ARF6 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description ADP-ribosylation factor 6|This gene encodes a member of the human ARF gene family, which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 382)
External Link https://ncbi.nlm.nih.gov/gene/382
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Genes

500 genes differentially expressed following the ARF6 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
KRT14 keratin 14, type I 0.0276928
HSPB1 heat shock 27kDa protein 1 0.0258428
IFI44L interferon-induced protein 44-like 0.0211326
CRABP2 cellular retinoic acid binding protein 2 0.01967
SLPI secretory leukocyte peptidase inhibitor 0.0177414
KRT5 keratin 5, type II 0.0177212
ASS1 argininosuccinate synthase 1 0.0174896
ATF3 activating transcription factor 3 0.0174448
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.0174375
IFI44 interferon-induced protein 44 0.0171011
AQP3 aquaporin 3 (Gill blood group) 0.0168935
S100A9 S100 calcium binding protein A9 0.0167967
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.0166278
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.0163419
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.0159463
CRYAB crystallin, alpha B 0.0159138
IFI27 interferon, alpha-inducible protein 27 0.015781
CAV1 caveolin 1, caveolae protein, 22kDa 0.0154513
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.0153908
S100A8 S100 calcium binding protein A8 0.0153537
KLK10 kallikrein-related peptidase 10 0.0153002
MT1X metallothionein 1X 0.0151974
CD9 CD9 molecule 0.0148634
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.0146927
RGCC regulator of cell cycle 0.0145997
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.0145465
PITX3 paired-like homeodomain 3 0.014165
S100A7 S100 calcium binding protein A7 0.0141352
TUBB2A tubulin, beta 2A class IIa 0.0141305
HIST1H2BD histone cluster 1, H2bd 0.01403
LAMP3 lysosomal-associated membrane protein 3 0.0140032
RBM34 RNA binding motif protein 34 0.0139729
ZBED2 zinc finger, BED-type containing 2 0.0139628
KLF6 Kruppel-like factor 6 0.0139372
HIST1H2AC histone cluster 1, H2ac 0.0136706
S100A2 S100 calcium binding protein A2 0.0136244
IGLL1 immunoglobulin lambda-like polypeptide 1 0.0133836
FGFBP1 fibroblast growth factor binding protein 1 0.0133321
DOK5 docking protein 5 0.0132062
DEFB1 defensin, beta 1 0.0130331
RSAD2 radical S-adenosyl methionine domain containing 2 0.0129409
MME membrane metallo-endopeptidase 0.0127947
CLIC5 chloride intracellular channel 5 0.0127731
INHBA inhibin, beta A 0.0125675
KLK11 kallikrein-related peptidase 11 0.0124936
LRRC17 leucine rich repeat containing 17 0.0123988
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.0123598
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 0.0122842
CTSD cathepsin D 0.0122631
XPO7 exportin 7 0.0122241
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.012164
IGFBP5 insulin-like growth factor binding protein 5 0.0121118
LYPD1 LY6/PLAUR domain containing 1 0.0119672
TSPAN7 tetraspanin 7 0.011817
MMP10 matrix metallopeptidase 10 0.011803
AREG amphiregulin 0.0117633
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.0117036
CCN2 cellular communication network factor 2 0.0114386
BCAT1 branched chain amino-acid transaminase 1, cytosolic 0.0113941
SPRR1B small proline-rich protein 1B 0.0112927
MT2A metallothionein 2A 0.0112144
UBE2L6 ubiquitin-conjugating enzyme E2L 6 0.0111279
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.0111218
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.0111169
KLF7 Kruppel-like factor 7 (ubiquitous) 0.0110283
ACTA2 actin, alpha 2, smooth muscle, aorta 0.0110064
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.0109992
CASP7 caspase 7, apoptosis-related cysteine peptidase 0.0109389
KRT15 keratin 15, type I 0.0109309
JPT1 Jupiter microtubule associated homolog 1 0.0109014
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 0.0108987
WDR7 WD repeat domain 7 0.0107991
EGR1 early growth response 1 0.0107899
CD93 CD93 molecule 0.0107214
ANXA1 annexin A1 0.0107126
SGCE sarcoglycan, epsilon 0.0107078
TUBB2B tubulin, beta 2B class IIb 0.0106979
FERMT1 fermitin family member 1 0.010666
KRT6A keratin 6A, type II 0.0105852
SIRT3 sirtuin 3 0.0105773
IFITM1 interferon induced transmembrane protein 1 0.0105439
