| Dataset | NURSA Protein-Protein Interactions |
| Category | proteomics |
| Type | interacting protein |
| Description | aryl hydrocarbon receptor nuclear translocator|This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013] (NCBI Entrez Gene Database, 405) |
| External Link | http://www.ncbi.nlm.nih.gov/gene/405 |
| Similar Terms | |
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6 interacting proteins for ARNT from the NURSA Protein-Protein Interactions dataset.
