APH1B Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description APH1B gamma secretase subunit|This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein. [provided by RefSeq, Sep 2011] (NCBI Entrez Gene Database, 83464)
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Genes

389 genes differentially expressed following the APH1B gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
XKRX XK, Kell blood group complex subunit-related, X-linked 2.89442
CCR10 chemokine (C-C motif) receptor 10 2.89442
SLC7A14 solute carrier family 7, member 14 2.89442
CELA2B chymotrypsin-like elastase family, member 2B 2.89442
TSPAN8 tetraspanin 8 2.89442
TSSK6 testis-specific serine kinase 6 2.89442
CSRNP1 cysteine-serine-rich nuclear protein 1 2.89442
PADI3 peptidyl arginine deiminase, type III 2.89442
EVPLL envoplakin-like 2.89442
AHNAK2 AHNAK nucleoprotein 2 2.89442
RABGGTA Rab geranylgeranyltransferase, alpha subunit 2.89442
CARMIL2 capping protein regulator and myosin 1 linker 2 2.89442
PPP2R5B protein phosphatase 2, regulatory subunit B', beta 2.89442
SLC10A4 solute carrier family 10, member 4 2.89442
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 2.89442
LXN latexin 2.89442
NPM2 nucleophosmin/nucleoplasmin 2 2.89442
VENTX VENT homeobox 2.89442
CLEC2L C-type lectin domain family 2, member L 2.89442
FCRL5 Fc receptor-like 5 2.89442
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 2.89442
PABPC5 poly(A) binding protein, cytoplasmic 5 2.89442
MEIS2 Meis homeobox 2 2.89442
MIXL1 Mix paired-like homeobox 2.89442
EXD1 exonuclease 3'-5' domain containing 1 2.89442
GPR26 G protein-coupled receptor 26 2.79192
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) 2.79192
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 2.79192
FIMP1 fertilization-influencing membrane protein 1 2.79192
MUC6 mucin 6, oligomeric mucus/gel-forming 2.79192
TMEM240 transmembrane protein 240 2.79192
PLXDC1 plexin domain containing 1 2.79192
PDZD7 PDZ domain containing 7 2.79192
SLC25A45 solute carrier family 25, member 45 2.79192
TNC tenascin C 2.79192
CXORF65 chromosome X open reading frame 65 2.79192
TMEM100 transmembrane protein 100 2.79192
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 2.79192
C6ORF58 chromosome 6 open reading frame 58 2.79192
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13 2.79192
ZNF233 zinc finger protein 233 2.79192
TRIM72 tripartite motif containing 72, E3 ubiquitin protein ligase 2.79192
SIM1 single-minded family bHLH transcription factor 1 2.79192
TTC6 tetratricopeptide repeat domain 6 2.79192
VN1R1 vomeronasal 1 receptor 1 2.79192
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 2.79192
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 2.79192
PNLIPRP2 pancreatic lipase-related protein 2 2.79192
PCDHGA11 protocadherin gamma subfamily A, 11 2.79192
ZNF528 zinc finger protein 528 2.79192
HTRA3 HtrA serine peptidase 3 2.79192
HYPK huntingtin interacting protein K 2.79192
FRG2C FSHD region gene 2 family, member C 2.79192
STRA8 stimulated by retinoic acid 8 2.79192
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 2.79192
MGARP mitochondria-localized glutamic acid-rich protein 2.79192
DNAAF1 dynein, axonemal, assembly factor 1 2.79192
RHCE Rh blood group, CcEe antigens 2.79192
SHD Src homology 2 domain containing transforming protein D 2.79192
FOXJ1 forkhead box J1 2.79192
C2ORF72 chromosome 2 open reading frame 72 2.79192
CELF6 CUGBP, Elav-like family member 6 2.79192
FAM107A family with sequence similarity 107, member A 2.79192
SCRT2 scratch family zinc finger 2 2.79192
TRPA1 transient receptor potential cation channel, subfamily A, member 1 2.79192
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 2.79192
RBMX2 RNA binding motif protein, X-linked 2 2.79192
HEMK1 HemK methyltransferase family member 1 2.79192
SLC22A25 solute carrier family 22, member 25 2.79192
COL6A6 collagen, type VI, alpha 6 2.79192
C3ORF80 chromosome 3 open reading frame 80 2.79192
ZSWIM2 zinc finger, SWIM-type containing 2 2.79192
