| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | APTO-253 perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the APTO-253_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CADM2 | cell adhesion molecule 2 | 0.174723 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.167274 |
| HMGA2 | high mobility group AT-hook 2 | 0.123655 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.109019 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0826635 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0776898 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0729453 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0691342 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0647293 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0584096 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0550891 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0480942 |
| ENO1 | enolase 1, (alpha) | 0.0447003 |
| ACTG1 | actin gamma 1 | 0.0410974 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0391907 |
| EGFR | epidermal growth factor receptor | 0.0389303 |
| CTBP2 | C-terminal binding protein 2 | 0.0353648 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0344395 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0343037 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0312411 |
| MYOF | myoferlin | 0.0308718 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.029058 |
| PLS3 | plastin 3 | 0.0287819 |
| CUX1 | cut-like homeobox 1 | 0.0285101 |
| FRMD6 | FERM domain containing 6 | 0.0284592 |
| EGR1 | early growth response 1 | 0.0281698 |
| MGP | matrix Gla protein | 0.0281246 |
| KAZN | kazrin, periplakin interacting protein | 0.0272865 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0262752 |
| RSU1 | Ras suppressor protein 1 | 0.0256756 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0256216 |
| MAP1B | microtubule-associated protein 1B | 0.0256105 |
| PDE10A | phosphodiesterase 10A | 0.0255219 |
| SIK3 | SIK family kinase 3 | 0.0251584 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | 0.0248061 |
| ATP11A | ATPase, class VI, type 11A | 0.0243059 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0237924 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0235912 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0232238 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0231732 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0231359 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0229306 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0227917 |
| NBEA | neurobeachin | 0.0227722 |
| ADIPOR2 | adiponectin receptor 2 | 0.0225698 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0223013 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.022293 |
| ZFHX3 | zinc finger homeobox 3 | 0.0221621 |
| SCFD1 | sec1 family domain containing 1 | 0.0219273 |
| CDK6 | cyclin-dependent kinase 6 | 0.0217984 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0217476 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0215624 |
| SHROOM3 | shroom family member 3 | 0.0215378 |
| RAI1 | retinoic acid induced 1 | 0.0213894 |
| TMSB10 | thymosin beta 10 | 0.0207968 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0206318 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | 0.0206075 |
| PARD3B | par-3 family cell polarity regulator beta | 0.020515 |
| FLNB | filamin B, beta | 0.0201933 |
| RAD51B | RAD51 paralog B | 0.0197141 |
| DENND1A | DENN/MADD domain containing 1A | 0.0195313 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.0195002 |
| TRRAP | transformation/transcription domain-associated protein | 0.019197 |
| THBS1 | thrombospondin 1 | 0.0190296 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0190254 |
| TRIM9 | tripartite motif containing 9 | 0.0189697 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0188771 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0186137 |
| EHBP1 | EH domain binding protein 1 | 0.0184391 |
| PHF14 | PHD finger protein 14 | 0.0183098 |
| INO80 | INO80 complex subunit | 0.018194 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.018183 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0181303 |
| UBE3D | ubiquitin protein ligase E3D | 0.0181237 |
| UTRN | utrophin | 0.0180694 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0180548 |
| TOP1 | topoisomerase (DNA) I | 0.0179017 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.01774 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0176656 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0176088 |
| CLIC4 | chloride intracellular channel 4 | 0.0171108 |
| COL5A2 | collagen, type V, alpha 2 | 0.0168294 |
| HDAC8 | histone deacetylase 8 | 0.0168165 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 0.0163841 |
| POTEF | POTE ankyrin domain family, member F | 0.0163449 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0162562 |
| INTS6 | integrator complex subunit 6 | 0.0161297 |
| ACTN4 | actinin, alpha 4 | 0.0159689 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0159615 |
| VCL | vinculin | 0.0158984 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0158038 |
| FARS2 | phenylalanyl-tRNA synthetase 2, mitochondrial | 0.0157998 |
| TBC1D32 | TBC1 domain family, member 32 | 0.0155318 |
| NBEAL1 | neurobeachin-like 1 | 0.0153539 |
| MSRA | methionine sulfoxide reductase A | 0.0153374 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0153323 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0153071 |
| STXBP4 | syntaxin binding protein 4 | 0.0150413 |
