ASAP1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description ArfGAP with SH3 domain, ankyrin repeat and PH domain 1|This gene encodes an ADP-ribosylation factor (ARF) GTPase-activating protein. The GTPase-activating activity is stimulated by phosphatidylinositol 4,5-biphosphate (PIP2), and is greater towards ARF1 and ARF5, and lesser for ARF6. This gene maybe involved in regulation of membrane trafficking and cytoskeleton remodeling. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] (NCBI Entrez Gene Database, 50807)
External Link http://www.ncbi.nlm.nih.gov/gene/50807
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192 interacting proteins for ASAP1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
AGER advanced glycosylation end product-specific receptor
APC adenomatous polyposis coli
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARF1 ADP-ribosylation factor 1
ARF6 ADP-ribosylation factor 6
ARHGAP12 Rho GTPase activating protein 12
ARHGAP20 Rho GTPase activating protein 20
ARL1 ADP-ribosylation factor-like 1
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
BCR breakpoint cluster region
BMI1 BMI1 proto-oncogene, polycomb ring finger
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
BTK Bruton agammaglobulinemia tyrosine kinase
C11ORF84 chromosome 11 open reading frame 84
C1ORF27 chromosome 1 open reading frame 27
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CBX4 chromobox homolog 4
CCDC158 coiled-coil domain containing 158
CD2AP CD2-associated protein
CENPF centromere protein F, 350/400kDa
CHD7 chromodomain helicase DNA binding protein 7
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CLTA clathrin, light chain A
CLTB clathrin, light chain B
CNOT1 CCR4-NOT transcription complex, subunit 1
COPA coatomer protein complex, subunit alpha
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CSK c-src tyrosine kinase
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2A2 casein kinase 2, alpha prime polypeptide
CSNK2B casein kinase 2, beta polypeptide
CSRP1 cysteine and glycine-rich protein 1
CTTN cortactin
DARS aspartyl-tRNA synthetase
DIAPH1 diaphanous-related formin 1
DLG1 discs, large homolog 1 (Drosophila)
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DNM1 dynamin 1
DNM2 dynamin 2
DNM3 dynamin 3
DOCK4 dedicator of cytokinesis 4
DOCK5 dedicator of cytokinesis 5
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
EGFR epidermal growth factor receptor
ELAVL1 ELAV like RNA binding protein 1
ELMO2 engulfment and cell motility 2
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
ERCC6 excision repair cross-complementation group 6
ERRFI1 ERBB receptor feedback inhibitor 1
FAM175B family with sequence similarity 175, member B
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
FCHSD1 FCH and double SH3 domains 1
FER fer (fps/fes related) tyrosine kinase
FGD6 FYVE, RhoGEF and PH domain containing 6
FRS2 fibroblast growth factor receptor substrate 2
FUS FUS RNA binding protein
FYB FYN binding protein
FYN FYN proto-oncogene, Src family tyrosine kinase
GAB1 GRB2-associated binding protein 1
GAB2 GRB2-associated binding protein 2
GAREM GRB2 associated, regulator of MAPK1
GAREML GRB2 associated, regulator of MAPK1-like
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GRAP2 GRB2-related adaptor protein 2
GRB2 growth factor receptor-bound protein 2
HACD3 3-hydroxyacyl-CoA dehydratase 3
HCK HCK proto-oncogene, Src family tyrosine kinase
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HIST1H1A histone cluster 1, H1a
HSPG2 heparan sulfate proteoglycan 2
HUNK hormonally up-regulated Neu-associated kinase
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
INPPL1 inositol polyphosphate phosphatase-like 1
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
IRS4 insulin receptor substrate 4
ITSN1 intersectin 1 (SH3 domain protein)
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIRREL kin of IRRE like (Drosophila)
KRT33A keratin 33A, type I
KRT36 keratin 36, type I
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LRRK1 leucine-rich repeat kinase 1
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5
MDM1 Mdm1 nuclear protein homolog (mouse)
MKI67 marker of proliferation Ki-67
MOV10 Mov10 RISC complex RNA helicase
MYCBP MYC binding protein
NCK1 NCK adaptor protein 1
NCKAP1 NCK-associated protein 1
NCKIPSD NCK interacting protein with SH3 domain
NISCH nischarin
NPHP1 nephronophthisis 1 (juvenile)
OPTN optineurin
PACSIN1 protein kinase C and casein kinase substrate in neurons 1
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PCGF2 polycomb group ring finger 2
PCGF6 polycomb group ring finger 6
PHC1 polyhomeotic homolog 1 (Drosophila)
PHC2 polyhomeotic homolog 2 (Drosophila)
PHC3 polyhomeotic homolog 3 (Drosophila)
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLCG1 phospholipase C, gamma 1
PLD1 phospholipase D1, phosphatidylcholine-specific
PLD2 phospholipase D2
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP5C protein phosphatase 5, catalytic subunit
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
PTPRA protein tyrosine phosphatase, receptor type, A
PTPRJ protein tyrosine phosphatase, receptor type, J
PXN paxillin
RADIL Ras association and DIL domains
RBBP6 retinoblastoma binding protein 6
REPS2 RALBP1 associated Eps domain containing 2
RING1 ring finger protein 1
RNF17 ring finger protein 17
RNF2 ring finger protein 2
RRAGA Ras-related GTP binding A
RUVBL2 RuvB-like AAA ATPase 2
SFN stratifin
SH2D5 SH2 domain containing 5
SH3GL2 SH3-domain GRB2-like 2
SH3KBP1 SH3-domain kinase binding protein 1
SH3PXD2A SH3 and PX domains 2A
SH3PXD2B SH3 and PX domains 2B
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIRPA signal-regulatory protein alpha
SKAP2 src kinase associated phosphoprotein 2
SLAIN2 SLAIN motif family, member 2
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
SMC3 structural maintenance of chromosomes 3
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNX18 sorting nexin 18
SNX9 sorting nexin 9
SOS1 son of sevenless homolog 1 (Drosophila)
SOS2 son of sevenless homolog 2 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STAMBP STAM binding protein
STAMBPL1 STAM binding protein-like 1
SYNJ1 synaptojanin 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TEC tec protein tyrosine kinase
TFG TRK-fused gene
TRIP10 thyroid hormone receptor interactor 10
TSG101 tumor susceptibility 101
TTYH2 tweety family member 2
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBASH3B ubiquitin associated and SH3 domain containing B
UBC ubiquitin C
UBR4 ubiquitin protein ligase E3 component n-recognin 4
VAV3 vav 3 guanine nucleotide exchange factor
WASL Wiskott-Aldrich syndrome-like
WDHD1 WD repeat and HMG-box DNA binding protein 1
WDR44 WD repeat domain 44
WDR6 WD repeat domain 6
WDR77 WD repeat domain 77
WIPF1 WAS/WASL interacting protein family, member 1
WIPF2 WAS/WASL interacting protein family, member 2
WIPF3 WAS/WASL interacting protein family, member 3
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZNF546 zinc finger protein 546