ARRB2 Gene Set

Dataset Hub Proteins Protein-Protein Interactions
Category physical interactions
Type hub protein
Description arrestin, beta 2|Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012] (NCBI Entrez Gene Database, 409)
External Link http://www.ncbi.nlm.nih.gov/gene/409
Similar Terms
Downloads & Tools

Genes

313 interacting proteins for hub protein ARRB2 from the curated Hub Proteins Protein-Protein Interactions dataset.

Symbol Name
ACTB actin, beta
ACTBL2 actin, beta-like 2
ACTC1 actin, alpha, cardiac muscle 1
ACTG2 actin, gamma 2, smooth muscle, enteric
ADRB2 adrenoceptor beta 2, surface
AGTR1 angiotensin II receptor, type 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALYREF Aly/REF export factor
ANXA2 annexin A2
AP1B1 adaptor-related protein complex 1, beta 1 subunit
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP3B1 adaptor-related protein complex 3, beta 1 subunit
AP3B2 adaptor-related protein complex 3, beta 2 subunit
AP3D1 adaptor-related protein complex 3, delta 1 subunit
ARF6 ADP-ribosylation factor 6
ARHGAP17 Rho GTPase activating protein 17
ARHGAP21 Rho GTPase activating protein 21
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARPC5L actin related protein 2/3 complex, subunit 5-like
ARR3 arrestin 3, retinal (X-arrestin)
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
AVPR2 arginine vasopressin receptor 2
BCLAF1 BCL2-associated transcription factor 1
BOLA2 bolA family member 2
BOP1 block of proliferation 1
BSN bassoon presynaptic cytomatrix protein
C11ORF84 chromosome 11 open reading frame 84
C1QBP complement component 1, q subcomponent binding protein
C5AR1 complement component 5a receptor 1
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAMK1G calcium/calmodulin-dependent protein kinase IG
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAPN1 calpain 1, (mu/I) large subunit
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)
CDC42 cell division cycle 42
CDK13 cyclin-dependent kinase 13
CDK3 cyclin-dependent kinase 3
CDK4 cyclin-dependent kinase 4
CDK7 cyclin-dependent kinase 7
CENPF centromere protein F, 350/400kDa
CFL1 cofilin 1 (non-muscle)
CHRM2 cholinergic receptor, muscarinic 2
CHUK conserved helix-loop-helix ubiquitous kinase
CLIC1 chloride intracellular channel 1
CLNS1A chloride channel, nucleotide-sensitive, 1A
CLTA clathrin, light chain A
CLTB clathrin, light chain B
CLTC clathrin, heavy chain (Hc)
COPRS coordinator of PRMT5, differentiation stimulator
CPNE1 copine I
CSN2 casein beta
CSNK1A1L casein kinase 1, alpha 1-like
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2A2 casein kinase 2, alpha prime polypeptide
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CTPS1 CTP synthase 1
CTTN cortactin
CUL5 cullin 5
CXCR4 chemokine (C-X-C motif) receptor 4
CYTH2 cytohesin 2
DBN1 drebrin 1
DCD dermcidin
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DGKE diacylglycerol kinase, epsilon 64kDa
DGKZ diacylglycerol kinase, zeta
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15
DKC1 dyskeratosis congenita 1, dyskerin
DUSP16 dual specificity phosphatase 16
DVL2 dishevelled segment polarity protein 2
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EEF2 eukaryotic translation elongation factor 2
EFTUD2 elongation factor Tu GTP binding domain containing 2
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
EIF4B eukaryotic translation initiation factor 4B
ENG endoglin
EPB41L3 erythrocyte membrane protein band 4.1-like 3
ERH enhancer of rudimentary homolog (Drosophila)
FASN fatty acid synthase
FBL fibrillarin
FFAR4 free fatty acid receptor 4
FLNA filamin A, alpha
FZD4 frizzled class receptor 4
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GSK3B glycogen synthase kinase 3 beta
GSN gelsolin
H1FX H1 histone family, member X
H2AFX H2A histone family, member X
HDAC2 histone deacetylase 2
HDGFRP2 hepatoma-derived growth factor-related protein 2
HIPK3 homeodomain interacting protein kinase 3
HIST1H1A histone cluster 1, H1a
HIST1H1C histone cluster 1, H1c
HIST1H2BO histone cluster 1, H2bo
HIST2H2AB histone cluster 2, H2ab
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPF heterogeneous nuclear ribonucleoprotein F
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H')
HNRNPK heterogeneous nuclear ribonucleoprotein K
HNRNPM heterogeneous nuclear ribonucleoprotein M
HNRNPR heterogeneous nuclear ribonucleoprotein R
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA1A heat shock 70kDa protein 1A
HSPA1L heat shock 70kDa protein 1-like
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HTATSF1 HIV-1 Tat specific factor 1
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
ILF3 interleukin enhancer binding factor 3, 90kDa
ITCH itchy E3 ubiquitin protein ligase
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KPNA3 karyopherin alpha 3 (importin alpha 4)
KPNA4 karyopherin alpha 4 (importin alpha 3)
KPNB1 karyopherin (importin) beta 1
LBR lamin B receptor
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
LHCGR luteinizing hormone/choriogonadotropin receptor
LIMA1 LIM domain and actin binding 1
LRP11 low density lipoprotein receptor-related protein 11
MAP1B microtubule-associated protein 1B
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K4 mitogen-activated protein kinase kinase 4
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK10 mitogen-activated protein kinase 10
MAPK3 mitogen-activated protein kinase 3
