1 -1.19742
TCL1A T-cell leukemia/lymphoma 1A -1.19617
GAS2 growth arrest-specific 2 -1.19247
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -1.19128
GIP gastric inhibitory polypeptide -1.19106
LY6E lymphocyte antigen 6 complex, locus E -1.18682
GABARAPL1 GABA(A) receptor-associated protein like 1 -1.18393
ANG angiogenin, ribonuclease, RNase A family, 5 -1.18357
RECQL RecQ helicase-like -1.18295
KHDC1L KH homology domain containing 1-like -1.18139
CLEC4F C-type lectin domain family 4, member F -1.17884
FXYD3 FXYD domain containing ion transport regulator 3 -1.17672
MAP3K3 mitogen-activated protein kinase kinase kinase 3 -1.17667
TMED4 transmembrane emp24 protein transport domain containing 4 -1.16535
POMC proopiomelanocortin -1.16323
CAMP cathelicidin antimicrobial peptide -1.16115
CCL3L3 chemokine (C-C motif) ligand 3-like 3 -1.15877
PPY pancreatic polypeptide -1.1563
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 -1.15319
ODC1 ornithine decarboxylase 1 -1.13469
TAGLN2 transgelin 2 -1.13228
SIAH2 siah E3 ubiquitin protein ligase 2 -1.13055
SLC35E4 solute carrier family 35, member E4 -1.12869
SLC30A3 solute carrier family 30 (zinc transporter), member 3 -1.12573
RBP4 retinol binding protein 4, plasma -1.12366
MIS18A MIS18 kinetochore protein A -1.12345
KRTAP13-2 keratin associated protein 13-2 -1.12162
TES testin LIM domain protein -1.11944
SPP1 secreted phosphoprotein 1 -1.10883
SPRR1A small proline-rich protein 1A -1.10835
COL8A1 collagen, type VIII, alpha 1 -1.10573
MPO myeloperoxidase -1.10277
GLUL glutamate-ammonia ligase -1.10045
TCN2 transcobalamin II -1.09915
EMP2 epithelial membrane protein 2 -1.09209
G6PC glucose-6-phosphatase, catalytic subunit -1.09206
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 -1.08469
MYO7A myosin VIIA -1.08346
DDHD2 DDHD domain containing 2 -1.08275
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 -1.08213
MORC4 MORC family CW-type zinc finger 4 -1.07764
TXN2 thioredoxin 2 -1.07338
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28 -1.07306
FMO1 flavin containing monooxygenase 1 -1.07106
PROCR protein C receptor, endothelial -1.06808
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 -1.06725
TCEA2 transcription elongation factor A (SII), 2 -1.0657
SIX2 SIX homeobox 2 -1.0646
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) -1.06377
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 -1.06368
MOBP myelin-associated oligodendrocyte basic protein -1.06366
SCG3 secretogranin III -1.06361
MAP2K3 mitogen-activated protein kinase kinase 3 -1.06215
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa -1.06132
INTS7 integrator complex subunit 7 -1.0566
MYOC myocilin, trabecular meshwork inducible glucocorticoid response -1.05549
GPX3 glutathione peroxidase 3 -1.05476
AURKA aurora kinase A -1.05342
SSTR2 somatostatin receptor 2 -1.05157
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 -1.04803
MDH2 malate dehydrogenase 2, NAD (mitochondrial) -1.04302
ELAC2 elaC ribonuclease Z 2 -1.04205
RLN1 relaxin 1 -1.03841
GOLIM4 golgi integral membrane protein 4 -1.03671
CMTM4 CKLF-like MARVEL transmembrane domain containing 4 -1.03572
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) -1.0333
SSR1 signal sequence receptor, alpha -1.02789
SOX2 SRY (sex determining region Y)-box 2 -1.02634
SOWAHA sosondowah ankyrin repeat domain family member A -1.02578
CLU clusterin -1.02243
CALML4 calmodulin-like 4 -1.02128
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -1.02099
SLPI secretory leukocyte peptidase inhibitor -1.01783
FABP9 fatty acid binding protein 9, testis -1.01683
PTPRF protein tyrosine phosphatase, receptor type, F -1.01662
DPPA5 developmental pluripotency associated 5 -1.01556
MYT1 myelin transcription factor 1 -1.01497
LGALS9B lectin, galactoside-binding, soluble, 9B -1.01268
PPP2R1B protein phosphatase 2, regulatory subunit A, beta -1.01232
DRD2 dopamine receptor D2 -1.01159
PIM2 Pim-2 proto-oncogene, serine/threonine kinase -1.0113
LATS2 large tumor suppressor kinase 2 -1.01072
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -1.0105
DPEP1 dipeptidase 1 (renal) -1.00949
SDC1 syndecan 1 -1.00727
HCK HCK proto-oncogene, Src family tyrosine kinase -1.00575
SCG2 secretogranin II -1.00489
EHF ets homologous factor -1.00225
ADSSL1 adenylosuccinate synthase like 1 -1.00181
KL klotho -1.00013
CTPS1 CTP synthase 1 -0.995495
MLF1 myeloid leukemia factor 1 -0.994659
PRDX6 peroxiredoxin 6 -0.992963
NOP58 NOP58 ribonucleoprotein -0.991705
MLPH melanophilin -0.991238
APOF apolipoprotein F -0.989615
CCL5 chemokine (C-C motif) ligand 5 -0.989479
RHOJ ras homolog family member J -0.989315
GNB5 guanine nucleotide binding protein (G protein), beta 5 -0.985348
KCNK2 potassium channel, two pore domain subfamily K, member 2 -0.982362
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) -0.981522
UNC13B unc-13 homolog B (C. elegans) -0.97644
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 -0.976156
E2F3 E2F transcription factor 3 -0.97383
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 -0.970156
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 -0.968903
PAX1 paired box 1 -0.967522
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.9666
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.965082
OCM oncomodulin -0.964678
GAST gastrin -0.963069
ANXA2 annexin A2 -0.962058
SLC44A1 solute carrier family 44 (choline transporter), member 1 -0.960731
IBSP integrin-binding sialoprotein -0.959258
CDK18 cyclin-dependent kinase 18 -0.958308
CDR2 cerebellar degeneration-related protein 2, 62kDa -0.955375
CLEC3B C-type lectin domain family 3, member B -0.951659
GPN2 GPN-loop GTPase 2 -0.949846
RHOU ras homolog family member U -0.947832
RSAD2 radical S-adenosyl methionine domain containing 2 -0.946501
CBR1 carbonyl reductase 1 -0.943881
DCAF12 DDB1 and CUL4 associated factor 12 -0.942975