| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | APH1B gamma secretase subunit|This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein. [provided by RefSeq, Sep 2011] (NCBI Entrez Gene Database, 83464) |
| External Link | https://ncbi.nlm.nih.gov/gene/83464 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the APH1B gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| XIC | X chromosome inactivation center | 0.015173 |
| MEF2C | myocyte enhancer factor 2C | 0.0139759 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.0139676 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0118972 |
| TBX2 | T-box 2 | 0.0118017 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0117211 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0110912 |
| HOPX | HOP homeobox | 0.0105905 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0102551 |
| POU2AF1 | POU class 2 associating factor 1 | 0.0100511 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00999669 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.00965762 |
| TSPAN13 | tetraspanin 13 | 0.00960668 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.00935197 |
| CTSG | cathepsin G | 0.00929182 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00924441 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | 0.00906507 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.00902571 |
| ITGA6 | integrin, alpha 6 | 0.00902438 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.00892004 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00872406 |
| ECM1 | extracellular matrix protein 1 | 0.00868305 |
| SIK1 | salt-inducible kinase 1 | 0.00865434 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.00844073 |
| KRT23 | keratin 23, type I | 0.008433 |
| MAP7 | microtubule-associated protein 7 | 0.00835423 |
| KRT17 | keratin 17, type I | 0.00825706 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | 0.00820784 |
| ATF3 | activating transcription factor 3 | 0.00819907 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | 0.00814436 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.00803363 |
| DUSP5 | dual specificity phosphatase 5 | 0.00802219 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00802194 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.00800782 |
| OPHN1 | oligophrenin 1 | 0.00786327 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00775616 |
| TGFB1 | transforming growth factor, beta 1 | 0.00771695 |
| ZNF281 | zinc finger protein 281 | 0.00758429 |
| KLF6 | Kruppel-like factor 6 | 0.00747503 |
| BST2 | bone marrow stromal cell antigen 2 | 0.00741479 |
| FN1 | fibronectin 1 | 0.00741409 |
| CHP1 | calcineurin-like EF-hand protein 1 | 0.00741327 |
| CD19 | CD19 molecule | 0.00728934 |
| LOX | lysyl oxidase | 0.00725464 |
| FNDC3B | fibronectin type III domain containing 3B | 0.00723561 |
| BRD4 | bromodomain containing 4 | 0.00723507 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00720795 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.00720644 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.0071797 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.00716252 |
| CD34 | CD34 molecule | 0.00706282 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.00704908 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | 0.00699058 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.00691992 |
| MTA1 | metastasis associated 1 | 0.00683112 |
| ELANE | elastase, neutrophil expressed | 0.00677725 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.00676836 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 0.00675445 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00671675 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.00670277 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | 0.00669741 |
| CLDN4 | claudin 4 | 0.00669015 |
| LYPD1 | LY6/PLAUR domain containing 1 | 0.00668705 |
| AHCYL1 | adenosylhomocysteinase-like 1 | 0.00668419 |
| ACTN4 | actinin, alpha 4 | 0.00665882 |
| MICALL1 | MICAL-like 1 | 0.00664269 |
| S100A8 | S100 calcium binding protein A8 | 0.00660489 |
| JUP | junction plakoglobin | 0.00657098 |
| KLK5 | kallikrein-related peptidase 5 | 0.00655495 |
| SIRT3 | sirtuin 3 | 0.00654135 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0065214 |
| GNAS | GNAS complex locus | 0.00649454 |
| KRT16 | keratin 16, type I | 0.00648854 |
| DAPK1 | death-associated protein kinase 1 | 0.00648606 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00647888 |
| IRF1 | interferon regulatory factor 1 | 0.00646887 |
| SCARB2 | scavenger receptor class B, member 2 | 0.00645939 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0064524 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | 0.00644052 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.00639067 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.00636162 |
