AQP1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description aquaporin 1 (Colton blood group)|Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This gene encodes an aquaporin which functions as a molecular water channel protein. It is a homotetramer with 6 bilayer spanning domains and N-glycosylation sites. The protein physically resembles channel proteins and is abundant in erythrocytes and renal tubes. The gene encoding this aquaporin is a possible candidate for disorders involving imbalance in ocular fluid movement. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010] (NCBI Entrez Gene Database, 358)
External Link https://ncbi.nlm.nih.gov/gene/358
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Genes

499 genes differentially expressed following the AQP1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
MEF2C myocyte enhancer factor 2C 0.0291114
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 0.0143566
BGN biglycan 0.0138225
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.0135196
TMSB15A thymosin beta 15a 0.0128869
RFC5 replication factor C (activator 1) 5, 36.5kDa 0.0125444
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.012359
CDCA4 cell division cycle associated 4 0.011914
AMIGO2 adhesion molecule with Ig-like domain 2 0.011644
FRZB frizzled-related protein 0.0114188
ADGRF5 adhesion G protein-coupled receptor F5 0.0113919
ADIRF adipogenesis regulatory factor 0.0113811
CCN2 cellular communication network factor 2 0.0112603
OLFM1 olfactomedin 1 0.0111272
CAV1 caveolin 1, caveolae protein, 22kDa 0.0109023
SIK1 salt-inducible kinase 1 0.0107529
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.0107065
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.0105602
SLC38A1 solute carrier family 38, member 1 0.0105341
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 0.0104377
LIMCH1 LIM and calponin homology domains 1 0.0103257
FBP1 fructose-1,6-bisphosphatase 1 0.0102246
ARMCX2 armadillo repeat containing, X-linked 2 0.0101626
HHEX hematopoietically expressed homeobox 0.00990618
TBX3 T-box 3 0.00983167
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.00977837
NDNF neuron-derived neurotrophic factor 0.0097601
ENC1 ectodermal-neural cortex 1 (with BTB domain) 0.00963585
TSPAN13 tetraspanin 13 0.00962805
MMP2 matrix metallopeptidase 2 0.00950406
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.00945257
ADCY9 adenylate cyclase 9 0.00944568
KRT19 keratin 19, type I 0.00943217
VWF von Willebrand factor 0.00928411
IRS1 insulin receptor substrate 1 0.00921809
ZNF532 zinc finger protein 532 0.00921062
LMO3 LIM domain only 3 (rhombotin-like 2) 0.00912454
ELN elastin 0.00910577
ARHGAP29 Rho GTPase activating protein 29 0.00908639
PBX1 pre-B-cell leukemia homeobox 1 0.00907021
HSPB8 heat shock 22kDa protein 8 0.00904767
TENT4A terminal nucleotidyltransferase 4A 0.00892852
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.00887593
ARG2 arginase 2 0.0087931
ANOS1 anosmin 1 0.00873051
CXCL9 chemokine (C-X-C motif) ligand 9 0.00867514
CYRIA CYFIP related Rac1 interactor A 0.00865768
EFHD1 EF-hand domain family, member D1 0.00865048
IGFBP4 insulin-like growth factor binding protein 4 0.00859562
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.00858918
INSR insulin receptor 0.00858558
PCDH17 protocadherin 17 0.00856539
RAMP3 receptor (G protein-coupled) activity modifying protein 3 0.00852807
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 0.00852646
HK2 hexokinase 2 0.00847585
CEP55 centrosomal protein 55kDa 0.00846204
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.00838616
AMOTL2 angiomotin like 2 0.00838566
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 0.00835023
PDE2A phosphodiesterase 2A, cGMP-stimulated 0.00828946
