| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | APTO-253 perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the APTO-253_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FMN1 | formin 1 | 0.0872971 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0625373 |
| CDC73 | cell division cycle 73 | 0.0582667 |
| NLGN1 | neuroligin 1 | 0.056209 |
| TLE4 | transducin-like enhancer of split 4 | 0.0527726 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0500228 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0487272 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0477728 |
| CENPF | centromere protein F, 350/400kDa | 0.0466518 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0465237 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0448435 |
| ASPH | aspartate beta-hydroxylase | 0.0443735 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0420828 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0414595 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0413172 |
| VMP1 | vacuole membrane protein 1 | 0.041206 |
| TMEM178B | transmembrane protein 178B | 0.0409564 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0387136 |
| EXOC4 | exocyst complex component 4 | 0.0386411 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0379812 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0359294 |
| VCL | vinculin | 0.0350388 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0345088 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0344527 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0337209 |
| SRPK2 | SRSF protein kinase 2 | 0.0326679 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0308019 |
| RBM33 | RNA binding motif protein 33 | 0.0303281 |
| RNF145 | ring finger protein 145 | 0.0287578 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0287447 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0286357 |
| COG5 | component of oligomeric golgi complex 5 | 0.0286092 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0279885 |
| SMYD3 | SET and MYND domain containing 3 | 0.0276684 |
| ACTN1 | actinin, alpha 1 | 0.0275116 |
| PCDH7 | protocadherin 7 | 0.0273993 |
| SETBP1 | SET binding protein 1 | 0.0265144 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0256761 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0251726 |
| USP53 | ubiquitin specific peptidase 53 | 0.0251686 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.025087 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0243432 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0242719 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0240093 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0239296 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0238885 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0233809 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0230798 |
| CYTH3 | cytohesin 3 | 0.0227993 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0223764 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0221262 |
| MED13L | mediator complex subunit 13-like | 0.0220255 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0219992 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0219846 |
| QKI | QKI, KH domain containing, RNA binding | 0.0219699 |
| HELZ | helicase with zinc finger | 0.0216382 |
| CCNL1 | cyclin L1 | 0.0211326 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0210743 |
| MT2A | metallothionein 2A | 0.0207853 |
| FOSL1 | FOS-like antigen 1 | 0.0206692 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.020667 |
| SEM1 | SEM1 26S proteasome subunit | 0.020505 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.020355 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.020078 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0198788 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0194639 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0192994 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0192548 |
| AMOTL1 | angiomotin like 1 | 0.0192356 |
| MT1X | metallothionein 1X | 0.0190397 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0189223 |
| MSN | moesin | 0.0187493 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0186324 |
| NOTCH2 | notch 2 | 0.0181237 |
| RYBP | RING1 and YY1 binding protein | 0.0180188 |
| COPA | coatomer protein complex, subunit alpha | 0.0179064 |
| BSG | basigin (Ok blood group) | 0.0179019 |
| PHIP | pleckstrin homology domain interacting protein | 0.0178923 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0173222 |
| ZFP36 | ZFP36 ring finger protein | 0.0172795 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0171574 |
| EFCAB13 | EF-hand calcium binding domain 13 | 0.0171262 |
| AHR | aryl hydrocarbon receptor | 0.017109 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0170872 |
| STK24 | serine/threonine kinase 24 | 0.0170819 |
| OPHN1 | oligophrenin 1 | 0.0168311 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0167709 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0167686 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0167067 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.016692 |
| FAM3C | family with sequence similarity 3, member C | 0.0165229 |
| ZNF292 | zinc finger protein 292 | 0.0165034 |
| SCLT1 | sodium channel and clathrin linker 1 | 0.016497 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0164814 |
| TOP1 | topoisomerase (DNA) I | 0.0163519 |
