| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | apolipoprotein E|The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014] (NCBI Entrez Gene Database, 348) |
| External Link | https://ncbi.nlm.nih.gov/gene/348 |
| Similar Terms | |
| Downloads & Tools |
497 genes differentially expressed following the APOE gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CLU | clusterin | 0.0105152 |
| OLFM1 | olfactomedin 1 | 0.00967747 |
| NPTX2 | neuronal pentraxin II | 0.00847858 |
| HBB | hemoglobin, beta | 0.0070622 |
| SYNM | synemin, intermediate filament protein | 0.00697097 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.0069444 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.00679678 |
| TUBB2B | tubulin, beta 2B class IIb | 0.00672295 |
| DAXX | death-domain associated protein | 0.00655401 |
| SPC25 | SPC25, NDC80 kinetochore complex component | 0.00652825 |
| RPA3 | replication protein A3, 14kDa | 0.00651423 |
| KIF5C | kinesin family member 5C | 0.00646975 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.00635753 |
| CHN1 | chimerin 1 | 0.00634453 |
| ACKR3 | atypical chemokine receptor 3 | 0.00633529 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | 0.006292 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.00621691 |
| TMEM14A | transmembrane protein 14A | 0.00617291 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00616321 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.00615591 |
| L1CAM | L1 cell adhesion molecule | 0.00613396 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.00606491 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | 0.00603987 |
| NELL2 | NEL-like 2 (chicken) | 0.0059824 |
| PLP1 | proteolipid protein 1 | 0.00594202 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.00592097 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00583639 |
| SELE | selectin E | 0.00582784 |
| NEFH | neurofilament, heavy polypeptide | 0.00580919 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | 0.00580745 |
| CADM1 | cell adhesion molecule 1 | 0.00578716 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | 0.00575573 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00572561 |
| GPM6B | glycoprotein M6B | 0.00570297 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | 0.00568567 |
| RELN | reelin | 0.00553172 |
| SYBU | syntabulin (syntaxin-interacting) | 0.00551711 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00549907 |
| AGTR1 | angiotensin II receptor, type 1 | 0.00546646 |
| EPAS1 | endothelial PAS domain protein 1 | 0.00546318 |
| PIR | pirin (iron-binding nuclear protein) | 0.00544444 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00543591 |
| TMSB15A | thymosin beta 15a | 0.00536402 |
| FOLR1 | folate receptor 1 (adult) | 0.00536243 |
| FABP7 | fatty acid binding protein 7, brain | 0.00535024 |
| HOXB7 | homeobox B7 | 0.00530335 |
| MAL | mal, T-cell differentiation protein | 0.00528003 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.00525731 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.00522718 |
| PER3 | period circadian clock 3 | 0.00520594 |
| LPAR6 | lysophosphatidic acid receptor 6 | 0.0051778 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | 0.00516887 |
| GRB7 | growth factor receptor-bound protein 7 | 0.0051612 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.00513517 |
| SHCBP1 | SHC SH2-domain binding protein 1 | 0.00511049 |
| S100B | S100 calcium binding protein B | 0.00510486 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00507607 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00507142 |
| PTN | pleiotrophin | 0.00506664 |
| DHCR24 | 24-dehydrocholesterol reductase | 0.00504094 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00501595 |
| ACP3 | acid phosphatase 3 | 0.00500651 |
| PLK1 | polo-like kinase 1 | 0.00500117 |
| DMAC2L | distal membrane arm assembly component 2 like | 0.00497519 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00496015 |
| MAGEA3 | melanoma antigen family A3 | 0.00493691 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00487863 |
| AK4 | adenylate kinase 4 | 0.00487268 |
| GAP43 | growth associated protein 43 | 0.00487112 |
| NRN1 | neuritin 1 | 0.00481639 |
| SOX10 | SRY (sex determining region Y)-box 10 | 0.00481011 |
| PTGES | prostaglandin E synthase | 0.00477967 |
| FOXF1 | forkhead box F1 | 0.00477647 |
| CFH | complement factor H | 0.00473469 |
| KRT13 | keratin 13, type I | 0.00472564 |
| NTS | neurotensin | 0.00471141 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | 0.00470994 |
| CCNF | cyclin F | 0.0046994 |
| PRDX4 | peroxiredoxin 4 | 0.00469662 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.00468917 |
