| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | APEX nuclease (multifunctional DNA repair enzyme) 1|Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 328) |
| External Link | https://ncbi.nlm.nih.gov/gene/328 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the APEX1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TNC | tenascin C | 0.0142674 |
| MMP1 | matrix metallopeptidase 1 | 0.0126553 |
| FASN | fatty acid synthase | 0.0110292 |
| TFF3 | trefoil factor 3 (intestinal) | 0.0108008 |
| BEX1 | brain expressed, X-linked 1 | 0.0105124 |
| CTSZ | cathepsin Z | 0.0103613 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.0102791 |
| HOXC6 | homeobox C6 | 0.00996781 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00983328 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.00981706 |
| RAPSN | receptor-associated protein of the synapse | 0.00944999 |
| CIT | citron rho-interacting serine/threonine kinase | 0.00902756 |
| RGS5 | regulator of G-protein signaling 5 | 0.00884176 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | 0.00878389 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.00873085 |
| FOXF1 | forkhead box F1 | 0.00854448 |
| SDC2 | syndecan 2 | 0.00850773 |
| INSR | insulin receptor | 0.00842445 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.00837736 |
| MAP7 | microtubule-associated protein 7 | 0.00795294 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.00785039 |
| CALD1 | caldesmon 1 | 0.0078213 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.00768208 |
| PRDX2 | peroxiredoxin 2 | 0.00766185 |
| MAOA | monoamine oxidase A | 0.00759121 |
| MSN | moesin | 0.00754653 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | 0.00752591 |
| CBX6 | chromobox homolog 6 | 0.0075191 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | 0.00751126 |
| CBX1 | chromobox homolog 1 | 0.00743546 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.00742851 |
| PLAT | plasminogen activator, tissue | 0.00740423 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00740093 |
| FCGBP | Fc fragment of IgG binding protein | 0.00727555 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00724566 |
| TFDP1 | transcription factor Dp-1 | 0.00714007 |
| IPO13 | importin 13 | 0.00713423 |
| TMEM176B | transmembrane protein 176B | 0.00705727 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.00704187 |
| HMGB1 | high mobility group box 1 | 0.00702997 |
| ADCY1 | adenylate cyclase 1 (brain) | 0.00700786 |
| HIP1 | huntingtin interacting protein 1 | 0.00700664 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.0069695 |
| BRD2 | bromodomain containing 2 | 0.00696502 |
| CA9 | carbonic anhydrase IX | 0.00693351 |
| DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A | 0.00692015 |
| IPO5 | importin 5 | 0.00691059 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 0.0069074 |
| PNN | pinin, desmosome associated protein | 0.00685988 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.00684853 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.00682963 |
| OLFM1 | olfactomedin 1 | 0.00681262 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | 0.00663244 |
| XPO7 | exportin 7 | 0.00662353 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.00661359 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 | 0.00660935 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.00660095 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 | 0.00658551 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.00657435 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | 0.00650453 |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) | 0.00646781 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.00644856 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.00644528 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.00644498 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.00644032 |
| TOX3 | TOX high mobility group box family member 3 | 0.00643245 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.00640354 |
| MTA1 | metastasis associated 1 | 0.00640072 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00637375 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.00636066 |
| FADS1 | fatty acid desaturase 1 | 0.00625774 |
| WWC3 | WWC family member 3 | 0.0062505 |
| CYTH1 | cytohesin 1 | 0.00622914 |
| ADORA2B | adenosine A2b receptor | 0.00622203 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | 0.00620172 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.00619432 |
| SATB2 | SATB homeobox 2 | 0.00619048 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | 0.00618754 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | 0.00617097 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | 0.00616961 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) | 0.00613549 |