| NUP58 | nucleoporin 58 | 0.016228 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0162267 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.016096 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0160705 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0160696 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.253381 |
| FN1 | fibronectin 1 | -0.207339 |
| VIM | vimentin | -0.203412 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.125064 |
| VGF | VGF nerve growth factor inducible | -0.122366 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.113973 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.113428 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.098235 |
| ACTG1 | actin gamma 1 | -0.0924269 |
| ENO1 | enolase 1, (alpha) | -0.0889374 |
| HLA-B | major histocompatibility complex, class I, B | -0.0880302 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0798587 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0793946 |
| PGK1 | phosphoglycerate kinase 1 | -0.0749929 |
| PTMA | prothymosin, alpha | -0.0592584 |
| RPL37A | ribosomal protein L37a | -0.0531617 |
| GDF15 | growth differentiation factor 15 | -0.0483278 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0482467 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0479214 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0473147 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0467705 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0467431 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0463165 |
| S100A6 | S100 calcium binding protein A6 | -0.0451032 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0449979 |
| SCFD2 | sec1 family domain containing 2 | -0.0438691 |
| CALU | calumenin | -0.0430423 |
| PLIN2 | perilipin 2 | -0.0427672 |
| RPS3 | ribosomal protein S3 | -0.0421908 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.041716 |
| NAV2 | neuron navigator 2 | -0.0413225 |
| SDC2 | syndecan 2 | -0.0399331 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0392476 |
| OXR1 | oxidation resistance 1 | -0.0380317 |
| RPLP1 | ribosomal protein, large, P1 | -0.0379757 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0379374 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.037882 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0378724 |
| RPS8 | ribosomal protein S8 | -0.0376454 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0365549 |
| FRMD4A | FERM domain containing 4A | -0.0358398 |
| HLA-A | major histocompatibility complex, class I, A | -0.0357925 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0353493 |
| CD44 | CD44 molecule (Indian blood group) | -0.0351015 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0346777 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0344666 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0342337 |
| NDRG1 | N-myc downstream regulated 1 | -0.0341319 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.0336197 |
| RPS6 | ribosomal protein S6 | -0.0335734 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0333656 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0332278 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0331162 |
| IER3 | immediate early response 3 | -0.0327779 |
| RPS27A | ribosomal protein S27a | -0.0324134 |
| TMEM123 | transmembrane protein 123 | -0.0323234 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0321179 |
| TMSB10 | thymosin beta 10 | -0.0321008 |
| CTSD | cathepsin D | -0.0315392 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0314362 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0312114 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0311551 |
| RPL35A | ribosomal protein L35a | -0.0310787 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0305638 |
| RPLP2 | ribosomal protein, large, P2 | -0.0304721 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0303306 |
| GOLGA4 | golgin A4 | -0.0303171 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0303019 |
| TNNC1 | troponin C type 1 (slow) | -0.0302807 |
| CD63 | CD63 molecule | -0.0300438 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | -0.0299565 |
| PARVB | parvin, beta | -0.0296541 |
| RPS29 | ribosomal protein S29 | -0.0296515 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0294417 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0293181 |
| OGA | O-GlcNAcase | -0.0292432 |
| RPS12 | ribosomal protein S12 | -0.0292338 |
| CANX | calnexin | -0.0291667 |
| PDE10A | phosphodiesterase 10A | -0.0286018 |
| CLMN | calmin (calponin-like, transmembrane) | -0.0283558 |
| HLA-E | major histocompatibility complex, class I, E | -0.0281628 |
| RPL26 | ribosomal protein L26 | -0.0281502 |
| UBE3C | ubiquitin protein ligase E3C | -0.027858 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0278038 |
| GSN | gelsolin | -0.0275682 |
| RRBP1 | ribosome binding protein 1 | -0.0274182 |
| CAVIN1 | caveolae associated protein 1 | -0.0272935 |
| CCND1 | cyclin D1 | -0.0271455 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.027132 |
| PLOD3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | -0.027098 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0269675 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0268614 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0266633 |
| NRCAM | neuronal cell adhesion molecule | -0.0265022 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0264423 |
| RUNX1 | runt-related transcription factor 1 | -0.0264085 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0263575 |
| JMJD1C | jumonji domain containing 1C | -0.0262397 |
| FTL | ferritin, light polypeptide | -0.026173 |
| ADAM19 | ADAM metallopeptidase domain 19 | -0.0260293 |