MAPK9 mitogen-activated protein kinase 9
MCM3 minichromosome maintenance complex component 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED8 mediator complex subunit 8
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MOB1A MOB kinase activator 1A
MRPL43 mitochondrial ribosomal protein L43
MRPL44 mitochondrial ribosomal protein L44
MYH10 myosin, heavy chain 10, non-muscle
MYH9 myosin, heavy chain 9, non-muscle
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
MYO1C myosin IC
MYOCD myocardin
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit
NAP1L1 nucleosome assembly protein 1-like 1
NCL nucleolin
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NKTR natural killer cell triggering receptor
NOLC1 nucleolar and coiled-body phosphoprotein 1
NONO non-POU domain containing, octamer-binding
NOP10 NOP10 ribonucleoprotein
NOP56 NOP56 ribonucleoprotein
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NSUN2 NOP2/Sun RNA methyltransferase family, member 2
NTS neurotensin
NTSR1 neurotensin receptor 1 (high affinity)
OPRD1 opioid receptor, delta 1
OXTR oxytocin receptor
P4HB prolyl 4-hydroxylase, beta polypeptide
PABPC1 poly(A) binding protein, cytoplasmic 1
PABPC3 poly(A) binding protein, cytoplasmic 3
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form)
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7
PDE4D phosphodiesterase 4D, cAMP-specific
PES1 pescadillo ribosomal biogenesis factor 1
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PHKA2 phosphorylase kinase, alpha 2 (liver)
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PKM pyruvate kinase, muscle
POLR1A polymerase (RNA) I polypeptide A, 194kDa
POLR1B polymerase (RNA) I polypeptide B, 128kDa
POLR1C polymerase (RNA) I polypeptide C, 30kDa
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
POTEKP POTE ankyrin domain family, member K, pseudogene
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRMT1 protein arginine methyltransferase 1
PRMT5 protein arginine methyltransferase 5
PRPF4B pre-mRNA processing factor 4B
PTAFR platelet-activating factor receptor
PTBP1 polypyrimidine tract binding protein 1
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB5C RAB5C, member RAS oncogene family
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RALGDS ral guanine nucleotide dissociation stimulator
RANGAP1 Ran GTPase activating protein 1
RBM10 RNA binding motif protein 10
RPA1 replication protein A1, 70kDa
RPL11 ribosomal protein L11
RPL12 ribosomal protein L12
RPL14 ribosomal protein L14
RPL15 ribosomal protein L15
RPL18 ribosomal protein L18
RPL19 ribosomal protein L19
RPL21 ribosomal protein L21
RPL22 ribosomal protein L22
RPL26 ribosomal protein L26
RPL28 ribosomal protein L28
RPL3 ribosomal protein L3
RPL30 ribosomal protein L30
RPL31 ribosomal protein L31
RPL35 ribosomal protein L35
RPL35A ribosomal protein L35a
RPL36 ribosomal protein L36
RPL4 ribosomal protein L4
RPL6 ribosomal protein L6
RPL7 ribosomal protein L7
RPL7A ribosomal protein L7a
RPL7L1 ribosomal protein L7-like 1
RPLP0 ribosomal protein, large, P0
RPLP1 ribosomal protein, large, P1
RPLP2 ribosomal protein, large, P2
RPN2 ribophorin II
RPS13 ribosomal protein S13
RPS17 ribosomal protein S17
RPS19 ribosomal protein S19
RPS27A ribosomal protein S27a
RPS3 ribosomal protein S3
RPS3A ribosomal protein S3A
RPS4X ribosomal protein S4, X-linked
RPS6 ribosomal protein S6
RPS7 ribosomal protein S7
RPS8 ribosomal protein S8
S100A9 S100 calcium binding protein A9
SAG S-antigen; retina and pineal gland (arrestin)
SCYL2 SCY1-like 2 (S. cerevisiae)
SDC3 syndecan 3
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SERBP1 SERPINE1 mRNA binding protein 1
SF3B1 splicing factor 3b, subunit 1, 155kDa
SF3B2 splicing factor 3b, subunit 2, 145kDa
SF3B3 splicing factor 3b, subunit 3, 130kDa
SFPQ splicing factor proline/glutamine-rich
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
SPIN1 spindlin 1
SPIN3 spindlin family, member 3
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTBN1 spectrin, beta, non-erythrocytic 1
SRPK2 SRSF protein kinase 2
SRRM2 serine/arginine repetitive matrix 2
STAT1 signal transducer and activator of transcription 1, 91kDa
STC2 stanniocalcin 2
STK38 serine/threonine kinase 38
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TCOF1 Treacher Collins-Franceschetti syndrome 1
TGFBR3 transforming growth factor, beta receptor III
THRAP3 thyroid hormone receptor associated protein 3
TMOD3 tropomodulin 3 (ubiquitous)
TMPO thymopoietin
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRH thyrotropin-releasing hormone
TRIM28 tripartite motif containing 28
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TUBA1A tubulin, alpha 1a
TUBA1C tubulin, alpha 1c
TUBA3C tubulin, alpha 3c
TUBA4A tubulin, alpha 4a
TUBA8 tubulin, alpha 8
TUBB2A tubulin, beta 2A class IIa
TUBB3 tubulin, beta 3 class III
TUBB4A tubulin, beta 4A class IVa
TUBB4B tubulin, beta 4B class IVb
TWISTNB TWIST neighbor
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBR5 ubiquitin protein ligase E3 component n-recognin 5
VCP valosin containing protein
VIM vimentin
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae)
WDR26 WD repeat domain 26
WDR77 WD repeat domain 77
WEE1 WEE1 G2 checkpoint kinase
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YBX1 Y box binding protein 1
YBX3 Y box binding protein 3
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
ZRANB2 zinc finger, RAN-binding domain containing 2