| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | apolipoprotein B|This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 338) |
| External Link | https://ncbi.nlm.nih.gov/gene/338 |
| Similar Terms | |
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499 genes differentially expressed following the APOB gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| S100A8 | S100 calcium binding protein A8 | 0.0262244 |
| S100A9 | S100 calcium binding protein A9 | 0.0189263 |
| WDR7 | WD repeat domain 7 | 0.0163621 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0157027 |
| FABP7 | fatty acid binding protein 7, brain | 0.0138214 |
| KYNU | kynureninase | 0.0126536 |
| MT1X | metallothionein 1X | 0.0123665 |
| LTF | lactotransferrin | 0.0120814 |
| RRAGA | Ras-related GTP binding A | 0.0116985 |
| S100A12 | S100 calcium binding protein A12 | 0.0111586 |
| MMP7 | matrix metallopeptidase 7 | 0.0109515 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.0109444 |
| LCN2 | lipocalin 2 | 0.0109407 |
| SOX10 | SRY (sex determining region Y)-box 10 | 0.0107458 |
| PITX3 | paired-like homeodomain 3 | 0.01072 |
| SFRP1 | secreted frizzled-related protein 1 | 0.0105255 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0105164 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.0104916 |
| IPO13 | importin 13 | 0.00983209 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00982034 |
| S100A7 | S100 calcium binding protein A7 | 0.00969321 |
| KRT7 | keratin 7, type II | 0.0095898 |
| AK4 | adenylate kinase 4 | 0.00955271 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.00952873 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00946009 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.0092723 |
| BCL2A1 | BCL2-related protein A1 | 0.0090725 |
| KRT15 | keratin 15, type I | 0.00904502 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.00894152 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.00892421 |
| FPR1 | formyl peptide receptor 1 | 0.00889745 |
| GUCY2C | guanylate cyclase 2C | 0.00880247 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00879061 |
| HSPB1 | heat shock 27kDa protein 1 | 0.00868574 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.00860647 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00858846 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 0.00858825 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.0085586 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00854893 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.00852505 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | 0.00852086 |
| METRN | meteorin, glial cell differentiation regulator | 0.00834757 |
| VCAN | versican | 0.00833039 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | 0.00829453 |
| MAL | mal, T-cell differentiation protein | 0.00828944 |
| GPM6B | glycoprotein M6B | 0.00827392 |
| MT1H | metallothionein 1H | 0.00826967 |
| NEBL | nebulette | 0.00824646 |
| PADI2 | peptidyl arginine deiminase, type II | 0.00817149 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00815125 |
| CLDN10 | claudin 10 | 0.00813461 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00813317 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.00805131 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00802113 |
| OPHN1 | oligophrenin 1 | 0.00793564 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.00787712 |
| PLP1 | proteolipid protein 1 | 0.0077622 |
| DCT | dopachrome tautomerase | 0.00774311 |
| CHI3L2 | chitinase 3-like 2 | 0.00773796 |
| TYRP1 | tyrosinase-related protein 1 | 0.0077254 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 0.00764273 |
| PLK1 | polo-like kinase 1 | 0.00761106 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00757353 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 0.00754977 |
| GYPC | glycophorin C (Gerbich blood group) | 0.00745939 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | 0.0074398 |
| MFAP3L | microfibrillar-associated protein 3-like | 0.00739028 |
| AK5 | adenylate kinase 5 | 0.00738408 |
| HBD | hemoglobin, delta | 0.00737111 |
| ALOX5 | arachidonate 5-lipoxygenase | 0.00734589 |
| LINC00623 | long intergenic non-protein coding RNA 623 | 0.00722378 |
| CYBB | cytochrome b-245, beta polypeptide | 0.0072098 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.00711339 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00706202 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.00705942 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.00704877 |
| COPS7A | COP9 signalosome subunit 7A | 0.00704294 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00702742 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0070256 |
| KYAT3 | kynurenine aminotransferase 3 | 0.00700692 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 0.00699431 |
