AR-A014418-7097 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the AR-A014418-7097 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANKRD12 ankyrin repeat domain 12
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ASPH aspartate beta-hydroxylase
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CASKIN2 CASK interacting protein 2
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLCC1 chloride channel CLIC-like 1
CLTB clathrin, light chain B
COX15 cytochrome c oxidase assembly homolog 15 (yeast)
CXCL8 chemokine (C-X-C motif) ligand 8
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DST dystonin
EGFR epidermal growth factor receptor
EIF4E eukaryotic translation initiation factor 4E
ELF1 E74-like factor 1 (ets domain transcription factor)
ETAA1 Ewing tumor-associated antigen 1
FCHSD2 FCH and double SH3 domains 2
FGFR1OP FGFR1 oncogene partner
FOSL2 FOS-like antigen 2
FUBP1 far upstream element (FUSE) binding protein 1
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GCFC2 GC-rich sequence DNA-binding factor 2
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GRB10 growth factor receptor-bound protein 10
HAUS6 HAUS augmin-like complex, subunit 6
HHEX hematopoietically expressed homeobox
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HOOK1 hook microtubule-tethering protein 1
HSF2 heat shock transcription factor 2
HSPA13 heat shock protein 70kDa family, member 13
IL1RAP interleukin 1 receptor accessory protein
ITFG2 integrin alpha FG-GAP repeat containing 2
KIAA0141 KIAA0141
KLC2 kinesin light chain 2
KLF12 Kruppel-like factor 12
KLHL20 kelch-like family member 20
LIG3 ligase III, DNA, ATP-dependent
LMF1 lipase maturation factor 1
LUC7L3 LUC7-like 3 (S. cerevisiae)
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP4 microtubule-associated protein 4
MDM1 Mdm1 nuclear protein homolog (mouse)
MED4 mediator complex subunit 4
MED6 mediator complex subunit 6
MET MET proto-oncogene, receptor tyrosine kinase
MLF1 myeloid leukemia factor 1
MPP1 membrane protein, palmitoylated 1, 55kDa
NADK NAD kinase
NECAP1 NECAP endocytosis associated 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR2C1 nuclear receptor subfamily 2, group C, member 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NUP50 nucleoporin 50kDa
OCEL1 occludin/ELL domain containing 1
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PDS5A PDS5 cohesin associated factor A
PELI1 pellino E3 ubiquitin protein ligase 1
PGAP1 post-GPI attachment to proteins 1
PICALM phosphatidylinositol binding clathrin assembly protein
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PMM2 phosphomannomutase 2
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PPT2 palmitoyl-protein thioesterase 2
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RAB29 RAB29, member RAS oncogene family
RARA retinoic acid receptor, alpha
RBM12 RNA binding motif protein 12
RC3H2 ring finger and CCCH-type domains 2
RPS10P5 ribosomal protein S10 pseudogene 5
RRP1B ribosomal RNA processing 1B
RUFY3 RUN and FYVE domain containing 3
RWDD3 RWD domain containing 3
SCYL2 SCY1-like 2 (S. cerevisiae)
SENP6 SUMO1/sentrin specific peptidase 6
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC25A44 solute carrier family 25, member 44
SNX1 sorting nexin 1
SON SON DNA binding protein
SP100 SP100 nuclear antigen
TGM2 transglutaminase 2
TMBIM1 transmembrane BAX inhibitor motif containing 1
TNPO2 transportin 2
TPP2 tripeptidyl peptidase II
TRRAP transformation/transcription domain-associated protein
TSPAN31 tetraspanin 31
TTC33 tetratricopeptide repeat domain 33
UBE2D1 ubiquitin-conjugating enzyme E2D 1
WDR43 WD repeat domain 43
WNK1 WNK lysine deficient protein kinase 1
YTHDC2 YTH domain containing 2
ZNF552 zinc finger protein 552

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABI3BP ABI family, member 3 (NESH) binding protein
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANKRD36B ankyrin repeat domain 36B
ASB13 ankyrin repeat and SOCS box containing 13
AXIN1 axin 1
BPGM 2,3-bisphosphoglycerate mutase
C16ORF62 chromosome 16 open reading frame 62
C19ORF54 chromosome 19 open reading frame 54
C3 complement component 3
C9ORF91 chromosome 9 open reading frame 91
CARD8 caspase recruitment domain family, member 8
CCDC25 coiled-coil domain containing 25
CFAP44 cilia and flagella associated protein 44
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCAF4 DDB1 and CUL4 associated factor 4
DFNB31 deafness, autosomal recessive 31
DOCK1 dedicator of cytokinesis 1
EIF5 eukaryotic translation initiation factor 5
FZD4 frizzled class receptor 4
GAMT guanidinoacetate N-methyltransferase
GBAP1 glucosidase, beta, acid pseudogene 1
GPATCH2 G patch domain containing 2
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HCG4 HLA complex group 4 (non-protein coding)
HDAC7 histone deacetylase 7
HINFP histone H4 transcription factor
HPS6 Hermansky-Pudlak syndrome 6
HSPA1A heat shock 70kDa protein 1A
HYI hydroxypyruvate isomerase (putative)
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
INTS6 integrator complex subunit 6
KIAA0355 KIAA0355
KLF2 Kruppel-like factor 2
KLF7 Kruppel-like factor 7 (ubiquitous)
KPTN kaptin (actin binding protein)
KRCC1 lysine-rich coiled-coil 1
LMBR1L limb development membrane protein 1-like
LONP2 lon peptidase 2, peroxisomal
MAGEF1 melanoma antigen family F1
MCTP1 multiple C2 domains, transmembrane 1
MFSD11 major facilitator superfamily domain containing 11
MGC12488
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MTCL1 microtubule crosslinking factor 1
NADSYN1 NAD synthetase 1
NDRG4 NDRG family member 4
NINJ1 ninjurin 1
NTSR1 neurotensin receptor 1 (high affinity)
NUPR1 nuclear protein, transcriptional regulator, 1
PDZD2 PDZ domain containing 2
PLCD1 phospholipase C, delta 1
PLD3 phospholipase D family, member 3
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
POM121 POM121 transmembrane nucleoporin
PPP1R10 protein phosphatase 1, regulatory subunit 10
PROSER1 proline and serine rich 1
RBM15B RNA binding motif protein 15B
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RPGR retinitis pigmentosa GTPase regulator
SETD1B SET domain containing 1B
SETD8 SET domain containing (lysine methyltransferase) 8
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC38A10 solute carrier family 38, member 10
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TAOK1 TAO kinase 1
TBC1D19 TBC1 domain family, member 19
TCTN1 tectonic family member 1
TENM4 teneurin transmembrane protein 4
TESK1 testis-specific kinase 1
THBS3 thrombospondin 3
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TMEM104 transmembrane protein 104
TOE1 target of EGR1, member 1 (nuclear)
TPCN1 two pore segment channel 1
TRIM9 tripartite motif containing 9
TTC17 tetratricopeptide repeat domain 17
TTC26 tetratricopeptide repeat domain 26
TUBA3C tubulin, alpha 3c
VEGFB vascular endothelial growth factor B
ZBTB25 zinc finger and BTB domain containing 25
ZDHHC11 zinc finger, DHHC-type containing 11
ZFYVE16 zinc finger, FYVE domain containing 16
ZMAT5 zinc finger, matrin-type 5
ZNF189 zinc finger protein 189
ZNF23 zinc finger protein 23
ZNF232 zinc finger protein 232
ZNF350 zinc finger protein 350
ZNF574 zinc finger protein 574
ZNF85 zinc finger protein 85
ZSCAN16 zinc finger and SCAN domain containing 16