| FAM13A | family with sequence similarity 13, member A | 0.00609681 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.00609151 |
| TFF1 | trefoil factor 1 | 0.00607038 |
| ASPH | aspartate beta-hydroxylase | 0.00603877 |
| ELAC2 | elaC ribonuclease Z 2 | 0.00599515 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00593857 |
| HMGB3 | high mobility group box 3 | 0.00591593 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 | 0.00589313 |
| KLF13 | Kruppel-like factor 13 | 0.00588939 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | 0.00588921 |
| GSTA1 | glutathione S-transferase alpha 1 | 0.00588357 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.00587994 |
| DHFR | dihydrofolate reductase | 0.00587916 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | 0.00586946 |
| REG1A | regenerating islet-derived 1 alpha | 0.00585038 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.00582699 |
| CLIC4 | chloride intracellular channel 4 | 0.00582204 |
| TUBB3 | tubulin, beta 3 class III | 0.00579212 |
| CBX5 | chromobox homolog 5 | 0.00578964 |
| LMNB2 | lamin B2 | 0.00578471 |
| CALCA | calcitonin-related polypeptide alpha | 0.00577942 |
| MCF2L | MCF.2 cell line derived transforming sequence-like | 0.00577786 |
| MED1 | mediator complex subunit 1 | 0.005775 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.00576858 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0057662 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00575917 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.00575568 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.0057372 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.00573414 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00573204 |
| PRPF3 | pre-mRNA processing factor 3 | 0.00573139 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.00571227 |
| ANKRD11 | ankyrin repeat domain 11 | 0.00570696 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00570548 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.00570397 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.00570244 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | 0.00569357 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 | 0.00568027 |
| GET1 | guided entry of tail-anchored proteins factor 1 | 0.00567677 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 | 0.00567508 |
| KIF14 | kinesin family member 14 | 0.00564137 |
| CCL13 | chemokine (C-C motif) ligand 13 | 0.00564129 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.00563696 |
| KPNB1 | karyopherin (importin) beta 1 | 0.00563064 |
| MMP3 | matrix metallopeptidase 3 | 0.00562392 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.00562388 |
| C6 | complement component 6 | 0.005623 |
| CRLF1 | cytokine receptor-like factor 1 | 0.00562258 |
| KHK | ketohexokinase (fructokinase) | 0.00560278 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 0.00558658 |
| TXLNA | taxilin alpha | 0.0055844 |
| MTARC1 | mitochondrial amidoxime reducing component 1 | 0.00558313 |
| TUBB4B | tubulin, beta 4B class IVb | 0.00558055 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | 0.00557896 |
| REC8 | REC8 meiotic recombination protein | 0.0055785 |
| TCERG1 | transcription elongation regulator 1 | 0.00557136 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.00557112 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.00556772 |
| TM7SF2 | transmembrane 7 superfamily member 2 | 0.0055616 |
| PRRC2A | proline-rich coiled-coil 2A | 0.00556147 |
| PLK1 | polo-like kinase 1 | 0.00554048 |
| ACKR3 | atypical chemokine receptor 3 | 0.00550277 |
| TARDBP | TAR DNA binding protein | 0.00549602 |
| TLR4 | toll-like receptor 4 | 0.00548039 |
| PCDH17 | protocadherin 17 | 0.00547686 |
| PRNP | prion protein | 0.00545993 |
| TBC1D16 | TBC1 domain family, member 16 | 0.00545532 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | 0.00545094 |
| IPO9 | importin 9 | 0.00544866 |
| RUFY3 | RUN and FYVE domain containing 3 | 0.00544065 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.0054398 |
| UFL1 | UFM1-specific ligase 1 | 0.00543066 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.00543033 |
| TRIP13 | thyroid hormone receptor interactor 13 | 0.0054096 |
| SETBP1 | SET binding protein 1 | 0.00540953 |
| HOXC10 | homeobox C10 | 0.00540301 |
| PRC1 | protein regulator of cytokinesis 1 | 0.00539671 |
| PAXIP1 | PAX interacting (with transcription-activation domain) protein 1 | 0.00539621 |
| MPDZ | multiple PDZ domain protein | 0.0053745 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 | 0.00533981 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.00533611 |
| KIF5B | kinesin family member 5B | 0.00532742 |
| SQLE | squalene epoxidase | 0.00532394 |