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 2.79192
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 2.79192
HBQ1 hemoglobin, theta 1 2.79192
LTB lymphotoxin beta (TNF superfamily, member 3) 2.79192
ACE2 angiotensin I converting enzyme 2 2.79192
DNAL4 dynein, axonemal, light chain 4 2.79192
FAM131C family with sequence similarity 131, member C 2.79192
SAMD11 sterile alpha motif domain containing 11 2.79192
C3 complement component 3 2.79192
CLDN23 claudin 23 2.79192
EGF epidermal growth factor 2.79192
PARVG parvin, gamma 2.79192
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 2.79192
F5 coagulation factor V (proaccelerin, labile factor) 2.79192
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 2.79192
ELF4 E74-like factor 4 (ets domain transcription factor) 2.79192
LURAP1L leucine rich adaptor protein 1-like 2.79192
JOSD2 Josephin domain containing 2 2.79192
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 2.79192
DNAJC5G DnaJ (Hsp40) homolog, subfamily C, member 5 gamma 2.79192
MAP3K7CL MAP3K7 C-terminal like 2.79192
DOK3 docking protein 3 2.79192
TMPRSS7 transmembrane protease, serine 7 2.79192
SCN2A sodium channel, voltage gated, type II alpha subunit 2.79192
LRRTM2 leucine rich repeat transmembrane neuronal 2 2.79192
C19ORF73 chromosome 19 open reading frame 73 2.79192
CFL1 cofilin 1 (non-muscle) 2.79192
VSIG1 V-set and immunoglobulin domain containing 1 2.79192
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 2.79192
SLFN14 schlafen family member 14 2.79192
SPATC1 spermatogenesis and centriole associated 1 2.79192
ACTL8 actin-like 8 2.79192
DPF3 D4, zinc and double PHD fingers, family 3 2.79192
FRMD7 FERM domain containing 7 2.79192
TBX20 T-box 20 2.79192
SBK2 SH3 domain binding kinase family, member 2 2.79192
RAB36 RAB36, member RAS oncogene family 2.79192
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 2.79192
RPUSD3 RNA pseudouridylate synthase domain containing 3 2.79192
KRT17 keratin 17, type I 2.79192
GPR12 G protein-coupled receptor 12 2.79192
SV2C synaptic vesicle glycoprotein 2C 2.79192
GRK7 G protein-coupled receptor kinase 7 2.79192
NUTM1 NUT midline carcinoma, family member 1 2.79192
CPSF4L cleavage and polyadenylation specific factor 4-like 2.79192
FAAP100 FA core complex associated protein 100 2.79192
VEGFD vascular endothelial growth factor D 2.79192
ADAM8 ADAM metallopeptidase domain 8 2.79192
PLET1 placenta expressed transcript 1 2.79192
C1QTNF12 C1q and TNF related 12 2.79192
POF1B premature ovarian failure, 1B 2.79192
AMIGO1 adhesion molecule with Ig-like domain 1 2.79192
CASS4 Cas scaffolding protein family member 4 2.79192
OR9Q1 olfactory receptor, family 9, subfamily Q, member 1 2.79192
BMX BMX non-receptor tyrosine kinase 2.79192
DACT3 dishevelled-binding antagonist of beta-catenin 3 2.79192
CTF1 cardiotrophin 1 2.79192
GLYATL3 glycine-N-acyltransferase-like 3 2.79192
RHPN1 rhophilin, Rho GTPase binding protein 1 2.79192
MR1 major histocompatibility complex, class I-related 2.79192
CLDN34 claudin 34 2.79192
CDC20B cell division cycle 20B 2.79192
SLC47A2 solute carrier family 47 (multidrug and toxin extrusion), member 2 2.79192
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 2.79192
IGSF10 immunoglobulin superfamily, member 10 2.79192
POU2AF1 POU class 2 associating factor 1 2.79192
ERFE erythroferrone 2.79192
WIF1 WNT inhibitory factor 1 2.79192
MEIOSIN meiosis initiator 2.79192
RIN1 Ras and Rab interactor 1 2.79192
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 2.79192
GBX1 gastrulation brain homeobox 1 2.79192
CLEC18B C-type lectin domain family 18, member B 2.79192
GOLGA8M golgin A8 family, member M 2.79192
CD28 CD28 molecule 2.79192
CTSO cathepsin O 2.79192
ZFP28 ZFP28 zinc finger protein 2.79192
TMEM139 transmembrane protein 139 2.79192
CLSPN claspin 2.79192
SVOP SV2 related protein homolog (rat) 2.79192
COL9A2 collagen, type IX, alpha 2 2.79192
SCUBE2 signal peptide, CUB domain, EGF-like 2 2.79192