CRABP1 cellular retinoic acid binding protein 1 0.0104243
QPRT quinolinate phosphoribosyltransferase 0.010357
KRT1 keratin 1, type II 0.0103422
PLS3 plastin 3 0.0103214
CPM carboxypeptidase M 0.0102912
CFI complement factor I 0.0102749
FABP4 fatty acid binding protein 4, adipocyte 0.0102582
CHEK1 checkpoint kinase 1 0.0102486
TRIM29 tripartite motif containing 29 0.0101933
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 0.0101857
VSIG4 V-set and immunoglobulin domain containing 4 0.0101734
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 0.010139
CLDN10 claudin 10 0.0101295
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.0100896
GPX7 glutathione peroxidase 7 0.010087
MT1H metallothionein 1H 0.0100684
MALL mal, T-cell differentiation protein-like 0.0100361
BMP2 bone morphogenetic protein 2 0.0100224
SAMD9 sterile alpha motif domain containing 9 0.0100201
PI3 peptidase inhibitor 3, skin-derived 0.00998525
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.00993297
RCAN1 regulator of calcineurin 1 0.0098884
MYH10 myosin, heavy chain 10, non-muscle 0.00987062
BPGM 2,3-bisphosphoglycerate mutase 0.00986945
ZNF706 zinc finger protein 706 0.00984148
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.00975013
DSP desmoplakin 0.00972426
C10ORF10 chromosome 10 open reading frame 10 0.00971197
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.00967804
TSPAN3 tetraspanin 3 0.00967696
ACLY ATP citrate lyase 0.00967358
YIPF5 Yip1 domain family, member 5 0.00955861
KIFAP3 kinesin-associated protein 3 0.00955491
RANBP9 RAN binding protein 9 0.00952222
PEG10 paternally expressed 10 0.00951993
SPARCL1 SPARC-like 1 (hevin) 0.00951433
NOTCH1 notch 1 0.00951241
MT1HL1 metallothionein 1H-like 1 0.00949626
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.0094898
KLK5 kallikrein-related peptidase 5 0.00948956
AOC1 amine oxidase, copper containing 1 0.00947526
IFI16 interferon, gamma-inducible protein 16 0.00947109
CLEC2B C-type lectin domain family 2, member B 0.0094368
TMEM230 transmembrane protein 230 0.00940433
CCL20 chemokine (C-C motif) ligand 20 0.00937263
EMP1 epithelial membrane protein 1 0.00935416
C1QB complement component 1, q subcomponent, B chain 0.00934617
NEFM neurofilament, medium polypeptide 0.00934332
GPM6B glycoprotein M6B 0.00932627
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.00929469
FAM110B family with sequence similarity 110, member B 0.00929225
MX1 MX dynamin-like GTPase 1 0.00929038
BTG3 BTG family, member 3 0.00928536
PLAT plasminogen activator, tissue 0.00926164
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.00925096
IFITM2 interferon induced transmembrane protein 2 0.00921318
VPREB1 pre-B lymphocyte 1 0.00920025
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00919983
KCTD12 potassium channel tetramerization domain containing 12 0.00915062
DENND1B DENN/MADD domain containing 1B 0.00914189
IFI6 interferon, alpha-inducible protein 6 0.00913829
RHCG Rh family, C glycoprotein 0.00911486
TMEM140 transmembrane protein 140 0.00910436
BAMBI BMP and activin membrane-bound inhibitor 0.00910144
FAR2 fatty acyl CoA reductase 2 0.00907644
BGN biglycan 0.00907088
MGP matrix Gla protein 0.00906564
ZFP36 ZFP36 ring finger protein 0.00894994
HTRA1 HtrA serine peptidase 1 0.00894019
AQP1 aquaporin 1 (Colton blood group) 0.00891094
ISG15 ISG15 ubiquitin-like modifier 0.00888226
KLK7 kallikrein-related peptidase 7 0.00884299
SEPP1 selenoprotein P, plasma, 1 0.00882841
TMEM176B transmembrane protein 176B 0.00878607
FAM107A family with sequence similarity 107, member A 0.00878124
MT1G metallothionein 1G 0.00873137
PRTN3 proteinase 3 0.00872116
MZB1 marginal zone B and B1 cell-specific protein 0.00870798
PCOLCE2 procollagen C-endopeptidase enhancer 2 0.00870753
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.0087041
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.00870013
RBMS1 RNA binding motif, single stranded interacting protein 1 0.00869187
WT1 Wilms tumor 1 0.00869065
HBEGF heparin-binding EGF-like growth factor 0.00864247
MUC16 mucin 16, cell surface associated 0.00864125
MSR1 macrophage scavenger receptor 1 0.00862883
TCTA T-cell leukemia translocation altered 0.00862735
REEP5 receptor accessory protein 5 0.00855362