| IRF8 | interferon regulatory factor 8 | 0.00532266 |
| LMAN1 | lectin, mannose-binding, 1 | 0.00531185 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | 0.00531136 |
| RTN3 | reticulon 3 | 0.00530177 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.00529841 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.00529276 |
| HDAC6 | histone deacetylase 6 | 0.0052919 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) | 0.00528893 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | 0.00527286 |
| DEK | DEK proto-oncogene | 0.00526955 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.00526557 |
| HMG20B | high mobility group 20B | 0.00526539 |
| REG1B | regenerating islet-derived 1 beta | 0.00523224 |
| INSIG1 | insulin induced gene 1 | 0.00522941 |
| BHMT | betaine--homocysteine S-methyltransferase | 0.00522695 |
| HMGB2 | high mobility group box 2 | 0.00522016 |
| PCGF2 | polycomb group ring finger 2 | 0.00521753 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | 0.00521226 |
| CNPY3 | canopy FGF signaling regulator 3 | 0.00520939 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0052047 |
| CREB1 | cAMP responsive element binding protein 1 | 0.00520448 |
| CTR9 | CTR9, Paf1/RNA polymerase II complex component | 0.00519757 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00518744 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00518293 |
| SFTPC | surfactant protein C | 0.00516937 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.00516849 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 | 0.00516802 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.00515681 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 | 0.00513115 |
| PSRC1 | proline/serine-rich coiled-coil 1 | 0.00512632 |
| CD209 | CD209 molecule | 0.00512075 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | 0.00511485 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.00509889 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.00509027 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.00508879 |
| ICMT | isoprenylcysteine carboxyl methyltransferase | 0.00508426 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.00507368 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.00506906 |
| SPAG5 | sperm associated antigen 5 | 0.00506017 |
| CALR | calreticulin | 0.00504942 |
| CTBP2 | C-terminal binding protein 2 | 0.005046 |
| ETV1 | ets variant 1 | 0.0050441 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.00503378 |
| RPA3 | replication protein A3, 14kDa | 0.0050268 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | 0.00501755 |
| SMTN | smoothelin | 0.00501649 |
| SEPTIN10 | septin 10 | 0.00501328 |
| CES3 | carboxylesterase 3 | 0.00500817 |
| FEN1 | flap structure-specific endonuclease 1 | 0.00499338 |
| MCM3 | minichromosome maintenance complex component 3 | 0.00498525 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | 0.00497957 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.00496042 |
| NVL | nuclear VCP-like | 0.00495311 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 0.00495301 |
| ACO1 | aconitase 1, soluble | 0.0049409 |
| FAM3C | family with sequence similarity 3, member C | 0.00491605 |
| DKFZP586I1420 | uncharacterized protein DKFZp586I1420 | 0.00490512 |
| EVA1B | eva-1 homolog B (C. elegans) | 0.00490324 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 0.00489904 |
| CNOT7 | CCR4-NOT transcription complex, subunit 7 | 0.00489212 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | 0.00488523 |
| RRM1 | ribonucleotide reductase M1 | 0.00488375 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.00488051 |
| GTSE1 | G-2 and S-phase expressed 1 | 0.0048713 |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 | 0.00485501 |
| ELANE | elastase, neutrophil expressed | 0.00484603 |
| POLD2 | polymerase (DNA directed), delta 2, accessory subunit | 0.00484328 |
| CEP170B | centrosomal protein 170B | 0.00484148 |
| CEP43 | centrosomal protein 43 | 0.00483654 |
| LIG1 | ligase I, DNA, ATP-dependent | 0.00482431 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | 0.00479637 |
| MGAT4B | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B | 0.00479366 |
| MELK | maternal embryonic leucine zipper kinase | 0.00479353 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0047909 |
| CDCA4 | cell division cycle associated 4 | 0.00478798 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0047864 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | 0.00478454 |
| MLEC | malectin | 0.0047829 |
| METTL7A | methyltransferase like 7A | 0.00478261 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.00477522 |
| CDK6 | cyclin-dependent kinase 6 | 0.00476215 |
| TMEM176A | transmembrane protein 176A | 0.00475772 |