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 2.79192
SPHKAP SPHK1 interactor, AKAP domain containing 2.79192
NTN5 netrin 5 2.79192
VAV1 vav 1 guanine nucleotide exchange factor 2.79192
RIIAD1 regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1 2.79192
CD34 CD34 molecule 2.79192
DNAJB7 DnaJ (Hsp40) homolog, subfamily B, member 7 2.79192
SLX1A SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) 2.79192
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 2.79192
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2 2.79192
AGBL4 ATP/GTP binding protein-like 4 2.79192
LRRC31 leucine rich repeat containing 31 2.79192
ZNF296 zinc finger protein 296 2.79192
POTEF POTE ankyrin domain family, member F 2.79192
MMP19 matrix metallopeptidase 19 2.79192
ANXA8 annexin A8 2.79192
TMEM213 transmembrane protein 213 2.79192
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 2.79192
OTX1 orthodenticle homeobox 1 2.79192
GLB1L galactosidase, beta 1-like 2.79192
ZFP36 ZFP36 ring finger protein 2.79192
KIF12 kinesin family member 12 2.79192
GGN gametogenetin 2.79192
TRMT10C tRNA methyltransferase 10 homolog C (S. cerevisiae) 2.79192
STOML3 stomatin (EPB72)-like 3 2.79192
LINGO3 leucine rich repeat and Ig domain containing 3 2.79192
TANK TRAF family member-associated NFKB activator 2.79192
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 2.79192
WDR72 WD repeat domain 72 2.79192
TULP1 tubby like protein 1 2.79192
ANKRD62 ankyrin repeat domain 62 2.79192
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28 2.79192
FOSB FBJ murine osteosarcoma viral oncogene homolog B 2.79192
FCN3 ficolin (collagen/fibrinogen domain containing) 3 2.79192
PLA2G4D phospholipase A2, group IVD (cytosolic) 2.79192
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 2.79192
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 2.79192
NUTM2G NUT family member 2G 2.79192
RASL12 RAS-like, family 12 2.79192
PAK5 p21 (RAC1) activated kinase 5 2.75191
DENND2C DENN/MADD domain containing 2C 2.73921
RIDA reactive intermediate imine deaminase A homolog 2.69589
ZFYVE28 zinc finger, FYVE domain containing 28 2.69583
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2 2.69411
EHD2 EH-domain containing 2 2.67377
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 2.67295
CAV2 caveolin 2 2.64756
SLC25A30 solute carrier family 25, member 30 2.64756
FKBPL FK506 binding protein like 2.64756
SACK1G scaffolding CK1 anchoring protein G 2.64756
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 2.64756
KIF26A kinesin family member 26A 2.64756
GSPT2 G1 to S phase transition 2 2.64756
ENDOD1 endonuclease domain containing 1 2.64756
RDH10 retinol dehydrogenase 10 (all-trans) 2.64756
COX6C cytochrome c oxidase subunit VIc 2.64756
CDK15 cyclin-dependent kinase 15 2.64756
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6 2.62348
BAG5 BCL2-associated athanogene 5 2.59956
GTPBP8 GTP-binding protein 8 (putative) 2.58824
PTCHD4 patched domain containing 4 2.58824
SAFB scaffold attachment factor B 2.58503
DGKZ diacylglycerol kinase, zeta 2.57398
UBE2J1 ubiquitin-conjugating enzyme E2, J1 2.57356
MZF1 myeloid zinc finger 1 2.53599
UBL5 ubiquitin-like 5 2.53023
SLC35E1 solute carrier family 35, member E1 2.52489
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 2.51311
GPNMB glycoprotein (transmembrane) nmb 2.51311
IL17RB interleukin 17 receptor B 2.49321
LRTM1 leucine-rich repeats and transmembrane domains 1 2.49321
CAMK4 calcium/calmodulin-dependent protein kinase IV 2.46185
RAB8A RAB8A, member RAS oncogene family 2.45949
PPP6R2 protein phosphatase 6, regulatory subunit 2 2.42149
ETFB electron-transfer-flavoprotein, beta polypeptide 2.41289
UHMK1 U2AF homology motif (UHM) kinase 1 2.40968
BBS10 Bardet-Biedl syndrome 10 2.40291
LYPD6 LY6/PLAUR domain containing 6 2.38916
ANKAR ankyrin and armadillo repeat containing 2.37495
TMEM216 transmembrane protein 216 2.36021
TMEM254 transmembrane protein 254 2.34861
VIM vimentin 2.34271
THAP9 THAP domain containing 9 2.31841
