ARNT Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description aryl hydrocarbon receptor nuclear translocator|This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013] (NCBI Entrez Gene Database, 405)
External Link http://www.ncbi.nlm.nih.gov/gene/405
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Genes

228 interacting proteins for ARNT from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
AGO1 argonaute RISC catalytic component 1
AGO3 argonaute RISC catalytic component 3
AHR aryl hydrocarbon receptor
AHRR aryl-hydrocarbon receptor repressor
AIP aryl hydrocarbon receptor interacting protein
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALYREF Aly/REF export factor
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
BANP BTG3 associated nuclear protein
BCLAF1 BCL2-associated transcription factor 1
BRCA1 breast cancer 1, early onset
BYSL bystin-like
C14ORF166 chromosome 14 open reading frame 166
C1QBP complement component 1, q subcomponent binding protein
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1
CAPZB capping protein (actin filament) muscle Z-line, beta
CBX4 chromobox homolog 4
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2A2 casein kinase 2, alpha prime polypeptide
CSNK2B casein kinase 2, beta polypeptide
CUL2 cullin 2
CUL4B cullin 4B
DAP3 death associated protein 3
DDA1 DET1 and DDB1 associated 1
DDB1 damage-specific DNA binding protein 1, 127kDa
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DIABLO diablo, IAP-binding mitochondrial protein
DYNLL1 dynein, light chain, LC8-type 1
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EIF3A eukaryotic translation initiation factor 3, subunit A
EIF3CL eukaryotic translation initiation factor 3, subunit C-like
EIF3E eukaryotic translation initiation factor 3, subunit E
EIF3F eukaryotic translation initiation factor 3, subunit F
EIF3H eukaryotic translation initiation factor 3, subunit H
EIF3I eukaryotic translation initiation factor 3, subunit I
EIF3M eukaryotic translation initiation factor 3, subunit M
EIF4EBP3 eukaryotic translation initiation factor 4E binding protein 3
ELAVL1 ELAV like RNA binding protein 1
EP300 E1A binding protein p300
EPAS1 endothelial PAS domain protein 1
ERH enhancer of rudimentary homolog (Drosophila)
ESR1 estrogen receptor 1
EWSR1 EWS RNA-binding protein 1
FAF1 Fas (TNFRSF6) associated factor 1
FAM151B family with sequence similarity 151, member B
FNTA farnesyltransferase, CAAX box, alpha
GMNN geminin, DNA replication inhibitor
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GPC4 glypican 4
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GTF2I general transcription factor IIi
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa
H2AFJ H2A histone family, member J
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HBA2 hemoglobin, alpha 2
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST1H1C histone cluster 1, H1c
HIST1H1D histone cluster 1, H1d
HIST1H2BN histone cluster 1, H2bn
HIST1H4F histone cluster 1, H4f
HIST2H2BE histone cluster 2, H2be
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HNRNPM heterogeneous nuclear ribonucleoprotein M
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA1B heat shock 70kDa protein 1B
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
IRAK4 interleukin-1 receptor-associated kinase 4
ITCH itchy E3 ubiquitin protein ligase
KDM1A lysine (K)-specific demethylase 1A
MAMDC2 MAM domain containing 2
MRPL12 mitochondrial ribosomal protein L12
MRPL17 mitochondrial ribosomal protein L17
MRPS22 mitochondrial ribosomal protein S22
MRPS23 mitochondrial ribosomal protein S23
MRPS28 mitochondrial ribosomal protein S28
MRPS35 mitochondrial ribosomal protein S35
MTA3 metastasis associated 1 family, member 3
MYH10 myosin, heavy chain 10, non-muscle
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit
NAP1L1 nucleosome assembly protein 1-like 1
NASP nuclear autoantigenic sperm protein (histone-binding)
NCOA1 nuclear receptor coactivator 1
NCOA2 nuclear receptor coactivator 2
NCOA7 nuclear receptor coactivator 7
NCOR2 nuclear receptor corepressor 2
NPAS1 neuronal PAS domain protein 1
NPAS4 neuronal PAS domain protein 4
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NQO2 NAD(P)H dehydrogenase, quinone 2
OBSL1 obscurin-like 1