| GLDC | glycine dehydrogenase (decarboxylating) | 0.00698626 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | 0.00693961 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.00693957 |
| MBD2 | methyl-CpG binding domain protein 2 | 0.00686724 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.0068461 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.00683013 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 0.00681052 |
| KRT10 | keratin 10, type I | 0.00674927 |
| NTS | neurotensin | 0.00670552 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | 0.00669184 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | 0.00664624 |
| KLK10 | kallikrein-related peptidase 10 | 0.00662708 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00662471 |
| KRT81 | keratin 81, type II | 0.00661994 |
| EREG | epiregulin | 0.00659479 |
| PLIN3 | perilipin 3 | 0.00657338 |
| RGS17 | regulator of G-protein signaling 17 | 0.00651505 |
| BAX | BCL2-associated X protein | 0.00648935 |
| MDH2 | malate dehydrogenase 2, NAD (mitochondrial) | 0.00643937 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00643527 |
| CSTA | cystatin A (stefin A) | 0.00641988 |
| MT1G | metallothionein 1G | 0.00640803 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00640317 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 0.00640312 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | 0.00640132 |
| C9ORF16 | chromosome 9 open reading frame 16 | 0.00639829 |
| RNF144A | ring finger protein 144A | 0.00633752 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00631365 |
| TRIM29 | tripartite motif containing 29 | 0.00631321 |
| POLE3 | polymerase (DNA directed), epsilon 3, accessory subunit | 0.0063123 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | 0.00630994 |
| TXNL1 | thioredoxin-like 1 | 0.0063064 |
| VSNL1 | visinin-like 1 | 0.0062994 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | 0.00629116 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 0.0062746 |
| MCUB | mitochondrial calcium uniporter dominant negative subunit beta | 0.00627195 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.00627126 |
| IER3IP1 | immediate early response 3 interacting protein 1 | 0.00623665 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 0.00623102 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | 0.00618897 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.00618896 |
| DPYD | dihydropyrimidine dehydrogenase | 0.00612719 |
| VNN2 | vanin 2 | 0.00612718 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.00611214 |
| PNMA8A | PNMA family member 8A | 0.00604481 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | 0.00595124 |
| POPDC3 | popeye domain containing 3 | 0.00594925 |
| TRIM16 | tripartite motif containing 16 | 0.00594191 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00593868 |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) | 0.00593318 |
| HAL | histidine ammonia-lyase | 0.00593171 |
| CDC42SE1 | CDC42 small effector 1 | 0.00592232 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | 0.00589427 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 | 0.00586672 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.00585546 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.00585537 |
| ANXA6 | annexin A6 | 0.00585377 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa | 0.00585016 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.00584475 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.00584448 |
| GAP43 | growth associated protein 43 | 0.00584404 |
| KLK13 | kallikrein-related peptidase 13 | 0.00584129 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.00581186 |
| EAF2 | ELL associated factor 2 | 0.00580893 |
| ZNF264 | zinc finger protein 264 | 0.00580374 |
| ZNF226 | zinc finger protein 226 | 0.0057882 |
| ZNF274 | zinc finger protein 274 | 0.00577739 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | 0.00574754 |
| FHIT | fragile histidine triad | 0.00572587 |
| CDC20 | cell division cycle 20 | 0.00571867 |
| CTBS | chitobiase, di-N-acetyl- | 0.00571679 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.00571469 |
| SCEL | sciellin | 0.00570587 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.00567934 |
| GFAP | glial fibrillary acidic protein | 0.0056776 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | 0.00566349 |
| TSPO | translocator protein (18kDa) | 0.00564148 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00564146 |
| SELL | selectin L | 0.00563876 |
| CD38 | CD38 molecule | 0.00561537 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.0056064 |
| HOPX | HOP homeobox | 0.00559269 |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 | 0.00558858 |