MLF2 myeloid leukemia factor 2 2.24118
ATL1 atlastin GTPase 1 2.207
MARK3 MAP/microtubule affinity-regulating kinase 3 2.19426
PHF21B PHD finger protein 21B 2.18659
SLCO6A1 solute carrier organic anion transporter family, member 6A1 2.1539
TINF2 TERF1 (TRF1)-interacting nuclear factor 2 2.14094
FAM234A family with sequence similarity 234 member A 2.13994
SDF2L1 stromal cell-derived factor 2-like 1 2.12837
TMEM167A transmembrane protein 167A 2.1095
FAM216A family with sequence similarity 216, member A 2.1095
NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) 2.08824
YJU2B YJU2 splicing factor homolog B 2.08468
ISCU iron-sulfur cluster assembly enzyme 2.05573
C14ORF132 chromosome 14 open reading frame 132 2.04976
GANC glucosidase, alpha; neutral C 2.04086
KRT10 keratin 10, type I 2.03428
CDK14 cyclin-dependent kinase 14 2.02396
TIGD2 tigger transposable element derived 2 2.01297
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa 2.01297
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 2.01068
TBC1D16 TBC1 domain family, member 16 2.00566
GCA grancalcin, EF-hand calcium binding protein 2.00566

decreased expression

Symbol Name Standardized Value
L3HYPDH L-3-hydroxyproline dehydratase (trans-) -2.89442
GSTM4 glutathione S-transferase mu 4 -2.89442
FHAD1 forkhead-associated (FHA) phosphopeptide binding domain 1 -2.89442
SH3BGRL2 SH3 domain binding glutamate-rich protein like 2 -2.89442
PSTK phosphoseryl-tRNA kinase -2.89442
FAM8A1 family with sequence similarity 8, member A1 -2.89442
SLC13A4 solute carrier family 13 (sodium/sulfate symporter), member 4 -2.89442
ACOX3 acyl-CoA oxidase 3, pristanoyl -2.89442
FBXO44 F-box protein 44 -2.79192
ZC2HC1C zinc finger, C2HC-type containing 1C -2.79192
AIF1 allograft inflammatory factor 1 -2.79192
CCSER2 coiled-coil serine-rich protein 2 -2.79192
BAIAP2 BAI1-associated protein 2 -2.79192
PPP1R1C protein phosphatase 1, regulatory (inhibitor) subunit 1C -2.79192
POT1 protection of telomeres 1 -2.79192
NOSTRIN nitric oxide synthase trafficking -2.79192
RAB37 RAB37, member RAS oncogene family -2.79192
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 -2.79192
SELENBP1 selenium binding protein 1 -2.79192
PACSIN1 protein kinase C and casein kinase substrate in neurons 1 -2.79192
FMO4 flavin containing monooxygenase 4 -2.79192
SEPTIN5 septin 5 -2.79192
LRMDA leucine rich melanocyte differentiation associated -2.79192
RAB39B RAB39B, member RAS oncogene family -2.78342
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit -2.77964
ARHGAP29 Rho GTPase activating protein 29 -2.7624
GMEB2 glucocorticoid modulatory element binding protein 2 -2.7595
EML3 echinoderm microtubule associated protein like 3 -2.64756
SPNS2 spinster homolog 2 (Drosophila) -2.64756
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -2.64756
EPHX4 epoxide hydrolase 4 -2.64756
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3 -2.64756
ATP8B3 ATPase, aminophospholipid transporter, class I, type 8B, member 3 -2.64756
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3 -2.64756
NME5 NME/NM23 family member 5 -2.64756
ZNF324 zinc finger protein 324 -2.64756
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -2.64756
H4C4 H4 clustered histone 4 -2.64756
ZEB2 zinc finger E-box binding homeobox 2 -2.64756
ADGRE2 adhesion G protein-coupled receptor E2 -2.64756
FAM13C family with sequence similarity 13, member C -2.64756
ZNF527 zinc finger protein 527 -2.64756
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 -2.64756
ENKUR enkurin, TRPC channel interacting protein -2.64756
CFAP90 cilia and flagella associated protein 90 -2.64756
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 -2.64756
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 -2.64756
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide -2.64756
ICOSLG inducible T-cell co-stimulator ligand -2.64756
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic -2.64756
APC2 adenomatosis polyposis coli 2 -2.64756
