| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | APTO-253 perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the APTO-253_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.176073 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.155698 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.118618 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.10474 |
| SYT1 | synaptotagmin I | 0.095908 |
| TNS3 | tensin 3 | 0.0849711 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.080979 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0761897 |
| WWOX | WW domain containing oxidoreductase | 0.0668322 |
| RPS6 | ribosomal protein S6 | 0.0619042 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0612321 |
| POTEF | POTE ankyrin domain family, member F | 0.053151 |
| ENO1 | enolase 1, (alpha) | 0.0508462 |
| RPS19 | ribosomal protein S19 | 0.0501109 |
| RPS12 | ribosomal protein S12 | 0.0479633 |
| PCBP2 | poly(rC) binding protein 2 | 0.0475963 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0473946 |
| CENPF | centromere protein F, 350/400kDa | 0.0461263 |
| RPS8 | ribosomal protein S8 | 0.0442861 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0439439 |
| RPLP1 | ribosomal protein, large, P1 | 0.0436939 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0436546 |
| EGR1 | early growth response 1 | 0.0432795 |
| MT2A | metallothionein 2A | 0.0428386 |
| RPS23 | ribosomal protein S23 | 0.0425974 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0419306 |
| RPL3 | ribosomal protein L3 | 0.0374398 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0368076 |
| RPL7 | ribosomal protein L7 | 0.0356184 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0352935 |
| RPL5 | ribosomal protein L5 | 0.0352124 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0348911 |
| YAP1 | Yes-associated protein 1 | 0.0344851 |
| RPLP2 | ribosomal protein, large, P2 | 0.0338243 |
| RPS2 | ribosomal protein S2 | 0.0334933 |
| DSPP | dentin sialophosphoprotein | 0.0334868 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0323148 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0319862 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0317287 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0309804 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0307939 |
| RPL21 | ribosomal protein L21 | 0.0304815 |
| TUBA1B | tubulin, alpha 1b | 0.0303782 |
| RAD51B | RAD51 paralog B | 0.0296903 |
| RPS17 | ribosomal protein S17 | 0.0296735 |
| YBX1 | Y box binding protein 1 | 0.0293404 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0290812 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0289777 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0287973 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0278566 |
| PCM1 | pericentriolar material 1 | 0.0277515 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0274853 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0271192 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0268259 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0263887 |
| CBX3 | chromobox homolog 3 | 0.0263118 |
| RPL32 | ribosomal protein L32 | 0.0257575 |
| FOXP1 | forkhead box P1 | 0.0255839 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.025242 |
| RPL37 | ribosomal protein L37 | 0.0251489 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0250988 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0250012 |
| MSN | moesin | 0.0249434 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0249174 |
| CDK6 | cyclin-dependent kinase 6 | 0.0249072 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0248648 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0245758 |
| MKI67 | marker of proliferation Ki-67 | 0.0243335 |
| RPS4X | ribosomal protein S4, X-linked | 0.0242423 |
| BMP5 | bone morphogenetic protein 5 | 0.0231204 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | 0.0229062 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0228389 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0228346 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.022481 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0224398 |
| GSPT1 | G1 to S phase transition 1 | 0.0223241 |
| RPL35A | ribosomal protein L35a | 0.0222168 |
| STK38L | serine/threonine kinase 38 like | 0.0221604 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0221234 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0217584 |
| SET | SET nuclear proto-oncogene | 0.0216084 |
| RACK1 | receptor for activated C kinase 1 | 0.0213563 |
| EXOC4 | exocyst complex component 4 | 0.0212981 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0210951 |
| ZNRF3 | zinc and ring finger 3 | 0.0208572 |
| RPL9 | ribosomal protein L9 | 0.0207267 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0206716 |
| RPL35 | ribosomal protein L35 | 0.0205655 |
| PNN | pinin, desmosome associated protein | 0.0205201 |
| MCC | mutated in colorectal cancers | 0.0202957 |
| BPTF | bromodomain PHD finger transcription factor | 0.0201943 |
| RPS27 | ribosomal protein S27 | 0.0198324 |
| NOTUM | notum pectinacetylesterase homolog (Drosophila) | 0.0197577 |
| TXNIP | thioredoxin interacting protein | 0.0196421 |
| SMAD3 | SMAD family member 3 | 0.0195352 |
| RPS29 | ribosomal protein S29 | 0.0194634 |
| RPL19 | ribosomal protein L19 | 0.0194053 |
| RPS20 | ribosomal protein S20 | 0.0192038 |
| LDHB | lactate dehydrogenase B | 0.0191534 |
