| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | APTO-253 perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the APTO-253_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.092179 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0858823 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0836678 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0751204 |
| COL5A1 | collagen, type V, alpha 1 | 0.0630355 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0611721 |
| MAP1B | microtubule-associated protein 1B | 0.0575287 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0574028 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0568615 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0545608 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0524446 |
| FN1 | fibronectin 1 | 0.0503529 |
| KYNU | kynureninase | 0.0485446 |
| IL6ST | interleukin 6 signal transducer | 0.0474249 |
| ENO1 | enolase 1, (alpha) | 0.0470982 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0467098 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0456924 |
| POTEF | POTE ankyrin domain family, member F | 0.0452136 |
| RUNX1 | runt-related transcription factor 1 | 0.0445235 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0441962 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0420182 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0418859 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0402882 |
| NAV1 | neuron navigator 1 | 0.0402794 |
| SETBP1 | SET binding protein 1 | 0.0393703 |
| PRELID2 | PRELI domain containing 2 | 0.0378036 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0370907 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0363193 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0360702 |
| EXOC4 | exocyst complex component 4 | 0.0359045 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0357678 |
| ANLN | anillin, actin binding protein | 0.0356665 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0350259 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0346594 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0323835 |
| NBAS | neuroblastoma amplified sequence | 0.0321567 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0312792 |
| ATXN1 | ataxin 1 | 0.031138 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0311368 |
| NAV2 | neuron navigator 2 | 0.0308526 |
| ASPH | aspartate beta-hydroxylase | 0.0306844 |
| VCL | vinculin | 0.0306177 |
| FLNA | filamin A, alpha | 0.0303682 |
| GLIS3 | GLIS family zinc finger 3 | 0.0303397 |
| VEGFC | vascular endothelial growth factor C | 0.0301872 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0296865 |
| NCOR2 | nuclear receptor corepressor 2 | 0.029075 |
| CDH13 | cadherin 13 | 0.0286552 |
| AHR | aryl hydrocarbon receptor | 0.0286078 |
| TNS3 | tensin 3 | 0.0285094 |
| FNIP1 | folliculin interacting protein 1 | 0.0283987 |
| IL6 | interleukin 6 | 0.0283547 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0280396 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0280199 |
| MYOF | myoferlin | 0.0274285 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0269869 |
| LAMB1 | laminin, beta 1 | 0.0267092 |
| TPM3 | tropomyosin 3 | 0.0266686 |
| NECTIN3 | nectin cell adhesion molecule 3 | 0.0264661 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0263022 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0257072 |
| SEPTIN11 | septin 11 | 0.0247463 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0243266 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.024221 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0241906 |
| NRXN3 | neurexin 3 | 0.024175 |
| SBF2 | SET binding factor 2 | 0.0241314 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0238491 |
| MSN | moesin | 0.0235207 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0234803 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0233718 |
| DST | dystonin | 0.0232082 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0231282 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0231123 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0222998 |
| PALLD | palladin, cytoskeletal associated protein | 0.0219786 |
| CD44 | CD44 molecule (Indian blood group) | 0.0218981 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0218979 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0217784 |
| SEPTIN9 | septin 9 | 0.0216681 |
| HDLBP | high density lipoprotein binding protein | 0.021641 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0214738 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0213169 |
| QKI | QKI, KH domain containing, RNA binding | 0.0212924 |
| EGFR | epidermal growth factor receptor | 0.0212798 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.021185 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0211527 |
| HDAC9 | histone deacetylase 9 | 0.0210822 |
| FBN1 | fibrillin 1 | 0.0210386 |
| PCDHGA2 | protocadherin gamma subfamily A, 2 | 0.0210016 |
| SEC24D | SEC24 family member D | 0.0209494 |
| MTREX | Mtr4 exosome RNA helicase | 0.0208565 |
| NOTCH2 | notch 2 | 0.0206505 |
| SMYD3 | SET and MYND domain containing 3 | 0.0206316 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0205611 |
| ACTG1 | actin gamma 1 | 0.0205496 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0204954 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0203822 |
| OSMR | oncostatin M receptor | 0.0202047 |
| PLCB4 | phospholipase C, beta 4 | 0.0201358 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.223081 |