| CLC | Charcot-Leyden crystal galectin | 0.00635884 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.00635598 |
| IGSF3 | immunoglobulin superfamily, member 3 | 0.00633967 |
| MMP7 | matrix metallopeptidase 7 | 0.00632597 |
| HMOX1 | heme oxygenase 1 | 0.00628348 |
| S100A9 | S100 calcium binding protein A9 | 0.00626716 |
| HDDC2 | HD domain containing 2 | 0.00625211 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.00620101 |
| STAB1 | stabilin 1 | 0.0061982 |
| RGS1 | regulator of G-protein signaling 1 | 0.00618919 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | 0.00615255 |
| CD200 | CD200 molecule | 0.00610773 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.00610627 |
| CIDEC | cell death-inducing DFFA-like effector c | 0.00608279 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.00607075 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00606184 |
| CDC42 | cell division cycle 42 | 0.00601912 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.00600766 |
| ADM | adrenomedullin | 0.00599603 |
| BTG3 | BTG family, member 3 | 0.00595605 |
| CDA | cytidine deaminase | 0.00594856 |
| IL1RN | interleukin 1 receptor antagonist | 0.00591806 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.00590743 |
| HLA-B | major histocompatibility complex, class I, B | 0.0058965 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.00589254 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00585132 |
| GPX3 | glutathione peroxidase 3 | 0.00584476 |
| RETREG1 | reticulophagy regulator 1 | 0.00584266 |
| PTCH1 | patched 1 | 0.00584109 |
| KRT18 | keratin 18, type I | 0.00582396 |
| KLF9 | Kruppel-like factor 9 | 0.00580562 |
| PAX5 | paired box 5 | 0.00579221 |
| SETD5 | SET domain containing 5 | 0.00579204 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.00578957 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.005788 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00577359 |
| KLK10 | kallikrein-related peptidase 10 | 0.00574864 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.00574549 |
| PPL | periplakin | 0.00573737 |
| AIM2 | absent in melanoma 2 | 0.00571015 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.0057068 |
| CD163 | CD163 molecule | 0.00569746 |
| HSPB1 | heat shock 27kDa protein 1 | 0.00569693 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.00569319 |
| CD69 | CD69 molecule | 0.0056649 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00566255 |
| HELZ | helicase with zinc finger | 0.00565683 |
| GRAMD2B | GRAM domain containing 2B | 0.00564872 |
| ZNF91 | zinc finger protein 91 | 0.00563161 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 0.00562735 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.00562009 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | 0.0056189 |
| U2AF1 | U2 small nuclear RNA auxiliary factor 1 | 0.00559435 |
| MERTK | MER proto-oncogene, tyrosine kinase | 0.00559036 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00558036 |
| BCL2A1 | BCL2-related protein A1 | 0.00556311 |
| PMM2 | phosphomannomutase 2 | 0.00556284 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | 0.00555487 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.00554921 |
| CNTN1 | contactin 1 | 0.00550716 |
| EGR1 | early growth response 1 | 0.00550643 |
| TCF4 | transcription factor 4 | 0.00549502 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.00549089 |
| MMP9 | matrix metallopeptidase 9 | 0.00548803 |
| CLU | clusterin | 0.00548335 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.00547537 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.00546975 |
| LSM7 | LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00545375 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.00545279 |
| PMP22 | peripheral myelin protein 22 | 0.00544432 |
| NXN | nucleoredoxin | 0.00543753 |
| ZNF117 | zinc finger protein 117 | 0.00543161 |
| STC2 | stanniocalcin 2 | 0.00541619 |
| KRT81 | keratin 81, type II | 0.00540672 |
| UPK1B | uroplakin 1B | 0.00540609 |
| PRKCB | protein kinase C, beta | 0.00540583 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | 0.00540047 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00539788 |
| CD79B | CD79b molecule, immunoglobulin-associated beta | 0.00539579 |
| JUNB | jun B proto-oncogene | 0.0053706 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.00536718 |
| TMPRSS11E | transmembrane protease, serine 11E | 0.00536102 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.00535839 |
| ACTN1 | actinin, alpha 1 | 0.00535627 |
| RNASE3 | ribonuclease, RNase A family, 3 | 0.00535116 |
| FABP7 | fatty acid binding protein 7, brain | 0.00534531 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00532215 |
