| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | APTO-253 perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the APTO-253_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.185484 |
| VCL | vinculin | 0.0679071 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0583828 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0557123 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0555243 |
| PTMA | prothymosin, alpha | 0.0544472 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0539335 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0536609 |
| COL1A1 | collagen, type I, alpha 1 | 0.0535525 |
| CRH | corticotropin releasing hormone | 0.0532734 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.05318 |
| GLCCI1 | glucocorticoid induced 1 | 0.0511069 |
| PLPP1 | phospholipid phosphatase 1 | 0.0506107 |
| RPL23 | ribosomal protein L23 | 0.0499344 |
| TLE4 | transducin-like enhancer of split 4 | 0.0459591 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0406763 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0365888 |
| MAP1B | microtubule-associated protein 1B | 0.0361696 |
| VIM | vimentin | 0.0353008 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0341966 |
| FERMT2 | fermitin family member 2 | 0.0339025 |
| STK38L | serine/threonine kinase 38 like | 0.0332687 |
| RPS6 | ribosomal protein S6 | 0.0330868 |
| EGR1 | early growth response 1 | 0.0326329 |
| SYT1 | synaptotagmin I | 0.0315484 |
| ENO1 | enolase 1, (alpha) | 0.0296736 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0290287 |
| RPL34 | ribosomal protein L34 | 0.0288886 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0288011 |
| MED13L | mediator complex subunit 13-like | 0.028746 |
| MEIS2 | Meis homeobox 2 | 0.0276474 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0269733 |
| HOMER1 | homer scaffolding protein 1 | 0.0262961 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0261425 |
| PHOX2B | paired-like homeobox 2b | 0.0260105 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0257982 |
| CPNE8 | copine VIII | 0.0254537 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.0249075 |
| FAM107B | family with sequence similarity 107, member B | 0.0246971 |
| CBX3 | chromobox homolog 3 | 0.0246843 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0234516 |
| FTL | ferritin, light polypeptide | 0.02319 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0230566 |
| GATA3 | GATA binding protein 3 | 0.0229595 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0229117 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0229054 |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) | 0.0228576 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0228505 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0227242 |
| PKM | pyruvate kinase, muscle | 0.0222099 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.0220923 |
| MAP4 | microtubule-associated protein 4 | 0.0216277 |
| SYNPO2 | synaptopodin 2 | 0.0214644 |
| MYO1E | myosin IE | 0.0212362 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0211081 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0208826 |
| PCDH17 | protocadherin 17 | 0.0207845 |
| SIK2 | salt-inducible kinase 2 | 0.020735 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0207168 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0205176 |
| ITGA1 | integrin, alpha 1 | 0.0202451 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0200608 |
| H1-0 | H1.0 linker histone | 0.020017 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0199785 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0196714 |
| RPS23 | ribosomal protein S23 | 0.0195599 |
| S100A9 | S100 calcium binding protein A9 | 0.0194523 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0194114 |
| RPL36 | ribosomal protein L36 | 0.0191191 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0190963 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0189705 |
| BTBD7 | BTB (POZ) domain containing 7 | 0.0188284 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.0187447 |
| RPL27 | ribosomal protein L27 | 0.0186215 |
| SEPTIN7 | septin 7 | 0.0186 |
| MX2 | MX dynamin-like GTPase 2 | 0.0185745 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited | 0.0182143 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0180098 |
| RPL19 | ribosomal protein L19 | 0.0179463 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0179079 |
| PDE7A | phosphodiesterase 7A | 0.017833 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | 0.0175772 |
| CXXC5 | CXXC finger protein 5 | 0.0174768 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0174428 |
| REXO2 | RNA exonuclease 2 | 0.017297 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0171649 |
| RCOR1 | REST corepressor 1 | 0.0171529 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0170284 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0170224 |
| IER3 | immediate early response 3 | 0.0169814 |
| DGKH | diacylglycerol kinase, eta | 0.0169669 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0169294 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0168242 |
| PDE10A | phosphodiesterase 10A | 0.0166834 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 0.0166019 |
| B2M | beta-2-microglobulin | 0.0164377 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 0.0162733 |
| BPTF | bromodomain PHD finger transcription factor | 0.0160163 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0157678 |
