| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | APTO-253 perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the APTO-253_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.126101 |
| LMO7 | LIM domain 7 | 0.120812 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.105793 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0899644 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0839958 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0816222 |
| TXNIP | thioredoxin interacting protein | 0.0781659 |
| NDRG1 | N-myc downstream regulated 1 | 0.0729003 |
| RIGI | RNA sensor RIG-I | 0.0727558 |
| RPS19 | ribosomal protein S19 | 0.070375 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0592851 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0589413 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0588371 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0561302 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0535748 |
| PHF3 | PHD finger protein 3 | 0.0530847 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0520378 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0513501 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0510729 |
| RPS21 | ribosomal protein S21 | 0.0507077 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0500035 |
| HLA-B | major histocompatibility complex, class I, B | 0.0495122 |
| CDK13 | cyclin-dependent kinase 13 | 0.0491724 |
| MUC16 | mucin 16, cell surface associated | 0.0484539 |
| B2M | beta-2-microglobulin | 0.0472881 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0472511 |
| MT2A | metallothionein 2A | 0.0472165 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0470672 |
| SDC4 | syndecan 4 | 0.0463285 |
| MYOF | myoferlin | 0.0444452 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0439684 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0438435 |
| RPS3 | ribosomal protein S3 | 0.0434945 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0428101 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0426638 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0423809 |
| RPS25 | ribosomal protein S25 | 0.0417473 |
| APP | amyloid beta (A4) precursor protein | 0.0416971 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0409836 |
| AFAP1 | actin filament associated protein 1 | 0.0404802 |
| ZNF638 | zinc finger protein 638 | 0.0401225 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0397507 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0396664 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0394772 |
| NUMB | numb homolog (Drosophila) | 0.0392408 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0389626 |
| RPL34 | ribosomal protein L34 | 0.0382344 |
| RPL19 | ribosomal protein L19 | 0.0376259 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0374584 |
| TMEM165 | transmembrane protein 165 | 0.0373776 |
| TMF1 | TATA element modulatory factor 1 | 0.0371814 |
| SP100 | SP100 nuclear antigen | 0.0365239 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0365004 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0362384 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0362006 |
| HLA-A | major histocompatibility complex, class I, A | 0.0358822 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0358158 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0354679 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.0354633 |
| IGF1R | insulin-like growth factor 1 receptor | 0.03506 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0349586 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0341188 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0340855 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.034081 |
| FNDC3B | fibronectin type III domain containing 3B | 0.034027 |
| PKM | pyruvate kinase, muscle | 0.0338296 |
| WDR7 | WD repeat domain 7 | 0.0337767 |
| AK1 | adenylate kinase 1 | 0.03358 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0335614 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0333099 |
| OGA | O-GlcNAcase | 0.033234 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0327238 |
| KRT19 | keratin 19, type I | 0.03258 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.032395 |
| LIMA1 | LIM domain and actin binding 1 | 0.032314 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0321496 |
| EZR | ezrin | 0.032133 |
| NKTR | natural killer cell triggering receptor | 0.0313356 |
| METTL15 | methyltransferase like 15 | 0.0312595 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0311265 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0310977 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0310027 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0309442 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0308508 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0308095 |
| YTHDC1 | YTH domain containing 1 | 0.0307715 |
| GNAS | GNAS complex locus | 0.0307336 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0306841 |
| USP34 | ubiquitin specific peptidase 34 | 0.029997 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.029868 |
| GLCCI1 | glucocorticoid induced 1 | 0.0298634 |
| RPLP0 | ribosomal protein, large, P0 | 0.029834 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0298162 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0295303 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0293814 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0293144 |
| BRD2 | bromodomain containing 2 | 0.0292754 |
| SRPK2 | SRSF protein kinase 2 | 0.0287794 |
| TPI1 | triosephosphate isomerase 1 | 0.028749 |