| CD58 | CD58 molecule | 0.0053121 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 0.0052983 |
| SPRR1B | small proline-rich protein 1B | 0.00529395 |
| S100A12 | S100 calcium binding protein A12 | 0.00528185 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | 0.00528084 |
| TNS3 | tensin 3 | 0.00527933 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.00526594 |
| EZR | ezrin | 0.00525728 |
| CKM | creatine kinase, muscle | 0.00525449 |
| C21ORF91 | chromosome 21 open reading frame 91 | 0.00525017 |
| IER2 | immediate early response 2 | 0.00524167 |
| CRYAB | crystallin, alpha B | 0.00523859 |
| CYB5R2 | cytochrome b5 reductase 2 | 0.00523439 |
| PLIN1 | perilipin 1 | 0.00523264 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.0052315 |
| ABHD4 | abhydrolase domain containing 4 | 0.00519377 |
| DNM1L | dynamin 1-like | 0.00518473 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | 0.00516987 |
| CLEC2B | C-type lectin domain family 2, member B | 0.00516076 |
| USP47 | ubiquitin specific peptidase 47 | 0.00515938 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.00512828 |
| IVL | involucrin | 0.00512711 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00511562 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.00510776 |
| ITGA7 | integrin, alpha 7 | 0.00509355 |
| TYMS | thymidylate synthetase | 0.00509326 |
| ELOB | elongin B | 0.00508667 |
| ARPC5L | actin related protein 2/3 complex, subunit 5-like | 0.00508456 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.00507492 |
| KAZN | kazrin, periplakin interacting protein | 0.00506296 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.00505826 |
| CMTM6 | CKLF-like MARVEL transmembrane domain containing 6 | 0.00502909 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00501934 |
| THOC2 | THO complex 2 | 0.00501649 |
| MGAT4B | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B | 0.00500655 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.00498848 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | 0.00498826 |
| ARHGAP25 | Rho GTPase activating protein 25 | 0.00498803 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.00498762 |
| CDC34 | cell division cycle 34 | 0.00497196 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00496964 |
| DOCK9 | dedicator of cytokinesis 9 | 0.00496695 |
| GLTP | glycolipid transfer protein | 0.00496095 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00495096 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00495078 |
| EFNB2 | ephrin-B2 | 0.00493269 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.0049295 |
| LAMB3 | laminin, beta 3 | 0.00492837 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.00492696 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00492416 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.00492226 |
| LBH | limb bud and heart development | 0.00490794 |
| WT1 | Wilms tumor 1 | 0.00490423 |
| MSL1 | male-specific lethal 1 homolog (Drosophila) | 0.00490221 |
| OLFML2A | olfactomedin-like 2A | 0.00489176 |
| PCDH9 | protocadherin 9 | 0.00487317 |
| CANX | calnexin | 0.00486271 |
| MTCL1 | microtubule crosslinking factor 1 | 0.00486056 |
| SLBP | stem-loop binding protein | 0.00486006 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00485674 |
| ELP1 | elongator acetyltransferase complex subunit 1 | 0.00485094 |
| BTN2A1 | butyrophilin, subfamily 2, member A1 | 0.00483356 |
| ATOX1 | antioxidant 1 copper chaperone | 0.00482788 |
| MPHOSPH8 | M-phase phosphoprotein 8 | 0.00480494 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase | 0.00480013 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.00479963 |
| CAVIN1 | caveolae associated protein 1 | 0.00479217 |
| WDR45B | WD repeat domain 45B | 0.00477733 |
| SCPEP1 | serine carboxypeptidase 1 | 0.00477287 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 | 0.00476711 |
| SOWAHC | sosondowah ankyrin repeat domain family member C | 0.00476684 |
| S100P | S100 calcium binding protein P | 0.004759 |
| ROPN1B | rhophilin associated tail protein 1B | 0.00475676 |
| CELP | carboxyl ester lipase pseudogene | 0.00475283 |
| ZNF611 | zinc finger protein 611 | 0.0047504 |
| PNN | pinin, desmosome associated protein | 0.00473443 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0047192 |
| PDLIM3 | PDZ and LIM domain 3 | 0.00471207 |
| AGPAT2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 | 0.00471009 |
| HLA-E | major histocompatibility complex, class I, E | 0.00469203 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.00468843 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 0.00468799 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0206105 |