| HLA-B | major histocompatibility complex, class I, B | -0.111294 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.108338 |
| VIM | vimentin | -0.0946201 |
| TMSB10 | thymosin beta 10 | -0.070733 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0687006 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0668083 |
| STC1 | stanniocalcin 1 | -0.0663823 |
| OGA | O-GlcNAcase | -0.0641869 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0621831 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0571214 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0553512 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.048746 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0454338 |
| FTL | ferritin, light polypeptide | -0.0448374 |
| RPLP1 | ribosomal protein, large, P1 | -0.0444508 |
| B2M | beta-2-microglobulin | -0.0441952 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0436466 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0436428 |
| COL1A2 | collagen, type I, alpha 2 | -0.041248 |
| HLA-A | major histocompatibility complex, class I, A | -0.0402151 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0392422 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0383213 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0381038 |
| ADM | adrenomedullin | -0.0366099 |
| H3-3B | H3.3 histone B | -0.0364687 |
| GOLGA4 | golgin A4 | -0.0364157 |
| FAM13A | family with sequence similarity 13, member A | -0.0359503 |
| NDRG1 | N-myc downstream regulated 1 | -0.0348387 |
| RPS6 | ribosomal protein S6 | -0.0347883 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0335613 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.033526 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.033316 |
| RPL37A | ribosomal protein L37a | -0.0329696 |
| RPL35A | ribosomal protein L35a | -0.0329151 |
| CADM1 | cell adhesion molecule 1 | -0.0327334 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0305885 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0305583 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0304457 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0297711 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0294285 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0293155 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0289225 |
| IKBIP | IKBKB interacting protein | -0.028856 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0287628 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0287406 |
| RPS23 | ribosomal protein S23 | -0.0281363 |
| RPS8 | ribosomal protein S8 | -0.0278855 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0274266 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0271166 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0266396 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0263533 |
| RPL23 | ribosomal protein L23 | -0.0261867 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0260181 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0258385 |
| S100A6 | S100 calcium binding protein A6 | -0.0258379 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0254819 |
| GLG1 | golgi glycoprotein 1 | -0.0254072 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0250374 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0249194 |
| CLINT1 | clathrin interactor 1 | -0.0248594 |
| HM13 | histocompatibility (minor) 13 | -0.0247055 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0244381 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0244133 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0240547 |
| ECE1 | endothelin converting enzyme 1 | -0.024012 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0239302 |
| USP3 | ubiquitin specific peptidase 3 | -0.0239173 |
| RTN4 | reticulon 4 | -0.0237306 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0234882 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0234673 |
| TGFB1 | transforming growth factor, beta 1 | -0.0230934 |
| RLF | rearranged L-myc fusion | -0.023045 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0229479 |
| RRBP1 | ribosome binding protein 1 | -0.0226822 |
| PDE10A | phosphodiesterase 10A | -0.0226652 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.022603 |
| SRP54 | signal recognition particle 54kDa | -0.0225956 |
| POMP | proteasome maturation protein | -0.0220671 |
| CAVIN1 | caveolae associated protein 1 | -0.0218623 |
| RPL31 | ribosomal protein L31 | -0.0215989 |
| KAZN | kazrin, periplakin interacting protein | -0.0212692 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.021184 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.020919 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0208222 |
| RPS12 | ribosomal protein S12 | -0.0207717 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0204509 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0204241 |
| ANXA5 | annexin A5 | -0.0202382 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0202155 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0201709 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0199982 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0199441 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0198972 |
| RPLP2 | ribosomal protein, large, P2 | -0.0198742 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0198575 |
| LAMB3 | laminin, beta 3 | -0.0198152 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0197864 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.0197795 |
| TMEM165 | transmembrane protein 165 | -0.0196796 |