KRT23 keratin 23, type I 0.00852694
TRIM22 tripartite motif containing 22 0.00850151
STON1 stonin 1 0.00847227
ADAR adenosine deaminase, RNA-specific 0.00846477
MX2 MX dynamin-like GTPase 2 0.00838017
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.00837828
KIAA0355 KIAA0355 0.00835308
PNMA2 paraneoplastic Ma antigen 2 0.00834788
TPM4 tropomyosin 4 0.00817869
RGS4 regulator of G-protein signaling 4 0.00812464
IFI35 interferon-induced protein 35 0.00812067
PRNP prion protein 0.00810282
IL10RB interleukin 10 receptor, beta 0.00809723
IL1A interleukin 1, alpha 0.00809636
ISG20 interferon stimulated exonuclease gene 20kDa 0.00809421
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.00808764
ADIRF adipogenesis regulatory factor 0.00808396
KRT16 keratin 16, type I 0.00806157
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.00803678
KLK8 kallikrein-related peptidase 8 0.00800885
RSL1D1 ribosomal L1 domain containing 1 0.00797977
KRT17 keratin 17, type I 0.00797933
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.00795509
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.00795149
ZNF271P zinc finger protein 271, pseudogene 0.00795132
OLFML3 olfactomedin-like 3 0.00793594
CAPRIN1 cell cycle associated protein 1 0.00793101
CFB complement factor B 0.0079123
EMP2 epithelial membrane protein 2 0.00790901
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.00790229
ACAT1 acetyl-CoA acetyltransferase 1 0.00788975
KL klotho 0.00788566
RTP4 receptor (chemosensory) transporter protein 4 0.00787654
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 0.00785618
PSAT1 phosphoserine aminotransferase 1 0.00783802
F8 coagulation factor VIII, procoagulant component 0.00783653
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 0.00780813
PELI1 pellino E3 ubiquitin protein ligase 1 0.0077858
CXADR coxsackie virus and adenovirus receptor 0.00778448
FKBP1A FK506 binding protein 1A, 12kDa 0.00777717
BPHL biphenyl hydrolase-like (serine hydrolase) 0.00777475
ITM2C integral membrane protein 2C 0.00776169
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.00775466
TUBB6 tubulin, beta 6 class V 0.00773768
LHFP lipoma HMGIC fusion partner 0.00773722
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 0.00773541
SELE selectin E 0.00770846
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.00770012
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.00768508
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 0.0076792
ACOT9 acyl-CoA thioesterase 9 0.007679
EXOC5 exocyst complex component 5 0.00767729
DIRAS3 DIRAS family, GTP-binding RAS-like 3 0.00767669
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) 0.00764289
FRMD4B FERM domain containing 4B 0.00764174
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 0.0076397
RFTN1 raftlin, lipid raft linker 1 0.00762824
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.00762751
CXCL8 chemokine (C-X-C motif) ligand 8 0.00761495
GAP43 growth associated protein 43 0.00761254
NREP neuronal regeneration related protein 0.00758441
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 0.00755814
MAST4 microtubule associated serine/threonine kinase family member 4 0.00754159
CLIC4 chloride intracellular channel 4 0.00752074
IL1B interleukin 1, beta 0.00751963
IFITM3 interferon induced transmembrane protein 3 0.00748448
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 0.0074669
NMRK1 nicotinamide riboside kinase 1 0.00746636
ACOT13 acyl-CoA thioesterase 13 0.00745649
WNK1 WNK lysine deficient protein kinase 1 0.00745203
MT1E metallothionein 1E 0.00742617
PDZK1IP1 PDZK1 interacting protein 1 0.00742401
SEC14L1 SEC14-like 1 (S. cerevisiae) 0.00740875
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.00740712
ADAT1 adenosine deaminase, tRNA-specific 1 0.00739738
CNIH4 cornichon family AMPA receptor auxiliary protein 4 0.0073922
JAG1 jagged 1 0.00737329
EGR3 early growth response 3 0.00736295
PIEZO2 piezo-type mechanosensitive ion channel component 2 0.00734985
PDGFD platelet derived growth factor D 0.00732217
SPRR1A small proline-rich protein 1A 0.00731503

decreased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 -0.029045
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.0219146
