| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | APTO-253 perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the APTO-253_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD44 | CD44 molecule (Indian blood group) | 0.057214 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0552393 |
| DST | dystonin | 0.047771 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0467758 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0461881 |
| DSCAM | Down syndrome cell adhesion molecule | 0.044119 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0420705 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0416104 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0364386 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0325882 |
| SMAD3 | SMAD family member 3 | 0.0322606 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0316005 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0314197 |
| SVIL | supervillin | 0.0304515 |
| TXNRD1 | thioredoxin reductase 1 | 0.0272351 |
| CWF19L2 | CWF19-like 2, cell cycle control (S. pombe) | 0.0267237 |
| ZNF292 | zinc finger protein 292 | 0.0261328 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0248834 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0246431 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0245886 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0240672 |
| ATXN1 | ataxin 1 | 0.0238719 |
| RASAL2 | RAS protein activator like 2 | 0.0237854 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | 0.02323 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0229618 |
| FAM3C | family with sequence similarity 3, member C | 0.0224317 |
| RTN4 | reticulon 4 | 0.0224113 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0222072 |
| RAD50 | RAD50 homolog (S. cerevisiae) | 0.0218701 |
| TXNIP | thioredoxin interacting protein | 0.0218264 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0216524 |
| KIF5B | kinesin family member 5B | 0.0216026 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0215002 |
| PRR16 | proline rich 16 | 0.0208831 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0207342 |
| SET | SET nuclear proto-oncogene | 0.0206063 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0199123 |
| PHF3 | PHD finger protein 3 | 0.0198426 |
| JMJD1C | jumonji domain containing 1C | 0.0195028 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0193355 |
| EFNA5 | ephrin-A5 | 0.0192823 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0189031 |
| RDX | radixin | 0.0188967 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0187727 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0187148 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0185816 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0185626 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0184581 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0179887 |
| RSF1 | remodeling and spacing factor 1 | 0.0179694 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0179004 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0171447 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0170634 |
| EHBP1 | EH domain binding protein 1 | 0.0167101 |
| AK1 | adenylate kinase 1 | 0.0166325 |
| YY1 | YY1 transcription factor | 0.0165925 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0165303 |
| GSK3B | glycogen synthase kinase 3 beta | 0.016425 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | 0.0163418 |
| GLCCI1 | glucocorticoid induced 1 | 0.0162752 |
| MYOF | myoferlin | 0.0162491 |
| KLF12 | Kruppel-like factor 12 | 0.0161373 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0157076 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0156891 |
| PPHLN1 | periphilin 1 | 0.0156665 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0155711 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0155699 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.015512 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0155009 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0154916 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0152987 |
| THBS1 | thrombospondin 1 | 0.0152872 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0152519 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0152448 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | 0.0150511 |
| ANKRD28 | ankyrin repeat domain 28 | 0.015025 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.0149107 |
| FLNB | filamin B, beta | 0.0148208 |
| WWOX | WW domain containing oxidoreductase | 0.0147119 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0146124 |
| TMF1 | TATA element modulatory factor 1 | 0.014568 |
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 0.014527 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.014454 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0144426 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0144186 |
| CCDC93 | coiled-coil domain containing 93 | 0.0144147 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.0142843 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.014211 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0141421 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0140219 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.013987 |
| ZZZ3 | zinc finger, ZZ-type containing 3 | 0.0138516 |
| USP8 | ubiquitin specific peptidase 8 | 0.0137918 |
| CFH | complement factor H | 0.0137577 |
| C1D | C1D nuclear receptor corepressor | 0.0137349 |
| RORA | RAR-related orphan receptor A | 0.0136844 |
| KIAA0232 | KIAA0232 | 0.0136273 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0135752 |