KCNK3 potassium channel, two pore domain subfamily K, member 3 0.00823279
TTN titin 0.00818377
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.00816829
CTSZ cathepsin Z 0.00801276
TGM2 transglutaminase 2 0.00800276
RHOBTB3 Rho-related BTB domain containing 3 0.00795126
KANK2 KN motif and ankyrin repeat domains 2 0.00794956
KAZN kazrin, periplakin interacting protein 0.00790127
CDC7 cell division cycle 7 0.00787934
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 0.00784516
C1QB complement component 1, q subcomponent, B chain 0.00784443
KIF11 kinesin family member 11 0.00779047
LAMP5 lysosomal-associated membrane protein family, member 5 0.00775214
C1QA complement component 1, q subcomponent, A chain 0.00770812
CAV2 caveolin 2 0.00766201
KIF18B kinesin family member 18B 0.00765934
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.00765689
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.00763596
ENO3 enolase 3 (beta, muscle) 0.00762954
PBX3 pre-B-cell leukemia homeobox 3 0.00762399
ACTA1 actin, alpha 1, skeletal muscle 0.00756199
PRELP proline/arginine-rich end leucine-rich repeat protein 0.00755976
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.0075511
RXRA retinoid X receptor, alpha 0.00754379
TNS3 tensin 3 0.00750512
TNS1 tensin 1 0.00750098
NELL2 NEL-like 2 (chicken) 0.00750039
EZR ezrin 0.0074506
CBS cystathionine-beta-synthase 0.00738473
FEN1 flap structure-specific endonuclease 1 0.00730702
RBL2 retinoblastoma-like 2 0.00729167
BMP2 bone morphogenetic protein 2 0.0072333
RTN2 reticulon 2 0.00723133
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.00722877
HMGB1 high mobility group box 1 0.00718529
CREB3L2 cAMP responsive element binding protein 3-like 2 0.00718153
BPIFA1 BPI fold containing family A, member 1 0.00717169
CKM creatine kinase, muscle 0.00714128
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.00711208
TNNT1 troponin T type 1 (skeletal, slow) 0.00709758
MYL1 myosin, light chain 1, alkali; skeletal, fast 0.00709121
DLK1 delta-like 1 homolog (Drosophila) 0.00708081
NDC80 NDC80 kinetochore complex component 0.00706113
HAUS3 HAUS augmin-like complex, subunit 3 0.0070457
DCAF10 DDB1 and CUL4 associated factor 10 0.0070394
RBM6 RNA binding motif protein 6 0.00702772
FCN3 ficolin (collagen/fibrinogen domain containing) 3 0.00699033
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 0.00698881
ACTC1 actin, alpha, cardiac muscle 1 0.00697438
SFRP1 secreted frizzled-related protein 1 0.00696896
NEFH neurofilament, heavy polypeptide 0.00696749
CENPE centromere protein E, 312kDa 0.00696051
FOXM1 forkhead box M1 0.00695518
VEGFA vascular endothelial growth factor A 0.00693541
NKX3-1 NK3 homeobox 1 0.00692001
STAB1 stabilin 1 0.00691423
FBXO21 F-box protein 21 0.00689933
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 0.00688968
NBEA neurobeachin 0.00688701
DUSP3 dual specificity phosphatase 3 0.00688394
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.00688023
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.00687124
PLD3 phospholipase D family, member 3 0.00684237
RAB8A RAB8A, member RAS oncogene family 0.00684153
ERBB4 erb-b2 receptor tyrosine kinase 4 0.00683369
ACD adrenocortical dysplasia homolog (mouse) 0.0068304
FXYD6 FXYD domain containing ion transport regulator 6 0.00682213
PDE4D phosphodiesterase 4D, cAMP-specific 0.0068033
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.00680324
CALCRL calcitonin receptor-like 0.00675656
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase 0.00670585
NCAPD3 non-SMC condensin II complex, subunit D3 0.00670437
LTBP2 latent transforming growth factor beta binding protein 2 0.00668778
MBNL1 muscleblind-like splicing regulator 1 0.00667631