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.0205811
TGFBI transforming growth factor, beta-induced, 68kDa -0.0202807
TFF1 trefoil factor 1 -0.0170086
CHP1 calcineurin-like EF-hand protein 1 -0.0168993
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0161322
CST3 cystatin C -0.0159858
NTS neurotensin -0.0150412
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.0142936
TNC tenascin C -0.0141463
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.013944
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.0138724
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.0137504
TSPYL5 TSPY-like 5 -0.013635
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 -0.0134597
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.0132651
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.0132268
PHACTR2 phosphatase and actin regulator 2 -0.0131424
CCL19 chemokine (C-C motif) ligand 19 -0.0130838
TFF3 trefoil factor 3 (intestinal) -0.0128836
TOX3 TOX high mobility group box family member 3 -0.0126605
GOLGA8A golgin A8 family, member A -0.0126539
EPHB2 EPH receptor B2 -0.0124596
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -0.0124227
LYN LYN proto-oncogene, Src family tyrosine kinase -0.0123393
RAD23B RAD23 homolog B (S. cerevisiae) -0.0122619
CTSH cathepsin H -0.0122402
AGR2 anterior gradient 2 -0.0121388
COL4A5 collagen, type IV, alpha 5 -0.0120852
MOCOS molybdenum cofactor sulfurase -0.0118061
LGALS1 lectin, galactoside-binding, soluble, 1 -0.0117279
PNKP polynucleotide kinase 3'-phosphatase -0.0117039
BASP1 brain abundant, membrane attached signal protein 1 -0.0116255
TPD52L1 tumor protein D52-like 1 -0.0116195
LGALS13 lectin, galactoside-binding, soluble, 13 -0.011517
LUM lumican -0.0113765
PROM1 prominin 1 -0.0112828
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.0111504
TBX3 T-box 3 -0.0108677
REG1A regenerating islet-derived 1 alpha -0.0108504
LYZ lysozyme -0.0106845
REG3A regenerating islet-derived 3 alpha -0.010676
RUFY3 RUN and FYVE domain containing 3 -0.0106645
MTCL1 microtubule crosslinking factor 1 -0.0105125
FGFR3 fibroblast growth factor receptor 3 -0.0104534
HOXC6 homeobox C6 -0.0103553
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.0102544
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.0101988
TESC tescalcin -0.0101408
PRDX2 peroxiredoxin 2 -0.0101355
COL15A1 collagen, type XV, alpha 1 -0.00995698
SSBP2 single-stranded DNA binding protein 2 -0.00991918
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 -0.00990161
BTBD3 BTB (POZ) domain containing 3 -0.00977174
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.00971573
PMP22 peripheral myelin protein 22 -0.00968972
PLPP2 phospholipid phosphatase 2 -0.0096043
LSR lipolysis stimulated lipoprotein receptor -0.00954681
H2AX H2A.X variant histone -0.00953562
TIA1 TIA1 cytotoxic granule-associated RNA binding protein -0.00953066
F5 coagulation factor V (proaccelerin, labile factor) -0.00952645
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -0.00927418
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 -0.00922306
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -0.00920426
MSMB microseminoprotein, beta- -0.00916869
UBE2S ubiquitin-conjugating enzyme E2S -0.00914505
CCR7 chemokine (C-C motif) receptor 7 -0.00912723
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2 -0.00911126
SPINK4 serine peptidase inhibitor, Kazal type 4 -0.00904662
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 -0.00903174
LUC7L3 LUC7-like 3 (S. cerevisiae) -0.00902856
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide -0.00899296
GSTT1 glutathione S-transferase theta 1 -0.00898659
EFHD2 EF-hand domain family, member D2 -0.00898432
PBX1 pre-B-cell leukemia homeobox 1 -0.00889026
CGA glycoprotein hormones, alpha polypeptide -0.0088671
PCDH9 protocadherin 9 -0.00882981
FA2H fatty acid 2-hydroxylase -0.00882453
AMD1 adenosylmethionine decarboxylase 1 -0.00881846
DACH1 dachshund family transcription factor 1 -0.00881478
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -0.00879445
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 -0.00876913
ANXA10 annexin A10 -0.00874683
IKZF1 IKAROS family zinc finger 1 (Ikaros) -0.0087345
PGC progastricsin (pepsinogen C) -0.00872075
PFKL phosphofructokinase, liver -0.00869807