| AOC1 | amine oxidase, copper containing 1 | -0.0170808 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -0.0169005 |
| ADI1 | acireductone dioxygenase 1 | -0.01453 |
| TMEM176B | transmembrane protein 176B | -0.0140773 |
| TMEM176A | transmembrane protein 176A | -0.0138626 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0123055 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | -0.0112893 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.0112568 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0111091 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.0107193 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.0104733 |
| AOX1 | aldehyde oxidase 1 | -0.0104445 |
| OLFM4 | olfactomedin 4 | -0.00981202 |
| NPTX2 | neuronal pentraxin II | -0.00964404 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | -0.00963241 |
| TFF1 | trefoil factor 1 | -0.00943007 |
| LEFTY1 | left-right determination factor 1 | -0.00942963 |
| CCNB1 | cyclin B1 | -0.009242 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.0091667 |
| CD1E | CD1e molecule | -0.00904982 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | -0.00895724 |
| FZD2 | frizzled class receptor 2 | -0.0084703 |
| GCA | grancalcin, EF-hand calcium binding protein | -0.00846675 |
| ASS1 | argininosuccinate synthase 1 | -0.00840059 |
| NMU | neuromedin U | -0.00819615 |
| HOXC10 | homeobox C10 | -0.00813076 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | -0.0080534 |
| ZIC1 | Zic family member 1 | -0.0078697 |
| AGTR1 | angiotensin II receptor, type 1 | -0.00783922 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.00779781 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00777536 |
| CD1B | CD1b molecule | -0.00773551 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00769747 |
| CD302 | CD302 molecule | -0.0076709 |
| PBK | PDZ binding kinase | -0.00764626 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | -0.00750375 |
| FBP1 | fructose-1,6-bisphosphatase 1 | -0.00748885 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | -0.00746737 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.00731188 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00726362 |
| YEATS4 | YEATS domain containing 4 | -0.00719513 |
| HSPA2 | heat shock 70kDa protein 2 | -0.0071826 |
| ALDOB | aldolase B, fructose-bisphosphate | -0.00714662 |
| SUMO3 | small ubiquitin-like modifier 3 | -0.007118 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | -0.00706695 |
| NEBL | nebulette | -0.0070047 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 | -0.00697809 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | -0.00693588 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00693476 |
| ACAT1 | acetyl-CoA acetyltransferase 1 | -0.0068542 |
| CHN2 | chimerin 2 | -0.00684074 |
| MT1E | metallothionein 1E | -0.00681913 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | -0.00681219 |
| NEFH | neurofilament, heavy polypeptide | -0.00680385 |
| BEX1 | brain expressed, X-linked 1 | -0.00671765 |
| ECI2 | enoyl-CoA delta isomerase 2 | -0.0066898 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.00668336 |
| CLEC4A | C-type lectin domain family 4, member A | -0.00662175 |
| EMP2 | epithelial membrane protein 2 | -0.00661349 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | -0.00659864 |
| FABP1 | fatty acid binding protein 1, liver | -0.00658888 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.00654143 |
| ESD | esterase D | -0.00650853 |
| PTPRO | protein tyrosine phosphatase, receptor type, O | -0.00650546 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.00650378 |
| ACP3 | acid phosphatase 3 | -0.00644783 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.00644073 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.00641335 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | -0.00639217 |
| NUP107 | nucleoporin 107kDa | -0.00638309 |
| SQLE | squalene epoxidase | -0.00636571 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | -0.00635298 |
| FGL2 | fibrinogen-like 2 | -0.00634854 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0063323 |
| MMP12 | matrix metallopeptidase 12 | -0.00628858 |
| TUBB2B | tubulin, beta 2B class IIb | -0.00626019 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.00623826 |
| MAOA | monoamine oxidase A | -0.00614217 |
| OTULINL | OTU deubiquitinase with linear linkage specificity like | -0.00613548 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.00612632 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.00609229 |
| COLEC11 | collectin sub-family member 11 | -0.00604701 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.00603068 |
| DKK4 | dickkopf WNT signaling pathway inhibitor 4 | -0.00601567 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | -0.00601097 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00600016 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | -0.00599369 |