PLXNA1 plexin A1 0.00661671
CDK13 cyclin-dependent kinase 13 0.00659626
JCHAIN joining chain of multimeric IgA and IgM 0.00659415
RGS13 regulator of G-protein signaling 13 0.00656904
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.00656483
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.00655822
GPX3 glutathione peroxidase 3 0.00653322
IGF1 insulin-like growth factor 1 (somatomedin C) 0.00651892
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.00651469
OLFML2A olfactomedin-like 2A 0.00649545
FLT1 fms-related tyrosine kinase 1 0.00648972
HMGB3 high mobility group box 3 0.00648924
SH3BGRL SH3 domain binding glutamate-rich protein like 0.0064866
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase 0.00646937
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.00646727
HELLS helicase, lymphoid-specific 0.00646102
TYROBP TYRO protein tyrosine kinase binding protein 0.00644471
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.00643522
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00642893
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00641833
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.00640509
MYH11 myosin, heavy chain 11, smooth muscle 0.00639804
NXN nucleoredoxin 0.00639513
LDOC1 leucine zipper, down-regulated in cancer 1 0.00639472
LDB2 LIM domain binding 2 0.00637727
WWC2 WW and C2 domain containing 2 0.00637092
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.00636596
CHRDL1 chordin-like 1 0.00636396
CES1 carboxylesterase 1 0.00636335
SLCO3A1 solute carrier organic anion transporter family, member 3A1 0.00635817
GUCY2C guanylate cyclase 2C 0.00633712
TNNI2 troponin I type 2 (skeletal, fast) 0.00633336
XIC X chromosome inactivation center 0.00633084
CCDC92 coiled-coil domain containing 92 0.00632631
GLS2 glutaminase 2 (liver, mitochondrial) 0.00631554
SUSD4 sushi domain containing 4 0.00630589
SLCO4A1 solute carrier organic anion transporter family, member 4A1 0.00629656
A2M alpha-2-macroglobulin 0.00628051
ZBTB38 zinc finger and BTB domain containing 38 0.0062606
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.00624339
CD40 CD40 molecule, TNF receptor superfamily member 5 0.00623638
BANK1 B-cell scaffold protein with ankyrin repeats 1 0.00622176
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 0.00620551
CCNF cyclin F 0.00620218
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 0.00619668
CTNND1 catenin (cadherin-associated protein), delta 1 0.00618885
ZNF217 zinc finger protein 217 0.00618554
CIT citron rho-interacting serine/threonine kinase 0.00617109
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 0.00612443
SFTPD surfactant protein D 0.00612068
ADCY1 adenylate cyclase 1 (brain) 0.00611635
SPIN1 spindlin 1 0.0061141
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.00610677
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.00610638
ZCCHC2 zinc finger, CCHC domain containing 2 0.006101
KIF20A kinesin family member 20A 0.00610062
CHP1 calcineurin-like EF-hand protein 1 0.00608611
CPE carboxypeptidase E 0.00607135
LYPLA1 lysophospholipase I 0.00606674
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 0.00606212
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 0.00606044
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.00605419
TGFB1 transforming growth factor, beta 1 0.00603145
TMEM45A transmembrane protein 45A 0.00602379
EHD3 EH-domain containing 3 0.0060235
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 0.00602043
THBD thrombomodulin 0.00600664
HYOU1 hypoxia up-regulated 1 0.00599767
FOXN3 forkhead box N3 0.00598595
PCSK6 proprotein convertase subtilisin/kexin type 6 0.00597356
TCF4 transcription factor 4 0.00596246
VIPR1 vasoactive intestinal peptide receptor 1 0.00595848