| CFD | complement factor D (adipsin) | 0.00468715 |
| KIF20A | kinesin family member 20A | 0.00467728 |
| GSTT1 | glutathione S-transferase theta 1 | 0.00465518 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.00462997 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.0046242 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | 0.00462233 |
| AMPH | amphiphysin | 0.00461391 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00455145 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.0045463 |
| FRZB | frizzled-related protein | 0.00453085 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00448812 |
| MXI1 | MAX interactor 1, dimerization protein | 0.00447431 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00446792 |
| DMD | dystrophin | 0.00446098 |
| CHEK1 | checkpoint kinase 1 | 0.00443127 |
| NLGN4X | neuroligin 4, X-linked | 0.00442827 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.0044022 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | 0.00439979 |
| CDCA4 | cell division cycle associated 4 | 0.00439821 |
| CFI | complement factor I | 0.00438913 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00436494 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.00436397 |
| CCNA2 | cyclin A2 | 0.00434217 |
| PCNA | proliferating cell nuclear antigen | 0.00431532 |
| NMU | neuromedin U | 0.00429774 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.00428605 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 0.00427697 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | 0.00427441 |
| ORC1 | origin recognition complex, subunit 1 | 0.00426978 |
| GIMAP4 | GTPase, IMAP family member 4 | 0.00426325 |
| MRPS18B | mitochondrial ribosomal protein S18B | 0.00426122 |
| POGLUT2 | protein O-glucosyltransferase 2 | 0.00422416 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) | 0.00421225 |
| ACTB | actin, beta | 0.00420695 |
| DENND1A | DENN/MADD domain containing 1A | 0.00419361 |
| TMEM45A | transmembrane protein 45A | 0.00416028 |
| TRIM9 | tripartite motif containing 9 | 0.00415767 |
| WFDC1 | WAP four-disulfide core domain 1 | 0.00411719 |
| SLC17A6 | solute carrier family 17 (vesicular glutamate transporter), member 6 | 0.0041159 |
| GPR65 | G protein-coupled receptor 65 | 0.00411186 |
| C3ORF14 | chromosome 3 open reading frame 14 | 0.00409298 |
| MCAM | melanoma cell adhesion molecule | 0.00406689 |
| COX15 | cytochrome c oxidase assembly homolog 15 (yeast) | 0.00403044 |
| AGA | aspartylglucosaminidase | 0.00402922 |
| DCHS1 | dachsous cadherin-related 1 | 0.00402238 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 0.00400832 |
| PRR15L | proline rich 15-like | 0.0039987 |
| DES | desmin | 0.00399605 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0039917 |
| B3GNT1 | 0.00398972 | |
| NHLH2 | nescient helix loop helix 2 | 0.00398922 |
| CETN2 | centrin, EF-hand protein, 2 | 0.00398854 |
| CCNE2 | cyclin E2 | 0.00398809 |
| KLHL7 | kelch-like family member 7 | 0.00398176 |
| NOVA1 | neuro-oncological ventral antigen 1 | 0.00397459 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 0.00397424 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.00397144 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | 0.00397111 |
| PFDN4 | prefoldin subunit 4 | 0.00396988 |
| GPM6A | glycoprotein M6A | 0.00396473 |
| FZD5 | frizzled class receptor 5 | 0.00395113 |
| DUOX2 | dual oxidase 2 | 0.00394407 |
| NKX3-1 | NK3 homeobox 1 | 0.00394253 |
| FBXO5 | F-box protein 5 | 0.00394189 |
| SELENBP1 | selenium binding protein 1 | 0.00394134 |
| STATH | statherin | 0.00393912 |
| FBXO11 | F-box protein 11 | 0.00393839 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00392444 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.00392408 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.0039131 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.00390243 |
| DCTN4 | dynactin 4 (p62) | 0.00389364 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.00388015 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.00385476 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 0.00384304 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | 0.00384182 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | 0.00383763 |
| FERMT2 | fermitin family member 2 | 0.00383674 |
| HOXB6 | homeobox B6 | 0.00381762 |
| CCL8 | chemokine (C-C motif) ligand 8 | 0.00381391 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | 0.00379843 |
| ANXA10 | annexin A10 | 0.00379477 |
| PNMA1 | paraneoplastic Ma antigen 1 | 0.00379055 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.00377525 |
| FCGBP | Fc fragment of IgG binding protein | 0.00376415 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 | 0.00376107 |