HDAC1 histone deacetylase 1 -0.00869575
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog -0.00864112
INTS6 integrator complex subunit 6 -0.00860998
MEF2C myocyte enhancer factor 2C -0.00859268
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) -0.00858791
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 -0.00856731
NPM3 nucleophosmin/nucleoplasmin 3 -0.00854416
CLCA1 chloride channel accessory 1 -0.00853054
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.00852314
CPVL carboxypeptidase, vitellogenic-like -0.0085204
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 -0.00851412
NADK NAD kinase -0.00848106
GPX2 glutathione peroxidase 2 -0.00848045
MMP9 matrix metallopeptidase 9 -0.00846932
GATA2 GATA binding protein 2 -0.00844147
HEPH hephaestin -0.00837717
MTA1 metastasis associated 1 -0.00830018
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -0.00829951
MLPH melanophilin -0.0082535
SFRP1 secreted frizzled-related protein 1 -0.0082516
SOX9 SRY (sex determining region Y)-box 9 -0.00822566
CNTNAP2 contactin associated protein-like 2 -0.00822323
SUB1 SUB1 homolog (S. cerevisiae) -0.00821383
FMO5 flavin containing monooxygenase 5 -0.00820604
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) -0.00819114
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -0.00816263
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.00815389
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.00815204
ADAM28 ADAM metallopeptidase domain 28 -0.00815166
MICALL2 MICAL-like 2 -0.00813219
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) -0.00812957
AKT1 v-akt murine thymoma viral oncogene homolog 1 -0.008101
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 -0.00805319
CLASRP CLK4-associating serine/arginine rich protein -0.00800462
MYO6 myosin VI -0.00798675
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H -0.00798224
FANCL Fanconi anemia, complementation group L -0.00797242
GAL galanin/GMAP prepropeptide -0.00795914
TGM2 transglutaminase 2 -0.00795834
SORBS2 sorbin and SH3 domain containing 2 -0.00793244
WTAP Wilms tumor 1 associated protein -0.00792853
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant -0.00790189
SH3GLB2 SH3-domain GRB2-like endophilin B2 -0.00789951
NOTCH2 notch 2 -0.00788856
DLK1 delta-like 1 homolog (Drosophila) -0.00786425
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -0.00780892
CDKN2A cyclin-dependent kinase inhibitor 2A -0.00777975
DEFA5 defensin, alpha 5, Paneth cell-specific -0.00776326
MED23 mediator complex subunit 23 -0.00776268
NUP43 nucleoporin 43kDa -0.00775794
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 -0.00773302
CSK c-src tyrosine kinase -0.00772067
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 -0.00771792
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 -0.00770212
GSN gelsolin -0.00768625
STX1A syntaxin 1A (brain) -0.00767666
GATA6 GATA binding protein 6 -0.0076706
NAXD NAD(P)HX dehydratase -0.00765626
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.00764959
ISL1 ISL LIM homeobox 1 -0.00764228
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 -0.00764016
ZBTB38 zinc finger and BTB domain containing 38 -0.0076206
AKAP8 A kinase (PRKA) anchor protein 8 -0.00761975
PRC1 protein regulator of cytokinesis 1 -0.00757941
GSTA1 glutathione S-transferase alpha 1 -0.00757672
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) -0.00754758
EHBP1L1 EH domain binding protein 1-like 1 -0.00754164
DGKZ diacylglycerol kinase, zeta -0.00752552
SDC2 syndecan 2 -0.00750992
TARDBP TAR DNA binding protein -0.00749837
HOXA10 homeobox A10 -0.00749231
PRKCB protein kinase C, beta -0.00745364
PHYH phytanoyl-CoA 2-hydroxylase -0.00739865
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae) -0.0073958
TULP4 tubby like protein 4 -0.00739069
PRKCZ protein kinase C, zeta -0.00737304
PRMT1 protein arginine methyltransferase 1 -0.00735638
EMID1 EMI domain containing 1 -0.00734398
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -0.00733795
NDRG2 NDRG family member 2 -0.00730926
ZWINT ZW10 interacting kinetochore protein -0.00730468
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00729929
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.00727627