PGRMC2 progesterone receptor membrane component 2 0.00595537
ABHD6 abhydrolase domain containing 6 0.00593481
RASIP1 Ras interacting protein 1 0.00593097
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 0.00592946
SUB1 SUB1 homolog (S. cerevisiae) 0.00592813
P3H2 prolyl 3-hydroxylase 2 0.00592586
MYBPC1 myosin binding protein C, slow type 0.00591703
GSN gelsolin 0.0059159
TSEN2 TSEN2 tRNA splicing endonuclease subunit 0.00590388
MED13L mediator complex subunit 13-like 0.00588973
ORC6 origin recognition complex, subunit 6 0.00588963
DUSP7 dual specificity phosphatase 7 0.00587884
KRT17 keratin 17, type I 0.00587748
IRAK1 interleukin-1 receptor-associated kinase 1 0.00587001
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.00586935
ESYT1 extended synaptotagmin-like protein 1 0.00586445
PRKCI protein kinase C, iota 0.00586386
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) 0.00585813
PDLIM5 PDZ and LIM domain 5 0.00584657
LMNB2 lamin B2 0.00583876
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 0.00583713
SDC4 syndecan 4 0.00583608
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.00583524
NLRP2 NLR family, pyrin domain containing 2 0.00583185
TNNC1 troponin C type 1 (slow) 0.00583043
HIC2 hypermethylated in cancer 2 0.00582724
CISH cytokine inducible SH2-containing protein 0.00582602
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 0.00582311
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 0.00581572
JADE1 jade family PHD finger 1 0.00580795
RDX radixin 0.00580453
GOLGA8A golgin A8 family, member A 0.00579914
CUX2 cut-like homeobox 2 0.00579507
PMM2 phosphomannomutase 2 0.00579236
KRT18 keratin 18, type I 0.00577492
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 0.00576545
CLSTN2 calsyntenin 2 0.00575815
ZWINT ZW10 interacting kinetochore protein 0.00575788
RB1 retinoblastoma 1 0.00575702
CCND2 cyclin D2 0.00575027
TOP2A topoisomerase (DNA) II alpha 170kDa 0.00574969
IFT81 intraflagellar transport 81 0.00574838
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.00574825
FAM189A2 family with sequence similarity 189, member A2 0.00574783

decreased expression

Symbol Name Standardized Value
TUBB2A tubulin, beta 2A class IIa -0.0202298
MME membrane metallo-endopeptidase -0.0151641
LTF lactotransferrin -0.0149227
S100A7 S100 calcium binding protein A7 -0.0147387
IFI27 interferon, alpha-inducible protein 27 -0.0147297
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -0.0145379
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.0144047
S100A9 S100 calcium binding protein A9 -0.014065
PRR7 proline rich 7 (synaptic) -0.0136701
ZIC1 Zic family member 1 -0.013496
PITX3 paired-like homeodomain 3 -0.013012
TUBB2B tubulin, beta 2B class IIb -0.0128232
LCN2 lipocalin 2 -0.0127543
REG3A regenerating islet-derived 3 alpha -0.0127024
SCGB2A1 secretoglobin, family 2A, member 1 -0.0125002
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -0.0122868
ARPP19 cAMP-regulated phosphoprotein, 19kDa -0.0121257
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) -0.0119612
SEPP1 selenoprotein P, plasma, 1 -0.0117689
PI3 peptidase inhibitor 3, skin-derived -0.0116136
TSPAN8 tetraspanin 8 -0.0116007
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.0115879
GPM6B glycoprotein M6B -0.0114833
ATF3 activating transcription factor 3 -0.0112542
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -0.0112138
CA12 carbonic anhydrase XII -0.010954
ECI2 enoyl-CoA delta isomerase 2 -0.0109399
KIAA0226L KIAA0226-like -0.0108476
DSP desmoplakin -0.0108091
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.0107612
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -0.0107395
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.0107067
MEN1 multiple endocrine neoplasia I -0.0106366
