ASAP3 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description ArfGAP with SH3 domain, ankyrin repeat and PH domain 3|This gene encodes a member of a subfamily of ADP-ribosylation factor(Arf) GTPase-activating proteins that contain additional ankyrin repeat and pleckstrin homology domains. The Arf GAP domain of this protein catalyzes the hydrolysis of GTP bound to Arf proteins. The encoded protein promotes cell differentiation and migration and has been implicated in cancer cell invasion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009] (NCBI Entrez Gene Database, 55616)
External Link http://www.ncbi.nlm.nih.gov/gene/55616
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Genes

27 interacting proteins for ASAP3 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
AGO1 argonaute RISC catalytic component 1
AGO2 argonaute RISC catalytic component 2
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP2M1 adaptor-related protein complex 2, mu 1 subunit
ARF6 ADP-ribosylation factor 6
CASS4 Cas scaffolding protein family member 4
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CRK v-crk avian sarcoma virus CT10 oncogene homolog
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
EDC4 enhancer of mRNA decapping 4
EPS15 epidermal growth factor receptor pathway substrate 15
GRB2 growth factor receptor-bound protein 2
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
INPPL1 inositol polyphosphate phosphatase-like 1
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SOS1 son of sevenless homolog 1 (Drosophila)
SOS2 son of sevenless homolog 2 (Drosophila)
TTBK2 tau tubulin kinase 2
UBASH3A ubiquitin associated and SH3 domain containing A
UBASH3B ubiquitin associated and SH3 domain containing B