| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | APTO-253 perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the APTO-253_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.187553 |
| PTMA | prothymosin, alpha | 0.0877897 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0458458 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0447106 |
| RCOR1 | REST corepressor 1 | 0.0393843 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0374989 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0371874 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0353489 |
| LAMA4 | laminin, alpha 4 | 0.0343937 |
| EGFR | epidermal growth factor receptor | 0.0320795 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0320412 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0320179 |
| SGMS2 | sphingomyelin synthase 2 | 0.0295629 |
| RPL3 | ribosomal protein L3 | 0.0288081 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0284885 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0273751 |
| SNX9 | sorting nexin 9 | 0.0268392 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0261948 |
| LAMC2 | laminin, gamma 2 | 0.0257824 |
| SEPTIN9 | septin 9 | 0.0253072 |
| VCL | vinculin | 0.024971 |
| NUP50 | nucleoporin 50kDa | 0.0245464 |
| SMAD3 | SMAD family member 3 | 0.024467 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0239141 |
| HMGA2 | high mobility group AT-hook 2 | 0.023116 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0223708 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0222137 |
| FHL2 | four and a half LIM domains 2 | 0.0219355 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0210402 |
| RAD51B | RAD51 paralog B | 0.0208423 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0208064 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0197912 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0195816 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0194901 |
| LAMB3 | laminin, beta 3 | 0.0193853 |
| RPS2 | ribosomal protein S2 | 0.018565 |
| ABR | active BCR-related | 0.018357 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0183092 |
| EFNB2 | ephrin-B2 | 0.0180883 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0180639 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0177363 |
| VMP1 | vacuole membrane protein 1 | 0.0176494 |
| CENPF | centromere protein F, 350/400kDa | 0.0175437 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0174391 |
| ANXA1 | annexin A1 | 0.0172919 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0172502 |
| TXNIP | thioredoxin interacting protein | 0.0168693 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0165324 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0163402 |
| ENO1 | enolase 1, (alpha) | 0.0162311 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0159729 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.015935 |
| GDF15 | growth differentiation factor 15 | 0.0157698 |
| ANLN | anillin, actin binding protein | 0.0155692 |
| FAM120A | family with sequence similarity 120A | 0.0155063 |
| POTEF | POTE ankyrin domain family, member F | 0.0154585 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.01521 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0151516 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0146028 |
| OXSR1 | oxidative stress responsive 1 | 0.0145494 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0144691 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0140143 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0139739 |
| PCBP2 | poly(rC) binding protein 2 | 0.0137798 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0137686 |
| JUN | jun proto-oncogene | 0.0136785 |
| HOMER1 | homer scaffolding protein 1 | 0.0136236 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0136058 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0136056 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0134965 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0133897 |
| DST | dystonin | 0.0133415 |
| CCT2 | chaperonin containing TCP1, subunit 2 (beta) | 0.0132222 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0129889 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0129643 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0129556 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0128279 |
| EZR | ezrin | 0.0127078 |
| CREB5 | cAMP responsive element binding protein 5 | 0.012484 |
| RAB7A | RAB7A, member RAS oncogene family | 0.012426 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0122576 |
| ANXA2 | annexin A2 | 0.0122192 |
| DSPP | dentin sialophosphoprotein | 0.0120928 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0120551 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0119955 |
| CBX3 | chromobox homolog 3 | 0.0119538 |
| DIAPH1 | diaphanous-related formin 1 | 0.0118816 |
| RRM2 | ribonucleotide reductase M2 | 0.0117877 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0117802 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0117525 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0117286 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0114354 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0114195 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0113915 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0113453 |
| FLOT1 | flotillin 1 | 0.0112862 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.011275 |