| RCAN1 | regulator of calcineurin 1 | 0.00376107 |
| PRKX | protein kinase, X-linked | 0.00375959 |
| SDC2 | syndecan 2 | 0.00375345 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.00374307 |
| EXO1 | exonuclease 1 | 0.00374125 |
| KIF18A | kinesin family member 18A | 0.0037335 |
| GIMAP6 | GTPase, IMAP family member 6 | 0.00373216 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.00373164 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 | 0.00373032 |
| NGRN | neugrin, neurite outgrowth associated | 0.00372263 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.00371968 |
| HAT1 | histone acetyltransferase 1 | 0.00371552 |
| ZNF395 | zinc finger protein 395 | 0.00370171 |
| ALPL | alkaline phosphatase, liver/bone/kidney | 0.00369914 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.00368355 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 | 0.0036827 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00368136 |
| HMGN3 | high mobility group nucleosomal binding domain 3 | 0.00367536 |
| RHOA | ras homolog family member A | 0.00367507 |
| SAP30 | Sin3A-associated protein, 30kDa | 0.00366904 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | 0.00366648 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | 0.00366561 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.00366434 |
| PDGFC | platelet derived growth factor C | 0.003664 |
| DHTKD1 | dehydrogenase E1 and transketolase domain containing 1 | 0.00365999 |
| ACE2 | angiotensin I converting enzyme 2 | 0.00365969 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.0036568 |
| CDC42EP4 | CDC42 effector protein (Rho GTPase binding) 4 | 0.0036565 |
| PTH2R | parathyroid hormone 2 receptor | 0.00364846 |
| EGR2 | early growth response 2 | 0.00363885 |
| ARG2 | arginase 2 | 0.00363841 |
| MAPK13 | mitogen-activated protein kinase 13 | 0.00363572 |
| NANOG | Nanog homeobox | 0.0036302 |
| NSG1 | neuron specific gene family member 1 | 0.00362187 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.00360226 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.00358131 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | 0.00357595 |
| NIBAN1 | niban apoptosis regulator 1 | 0.00357049 |
| ASS1 | argininosuccinate synthase 1 | 0.00355787 |
| STOM | stomatin | 0.00355118 |
| PIP | prolactin-induced protein | 0.00354291 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | 0.00354171 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | 0.003523 |
| UBE2J1 | ubiquitin-conjugating enzyme E2, J1 | 0.00350584 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | 0.00350424 |
| MAOB | monoamine oxidase B | 0.0034961 |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | 0.00349479 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 0.00349093 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00348456 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00348236 |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.00348198 |
| CNR1 | cannabinoid receptor 1 (brain) | 0.00347083 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 0.00346702 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 0.00346108 |
| NAP1L2 | nucleosome assembly protein 1-like 2 | 0.00346014 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 | 0.00345266 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00344926 |
| PQBP1 | polyglutamine binding protein 1 | 0.0034388 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.00343684 |
| SCARA3 | scavenger receptor class A, member 3 | 0.00343578 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.00342019 |
| ENO1 | enolase 1, (alpha) | 0.00341483 |
| KYNU | kynureninase | 0.00341479 |
| CDCA3 | cell division cycle associated 3 | 0.00341419 |
| ZNF217 | zinc finger protein 217 | 0.00340278 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | 0.00339737 |
| RNASEH2A | ribonuclease H2, subunit A | 0.00338516 |
| PBK | PDZ binding kinase | 0.00338501 |
| C7 | complement component 7 | 0.00338005 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00337866 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00337833 |
| GAS2 | growth arrest-specific 2 | 0.00337665 |
| SRSF6 | serine/arginine-rich splicing factor 6 | 0.00337277 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 | 0.00336917 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | 0.00336708 |
| CHRM3 | cholinergic receptor, muscarinic 3 | 0.00335781 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00335647 |
| KAZN | kazrin, periplakin interacting protein | 0.00335286 |
| RAB20 | RAB20, member RAS oncogene family | 0.00334713 |
| ZNF267 | zinc finger protein 267 | 0.00334613 |