| CD99 | CD99 molecule | 0.00475267 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.0047499 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.00474629 |
| MAPRE2 | microtubule-associated protein, RP/EB family, member 2 | 0.0047453 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MYBPC1 | myosin binding protein C, slow type | -0.0154221 |
| S100P | S100 calcium binding protein P | -0.0154118 |
| LTF | lactotransferrin | -0.0153833 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0152726 |
| MMP7 | matrix metallopeptidase 7 | -0.0144473 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.0142116 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.0138764 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.0133508 |
| LCN2 | lipocalin 2 | -0.0126504 |
| ATF3 | activating transcription factor 3 | -0.0126466 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.0124751 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.0122166 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0117498 |
| CSTA | cystatin A (stefin A) | -0.0117387 |
| TNNC1 | troponin C type 1 (slow) | -0.0114952 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.0112764 |
| CRYAB | crystallin, alpha B | -0.0110429 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.01104 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.010977 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0108696 |
| COCH | cochlin | -0.0107911 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.010701 |
| TPD52L1 | tumor protein D52-like 1 | -0.0106947 |
| KYNU | kynureninase | -0.0106672 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0104835 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0104017 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0103512 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0100772 |
| VAMP8 | vesicle-associated membrane protein 8 | -0.00990995 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00988246 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00984444 |
| GPM6B | glycoprotein M6B | -0.00970663 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00963818 |
| KRT5 | keratin 5, type II | -0.00953401 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | -0.00947481 |
| CD52 | CD52 molecule | -0.00937242 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00936777 |
| MT1X | metallothionein 1X | -0.00921588 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.00896975 |
| COG7 | component of oligomeric golgi complex 7 | -0.00892439 |
| S100A8 | S100 calcium binding protein A8 | -0.00881944 |
| FABP7 | fatty acid binding protein 7, brain | -0.00879288 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.00877153 |
| RCAN1 | regulator of calcineurin 1 | -0.00874403 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00870334 |
| KLHL41 | kelch-like family member 41 | -0.00851922 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.00851149 |
| NRCAM | neuronal cell adhesion molecule | -0.0084806 |
| LY75 | lymphocyte antigen 75 | -0.00845581 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | -0.00840013 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.00837988 |
| DCN | decorin | -0.0083462 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | -0.00829987 |
| CYB5R1 | cytochrome b5 reductase 1 | -0.00829574 |
| PLBD1 | phospholipase B domain containing 1 | -0.0082884 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.00825664 |
| SLN | sarcolipin | -0.00823064 |
| MB | myoglobin | -0.00820106 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00820089 |
| TARP | TCR gamma alternate reading frame protein | -0.00819642 |
| S100A9 | S100 calcium binding protein A9 | -0.00817222 |
| PRAME | preferentially expressed antigen in melanoma | -0.00817187 |
| GMPR | guanosine monophosphate reductase | -0.00816065 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.00806485 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -0.00792994 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00792265 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00782187 |
| GYG1 | glycogenin 1 | -0.00778768 |
| BEX4 | brain expressed, X-linked 4 | -0.00777868 |
| KRT14 | keratin 14, type I | -0.00776311 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.0077242 |
| TSPAN8 | tetraspanin 8 | -0.00769086 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00768404 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00765925 |
| CKM | creatine kinase, muscle | -0.00762683 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | -0.007624 |
| PEG10 | paternally expressed 10 | -0.00757424 |
| KRT19 | keratin 19, type I | -0.00756648 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | -0.00756358 |
| EPCAM | epithelial cell adhesion molecule | -0.00754819 |