| MEIS2 | Meis homeobox 2 | 0.0284804 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0730877 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0708212 |
| GPC6 | glypican 6 | -0.0701457 |
| SPAG9 | sperm associated antigen 9 | -0.06897 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0648786 |
| FN1 | fibronectin 1 | -0.0647579 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0645245 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0642727 |
| TXNRD1 | thioredoxin reductase 1 | -0.059422 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0582347 |
| INHBA | inhibin, beta A | -0.0577329 |
| VMP1 | vacuole membrane protein 1 | -0.0575509 |
| COL6A3 | collagen, type VI, alpha 3 | -0.057207 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0568317 |
| PARD3 | par-3 family cell polarity regulator | -0.0555004 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0554922 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0542481 |
| RNF145 | ring finger protein 145 | -0.053212 |
| MSN | moesin | -0.0531599 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0509238 |
| LSAMP | limbic system-associated membrane protein | -0.0508479 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0492199 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0486526 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0479052 |
| CDC73 | cell division cycle 73 | -0.0475954 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0475259 |
| STC1 | stanniocalcin 1 | -0.0452961 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0449139 |
| ANXA2 | annexin A2 | -0.0432722 |
| SETD5 | SET domain containing 5 | -0.04259 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0407466 |
| POTEF | POTE ankyrin domain family, member F | -0.0404862 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0400298 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0395905 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0394074 |
| MMP1 | matrix metallopeptidase 1 | -0.0389331 |
| NPC1 | Niemann-Pick disease, type C1 | -0.038666 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0382311 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0379447 |
| FNBP4 | formin binding protein 4 | -0.0374203 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0371488 |
| NBAS | neuroblastoma amplified sequence | -0.0371102 |
| HDLBP | high density lipoprotein binding protein | -0.0364796 |
| FAM13A | family with sequence similarity 13, member A | -0.0364453 |
| NAV1 | neuron navigator 1 | -0.0359969 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.035859 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0357558 |
| FRMD6 | FERM domain containing 6 | -0.0356912 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0354662 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0354221 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0349362 |
| FMNL2 | formin-like 2 | -0.0348737 |
| RLF | rearranged L-myc fusion | -0.03474 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0343448 |
| PGK1 | phosphoglycerate kinase 1 | -0.0341495 |
| RUNX1 | runt-related transcription factor 1 | -0.0340717 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0339883 |
| QKI | QKI, KH domain containing, RNA binding | -0.0339595 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0333912 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0329729 |
| PRELID2 | PRELI domain containing 2 | -0.0325757 |
| TPR | translocated promoter region, nuclear basket protein | -0.0324697 |
| KLHL24 | kelch-like family member 24 | -0.0323706 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0323656 |
| SEPTIN9 | septin 9 | -0.0323175 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0319941 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0317132 |
| XPO1 | exportin 1 | -0.03137 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0313463 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0312778 |
| TJP1 | tight junction protein 1 | -0.0310414 |
| RBM39 | RNA binding motif protein 39 | -0.0308719 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0308327 |
| LAMC2 | laminin, gamma 2 | -0.0306053 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0305708 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0304657 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0299666 |
| CDC27 | cell division cycle 27 | -0.0296968 |
| EGR1 | early growth response 1 | -0.0292419 |
| RPL31 | ribosomal protein L31 | -0.0291932 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0291085 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0289836 |
| TMEM41B | transmembrane protein 41B | -0.0289031 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0288981 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0287988 |
| SBF2 | SET binding factor 2 | -0.0287763 |
| MXD1 | MAX dimerization protein 1 | -0.0287622 |
| TPM3 | tropomyosin 3 | -0.0285198 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.028278 |
| ZXDC | ZXD family zinc finger C | -0.0281988 |
| CUX1 | cut-like homeobox 1 | -0.0280685 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0280172 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0278461 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0277663 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0276689 |
| MED13L | mediator complex subunit 13-like | -0.0276423 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0276062 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0274881 |
| OSMR | oncostatin M receptor | -0.0274497 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0274339 |