PERP PERP, TP53 apoptosis effector -0.0104623
REG1A regenerating islet-derived 1 alpha -0.010432
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -0.010419
SRPX sushi-repeat containing protein, X-linked -0.0103637
CSTA cystatin A (stefin A) -0.0103472
TM4SF1 transmembrane 4 L six family member 1 -0.0102967
CEMIP cell migration inducing protein, hyaluronan binding -0.0102925
F12 coagulation factor XII (Hageman factor) -0.0102921
IFITM3 interferon induced transmembrane protein 3 -0.0102839
FCGBP Fc fragment of IgG binding protein -0.0102074
BCL2A1 BCL2-related protein A1 -0.0101939
MVP major vault protein -0.0101803
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -0.0100922
LGALS4 lectin, galactoside-binding, soluble, 4 -0.009988
GNAS GNAS complex locus -0.00995178
RPS5 ribosomal protein S5 -0.00993327
HBD hemoglobin, delta -0.00988202
MAL mal, T-cell differentiation protein -0.00987517
S100B S100 calcium binding protein B -0.00980097
PDZK1IP1 PDZK1 interacting protein 1 -0.00975098
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00971731
NQO1 NAD(P)H dehydrogenase, quinone 1 -0.0096925
ADD3 adducin 3 (gamma) -0.00965922
SST somatostatin -0.00960755
FAM171A1 family with sequence similarity 171, member A1 -0.0095627
SPON1 spondin 1, extracellular matrix protein -0.00952637
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.00949114
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00944458
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) -0.00944129
PHLDA2 pleckstrin homology-like domain, family A, member 2 -0.00942959
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -0.009301
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.00926847
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -0.0092583
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.0092478
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.0091467
S100A10 S100 calcium binding protein A10 -0.00913389
MREG melanoregulin -0.00891424
TAC1 tachykinin, precursor 1 -0.00889275
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 -0.00878353
CLDN10 claudin 10 -0.00874505
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.00873935
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -0.00870227
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -0.00868826
TYRP1 tyrosinase-related protein 1 -0.00868801
SAT1 spermidine/spermine N1-acetyltransferase 1 -0.00867221
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.0086246
CD58 CD58 molecule -0.00858598
IFI44L interferon-induced protein 44-like -0.00853408
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -0.00849142
TP53I3 tumor protein p53 inducible protein 3 -0.00841259
COCH cochlin -0.00838051
ADA adenosine deaminase -0.00837818
CXCL5 chemokine (C-X-C motif) ligand 5 -0.00835376
KRT6B keratin 6B, type II -0.00831448
CFB complement factor B -0.00830099
RCAN1 regulator of calcineurin 1 -0.00822809
HSPB1 heat shock 27kDa protein 1 -0.00820436
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00812873
B2M beta-2-microglobulin -0.00812532
ALDOB aldolase B, fructose-bisphosphate -0.00810654
CFI complement factor I -0.00810528
SELL selectin L -0.00808588
HIGD2A HIG1 hypoxia inducible domain family, member 2A -0.00808086
RPL36 ribosomal protein L36 -0.00806931
GMDS GDP-mannose 4,6-dehydratase -0.00804337
CYFIP2 cytoplasmic FMR1 interacting protein 2 -0.00804261
RGS10 regulator of G-protein signaling 10 -0.00803721
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -0.00799756
ISG20 interferon stimulated exonuclease gene 20kDa -0.00796125
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00795662
SNCA synuclein, alpha (non A4 component of amyloid precursor) -0.007922
CCL20 chemokine (C-C motif) ligand 20 -0.00785