| FMNL2 | formin-like 2 | 0.011275 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0112486 |
| DCLK1 | doublecortin-like kinase 1 | 0.0111463 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0623411 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0582658 |
| RPS29 | ribosomal protein S29 | -0.0480169 |
| RPLP1 | ribosomal protein, large, P1 | -0.0464312 |
| RPL37A | ribosomal protein L37a | -0.0459759 |
| RPL35A | ribosomal protein L35a | -0.0389687 |
| TMSB10 | thymosin beta 10 | -0.0381154 |
| RPS24 | ribosomal protein S24 | -0.0354683 |
| NDRG1 | N-myc downstream regulated 1 | -0.0341307 |
| RPLP2 | ribosomal protein, large, P2 | -0.0331586 |
| RBM25 | RNA binding motif protein 25 | -0.0322163 |
| RPS12 | ribosomal protein S12 | -0.0318919 |
| RPS3 | ribosomal protein S3 | -0.0307428 |
| RPS6 | ribosomal protein S6 | -0.0299733 |
| FAT1 | FAT atypical cadherin 1 | -0.0283619 |
| RPL26 | ribosomal protein L26 | -0.0275 |
| RNF43 | ring finger protein 43 | -0.0268632 |
| RPS13 | ribosomal protein S13 | -0.0263964 |
| RPL9 | ribosomal protein L9 | -0.0257983 |
| MT2A | metallothionein 2A | -0.0250843 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0249644 |
| RPL11 | ribosomal protein L11 | -0.0245512 |
| RPS25 | ribosomal protein S25 | -0.0204197 |
| GOLGA4 | golgin A4 | -0.0198064 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0191808 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0190717 |
| RPL36 | ribosomal protein L36 | -0.0188402 |
| RPS19 | ribosomal protein S19 | -0.0185941 |
| RPL34 | ribosomal protein L34 | -0.018426 |
| RPL12 | ribosomal protein L12 | -0.0183988 |
| RPS27A | ribosomal protein S27a | -0.0178759 |
| RPL38 | ribosomal protein L38 | -0.0177664 |
| HLA-B | major histocompatibility complex, class I, B | -0.01738 |
| RPS21 | ribosomal protein S21 | -0.0169061 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0168911 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0167591 |
| EVA1C | eva-1 homolog C (C. elegans) | -0.0167511 |
| RPL27A | ribosomal protein L27a | -0.0167338 |
| RUNX2 | runt-related transcription factor 2 | -0.0164789 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0163456 |
| OGA | O-GlcNAcase | -0.0159834 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0158024 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0154481 |
| RPS27 | ribosomal protein S27 | -0.0153788 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0153158 |
| RPS15 | ribosomal protein S15 | -0.015289 |
| SCFD1 | sec1 family domain containing 1 | -0.0148783 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0148362 |
| SERINC5 | serine incorporator 5 | -0.0147788 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0147676 |
| RPL13A | ribosomal protein L13a | -0.0147593 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0143818 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0142752 |
| GNAS | GNAS complex locus | -0.0142439 |
| TPM4 | tropomyosin 4 | -0.0142394 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0141351 |
| USP34 | ubiquitin specific peptidase 34 | -0.0140478 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0137585 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0136304 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0134092 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0132728 |
| YLPM1 | YLP motif containing 1 | -0.013066 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.012807 |
| ERBIN | erbb2 interacting protein | -0.0127373 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0127252 |
| RPS16 | ribosomal protein S16 | -0.0126261 |
| PHIP | pleckstrin homology domain interacting protein | -0.0125895 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0125711 |
| ZNF638 | zinc finger protein 638 | -0.0125003 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0124996 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0124393 |
| RPL7A | ribosomal protein L7a | -0.0124139 |
| RPL5 | ribosomal protein L5 | -0.0124051 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0122649 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0121059 |
| PFKP | phosphofructokinase, platelet | -0.0120872 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0120183 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0119991 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.011843 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0116566 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0116394 |
| RPL37 | ribosomal protein L37 | -0.0115349 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0115087 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0114386 |
| RPL28 | ribosomal protein L28 | -0.0114134 |
| DENND1A | DENN/MADD domain containing 1A | -0.011377 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0113585 |
| PHF14 | PHD finger protein 14 | -0.0113576 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0113532 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0112886 |
| RPL31 | ribosomal protein L31 | -0.0112816 |
| RPS23 | ribosomal protein S23 | -0.0112513 |
| ARFGEF3 | ARFGEF family member 3 | -0.0111879 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0111734 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0111632 |
| HDAC8 | histone deacetylase 8 | -0.0111024 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | -0.0110009 |
| THOC1 | THO complex 1 | -0.0109836 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0109559 |
| FTL | ferritin, light polypeptide | -0.0109083 |