| PRKCA | protein kinase C, alpha | 0.00557492 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.00556873 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.005559 |
| DOK5 | docking protein 5 | 0.0055553 |
| TMEM45A | transmembrane protein 45A | 0.00555285 |
| CCDC81 | coiled-coil domain containing 81 | 0.0055359 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.00552986 |
| PF4 | platelet factor 4 | 0.005527 |
| MNDA | myeloid cell nuclear differentiation antigen | 0.00551818 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.00549844 |
| RGS4 | regulator of G-protein signaling 4 | 0.00549204 |
| PRKCQ | protein kinase C, theta | 0.0054916 |
| RGS10 | regulator of G-protein signaling 10 | 0.00548962 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.00548752 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.00548644 |
| CTSS | cathepsin S | 0.00546451 |
| RELN | reelin | 0.00546424 |
| MT1F | metallothionein 1F | 0.00546073 |
| COMT | catechol-O-methyltransferase | 0.00544448 |
| LY86 | lymphocyte antigen 86 | 0.00543924 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | 0.00543119 |
| TXNIP | thioredoxin interacting protein | 0.00541049 |
| KLK8 | kallikrein-related peptidase 8 | 0.00539633 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | 0.00539369 |
| CRABP1 | cellular retinoic acid binding protein 1 | 0.00538878 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 | 0.00538224 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | 0.00537775 |
| AHSP | alpha hemoglobin stabilizing protein | 0.00536274 |
| TMED3 | transmembrane emp24 protein transport domain containing 3 | 0.00536131 |
| RANBP6 | RAN binding protein 6 | 0.00535218 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.00534904 |
| MT3 | metallothionein 3 | 0.00534418 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.00534276 |
| SRPRB | signal recognition particle receptor, B subunit | 0.00534226 |
| CORO1A | coronin, actin binding protein, 1A | 0.00530436 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.00529005 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.00528821 |
| PROM1 | prominin 1 | 0.00527493 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.00525743 |
| NRCAM | neuronal cell adhesion molecule | 0.00523746 |
| QRSL1 | glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 | 0.00523234 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | 0.0052305 |
| EIF3I | eukaryotic translation initiation factor 3, subunit I | 0.00522331 |
| DPH5 | diphthamide biosynthesis 5 | 0.00521375 |
| ARRB2 | arrestin, beta 2 | 0.00520335 |
| C1RL | complement component 1, r subcomponent-like | 0.00518712 |
| GAS1 | growth arrest-specific 1 | 0.00517807 |
| KRT1 | keratin 1, type II | 0.00517795 |
| TLR5 | toll-like receptor 5 | 0.00517692 |
| KLK7 | kallikrein-related peptidase 7 | 0.00516743 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.0051608 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | 0.00515796 |
| ADD3 | adducin 3 (gamma) | 0.00515129 |
| NDUFA3 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa | 0.00514496 |
| NDRG2 | NDRG family member 2 | 0.00513759 |
| PRKD1 | protein kinase D1 | 0.00512719 |
| SLC25A11 | solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 | 0.00510929 |
| MT2A | metallothionein 2A | 0.00510872 |
| ZNF91 | zinc finger protein 91 | 0.00510069 |
| SHCBP1 | SHC SH2-domain binding protein 1 | 0.00509166 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.00508965 |
| MPO | myeloperoxidase | 0.0050825 |
| F12 | coagulation factor XII (Hageman factor) | 0.00506047 |
| HHLA3 | HERV-H LTR-associating 3 | 0.00505866 |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A | 0.00505435 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.00505175 |
| LILRA2 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 | 0.0050408 |
| PLPBP | pyridoxal phosphate binding protein | 0.00503711 |
| TMEM160 | transmembrane protein 160 | 0.0050325 |
| RPP40 | ribonuclease P/MRP 40kDa subunit | 0.00502885 |
| CHPT1 | choline phosphotransferase 1 | 0.00502356 |
| PYGB | phosphorylase, glycogen; brain | 0.00502056 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | 0.00500203 |
| ICAM2 | intercellular adhesion molecule 2 | 0.00497832 |
| MZB1 | marginal zone B and B1 cell-specific protein | 0.00497421 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00497404 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00496489 |
| SV2A | synaptic vesicle glycoprotein 2A | 0.00496408 |
| ACO1 | aconitase 1, soluble | 0.00496379 |
| DHCR24 | 24-dehydrocholesterol reductase | 0.00496123 |
| HPF1 | histone PARylation factor 1 | 0.0049595 |
| PSMB6 | proteasome (prosome, macropain) subunit, beta type, 6 | 0.00495902 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | 0.00495865 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.00495414 |