| SMS | spermine synthase | -0.00599062 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | -0.00597456 |
| ACE2 | angiotensin I converting enzyme 2 | -0.00597411 |
| PENK | proenkephalin | -0.00596565 |
| ADIRF | adipogenesis regulatory factor | -0.00593563 |
| GUCY2C | guanylate cyclase 2C | -0.00593431 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -0.00589715 |
| NINJ2 | ninjurin 2 | -0.00589503 |
| TMSB15A | thymosin beta 15a | -0.0058714 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00587089 |
| SCG5 | secretogranin V | -0.00584539 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.00584266 |
| CD8A | CD8a molecule | -0.00580839 |
| TKTL1 | transketolase-like 1 | -0.00580373 |
| WDR61 | WD repeat domain 61 | -0.00577957 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.00577335 |
| DPYS | dihydropyrimidinase | -0.00577177 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.00577125 |
| COCH | cochlin | -0.00571342 |
| STC1 | stanniocalcin 1 | -0.00565697 |
| CALB1 | calbindin 1, 28kDa | -0.00564843 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00563284 |
| HMGB2 | high mobility group box 2 | -0.00561996 |
| MRPL48 | mitochondrial ribosomal protein L48 | -0.00561987 |
| RNF167 | ring finger protein 167 | -0.00561329 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | -0.00560615 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.00559982 |
| RNF41 | ring finger protein 41, E3 ubiquitin protein ligase | -0.00559186 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.00558987 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | -0.00558617 |
| ZNF22 | zinc finger protein 22 | -0.00558351 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.00556676 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | -0.00555388 |
| XYLT1 | xylosyltransferase I | -0.00551631 |
| NELL2 | NEL-like 2 (chicken) | -0.00551433 |
| CNR1 | cannabinoid receptor 1 (brain) | -0.00551294 |
| RHOBTB1 | Rho-related BTB domain containing 1 | -0.00549449 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.00549251 |
| AAMDC | adipogenesis associated, Mth938 domain containing | -0.00549057 |
| OLFM1 | olfactomedin 1 | -0.00548411 |
| FADS1 | fatty acid desaturase 1 | -0.0054804 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00547979 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | -0.0054781 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.00547721 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -0.00547653 |
| PTDSS1 | phosphatidylserine synthase 1 | -0.00547555 |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) | -0.00544766 |
| MAOB | monoamine oxidase B | -0.00544283 |
| CD7 | CD7 molecule | -0.00543488 |
| ZFAND1 | zinc finger, AN1-type domain 1 | -0.00543324 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa | -0.00543054 |
| PIPOX | pipecolic acid oxidase | -0.005428 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | -0.0054255 |
| GALC | galactosylceramidase | -0.00540878 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog | -0.0054021 |
| ACVR2A | activin A receptor, type IIA | -0.00540167 |
| CCN3 | cellular communication network factor 3 | -0.00535971 |
| SPATA7 | spermatogenesis associated 7 | -0.00535964 |
| MATN2 | matrilin 2 | -0.00535267 |
| RNASE6 | ribonuclease, RNase A family, k6 | -0.00535201 |
| IFI30 | interferon, gamma-inducible protein 30 | -0.00534481 |
| PHYH | phytanoyl-CoA 2-hydroxylase | -0.00533207 |
| THY1 | Thy-1 cell surface antigen | -0.00528605 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -0.00528159 |
| RTN1 | reticulon 1 | -0.00528025 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00527574 |
| XK | X-linked Kx blood group | -0.00527434 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00527312 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 | -0.00526021 |
| SDCBP | syndecan binding protein (syntenin) | -0.00525715 |
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | -0.00524544 |
| PAH | phenylalanine hydroxylase | -0.00523791 |
| CYBRD1 | cytochrome b reductase 1 | -0.0052366 |
| THBS1 | thrombospondin 1 | -0.00523605 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | -0.00522625 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0052194 |
| ATP11B | ATPase, class VI, type 11B | -0.00521387 |
| CLEC10A | C-type lectin domain family 10, member A | -0.00521125 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.00520978 |
| MME | membrane metallo-endopeptidase | -0.00519475 |
| PDE1A | phosphodiesterase 1A, calmodulin-dependent | -0.00519389 |
| CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant | -0.00517763 |
| TRIM36 | tripartite motif containing 36 | -0.00517496 |