C1QTNF3 C1q and tumor necrosis factor related protein 3 -0.00782709
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 -0.00782503
POLR1D polymerase (RNA) I polypeptide D, 16kDa -0.00781573
USP18 ubiquitin specific peptidase 18 -0.00781566
DCN decorin -0.00778897
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 -0.00776026
HSPA2 heat shock 70kDa protein 2 -0.00774752
ANXA11 annexin A11 -0.00773457
COX4I1 cytochrome c oxidase subunit IV isoform 1 -0.00772956
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.00770198
CD59 CD59 molecule, complement regulatory protein -0.00770108
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -0.00769771
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00768802
BATF3 basic leucine zipper transcription factor, ATF-like 3 -0.00768679
PRUNE2 prune homolog 2 (Drosophila) -0.00767361
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -0.00765707
ADAM28 ADAM metallopeptidase domain 28 -0.00765197
HLA-B major histocompatibility complex, class I, B -0.00762897
GYPC glycophorin C (Gerbich blood group) -0.00761924
TIMP4 TIMP metallopeptidase inhibitor 4 -0.00758897
EMX2 empty spiracles homeobox 2 -0.00757277
SPRR1B small proline-rich protein 1B -0.00757272
FAM117A family with sequence similarity 117, member A -0.00754722
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -0.00752165
KRT6A keratin 6A, type II -0.00752101
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 -0.00750535
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -0.00748258
KRT5 keratin 5, type II -0.00744932
CNR1 cannabinoid receptor 1 (brain) -0.00744501
MGAM maltase-glucoamylase -0.00742314
HCP5 HLA complex P5 (non-protein coding) -0.00737828
F2RL1 coagulation factor II (thrombin) receptor-like 1 -0.00734872
ASRGL1 asparaginase like 1 -0.00734614
AOC1 amine oxidase, copper containing 1 -0.00731419
CLTB clathrin, light chain B -0.00730778
TFF1 trefoil factor 1 -0.00730693
PMP2 peripheral myelin protein 2 -0.00730256
MSX1 msh homeobox 1 -0.00729068
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00728977
GDF15 growth differentiation factor 15 -0.00726095
OLFM4 olfactomedin 4 -0.00720979
C5AR1 complement component 5a receptor 1 -0.0071765
PRKCA protein kinase C, alpha -0.00717104
ACSL5 acyl-CoA synthetase long-chain family member 5 -0.00711253
RPS14P3 ribosomal protein S14 pseudogene 3 -0.00710974
IFIH1 interferon induced with helicase C domain 1 -0.00708639
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor -0.00708525
CPVL carboxypeptidase, vitellogenic-like -0.00703576
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 -0.00703379
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -0.007029
EYA2 EYA transcriptional coactivator and phosphatase 2 -0.00701505
IFI44 interferon-induced protein 44 -0.0070119
PPA1 pyrophosphatase (inorganic) 1 -0.00700402
IFI35 interferon-induced protein 35 -0.00700401
DHDDS dehydrodolichyl diphosphate synthase -0.00697539
CXCL3 chemokine (C-X-C motif) ligand 3 -0.00694294
MFAP5 microfibrillar associated protein 5 -0.00692718
STEAP1 six transmembrane epithelial antigen of the prostate 1 -0.00692324
CD52 CD52 molecule -0.00692315
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 -0.0069163
PRAME preferentially expressed antigen in melanoma -0.00691576
LY6D lymphocyte antigen 6 complex, locus D -0.00690762
GCA grancalcin, EF-hand calcium binding protein -0.00690595
BAMBI BMP and activin membrane-bound inhibitor -0.00689332
ATP5PD ATP synthase peripheral stalk subunit d -0.00685906
IFI6 interferon, alpha-inducible protein 6 -0.00684638
S100A14 S100 calcium binding protein A14 -0.00683382
CCR7 chemokine (C-C motif) receptor 7 -0.00682447
IFITM2 interferon induced transmembrane protein 2 -0.00680489