| STXBP2 | syntaxin binding protein 2 | -0.00754661 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.00754657 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.00752419 |
| KRT15 | keratin 15, type I | -0.00751976 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00751765 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | -0.00751385 |
| MT1G | metallothionein 1G | -0.00746771 |
| MYO1C | myosin IC | -0.00743301 |
| ADD3 | adducin 3 (gamma) | -0.00741492 |
| ANXA1 | annexin A1 | -0.00740765 |
| PSAP | prosaposin | -0.00739959 |
| CALB1 | calbindin 1, 28kDa | -0.0073915 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00737871 |
| ANXA4 | annexin A4 | -0.00737674 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.00732541 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.00730952 |
| C10ORF10 | chromosome 10 open reading frame 10 | -0.00728305 |
| ECM1 | extracellular matrix protein 1 | -0.00724777 |
| MRPS16 | mitochondrial ribosomal protein S16 | -0.00724669 |
| YPEL5 | yippee-like 5 (Drosophila) | -0.00723214 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00718573 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | -0.00715786 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.00714842 |
| EGR2 | early growth response 2 | -0.0071474 |
| IER5 | immediate early response 5 | -0.00714198 |
| SH3BGR | SH3 domain binding glutamate-rich protein | -0.00713182 |
| FHIT | fragile histidine triad | -0.00712155 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00710137 |
| SERHL2 | serine hydrolase-like 2 | -0.00709275 |
| PON2 | paraoxonase 2 | -0.00708095 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.00701558 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | -0.00697432 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00691309 |
| TSPAN13 | tetraspanin 13 | -0.006911 |
| ETHE1 | ethylmalonic encephalopathy 1 | -0.00688469 |
| KRT23 | keratin 23, type I | -0.00687305 |
| TNNC2 | troponin C type 2 (fast) | -0.00686431 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | -0.00685155 |
| FOLR1 | folate receptor 1 (adult) | -0.0068238 |
| SCEL | sciellin | -0.00676814 |
| CLIC5 | chloride intracellular channel 5 | -0.0067665 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | -0.00675831 |
| PADI2 | peptidyl arginine deiminase, type II | -0.00675243 |
| TTN | titin | -0.00673915 |
| COX7A2L | cytochrome c oxidase subunit VIIa polypeptide 2 like | -0.00673361 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00673306 |
| MSMB | microseminoprotein, beta- | -0.00670844 |
| HOMER1 | homer scaffolding protein 1 | -0.00670566 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | -0.00670436 |
| IFI44 | interferon-induced protein 44 | -0.0066536 |
| KRT18 | keratin 18, type I | -0.0066335 |
| S100A7 | S100 calcium binding protein A7 | -0.00662226 |
| ZMAT3 | zinc finger, matrin-type 3 | -0.00660552 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00659411 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00657625 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.0065403 |
| ANXA3 | annexin A3 | -0.00653286 |
| CLIC3 | chloride intracellular channel 3 | -0.00652587 |
| VPREB1 | pre-B lymphocyte 1 | -0.00651553 |
| STK38L | serine/threonine kinase 38 like | -0.00651513 |
| IFI44L | interferon-induced protein 44-like | -0.00650701 |
| ANXA11 | annexin A11 | -0.00649396 |
| PDE8B | phosphodiesterase 8B | -0.00647601 |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | -0.00644634 |
| MX1 | MX dynamin-like GTPase 1 | -0.00644386 |
| IL2RG | interleukin 2 receptor, gamma | -0.00642624 |
| MYOT | myotilin | -0.00641773 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -0.00640573 |
| OPTN | optineurin | -0.00639952 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | -0.00639396 |
| BUD31 | BUD31 homolog (S. cerevisiae) | -0.00639004 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00638805 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.00638422 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.00638225 |
| GRN | granulin | -0.00634597 |
| REEP5 | receptor accessory protein 5 | -0.00634593 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00634389 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | -0.00633998 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.00631116 |
| IL32 | interleukin 32 | -0.00628465 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | -0.00628116 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00627269 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00627097 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.00626443 |
| MYOZ2 | myozenin 2 | -0.00625628 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.00624919 |
| C6ORF48 | chromosome 6 open reading frame 48 | -0.00620741 |
| TP53TG1 | TP53 target 1 (non-protein coding) | -0.00619337 |