| TBX2 | T-box 2 | 0.0156096 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.143758 |
| PLAT | plasminogen activator, tissue | -0.0751589 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0702957 |
| SPAG9 | sperm associated antigen 9 | -0.0547145 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0513854 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0505416 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0487665 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0475386 |
| RPL38 | ribosomal protein L38 | -0.0461236 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0459632 |
| LPIN1 | lipin 1 | -0.0452793 |
| TRIB2 | tribbles pseudokinase 2 | -0.0440621 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0434786 |
| LSAMP | limbic system-associated membrane protein | -0.0430868 |
| FMN1 | formin 1 | -0.042851 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0411225 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0398374 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0394135 |
| SEPTIN9 | septin 9 | -0.0392744 |
| SMAD3 | SMAD family member 3 | -0.0388511 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0388396 |
| FRMD4A | FERM domain containing 4A | -0.0386976 |
| CEP95 | centrosomal protein 95kDa | -0.0382356 |
| WDR26 | WD repeat domain 26 | -0.0377896 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0364918 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0349025 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0346206 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0344327 |
| KLHL13 | kelch-like family member 13 | -0.0337814 |
| AUTS2 | autism susceptibility candidate 2 | -0.0337674 |
| AHNAK | AHNAK nucleoprotein | -0.0331419 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0327254 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0315743 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.031296 |
| COL3A1 | collagen, type III, alpha 1 | -0.0311696 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0305613 |
| MSI2 | musashi RNA-binding protein 2 | -0.0303293 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0303121 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0300335 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0299513 |
| PHF3 | PHD finger protein 3 | -0.0296247 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0293739 |
| MYO6 | myosin VI | -0.0293471 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0288984 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0283729 |
| CEP170 | centrosomal protein 170kDa | -0.0281485 |
| SQSTM1 | sequestosome 1 | -0.0280136 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0277651 |
| KCNT2 | potassium channel, sodium activated subfamily T, member 2 | -0.0275586 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0273807 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0273128 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0273093 |
| GPC5 | glypican 5 | -0.0272612 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0272094 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0267392 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0267018 |
| RPS17 | ribosomal protein S17 | -0.0266459 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0265821 |
| ATXN10 | ataxin 10 | -0.0265561 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0263919 |
| SSBP3 | single stranded DNA binding protein 3 | -0.0262053 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0260824 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0260047 |
| RBM20 | RNA binding motif protein 20 | -0.0257378 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0255866 |
| SBF2 | SET binding factor 2 | -0.0254988 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0254328 |
| AHR | aryl hydrocarbon receptor | -0.0254182 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0252643 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0249895 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | -0.02489 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0248866 |
| HELZ | helicase with zinc finger | -0.0246171 |
| CLTC | clathrin, heavy chain (Hc) | -0.0243243 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0242448 |
| ANO6 | anoctamin 6 | -0.0238705 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | -0.0238061 |
| MTDH | metadherin | -0.0236808 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0236565 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.023421 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0233873 |
| RTN4 | reticulon 4 | -0.023334 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0232735 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0227986 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0227379 |
| PCBP3 | poly(rC) binding protein 3 | -0.0222627 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0222324 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0221746 |
| CANX | calnexin | -0.0221108 |
| GOLGA4 | golgin A4 | -0.0218828 |
| VMP1 | vacuole membrane protein 1 | -0.0218183 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0217197 |
| WDR33 | WD repeat domain 33 | -0.0216619 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0215516 |
| HPCAL1 | hippocalcin-like 1 | -0.0214589 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0211512 |
| RPL12 | ribosomal protein L12 | -0.0209767 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0209179 |
| CTSB | cathepsin B | -0.020746 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0206296 |