| COPS7A | COP9 signalosome subunit 7A | 0.00334577 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.00334469 |
| SKA1 | spindle and kinetochore associated complex subunit 1 | 0.00334293 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.010906 |
| INHBA | inhibin, beta A | -0.00984918 |
| S100A8 | S100 calcium binding protein A8 | -0.00852404 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00845147 |
| XIC | X chromosome inactivation center | -0.00818021 |
| POSTN | periostin, osteoblast specific factor | -0.00792925 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.007826 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | -0.00774681 |
| LCN2 | lipocalin 2 | -0.0073811 |
| CD9 | CD9 molecule | -0.00731159 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0072552 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00715399 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00703872 |
| AEBP1 | AE binding protein 1 | -0.00688524 |
| MMP1 | matrix metallopeptidase 1 | -0.00688522 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.00687256 |
| G0S2 | G0/G1 switch 2 | -0.00687203 |
| RGS2 | regulator of G-protein signaling 2 | -0.0068045 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.00649409 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.00642655 |
| LXN | latexin | -0.00638557 |
| CEL | carboxyl ester lipase | -0.00635487 |
| RGS4 | regulator of G-protein signaling 4 | -0.00631455 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | -0.00628274 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00610104 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00609328 |
| MAP7 | microtubule-associated protein 7 | -0.00607939 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.00605619 |
| NOTCH1 | notch 1 | -0.00596897 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.00592929 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.00591967 |
| RNH1 | ribonuclease/angiogenin inhibitor 1 | -0.0059172 |
| SFTPB | surfactant protein B | -0.00586991 |
| TCF4 | transcription factor 4 | -0.00579905 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00576435 |
| THBS2 | thrombospondin 2 | -0.00573978 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | -0.00571452 |
| NOTCH2NL | notch 2 N-terminal like | -0.00570369 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00568679 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.00557369 |
| CLEC11A | C-type lectin domain family 11, member A | -0.00557134 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.00552597 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | -0.00552382 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00545688 |
| IPO13 | importin 13 | -0.00543383 |
| GPX7 | glutathione peroxidase 7 | -0.00541872 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0053471 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00532462 |
| ASPN | asporin | -0.00531329 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00525942 |
| COMP | cartilage oligomeric matrix protein | -0.0052147 |
| MAGED1 | melanoma antigen family D1 | -0.00520265 |
| SULF1 | sulfatase 1 | -0.00518297 |
| TSPYL5 | TSPY-like 5 | -0.00516565 |
| KRT18 | keratin 18, type I | -0.00513635 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | -0.0050973 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00507415 |
| PXDN | peroxidasin | -0.00506945 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0050589 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -0.00503532 |
| PTK2B | protein tyrosine kinase 2 beta | -0.0050226 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.00501497 |
| ATP10D | ATPase, class V, type 10D | -0.00497266 |
| MT1E | metallothionein 1E | -0.0049609 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -0.00495044 |
| BAX | BCL2-associated X protein | -0.00494849 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | -0.00493434 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.00487164 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | -0.00486359 |
| FN1 | fibronectin 1 | -0.00486315 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | -0.00482074 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | -0.00481537 |
| H2AX | H2A.X variant histone | -0.00476792 |
| COL16A1 | collagen, type XVI, alpha 1 | -0.00474507 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00474176 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.00472346 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.00470797 |
| GAS6 | growth arrest-specific 6 | -0.00469051 |
| AZU1 | azurocidin 1 | -0.00467254 |
| PLS3 | plastin 3 | -0.00465739 |
| EXT1 | exostosin glycosyltransferase 1 | -0.00463128 |