| TAC1 | tachykinin, precursor 1 | -0.00619258 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | -0.00618504 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.00615426 |
| IFI35 | interferon-induced protein 35 | -0.00614169 |
| MLF1 | myeloid leukemia factor 1 | -0.00613846 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0061149 |
| GPR65 | G protein-coupled receptor 65 | -0.00610957 |
| OGN | osteoglycin | -0.0060858 |
| TEAD4 | TEA domain family member 4 | -0.00608268 |
| SMPX | small muscle protein, X-linked | -0.00607898 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | -0.00607128 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | -0.00605678 |
| ACP5 | acid phosphatase 5, tartrate resistant | -0.00599806 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | -0.00598175 |
| FOSL2 | FOS-like antigen 2 | -0.00597995 |
| RAB9A | RAB9A, member RAS oncogene family | -0.00596421 |
| MXRA7 | matrix-remodelling associated 7 | -0.00595832 |
| TRIM16 | tripartite motif containing 16 | -0.00593955 |
| C5AR1 | complement component 5a receptor 1 | -0.00593949 |
| HIST1H2AC | histone cluster 1, H2ac | -0.00593264 |
| GGT1 | gamma-glutamyltransferase 1 | -0.00592789 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.00592149 |
| FOXG1 | forkhead box G1 | -0.00592124 |
| E2F2 | E2F transcription factor 2 | -0.00591233 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -0.00590494 |
| C8ORF4 | chromosome 8 open reading frame 4 | -0.00590238 |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | -0.00587253 |
| CLEC2D | C-type lectin domain family 2, member D | -0.0058653 |
| ZNF394 | zinc finger protein 394 | -0.00586401 |
| MT2A | metallothionein 2A | -0.00585419 |
| FOXO1 | forkhead box O1 | -0.00585224 |
| HIST1H2BD | histone cluster 1, H2bd | -0.00584932 |
| RPP40 | ribonuclease P/MRP 40kDa subunit | -0.00582293 |
| MT1F | metallothionein 1F | -0.00580824 |
| STON1 | stonin 1 | -0.00579936 |
| IFRD1 | interferon-related developmental regulator 1 | -0.00579787 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.00579776 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | -0.00579606 |
| ZNF593 | zinc finger protein 593 | -0.00578636 |
| CKMT2 | creatine kinase, mitochondrial 2 (sarcomeric) | -0.00577246 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | -0.00577175 |
| QPRT | quinolinate phosphoribosyltransferase | -0.00576943 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 | -0.00576283 |
| PERP | PERP, TP53 apoptosis effector | -0.00575741 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00574959 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.00572153 |
| GSTP1 | glutathione S-transferase pi 1 | -0.00572012 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | -0.00570423 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.0056871 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.00568357 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.00568028 |
| CLDN8 | claudin 8 | -0.0056775 |
| CAPN3 | calpain 3, (p94) | -0.0056769 |
| RHOC | ras homolog family member C | -0.00567123 |
| C1S | complement component 1, s subcomponent | -0.00566714 |
| ARPP21 | cAMP-regulated phosphoprotein, 21kDa | -0.00566218 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | -0.00566021 |
| RRAGD | Ras-related GTP binding D | -0.00565583 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | -0.005648 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 | -0.00564723 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent | -0.00563748 |
| UXT | ubiquitously-expressed, prefoldin-like chaperone | -0.00563406 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.00563119 |
| LDB3 | LIM domain binding 3 | -0.00562553 |
| HEXB | hexosaminidase B (beta polypeptide) | -0.00562546 |
| BIN1 | bridging integrator 1 | -0.00562189 |
| AAGAB | alpha- and gamma-adaptin binding protein | -0.00560495 |
| FBXO11 | F-box protein 11 | -0.00559203 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | -0.00557041 |
| MOSPD1 | motile sperm domain containing 1 | -0.00556112 |
| FNTA | farnesyltransferase, CAAX box, alpha | -0.00555726 |
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 | -0.00554893 |
| XIC | X chromosome inactivation center | -0.00554669 |
| LUM | lumican | -0.00554206 |
| HBD | hemoglobin, delta | -0.00552799 |
| H1-2 | H1.2 linker histone, cluster member | -0.00552723 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | -0.00552573 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -0.00552205 |
| RGS1 | regulator of G-protein signaling 1 | -0.00552069 |
| FKBP11 | FK506 binding protein 11, 19 kDa | -0.00552028 |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | -0.00551564 |
| CSRP2 | cysteine and glycine-rich protein 2 | -0.00551108 |