PABPC1 poly(A) binding protein, cytoplasmic 1
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PML promyelocytic leukemia
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
POLR2H polymerase (RNA) II (DNA directed) polypeptide H
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PRPF19 pre-mRNA processing factor 19
PRPF8 pre-mRNA processing factor 8
PTGES3 prostaglandin E synthase 3 (cytosolic)
RB1 retinoblastoma 1
RBX1 ring-box 1, E3 ubiquitin protein ligase
RPL10 ribosomal protein L10
RPL10A ribosomal protein L10a
RPL11 ribosomal protein L11
RPL14 ribosomal protein L14
RPL18 ribosomal protein L18
RPL18A ribosomal protein L18a
RPL22 ribosomal protein L22
RPL23 ribosomal protein L23
RPL23A ribosomal protein L23a
RPL24 ribosomal protein L24
RPL27 ribosomal protein L27
RPL27A ribosomal protein L27a
RPL28 ribosomal protein L28
RPL29 ribosomal protein L29
RPL30 ribosomal protein L30
RPL31 ribosomal protein L31
RPL32 ribosomal protein L32
RPL36 ribosomal protein L36
RPL4 ribosomal protein L4
RPL6 ribosomal protein L6
RPL7 ribosomal protein L7
RPL8 ribosomal protein L8
RPLP0 ribosomal protein, large, P0
RPLP2 ribosomal protein, large, P2
RPS11 ribosomal protein S11
RPS12 ribosomal protein S12
RPS13 ribosomal protein S13
RPS14 ribosomal protein S14
RPS15A ribosomal protein S15a
RPS16 ribosomal protein S16
RPS19 ribosomal protein S19
RPS2 ribosomal protein S2
RPS20 ribosomal protein S20
RPS23 ribosomal protein S23
RPS25 ribosomal protein S25
RPS27L ribosomal protein S27-like
RPS3 ribosomal protein S3
RPS4X ribosomal protein S4, X-linked
RPS5 ribosomal protein S5
RPS6 ribosomal protein S6
RPS8 ribosomal protein S8
RPS9 ribosomal protein S9
RPSA ribosomal protein SA
RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase
S100A8 S100 calcium binding protein A8
SART3 squamous cell carcinoma antigen recognized by T cells 3
SENP6 SUMO1/sentrin specific peptidase 6
SERBP1 SERPINE1 mRNA binding protein 1
SET SET nuclear proto-oncogene
SIM1 single-minded family bHLH transcription factor 1
SIM2 single-minded family bHLH transcription factor 2
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SMAD6 SMAD family member 6
SMAD9 SMAD family member 9
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1)
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa
SP1 Sp1 transcription factor
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STRBP spermatid perinuclear RNA binding protein
SUMO1 small ubiquitin-like modifier 1
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae)
TBL3 transducin (beta)-like 3
TCEAL1 transcription elongation factor A (SII)-like 1
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
THRAP3 thyroid hormone receptor associated protein 3
TICAM2 toll-like receptor adaptor molecule 2
TMED1 transmembrane emp24 protein transport domain containing 1
TMED10 transmembrane emp24-like trafficking protein 10 (yeast)
TMED2 transmembrane emp24 domain trafficking protein 2
TMED7 transmembrane emp24 protein transport domain containing 7
TMED9 transmembrane emp24 protein transport domain containing 9
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNRC6B trinucleotide repeat containing 6B
TRIM11 tripartite motif containing 11
TRIP11 thyroid hormone receptor interactor 11
TSLIG3A tRNA splicing ligase complex subunit 3A
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
TTC37 tetratricopeptide repeat domain 37
TUBA1A tubulin, alpha 1a
TUBB tubulin, beta class I
TUBB4B tubulin, beta 4B class IVb
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBE2I ubiquitin-conjugating enzyme E2I
UBE2O ubiquitin-conjugating enzyme E2O
UBR4 ubiquitin protein ligase E3 component n-recognin 4
UBR5 ubiquitin protein ligase E3 component n-recognin 5
USP11 ubiquitin specific peptidase 11
USP34 ubiquitin specific peptidase 34
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
USP9X ubiquitin specific peptidase 9, X-linked
VPRBP Vpr (HIV-1) binding protein
WDR5 WD repeat domain 5
WDR61 WD repeat domain 61
WWP1 WW domain containing E3 ubiquitin protein ligase 1
WWP2 WW domain containing E3 ubiquitin protein ligase 2
XPO1 exportin 1
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YBEY ybeY metallopeptidase (putative)
YBX1 Y box binding protein 1
YBX3 Y box binding protein 3
ZRANB2 zinc finger, RAN-binding domain containing 2