| FNDC3B | fibronectin type III domain containing 3B | -0.00460531 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -0.00460156 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00456131 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.00453191 |
| JUNB | jun B proto-oncogene | -0.0045298 |
| MCM2 | minichromosome maintenance complex component 2 | -0.00450746 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00448429 |
| TM7SF2 | transmembrane 7 superfamily member 2 | -0.00446999 |
| CD44 | CD44 molecule (Indian blood group) | -0.004462 |
| KIAA0355 | KIAA0355 | -0.00442235 |
| APOC1 | apolipoprotein C-I | -0.00440443 |
| MED13 | mediator complex subunit 13 | -0.00439874 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.00436921 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.00435353 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 | -0.00434517 |
| MMP9 | matrix metallopeptidase 9 | -0.00432787 |
| HIRA | histone cell cycle regulator | -0.00430556 |
| KLF2 | Kruppel-like factor 2 | -0.00430275 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | -0.00428567 |
| REXO2 | RNA exonuclease 2 | -0.00427152 |
| AAMDC | adipogenesis associated, Mth938 domain containing | -0.00425649 |
| NPY | neuropeptide Y | -0.00424378 |
| MYH10 | myosin, heavy chain 10, non-muscle | -0.004243 |
| DNM1L | dynamin 1-like | -0.00423986 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | -0.00423248 |
| SQOR | sulfide quinone oxidoreductase | -0.00422028 |
| SFTPA2 | surfactant protein A2 | -0.00421898 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | -0.00421258 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit | -0.00419917 |
| LIPG | lipase, endothelial | -0.00419338 |
| CST6 | cystatin E/M | -0.00418834 |
| PKD1P1 | polycystic kidney disease 1 (autosomal dominant) pseudogene 1 | -0.00418628 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00417886 |
| EXPH5 | exophilin 5 | -0.00417731 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.00416431 |
| MBTPS1 | membrane-bound transcription factor peptidase, site 1 | -0.00414552 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.00413607 |
| CLTB | clathrin, light chain B | -0.00413384 |
| PDE4DIP | phosphodiesterase 4D interacting protein | -0.00412133 |
| EFNB2 | ephrin-B2 | -0.00412071 |
| ZNF544 | zinc finger protein 544 | -0.00408979 |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) | -0.00406978 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00406877 |
| SIX1 | SIX homeobox 1 | -0.00405889 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.00405875 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | -0.00402129 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | -0.00402016 |
| ELANE | elastase, neutrophil expressed | -0.00401793 |
| USP47 | ubiquitin specific peptidase 47 | -0.0040104 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.00400956 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.00400891 |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa | -0.00400532 |
| ABHD17A | abhydrolase domain containing 17A | -0.00399306 |
| PRSS3 | protease, serine, 3 | -0.00398835 |
| ABHD2 | abhydrolase domain containing 2 | -0.00398395 |
| KLHL24 | kelch-like family member 24 | -0.00397384 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.00397322 |
| TSPAN13 | tetraspanin 13 | -0.00395818 |
| MMP11 | matrix metallopeptidase 11 | -0.00395496 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.00395457 |
| EMILIN1 | elastin microfibril interfacer 1 | -0.00393816 |
| ADAM8 | ADAM metallopeptidase domain 8 | -0.0039372 |
| ACTN1 | actinin, alpha 1 | -0.00393526 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.00393375 |
| TMEM41B | transmembrane protein 41B | -0.0039142 |
| IPO7 | importin 7 | -0.00391115 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | -0.00391034 |
| AMPD3 | adenosine monophosphate deaminase 3 | -0.00391012 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00390381 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | -0.00389775 |
| NPEPL1 | aminopeptidase-like 1 | -0.00388967 |
| CAPN1 | calpain 1, (mu/I) large subunit | -0.00388409 |
| AREG | amphiregulin | -0.0038815 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | -0.00387244 |
| UBE2S | ubiquitin-conjugating enzyme E2S | -0.00386751 |
| CCDC81 | coiled-coil domain containing 81 | -0.00385707 |
| CNTN1 | contactin 1 | -0.00385688 |
| GNAS | GNAS complex locus | -0.00385066 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.00383006 |
| KMT5B | lysine methyltransferase 5B | -0.00382503 |
| BGN | biglycan | -0.00382476 |
| MOXD1 | monooxygenase, DBH-like 1 | -0.00381644 |
| THBS1 | thrombospondin 1 | -0.00380996 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -0.00380296 |