MEOX2 mesenchyme homeobox 2 -0.00678263
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) -0.00676904
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -0.00676036
LPIN1 lipin 1 -0.00675185
SLC22A18 solute carrier family 22, member 18 -0.00673474
KCTD12 potassium channel tetramerization domain containing 12 -0.00671253
MIA melanoma inhibitory activity -0.00669571
WASHC4 WASH complex subunit 4 -0.00666416
NEBL nebulette -0.00666365
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) -0.00664621
LRRC17 leucine rich repeat containing 17 -0.00664601
ARG1 arginase 1 -0.00662053
COG2 component of oligomeric golgi complex 2 -0.00661104
DDIT4 DNA-damage-inducible transcript 4 -0.00659795
OGDHL oxoglutarate dehydrogenase-like -0.00656557
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) -0.00655963
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) -0.00655579
RPL14 ribosomal protein L14 -0.00650089
HSPA1A heat shock 70kDa protein 1A -0.00649999
BAALC brain and acute leukemia, cytoplasmic -0.00647211
AREG amphiregulin -0.00642232
EHF ets homologous factor -0.00641136
CRYL1 crystallin, lambda 1 -0.00640947
AKR1C3 aldo-keto reductase family 1, member C3 -0.00640896
CASP7 caspase 7, apoptosis-related cysteine peptidase -0.00638529
CCNG1 cyclin G1 -0.00637216
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.00636223
LYRM4 LYR motif containing 4 -0.00635185
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.00634263
FGF1 fibroblast growth factor 1 (acidic) -0.00633978
CXCL2 chemokine (C-X-C motif) ligand 2 -0.00633098
KYNU kynureninase -0.00630966
WIPI1 WD repeat domain, phosphoinositide interacting 1 -0.00630498
BTF3P11 basic transcription factor 3 pseudogene 11 -0.00629827
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.00627926
HIST1H2AC histone cluster 1, H2ac -0.00627854
A1CF APOBEC1 complementation factor -0.00627561
SLA Src-like-adaptor -0.00626356
COX5B cytochrome c oxidase subunit Vb -0.00624679
TMED9 transmembrane emp24 protein transport domain containing 9 -0.00624042
HMOX1 heme oxygenase 1 -0.00623638
BAG3 BCL2-associated athanogene 3 -0.00622939
DUSP2 dual specificity phosphatase 2 -0.00621992
SOX9 SRY (sex determining region Y)-box 9 -0.00621767
ALOX5AP arachidonate 5-lipoxygenase-activating protein -0.00621388
GOLT1B golgi transport 1B -0.00618864
FKBP11 FK506 binding protein 11, 19 kDa -0.00617979
GCH1 GTP cyclohydrolase 1 -0.0061558
BTN3A3 butyrophilin, subfamily 3, member A3 -0.00615551
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -0.00615091
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide -0.00614939
COL9A3 collagen, type IX, alpha 3 -0.00614551
BPHL biphenyl hydrolase-like (serine hydrolase) -0.00614475
ACTB actin, beta -0.00614173
GLRX glutaredoxin (thioltransferase) -0.00614085
ACE2 angiotensin I converting enzyme 2 -0.00613593
MYO1C myosin IC -0.00612771
TCL1A T-cell leukemia/lymphoma 1A -0.00610338
IQCG IQ motif containing G -0.0060957
S100A8 S100 calcium binding protein A8 -0.00607576
OSBPL9 oxysterol binding protein-like 9 -0.00607512
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 -0.00605736
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 -0.0060524
BIN1 bridging integrator 1 -0.00604381
MYB v-myb avian myeloblastosis viral oncogene homolog -0.00602492
CLNS1A chloride channel, nucleotide-sensitive, 1A -0.00601994
ADM adrenomedullin -0.00599981
ITGB4 integrin, beta 4 -0.00599506
SPRR2B small proline-rich protein 2B -0.00599332
KLK7 kallikrein-related peptidase 7 -0.00599306
PLBD1 phospholipase B domain containing 1 -0.00596121
GPR137B G protein-coupled receptor 137B -0.00594902
HOXB2 homeobox B2 -0.00594888
TOM1L1 target of myb1 (chicken)-like 1 -0.00593999
RHOC ras homolog family member C -0.00592608