| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | APTO-253 perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the APTO-253_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CP | ceruloplasmin (ferroxidase) | 0.117191 |
| MT2A | metallothionein 2A | 0.109262 |
| APOL1 | apolipoprotein L, 1 | 0.098823 |
| EFNA5 | ephrin-A5 | 0.0985547 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.095459 |
| RAD51B | RAD51 paralog B | 0.0903507 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0763036 |
| RNF213 | ring finger protein 213 | 0.0669581 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0668013 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0648911 |
| LCN2 | lipocalin 2 | 0.0634868 |
| TGM2 | transglutaminase 2 | 0.0629764 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0625647 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0582581 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0576388 |
| NRG3 | neuregulin 3 | 0.0534432 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0529582 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0528738 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0526266 |
| ENO1 | enolase 1, (alpha) | 0.052323 |
| B2M | beta-2-microglobulin | 0.050549 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0502511 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0498908 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0480824 |
| MX1 | MX dynamin-like GTPase 1 | 0.0435285 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0433226 |
| PCDH7 | protocadherin 7 | 0.0427745 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0425502 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.0421506 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.042146 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.040376 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0403206 |
| SP100 | SP100 nuclear antigen | 0.0400972 |
| MX2 | MX dynamin-like GTPase 2 | 0.0393227 |
| HDAC9 | histone deacetylase 9 | 0.039243 |
| EGR1 | early growth response 1 | 0.0391737 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0391492 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0386389 |
| TMC5 | transmembrane channel-like 5 | 0.0384459 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0382023 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0368477 |
| EXT1 | exostosin glycosyltransferase 1 | 0.036232 |
| PLAT | plasminogen activator, tissue | 0.0357419 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0354203 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.034995 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0343949 |
| CMIP | c-Maf inducing protein | 0.0343469 |
| KRT19 | keratin 19, type I | 0.0330914 |
| HLA-B | major histocompatibility complex, class I, B | 0.032764 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0324944 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0323988 |
| ST8SIA6 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 | 0.0321818 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0320885 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0320806 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0312431 |
| C3 | complement component 3 | 0.0312312 |
| NABP1 | nucleic acid binding protein 1 | 0.0309405 |
| ATXN1 | ataxin 1 | 0.0302706 |
| PMP22 | peripheral myelin protein 22 | 0.0301272 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0290869 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.028822 |
| IFI44L | interferon-induced protein 44-like | 0.0271899 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0270158 |
| PKM | pyruvate kinase, muscle | 0.0264637 |
| KYNU | kynureninase | 0.0261506 |
| ANXA4 | annexin A4 | 0.0260118 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0259786 |
| EGFR | epidermal growth factor receptor | 0.0256685 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0254042 |
| DNAH11 | dynein, axonemal, heavy chain 11 | 0.024925 |
| BPTF | bromodomain PHD finger transcription factor | 0.0246231 |
| CFB | complement factor B | 0.0245217 |
| MCL1 | myeloid cell leukemia 1 | 0.024477 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0242599 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0240892 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0237606 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0237503 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0237496 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0233985 |
| INTS6 | integrator complex subunit 6 | 0.0231533 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0231335 |
| SMAD3 | SMAD family member 3 | 0.0229446 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0229229 |
| RIGI | RNA sensor RIG-I | 0.0228183 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0226509 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0220852 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0219326 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0218098 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.021777 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0217225 |
| EHBP1 | EH domain binding protein 1 | 0.0217225 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0213337 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0212728 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0211685 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 0.0208993 |
| NCKAP5 | NCK-associated protein 5 | 0.0208488 |
| TXNIP | thioredoxin interacting protein | 0.0207799 |
| EXOC4 | exocyst complex component 4 | 0.0207764 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0206245 |
| MYO1E | myosin IE | 0.0205781 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.145082 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.121255 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.116108 |
| SPAG9 | sperm associated antigen 9 | -0.110651 |
| TSC22D2 | TSC22 domain family, member 2 | -0.104859 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0880642 |
| PLAU | plasminogen activator, urokinase | -0.0776745 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0762421 |
| RBM39 | RNA binding motif protein 39 | -0.0719957 |
| ACTG1 | actin gamma 1 | -0.0694122 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0677042 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0676246 |
| PTMA | prothymosin, alpha | -0.0653927 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0637657 |
| ANXA2 | annexin A2 | -0.0635784 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0627874 |
| PGK1 | phosphoglycerate kinase 1 | -0.0604939 |
| RTN4 | reticulon 4 | -0.0603184 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0602959 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0564372 |
| OGA | O-GlcNAcase | -0.0564341 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0561322 |
| TMSB4X | thymosin beta 4, X-linked | -0.0557671 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.055641 |
| FAM13A | family with sequence similarity 13, member A | -0.0547119 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.052163 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0508999 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.050028 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0476465 |
| RLF | rearranged L-myc fusion | -0.0475678 |
| UBC | ubiquitin C | -0.0465888 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0454336 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0451294 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0429129 |
| TOP1 | topoisomerase (DNA) I | -0.0424791 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0420972 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0415674 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0407836 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0404688 |
| CANX | calnexin | -0.040389 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0401551 |
| LAMB3 | laminin, beta 3 | -0.0396638 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0395851 |
| ABI1 | abl-interactor 1 | -0.0395736 |
| FNBP1L | formin binding protein 1-like | -0.0393883 |
| CDC73 | cell division cycle 73 | -0.0392376 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0390908 |
| HELZ | helicase with zinc finger | -0.0385148 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0373066 |
| ATP11B | ATPase, class VI, type 11B | -0.0371747 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0368601 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0364035 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0362202 |
| EZR | ezrin | -0.0358477 |
| HMGA1 | high mobility group AT-hook 1 | -0.03557 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0353146 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0350583 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0348571 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0347413 |
| TFG | TRK-fused gene | -0.0345473 |
| EREG | epiregulin | -0.0345162 |
| USP3 | ubiquitin specific peptidase 3 | -0.0344892 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0343433 |
| FAM162A | family with sequence similarity 162, member A | -0.0342778 |
| MATR3 | matrin 3 | -0.0342574 |
| NEK7 | NIMA-related kinase 7 | -0.0341824 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0341282 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0335665 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0331682 |
| SUCO | SUN domain containing ossification factor | -0.0325921 |
| NUP58 | nucleoporin 58 | -0.0325837 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0324295 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0324074 |
| TMEM123 | transmembrane protein 123 | -0.0321372 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0318742 |
| PLAUR | plasminogen activator, urokinase receptor | -0.03186 |
| YTHDC1 | YTH domain containing 1 | -0.0318122 |
| FLNB | filamin B, beta | -0.0317569 |
| TMSB10 | thymosin beta 10 | -0.0316275 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0315844 |
| RASA2 | RAS p21 protein activator 2 | -0.0313049 |
| OSBPL9 | oxysterol binding protein-like 9 | -0.0311864 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.030757 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0305132 |
| KLF6 | Kruppel-like factor 6 | -0.030474 |
| CCNL1 | cyclin L1 | -0.0301719 |
| MORF4L2 | mortality factor 4 like 2 | -0.0301204 |
| ZNF292 | zinc finger protein 292 | -0.0300812 |
| CCNY | cyclin Y | -0.0297934 |
| LDHA | lactate dehydrogenase A | -0.0296565 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0293404 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0292338 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0290742 |
| IRF6 | interferon regulatory factor 6 | -0.0289097 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0286754 |
| AHNAK | AHNAK nucleoprotein | -0.0286598 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0285822 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0284656 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.0284419 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0284362 |