| LIPH | lipase, member H | 0.0134021 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0132802 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.100366 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0901838 |
| PTMA | prothymosin, alpha | -0.0894548 |
| TMSB10 | thymosin beta 10 | -0.0726481 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0644105 |
| RPLP1 | ribosomal protein, large, P1 | -0.0498114 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0487206 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0479684 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.047407 |
| RPL31 | ribosomal protein L31 | -0.0446313 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0441025 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0425194 |
| RPL37A | ribosomal protein L37a | -0.0411949 |
| GNAS | GNAS complex locus | -0.0411885 |
| RPL35A | ribosomal protein L35a | -0.0388634 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0386776 |
| RPL23 | ribosomal protein L23 | -0.0378539 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0357825 |
| IER3 | immediate early response 3 | -0.0352076 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0344495 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0343029 |
| MT2A | metallothionein 2A | -0.0338988 |
| LDHA | lactate dehydrogenase A | -0.0338171 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0333293 |
| RPL37 | ribosomal protein L37 | -0.0328798 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0328661 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0325254 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0316295 |
| HMGA1 | high mobility group AT-hook 1 | -0.0315199 |
| RPS23 | ribosomal protein S23 | -0.0312224 |
| RPS8 | ribosomal protein S8 | -0.0310692 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0310264 |
| RPS6 | ribosomal protein S6 | -0.0309176 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.030678 |
| RPL19 | ribosomal protein L19 | -0.0306343 |
| RAI14 | retinoic acid induced 14 | -0.0298847 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0286133 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0285896 |
| ANGPTL4 | angiopoietin-like 4 | -0.0285255 |
| HLA-B | major histocompatibility complex, class I, B | -0.0284384 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0280862 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0280134 |
| TAOK3 | TAO kinase 3 | -0.0274851 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0264661 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0263461 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0259022 |
| MCL1 | myeloid cell leukemia 1 | -0.0257029 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0255547 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0254611 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0254418 |
| RPS17 | ribosomal protein S17 | -0.0253979 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0253292 |
| SETD5 | SET domain containing 5 | -0.0253023 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0250759 |
| EGR1 | early growth response 1 | -0.024931 |
| RPS25 | ribosomal protein S25 | -0.0248113 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0247582 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0246939 |
| NUP58 | nucleoporin 58 | -0.0243632 |
| RPS21 | ribosomal protein S21 | -0.0243446 |
| RPL36 | ribosomal protein L36 | -0.024237 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0235803 |
| AOPEP | aminopeptidase O (putative) | -0.0234356 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0230784 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0229753 |
| S100A9 | S100 calcium binding protein A9 | -0.0227092 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0226521 |
| RPS3 | ribosomal protein S3 | -0.022626 |
| BTN3A3 | butyrophilin, subfamily 3, member A3 | -0.022537 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0224513 |
| RCOR1 | REST corepressor 1 | -0.0223567 |
| H3-3B | H3.3 histone B | -0.0220982 |
| SCFD1 | sec1 family domain containing 1 | -0.0220979 |
| RPS20 | ribosomal protein S20 | -0.0217473 |
| HLA-A | major histocompatibility complex, class I, A | -0.0216361 |
| SRP54 | signal recognition particle 54kDa | -0.0214541 |
| CUL3 | cullin 3 | -0.0213864 |
| GDI2 | GDP dissociation inhibitor 2 | -0.0213635 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0211587 |
| ZBTB10 | zinc finger and BTB domain containing 10 | -0.0211552 |
| TRAF3 | TNF receptor-associated factor 3 | -0.0211523 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0211201 |
| SRPK2 | SRSF protein kinase 2 | -0.0210276 |
| ATF4 | activating transcription factor 4 | -0.0209996 |
| RPL27A | ribosomal protein L27a | -0.0209922 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0209541 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0208598 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0208303 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0206501 |
| RPL38 | ribosomal protein L38 | -0.0205607 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0204693 |
| PTK2 | protein tyrosine kinase 2 | -0.0204674 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0201097 |
| RPL15 | ribosomal protein L15 | -0.0198026 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0193071 |
| XPO1 | exportin 1 | -0.0191989 |
| RPS15 | ribosomal protein S15 | -0.0191158 |
| RPS13 | ribosomal protein S13 | -0.0190778 |
| SAFB | scaffold attachment factor B | -0.0190522 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0188609 |
