AS601245 Gene Set

Dataset LINCS KinomeScan Kinase Inhibitor Targets
Category physical interactions
Type small molecule
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Genes

22 kinases inhibited by the AS601245 small molecule from the KinomeScan Kinase Inhibitor Targets dataset.

Symbol Name Standardized Value
GSK3B glycogen synthase kinase 3 beta 1.35325
HIPK3 homeodomain interacting protein kinase 3 1.34449
CSNK2A1 casein kinase 2, alpha 1 polypeptide 1.33582
MKNK2 MAP kinase interacting serine/threonine kinase 2 1.32726
GSK3A glycogen synthase kinase 3 alpha 1.31878
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 1.3104
CSNK2A2 casein kinase 2, alpha prime polypeptide 1.28583
HIPK1 homeodomain interacting protein kinase 1 1.26991
HIPK2 homeodomain interacting protein kinase 2 1.25436
PIM3 Pim-3 proto-oncogene, serine/threonine kinase 1.18873
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites 1.18186
RIOK2 RIO kinase 2 1.18186
EPHB6 EPH receptor B6 1.12988
CLK2 CDC-like kinase 2 1.09992
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 1.06105
GAK cyclin G associated kinase 1.05057
ANKK1 ankyrin repeat and kinase domain containing 1 1.00208
IRAK1 interleukin-1 receptor-associated kinase 1 0.975893
RIPK4 receptor-interacting serine-threonine kinase 4 0.908676
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma 0.883492
AAK1 AP2 associated kinase 1 0.850157
BMP2K BMP2 inducible kinase 0.850157