| STC1 | stanniocalcin 1 | 0.00494662 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 | 0.00494402 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IFI27 | interferon, alpha-inducible protein 27 | -0.0216441 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.0208069 |
| TCTA | T-cell leukemia translocation altered | -0.0142445 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.0135388 |
| GNAS | GNAS complex locus | -0.012498 |
| BST2 | bone marrow stromal cell antigen 2 | -0.0124814 |
| HSPB8 | heat shock 22kDa protein 8 | -0.0124657 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0123616 |
| ADIRF | adipogenesis regulatory factor | -0.012348 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.0118663 |
| RGS5 | regulator of G-protein signaling 5 | -0.0116661 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.0107372 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -0.0105904 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.0105455 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0105351 |
| KRT18 | keratin 18, type I | -0.0104659 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0103684 |
| MFAP4 | microfibrillar-associated protein 4 | -0.0101099 |
| IFI44L | interferon-induced protein 44-like | -0.00969453 |
| MECOM | MDS1 and EVI1 complex locus | -0.00936318 |
| POSTN | periostin, osteoblast specific factor | -0.00935006 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00931725 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.00922395 |
| MIR22HG | MIR22 host gene | -0.00910383 |
| MX1 | MX dynamin-like GTPase 1 | -0.00895604 |
| GPC3 | glypican 3 | -0.00893253 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00892537 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00882426 |
| CA2 | carbonic anhydrase II | -0.00871072 |
| PALLD | palladin, cytoskeletal associated protein | -0.00871044 |
| MFAP2 | microfibrillar-associated protein 2 | -0.00870945 |
| CLEC3B | C-type lectin domain family 3, member B | -0.00856205 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00841058 |
| ATF3 | activating transcription factor 3 | -0.00840651 |
| RNPS1 | RNA binding protein S1, serine-rich domain | -0.00839477 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | -0.00837928 |
| SOX11 | SRY (sex determining region Y)-box 11 | -0.0083628 |
| BRD4 | bromodomain containing 4 | -0.00836279 |
| LIMA1 | LIM domain and actin binding 1 | -0.008342 |
| SH3BP4 | SH3-domain binding protein 4 | -0.00829943 |
| AGR2 | anterior gradient 2 | -0.00823274 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00817764 |
| TSPAN8 | tetraspanin 8 | -0.0081637 |
| COL3A1 | collagen, type III, alpha 1 | -0.00798865 |
| G0S2 | G0/G1 switch 2 | -0.00798409 |
| PDGFC | platelet derived growth factor C | -0.00797432 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00797355 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.00797258 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00789013 |
| RCAN2 | regulator of calcineurin 2 | -0.00782755 |
| EZR | ezrin | -0.00781723 |
| LPAR1 | lysophosphatidic acid receptor 1 | -0.00774435 |
| ANXA3 | annexin A3 | -0.00773438 |
| CCND1 | cyclin D1 | -0.00765622 |
| PER3 | period circadian clock 3 | -0.00753151 |
| S100A10 | S100 calcium binding protein A10 | -0.00751271 |
| FBLN1 | fibulin 1 | -0.00748449 |
| JMJD1C | jumonji domain containing 1C | -0.00747103 |
| EFNB2 | ephrin-B2 | -0.00745288 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.00744766 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.00742998 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00741185 |
| SEPTIN10 | septin 10 | -0.0074112 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.00740185 |
| NDNF | neuron-derived neurotrophic factor | -0.00738231 |
| SPAG9 | sperm associated antigen 9 | -0.00736816 |
| EGFL6 | EGF-like-domain, multiple 6 | -0.00734549 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00734338 |
| PRDX2 | peroxiredoxin 2 | -0.00731325 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | -0.00731223 |
| PCDH17 | protocadherin 17 | -0.00729908 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.0072898 |
| VWF | von Willebrand factor | -0.00726905 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.00725828 |
| COL1A1 | collagen, type I, alpha 1 | -0.00723051 |
| CPE | carboxypeptidase E | -0.00720421 |
| LUM | lumican | -0.00716969 |
| AMOTL2 | angiomotin like 2 | -0.00713165 |
| CAVIN3 | caveolae associated protein 3 | -0.00711334 |
| GSN | gelsolin | -0.00711227 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00710285 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -0.00703141 |