| CYP4A11 | cytochrome P450, family 4, subfamily A, polypeptide 11 | -0.00517092 |
| S100A6 | S100 calcium binding protein A6 | -0.00516673 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | -0.00516511 |
| PNKP | polynucleotide kinase 3'-phosphatase | -0.00516385 |
| SELENBP1 | selenium binding protein 1 | -0.00515636 |
| RNF5 | ring finger protein 5, E3 ubiquitin protein ligase | -0.00515602 |
| C7 | complement component 7 | -0.00515192 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.00515075 |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) | -0.00514326 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | -0.00511729 |
| NTS | neurotensin | -0.00511487 |
| GAP43 | growth associated protein 43 | -0.00511244 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00510277 |
| PAAF1 | proteasomal ATPase-associated factor 1 | -0.00509332 |
| ACP5 | acid phosphatase 5, tartrate resistant | -0.00508891 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -0.00508663 |
| SORD | sorbitol dehydrogenase | -0.00508636 |
| MAL | mal, T-cell differentiation protein | -0.00507566 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.00507066 |
| TPH1 | tryptophan hydroxylase 1 | -0.00504225 |
| CHGB | chromogranin B | -0.00502414 |
| DPP4 | dipeptidyl-peptidase 4 | -0.00502302 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0050177 |
| APEX1 | APEX nuclease (multifunctional DNA repair enzyme) 1 | -0.00501101 |
| KIAA0226L | KIAA0226-like | -0.00499563 |
| WIF1 | WNT inhibitory factor 1 | -0.00498271 |
| EAPP | E2F-associated phosphoprotein | -0.00497903 |
| GLCE | glucuronic acid epimerase | -0.00495878 |
| PAQR3 | progestin and adipoQ receptor family member III | -0.00495555 |
| CASD1 | CAS1 domain containing 1 | -0.00494914 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | -0.00494146 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.00493177 |
| GMPR2 | guanosine monophosphate reductase 2 | -0.00493039 |
| EIF4E | eukaryotic translation initiation factor 4E | -0.00492587 |
| UVRAG | UV radiation resistance associated | -0.00491361 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 | -0.00491116 |
| MBIP | MAP3K12 binding inhibitory protein 1 | -0.00490833 |
| MIA3 | melanoma inhibitory activity family, member 3 | -0.00490728 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | -0.00490581 |
| ACOT9 | acyl-CoA thioesterase 9 | -0.00490423 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 | -0.00489393 |
| PRR16 | proline rich 16 | -0.00488932 |
| SYBU | syntabulin (syntaxin-interacting) | -0.00486796 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 | -0.0048679 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 | -0.00485627 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | -0.00485522 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | -0.00485109 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.00484664 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00483067 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.00482986 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00482758 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.00482204 |
| C3ORF14 | chromosome 3 open reading frame 14 | -0.00481394 |
| CLCA1 | chloride channel accessory 1 | -0.00481247 |
| TMEM14B | transmembrane protein 14B | -0.00481195 |
| TOX3 | TOX high mobility group box family member 3 | -0.00480836 |
| SYT1 | synaptotagmin I | -0.00478973 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | -0.00478338 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | -0.00477578 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | -0.00477519 |
| SELENOW | selenoprotein W | -0.00477302 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | -0.00472785 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | -0.00472491 |
| VPS51 | vacuolar protein sorting 51 homolog (S. cerevisiae) | -0.0047121 |
| DMBT1 | deleted in malignant brain tumors 1 | -0.00471115 |
| GSTT1 | glutathione S-transferase theta 1 | -0.00469611 |
| VDAC3 | voltage-dependent anion channel 3 | -0.00469429 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | -0.00469375 |
| ADK | adenosine kinase | -0.00468574 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | -0.00467465 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.00466823 |
| WASHC4 | WASH complex subunit 4 | -0.0046655 |
| CAVIN3 | caveolae associated protein 3 | -0.00465975 |
| HCK | HCK proto-oncogene, Src family tyrosine kinase | -0.00465599 |
| RPS5 | ribosomal protein S5 | -0.00465177 |
| TSN | translin | -0.00465174 |
| DHCR24 | 24-dehydrocholesterol reductase | -0.00465135 |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 | -0.00464682 |
| PARPBP | PARP1 binding protein | -0.00464336 |