| TMSB10 | thymosin beta 10 | 0.0191527 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.154999 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.122064 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0959698 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0785117 |
| AHNAK | AHNAK nucleoprotein | -0.0774989 |
| ANXA2 | annexin A2 | -0.0756742 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0702711 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0649251 |
| KRT18 | keratin 18, type I | -0.0643818 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0633852 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0623702 |
| GOLGA4 | golgin A4 | -0.0602534 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0591002 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0584696 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0560351 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0530243 |
| FLNB | filamin B, beta | -0.0528586 |
| ITGA6 | integrin, alpha 6 | -0.0526827 |
| CDH13 | cadherin 13 | -0.0519018 |
| ASPH | aspartate beta-hydroxylase | -0.0505503 |
| RBM39 | RNA binding motif protein 39 | -0.0490059 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0486245 |
| CANX | calnexin | -0.0483865 |
| NAV2 | neuron navigator 2 | -0.0476517 |
| COG5 | component of oligomeric golgi complex 5 | -0.0461644 |
| OGA | O-GlcNAcase | -0.0453911 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.044597 |
| ANLN | anillin, actin binding protein | -0.0440765 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0433725 |
| MORF4L2 | mortality factor 4 like 2 | -0.0432635 |
| H1-0 | H1.0 linker histone | -0.0430462 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.042009 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.041373 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.039197 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0387537 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0385283 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.038284 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0380973 |
| KRT8 | keratin 8, type II | -0.0371315 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0370713 |
| GLG1 | golgi glycoprotein 1 | -0.0368122 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0363878 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0360748 |
| SDC4 | syndecan 4 | -0.035682 |
| FRMD5 | FERM domain containing 5 | -0.0350862 |
| USP34 | ubiquitin specific peptidase 34 | -0.0348218 |
| INTS6 | integrator complex subunit 6 | -0.0347361 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0344195 |
| NF1 | neurofibromin 1 | -0.0343832 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0337702 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0336545 |
| S100A10 | S100 calcium binding protein A10 | -0.0334948 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0333219 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0332567 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0331953 |
| RPS24 | ribosomal protein S24 | -0.033122 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0318202 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0317651 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0315562 |
| DOCK9 | dedicator of cytokinesis 9 | -0.0312219 |
| TPM4 | tropomyosin 4 | -0.0312191 |
| ZNF292 | zinc finger protein 292 | -0.0311585 |
| CEP95 | centrosomal protein 95kDa | -0.0311105 |
| NDRG1 | N-myc downstream regulated 1 | -0.0307883 |
| SBF2 | SET binding factor 2 | -0.0303738 |
| TMEM41B | transmembrane protein 41B | -0.0303546 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0302523 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0301564 |
| RASA3 | RAS p21 protein activator 3 | -0.0299945 |
| IER3 | immediate early response 3 | -0.0298941 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0298401 |
| AFDN | afadin, adherens junction formation factor | -0.0295034 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0294548 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0293648 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0292765 |
| KRT19 | keratin 19, type I | -0.0291613 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0287858 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0284592 |
| FNIP1 | folliculin interacting protein 1 | -0.0281493 |
| RASA2 | RAS p21 protein activator 2 | -0.0278611 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0277826 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0273289 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0272651 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0270172 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.026886 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0262874 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0262614 |
| NTSR1 | neurotensin receptor 1 (high affinity) | -0.026179 |
| MYOF | myoferlin | -0.0261697 |
| FBXO11 | F-box protein 11 | -0.0259843 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0259429 |
| PLEC | plectin | -0.0258036 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0254147 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0253904 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0251149 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0250862 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | -0.0248801 |
| TMSB4X | thymosin beta 4, X-linked | -0.0248309 |
| HMGA1 | high mobility group AT-hook 1 | -0.0245039 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0243992 |