| CLIC5 | chloride intracellular channel 5 | -0.00700776 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00697279 |
| BMP2 | bone morphogenetic protein 2 | -0.00697045 |
| TSPAN13 | tetraspanin 13 | -0.00696577 |
| FRZB | frizzled-related protein | -0.00693809 |
| PLA1A | phospholipase A1 member A | -0.00689441 |
| ELN | elastin | -0.00689435 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.00683735 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | -0.00683039 |
| FN1 | fibronectin 1 | -0.00681742 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.00680891 |
| LOXL1 | lysyl oxidase-like 1 | -0.00678545 |
| NEMP1 | nuclear envelope integral membrane protein 1 | -0.00676711 |
| DPT | dermatopontin | -0.00676189 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 | -0.00674537 |
| TBX3 | T-box 3 | -0.00673424 |
| GOLM1 | golgi membrane protein 1 | -0.00673208 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.00672312 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.00671162 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00665181 |
| ITGA6 | integrin, alpha 6 | -0.00665065 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.00662645 |
| DAAM2 | dishevelled associated activator of morphogenesis 2 | -0.00662192 |
| TNS1 | tensin 1 | -0.00661757 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.00661382 |
| MGLL | monoglyceride lipase | -0.00659789 |
| ARG2 | arginase 2 | -0.00657151 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00657097 |
| AKAP17A | A kinase (PRKA) anchor protein 17A | -0.00656958 |
| CBX1 | chromobox homolog 1 | -0.00656759 |
| ASPN | asporin | -0.00648247 |
| BMP4 | bone morphogenetic protein 4 | -0.00646678 |
| MSX1 | msh homeobox 1 | -0.0064319 |
| DACH1 | dachshund family transcription factor 1 | -0.00642965 |
| PNN | pinin, desmosome associated protein | -0.0064293 |
| RUFY3 | RUN and FYVE domain containing 3 | -0.006428 |
| RGCC | regulator of cell cycle | -0.00642747 |
| SMAD7 | SMAD family member 7 | -0.00641661 |
| NEFH | neurofilament, heavy polypeptide | -0.00641403 |
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | -0.00639336 |
| ZG16 | zymogen granule protein 16 | -0.00638792 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 | -0.0063532 |
| ARHGAP44 | Rho GTPase activating protein 44 | -0.00634923 |
| PLXNA2 | plexin A2 | -0.00634326 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0063384 |
| TMEM131 | transmembrane protein 131 | -0.00633711 |
| KIAA0232 | KIAA0232 | -0.00633267 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.00631688 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.00627081 |
| DUSP5 | dual specificity phosphatase 5 | -0.00625436 |
| STX3 | syntaxin 3 | -0.00622441 |
| MMP1 | matrix metallopeptidase 1 | -0.00622317 |
| EDNRA | endothelin receptor type A | -0.0062167 |
| PRKCZ | protein kinase C, zeta | -0.00621395 |
| COL16A1 | collagen, type XVI, alpha 1 | -0.00620474 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00619131 |
| KHNYN | KH and NYN domain containing | -0.00617617 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) | -0.00617476 |
| FMOD | fibromodulin | -0.00616 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | -0.00610469 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | -0.00610099 |
| TCF4 | transcription factor 4 | -0.00605975 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.00605317 |
| ACKR3 | atypical chemokine receptor 3 | -0.00604773 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00604116 |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | -0.00601361 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.00600837 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00600441 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.00597862 |
| MAP7 | microtubule-associated protein 7 | -0.00597004 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00594429 |
| RUBCN | rubicon autophagy regulator | -0.00593872 |
| WLS | wntless Wnt ligand secretion mediator | -0.00590063 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00588024 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | -0.00586722 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0058629 |
| PKP2 | plakophilin 2 | -0.00584112 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.00582566 |
| RBM5 | RNA binding motif protein 5 | -0.00579287 |
| HIC2 | hypermethylated in cancer 2 | -0.00573871 |
| CA4 | carbonic anhydrase IV | -0.00572757 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0057265 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.00572115 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | -0.0057118 |
| GOLIM4 | golgi integral membrane protein 4 | -0.00569796 |
| TJP2 | tight junction protein 2 | -0.00569649 |
| SDCBP | syndecan binding protein (syntenin) | -0.00569617 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0056908 |