| SEM1 | SEM1 26S proteasome subunit | 0.0150052 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0148595 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MEST | mesoderm specific transcript | -0.122373 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.109451 |
| ZNF292 | zinc finger protein 292 | -0.106539 |
| RPS2 | ribosomal protein S2 | -0.100178 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0957483 |
| MT2A | metallothionein 2A | -0.0934162 |
| MED13L | mediator complex subunit 13-like | -0.0779473 |
| CENPF | centromere protein F, 350/400kDa | -0.0778878 |
| QKI | QKI, KH domain containing, RNA binding | -0.0741454 |
| HMGB2 | high mobility group box 2 | -0.0715259 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0570978 |
| SBF2 | SET binding factor 2 | -0.0566885 |
| SQSTM1 | sequestosome 1 | -0.0558487 |
| PTMA | prothymosin, alpha | -0.0535546 |
| MATR3 | matrin 3 | -0.0527626 |
| ITGAV | integrin, alpha V | -0.0517636 |
| RAD21 | RAD21 homolog (S. pombe) | -0.049819 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0494934 |
| OGA | O-GlcNAcase | -0.0493182 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0483602 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.048144 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0469224 |
| ZNF608 | zinc finger protein 608 | -0.0464844 |
| GOLGA4 | golgin A4 | -0.0449058 |
| SET | SET nuclear proto-oncogene | -0.0445949 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0437833 |
| TPX2 | TPX2, microtubule-associated | -0.0424914 |
| RPS12 | ribosomal protein S12 | -0.0420132 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0420067 |
| USP3 | ubiquitin specific peptidase 3 | -0.0418934 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0417888 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0409924 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0407374 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | -0.0403525 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0401597 |
| RPL11 | ribosomal protein L11 | -0.0400249 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.039486 |
| CENPE | centromere protein E, 312kDa | -0.039144 |
| CALR | calreticulin | -0.0388517 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0386228 |
| XPO1 | exportin 1 | -0.0382029 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0379201 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0377754 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0374691 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.0366597 |
| PRRC2C | proline-rich coiled-coil 2C | -0.036655 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0366506 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0364398 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0363218 |
| RPL37 | ribosomal protein L37 | -0.0337553 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0331088 |
| BCOR | BCL6 corepressor | -0.0330083 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0327438 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.032494 |
| PAXBP1 | PAX3 and PAX7 binding protein 1 | -0.0318431 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0315659 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.03156 |
| RHEB | Ras homolog enriched in brain | -0.0315526 |
| NKTR | natural killer cell triggering receptor | -0.0314273 |
| RYBP | RING1 and YY1 binding protein | -0.0312819 |
| RLF | rearranged L-myc fusion | -0.0312359 |
| MTF2 | metal response element binding transcription factor 2 | -0.0309186 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0305406 |
| RPS18 | ribosomal protein S18 | -0.0305279 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0304478 |
| NFIA | nuclear factor I/A | -0.0304406 |
| PHIP | pleckstrin homology domain interacting protein | -0.0302193 |
| SEPTIN7 | septin 7 | -0.0301045 |
| IER3 | immediate early response 3 | -0.0300243 |
| RPL7 | ribosomal protein L7 | -0.029955 |
| CDC73 | cell division cycle 73 | -0.0296285 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0295515 |
| HOXA3 | homeobox A3 | -0.0295082 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0291477 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0290462 |
| WBP11 | WW domain binding protein 11 | -0.0289925 |
| RPS3 | ribosomal protein S3 | -0.0289525 |
| RPS27A | ribosomal protein S27a | -0.028854 |
| RACK1 | receptor for activated C kinase 1 | -0.0286864 |
| CCNL1 | cyclin L1 | -0.0286217 |
| RPS23 | ribosomal protein S23 | -0.0284549 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0283947 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0283848 |
| RPS24 | ribosomal protein S24 | -0.0282987 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | -0.028287 |
| SMAP1 | small ArfGAP 1 | -0.0279082 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0278546 |
| H1-4 | H1.4 linker histone, cluster member | -0.0278384 |
| KIF11 | kinesin family member 11 | -0.0276976 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.027654 |
| SRPK2 | SRSF protein kinase 2 | -0.0276197 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0276168 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0273057 |
| RPL37A | ribosomal protein L37a | -0.0271398 |
| ANLN | anillin, actin binding protein | -0.0270165 |
| PDGFC | platelet derived growth factor C | -0.0270039 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0269758 |
| OPTN | optineurin | -0.0269213 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0268064 |
| MKI67 | marker of proliferation Ki-67 | -0.0267039 |