DNAI1 dynein, axonemal, intermediate chain 1 -2.64756
ACTRT3 actin-related protein T3 -2.64756
LDHD lactate dehydrogenase D -2.64756
SOX7 SRY (sex determining region Y)-box 7 -2.64756
OGDHL oxoglutarate dehydrogenase-like -2.64756
FAAH fatty acid amide hydrolase -2.64756
UPK1A uroplakin 1A -2.64756
ZNF628 zinc finger protein 628 -2.64756
KLC3 kinesin light chain 3 -2.64756
GNG7 guanine nucleotide binding protein (G protein), gamma 7 -2.64756
ASXL3 additional sex combs like transcriptional regulator 3 -2.64756
KANK4 KN motif and ankyrin repeat domains 4 -2.64756
BHMT betaine--homocysteine S-methyltransferase -2.64756
FSTL5 follistatin-like 5 -2.64756
FRMPD3 FERM and PDZ domain containing 3 -2.64756
GEM GTP binding protein overexpressed in skeletal muscle -2.64756
ETNPPL ethanolamine-phosphate phospho-lyase -2.64756
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain -2.64756
ZNF165 zinc finger protein 165 -2.64756
SLC2A12 solute carrier family 2 (facilitated glucose transporter), member 12 -2.64641
MMP9 matrix metallopeptidase 9 -2.62175
CGRRF1 cell growth regulator with ring finger domain 1 -2.57575
RPAIN RPA interacting protein -2.5432
HS6ST1 heparan sulfate 6-O-sulfotransferase 1 -2.49321
U2AF1L4 U2 small nuclear RNA auxiliary factor 1-like 4 -2.48646
GALNT4 polypeptide N-acetylgalactosaminyltransferase 4 -2.48646
YPEL2 yippee-like 2 (Drosophila) -2.48646
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 -2.4713
PRXL2C peroxiredoxin like 2C -2.4713
CHMP3 charged multivesicular body protein 3 -2.45243
HHIP hedgehog interacting protein -2.42387
GORASP1 golgi reassembly stacking protein 1, 65kDa -2.42387
ZNF667 zinc finger protein 667 -2.40291
RPA1 replication protein A1, 70kDa -2.3669
LRRC1 leucine rich repeat containing 1 -2.31841
RAB3C RAB3C, member RAS oncogene family -2.27366
TNNT2 troponin T type 2 (cardiac) -2.26717
STAG1 stromal antigen 1 -2.26124
SACK1B scaffolding CK1 anchoring protein B -2.25236
PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3 -2.251
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.25042
TEN1 TEN1 CST complex subunit -2.24549
ATP7B ATPase, Cu++ transporting, beta polypeptide -2.22989
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -2.22989
MINDY3 MINDY lysine 48 deubiquitinase 3 -2.22989
PHYHD1 phytanoyl-CoA dioxygenase domain containing 1 -2.22356
MRPL51 mitochondrial ribosomal protein L51 -2.22356
MSANTD3 Myb/SANT-like DNA-binding domain containing 3 -2.22356
WAC WW domain containing adaptor with coiled-coil -2.207
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase -2.19426
NMD3 NMD3 ribosome export adaptor -2.1901
ELL elongation factor RNA polymerase II -2.19001
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F -2.19001
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 -2.18477
LRRC41 leucine rich repeat containing 41 -2.18356
TTI1 TELO2 interacting protein 1 -2.16752
R3HDM2 R3H domain containing 2 -2.16752
ANO8 anoctamin 8 -2.16751
RAB39A RAB39A, member RAS oncogene family -2.16629
TUBE1 tubulin, epsilon 1 -2.15075
ZNF223 zinc finger protein 223 -2.12837
STRA6 stimulated by retinoic acid 6 -2.12837
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -2.12659
CLIC4 chloride intracellular channel 4 -2.06659
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa -2.04361
ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 -2.02895
FGF11 fibroblast growth factor 11 -2.02895
MLKL mixed lineage kinase domain-like -2.02895
ISM1 isthmin 1, angiogenesis inhibitor -2.02895
ESYT3 extended synaptotagmin-like protein 3 -2.02895
TMEM114 transmembrane protein 114 -2.02895
AP1G2 adaptor-related protein complex 1, gamma 2 subunit -2.02895
FIGNL1 fidgetin-like 1 -2.02895
OCA2 oculocutaneous albinism II -2.02895
FOXO3B forkhead box O3B pseudogene -2.02895
LYPD1 LY6/PLAUR domain containing 1 -2.02895
SLC16A13 solute carrier family 16, member 13 -2.02895
SIT1 signaling threshold regulating transmembrane adaptor 1 -2.02895
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase -2.01068