| TOX3 | TOX high mobility group box family member 3 | -0.00568572 |
| MEP1A | meprin A, alpha (PABA peptide hydrolase) | -0.00568527 |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | -0.00568199 |
| CARD10 | caspase recruitment domain family, member 10 | -0.00567518 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | -0.00566974 |
| ADRA2A | adrenoceptor alpha 2A | -0.00566693 |
| JUND | jun D proto-oncogene | -0.00566093 |
| PHKA2 | phosphorylase kinase, alpha 2 (liver) | -0.00566074 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | -0.0056553 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | -0.00564766 |
| L1CAM | L1 cell adhesion molecule | -0.00563209 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | -0.00562758 |
| COMP | cartilage oligomeric matrix protein | -0.00561968 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00561644 |
| STK10 | serine/threonine kinase 10 | -0.00561314 |
| CES1 | carboxylesterase 1 | -0.00561127 |
| STK26 | serine/threonine protein kinase 26 | -0.00558032 |
| DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A | -0.00556982 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.00555144 |
| FILIP1L | filamin A interacting protein 1-like | -0.00554532 |
| FZD5 | frizzled class receptor 5 | -0.00553085 |
| ODC1 | ornithine decarboxylase 1 | -0.00553044 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -0.0055269 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.00552002 |
| SPEN | spen family transcriptional repressor | -0.0055131 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.00551122 |
| BTG3 | BTG family, member 3 | -0.00550177 |
| CCN2 | cellular communication network factor 2 | -0.00549334 |
| SOWAHC | sosondowah ankyrin repeat domain family member C | -0.00548682 |
| SFN | stratifin | -0.00545874 |
| SI | sucrase-isomaltase (alpha-glucosidase) | -0.00545765 |
| PJA1 | praja ring finger 1, E3 ubiquitin protein ligase | -0.00544032 |
| RETREG2 | reticulophagy regulator family member 2 | -0.00543961 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.00543263 |
| PLXND1 | plexin D1 | -0.00542361 |
| CAPG | capping protein (actin filament), gelsolin-like | -0.00540678 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | -0.00540593 |
| IGF1R | insulin-like growth factor 1 receptor | -0.00540271 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.00538693 |
| GPX3 | glutathione peroxidase 3 | -0.00538337 |
| ACOT7 | acyl-CoA thioesterase 7 | -0.00537637 |
| DNMBP | dynamin binding protein | -0.00536847 |
| KLF4 | Kruppel-like factor 4 (gut) | -0.00536328 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | -0.00535922 |
| SERTAD2 | SERTA domain containing 2 | -0.00535713 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 | -0.00535576 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | -0.00535423 |
| C1QA | complement component 1, q subcomponent, A chain | -0.0053433 |
| ACE2 | angiotensin I converting enzyme 2 | -0.00532846 |
| NNT | nicotinamide nucleotide transhydrogenase | -0.00532271 |
| RET | ret proto-oncogene | -0.0053227 |
| IRF9 | interferon regulatory factor 9 | -0.00531826 |
| LRRC15 | leucine rich repeat containing 15 | -0.00527671 |
| ARAP3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 | -0.00527623 |
| UBE3B | ubiquitin protein ligase E3B | -0.00527254 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.00526854 |
| HOXC10 | homeobox C10 | -0.00524076 |
| TMSB15A | thymosin beta 15a | -0.00523294 |
| PILRB | paired immunoglobin-like type 2 receptor beta | -0.00522055 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | -0.00521919 |
| LAMA2 | laminin, alpha 2 | -0.00520803 |
| SCARB2 | scavenger receptor class B, member 2 | -0.00520762 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.00520597 |
| GAB2 | GRB2-associated binding protein 2 | -0.00520548 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0052052 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | -0.00519928 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 | -0.00519419 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | -0.00518911 |
| GUCA2A | guanylate cyclase activator 2A (guanylin) | -0.00518597 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.00518106 |
| PTN | pleiotrophin | -0.00517713 |
| DOK4 | docking protein 4 | -0.00516719 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | -0.00516111 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | -0.00515876 |
| RUNX3 | runt-related transcription factor 3 | -0.00515846 |
| ZBED5 | zinc finger, BED-type containing 5 | -0.00514232 |
| CDA | cytidine deaminase | -0.00513849 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 | -0.00513251 |
| TPD52 | tumor protein D52 | -0.00513188 |