| FMOD | fibromodulin | -0.00380172 |
| PRR7 | proline rich 7 (synaptic) | -0.0037973 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | -0.00378833 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | -0.00378338 |
| PILRB | paired immunoglobin-like type 2 receptor beta | -0.00377733 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.00377046 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00376784 |
| ABHD6 | abhydrolase domain containing 6 | -0.0037676 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.00376396 |
| RUNX1 | runt-related transcription factor 1 | -0.00376102 |
| SIDT2 | SID1 transmembrane family, member 2 | -0.00375671 |
| RAB15 | RAB15, member RAS oncogene family | -0.00374132 |
| CEP350 | centrosomal protein 350kDa | -0.00372806 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | -0.00370455 |
| S100A9 | S100 calcium binding protein A9 | -0.00369864 |
| CTSD | cathepsin D | -0.00369518 |
| TPD52L1 | tumor protein D52-like 1 | -0.00369311 |
| LOXL1 | lysyl oxidase-like 1 | -0.00369005 |
| NPIPA1 | nuclear pore complex interacting protein family, member A1 | -0.00367438 |
| NYNRIN | NYN domain and retroviral integrase containing | -0.00367343 |
| MLPH | melanophilin | -0.00367256 |
| LDB2 | LIM domain binding 2 | -0.00367253 |
| ISYNA1 | inositol-3-phosphate synthase 1 | -0.00367 |
| TENM4 | teneurin transmembrane protein 4 | -0.00366424 |
| FBN1 | fibrillin 1 | -0.00365944 |
| KRT7 | keratin 7, type II | -0.00365611 |
| ABHD4 | abhydrolase domain containing 4 | -0.00365545 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | -0.00364966 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00364195 |
| KLK1 | kallikrein 1 | -0.00362916 |
| GRAMD2B | GRAM domain containing 2B | -0.00362692 |
| MLXIP | MLX interacting protein | -0.00360818 |
| PRTN3 | proteinase 3 | -0.00360801 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.00360385 |
| ANKRD11 | ankyrin repeat domain 11 | -0.00359413 |
| ATF5 | activating transcription factor 5 | -0.00358086 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | -0.0035644 |
| ABR | active BCR-related | -0.00356435 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.00353544 |
| LRRC32 | leucine rich repeat containing 32 | -0.00353433 |
| TNPO2 | transportin 2 | -0.00352972 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.00352831 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.003514 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.00351259 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.00351224 |
| C9ORF16 | chromosome 9 open reading frame 16 | -0.00350112 |
| DAPK3 | death-associated protein kinase 3 | -0.00349554 |
| CAPN3 | calpain 3, (p94) | -0.00349378 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | -0.00349218 |
| EML3 | echinoderm microtubule associated protein like 3 | -0.00346999 |
| NID2 | nidogen 2 (osteonidogen) | -0.0034618 |
| SMC1A | structural maintenance of chromosomes 1A | -0.00345784 |
| THAP12 | THAP domain containing 12 | -0.00345513 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.00344509 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.00344316 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.00343753 |
| CD81 | CD81 molecule | -0.00343734 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | -0.00343364 |
| TRIM28 | tripartite motif containing 28 | -0.003428 |
| PRKCZ | protein kinase C, zeta | -0.00342698 |
| ZNF331 | zinc finger protein 331 | -0.00342368 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | -0.00342095 |
| TSPAN5 | tetraspanin 5 | -0.00342063 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.00340067 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.00340017 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.00339967 |
| HOPX | HOP homeobox | -0.00339718 |
| GAB2 | GRB2-associated binding protein 2 | -0.0033933 |
| IRS1 | insulin receptor substrate 1 | -0.00339221 |
| MEIS2 | Meis homeobox 2 | -0.00337306 |
| PRMT1 | protein arginine methyltransferase 1 | -0.00337166 |
| DUSP2 | dual specificity phosphatase 2 | -0.00336919 |
| H1-0 | H1.0 linker histone | -0.00336652 |
| GATA2 | GATA binding protein 2 | -0.00336369 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | -0.00334694 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.00334307 |
| HOXC6 | homeobox C6 | -0.00334297 |
| KLK5 | kallikrein-related peptidase 5 | -0.00333764 |
| SUSD6 | sushi domain containing 6 | -0.0033369 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | -0.00333029 |
| EFHD2 | EF-hand domain family, member D2 | -0.0033277 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | -0.00332465 |
| NEO1 | neogenin 1 | -0.00332117 |