SIDT2 SID1 transmembrane family, member 2 -0.00726477
ECHDC2 enoyl CoA hydratase domain containing 2 -0.0072586
MRPS2 mitochondrial ribosomal protein S2 -0.00724895
PRAME preferentially expressed antigen in melanoma -0.0072413
MAN2C1 mannosidase, alpha, class 2C, member 1 -0.00724092
MANSC1 MANSC domain containing 1 -0.00723959
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3 -0.00723519
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.0072163
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.00720724
CD40 CD40 molecule, TNF receptor superfamily member 5 -0.00719953
P4HB prolyl 4-hydroxylase, beta polypeptide -0.00719816
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 -0.00719712
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 -0.00718391
TMSB15A thymosin beta 15a -0.00718106
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00717882
COQ8A coenzyme Q8A -0.00717614
FGR FGR proto-oncogene, Src family tyrosine kinase -0.00717087
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -0.0071605
TNIK TRAF2 and NCK interacting kinase -0.00715727
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 -0.00715702
MMP12 matrix metallopeptidase 12 -0.00714151
AXL AXL receptor tyrosine kinase -0.00713781
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) -0.00712882
MDM1 Mdm1 nuclear protein homolog (mouse) -0.00712721
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1 -0.00712003
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A -0.00708435
CEP43 centrosomal protein 43 -0.00708228
PIGT phosphatidylinositol glycan anchor biosynthesis, class T -0.00707034
FUCA1 fucosidase, alpha-L- 1, tissue -0.00706817
RHOBTB3 Rho-related BTB domain containing 3 -0.00706315
SCD5 stearoyl-CoA desaturase 5 -0.00704824
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 -0.00703622
CENPM centromere protein M -0.0070349
LMNB2 lamin B2 -0.00702789
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 -0.00700993
SF3B5 splicing factor 3b, subunit 5, 10kDa -0.00700812
PPA2 pyrophosphatase (inorganic) 2 -0.007005
SPAG6 sperm associated antigen 6 -0.0069972
IL7 interleukin 7 -0.0069912
PDZRN3 PDZ domain containing ring finger 3 -0.00698972
PEX11A peroxisomal biogenesis factor 11 alpha -0.00698782
MOK MOK protein kinase -0.00697708
ADAMDEC1 ADAM-like, decysin 1 -0.00694494
AKAP7 A kinase (PRKA) anchor protein 7 -0.006933
PTPRM protein tyrosine phosphatase, receptor type, M -0.00691926
CCR2 chemokine (C-C motif) receptor 2 -0.00691704
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 -0.00689815
UBP1 upstream binding protein 1 (LBP-1a) -0.0068964
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase -0.00689463
TMEM259 transmembrane protein 259 -0.00688544
FBL fibrillarin -0.00685971
LOC283683 uncharacterized LOC283683 -0.00685737
WWOX WW domain containing oxidoreductase -0.0068544
LY75 lymphocyte antigen 75 -0.00684601
METRN meteorin, glial cell differentiation regulator -0.0068329
FABP6 fatty acid binding protein 6, ileal -0.00681834
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) -0.00680136
HBB hemoglobin, beta -0.00678978
PNISR PNN-interacting serine/arginine-rich protein -0.0067889
MMP3 matrix metallopeptidase 3 -0.0067769
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) -0.00677504
SORD sorbitol dehydrogenase -0.00676648
ARGLU1 arginine and glutamate rich 1 -0.00676361
TRPA1 transient receptor potential cation channel, subfamily A, member 1 -0.0067621
P3H2 prolyl 3-hydroxylase 2 -0.00675494
CDCP1 CUB domain containing protein 1 -0.00674192
IRF8 interferon regulatory factor 8 -0.00674018
SLC44A4 solute carrier family 44, member 4 -0.0067397
S100A4 S100 calcium binding protein A4 -0.00673675
GREM1 gremlin 1, DAN family BMP antagonist -0.00671929
EDRF1 erythroid differentiation regulatory factor 1 -0.0067187
PLXNC1 plexin C1 -0.00670377
DEFA6 defensin, alpha 6, Paneth cell-specific -0.0067031
SEC23A Sec23 homolog A (S. cerevisiae) -0.00669925
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 -0.00667138
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae) -0.00666629
ACO1 aconitase 1, soluble -0.00664844
TXNIP thioredoxin interacting protein -0.0066431
PIGB phosphatidylinositol glycan anchor biosynthesis, class B -0.0066364
TLE4 transducin-like enhancer of split 4 -0.00663343