ASCL2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description achaete-scute family bHLH transcription factor 2|This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 430)
External Link https://ncbi.nlm.nih.gov/gene/430
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Genes

499 genes differentially expressed following the ASCL2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
BAMBI BMP and activin membrane-bound inhibitor 0.0142848
SCGB2A1 secretoglobin, family 2A, member 1 0.0132599
PEG3 paternally expressed 3 0.0126447
THBS1 thrombospondin 1 0.0105517
MFAP3L microfibrillar-associated protein 3-like 0.0102745
TPD52L1 tumor protein D52-like 1 0.0101106
ALCAM activated leukocyte cell adhesion molecule 0.010023
LCN2 lipocalin 2 0.00985102
TXLNA taxilin alpha 0.00963712
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.00895279
CXCL2 chemokine (C-X-C motif) ligand 2 0.00887771
MUC16 mucin 16, cell surface associated 0.00864518
WT1 Wilms tumor 1 0.00864346
EFHD1 EF-hand domain family, member D1 0.00860915
MCTP1 multiple C2 domains, transmembrane 1 0.00855331
CRABP1 cellular retinoic acid binding protein 1 0.00847009
ACTA2 actin, alpha 2, smooth muscle, aorta 0.0084647
RRAGD Ras-related GTP binding D 0.00833399
SCGB1D2 secretoglobin, family 1D, member 2 0.00806322
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.00805973
DCN decorin 0.00803218
ATXN1 ataxin 1 0.00783702
FAM171A1 family with sequence similarity 171, member A1 0.00776329
FSCN1 fascin actin-bundling protein 1 0.00760681
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.00757628
IFI27 interferon, alpha-inducible protein 27 0.00754723
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.00749653
ICA1 islet cell autoantigen 1, 69kDa 0.00746665
QPRT quinolinate phosphoribosyltransferase 0.00737616
GPR137B G protein-coupled receptor 137B 0.00736123
DEFB1 defensin, beta 1 0.00735276
EMX2 empty spiracles homeobox 2 0.00733938
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.00729456
HEPH hephaestin 0.00727629
CCN2 cellular communication network factor 2 0.0072046
CALB1 calbindin 1, 28kDa 0.00719855
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 0.00719498
VNN1 vanin 1 0.00718498
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.00711341
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.007097
NCOA3 nuclear receptor coactivator 3 0.00707038
THBS2 thrombospondin 2 0.00706799
SCGB2A2 secretoglobin, family 2A, member 2 0.00699508
TDO2 tryptophan 2,3-dioxygenase 0.0069776
CD69 CD69 molecule 0.00696612
CCDC6 coiled-coil domain containing 6 0.00692331
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.00691571
SLC39A8 solute carrier family 39 (zinc transporter), member 8 0.00691184
SIRT3 sirtuin 3 0.00690168
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 0.0068799
GSTM3 glutathione S-transferase mu 3 (brain) 0.00685668
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 0.00682354
CHEK2 checkpoint kinase 2 0.00681428
KIAA0355 KIAA0355 0.00681365
TM4SF1 transmembrane 4 L six family member 1 0.00678677
SFRP4 secreted frizzled-related protein 4 0.00678572
DSP desmoplakin 0.00677061
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.00675898
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.00669305
ZBTB10 zinc finger and BTB domain containing 10 0.00668087
HOMER1 homer scaffolding protein 1 0.00667863
IL1R1 interleukin 1 receptor, type I 0.00666295
SULF1 sulfatase 1 0.00662156
KLF10 Kruppel-like factor 10 0.00661177
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.00659907
KRT23 keratin 23, type I 0.00657986
SOX9 SRY (sex determining region Y)-box 9 0.00653677
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.0065329
CLDN10 claudin 10 0.00652729
MAP2K6 mitogen-activated protein kinase kinase 6 0.00645249
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.00644377
MLF1 myeloid leukemia factor 1 0.00643874
RGS4 regulator of G-protein signaling 4 0.00642966
DNASE1L3 deoxyribonuclease I-like 3 0.00640905
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 0.00640237
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.00635573
KLF9 Kruppel-like factor 9 0.00632638
COL6A3 collagen, type VI, alpha 3 0.00631914
TLR4 toll-like receptor 4 0.00631358
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.0062689
WASL Wiskott-Aldrich syndrome-like 0.00621133
SNAI2 snail family zinc finger 2 0.00619196
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 0.0061916
CXCL12 chemokine (C-X-C motif) ligand 12 0.00619127
CLDN3 claudin 3 0.00617795
MAP7 microtubule-associated protein 7 0.00617791
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 0.00617484
FTH1 ferritin, heavy polypeptide 1 0.00617078
HSPH1 heat shock 105kDa/110kDa protein 1 0.00615032
DOCK4 dedicator of cytokinesis 4 0.00613061
RIPOR2 RHO family interacting cell polarization regulator 2 0.00607682
LAPTM4B lysosomal protein transmembrane 4 beta 0.00607466
BGN biglycan 0.00606426
RNF144A ring finger protein 144A 0.00605967
TRPS1 trichorhinophalangeal syndrome I 0.00604722
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.00602459
ABHD2 abhydrolase domain containing 2 0.00596685
WIPI1 WD repeat domain, phosphoinositide interacting 1 0.0059635
CXCL8 chemokine (C-X-C motif) ligand 8 0.00592896
PAEP progestagen-associated endometrial protein 0.00592069
TNNT1 troponin T type 1 (skeletal, slow) 0.00589196
BCL2A1 BCL2-related protein A1 0.00589079
ZEB2 zinc finger E-box binding homeobox 2 0.00586478
SGCE sarcoglycan, epsilon 0.00583918
LY75 lymphocyte antigen 75 0.00582911
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.00582044
GRAMD2B GRAM domain containing 2B 0.00580169
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.00579377
NBR1 neighbor of BRCA1 gene 1 0.00576488
TAC1 tachykinin, precursor 1 0.00576354
RCAN1 regulator of calcineurin 1 0.00576112
WSB2 WD repeat and SOCS box containing 2 0.00575207
INHBA inhibin, beta A 0.00573141
CLIC5 chloride intracellular channel 5 0.00572575
PEG10 paternally expressed 10 0.00571694
IL17RB interleukin 17 receptor B 0.00570516
IFITM1 interferon induced transmembrane protein 1 0.00568654
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.0056815
LIMS1 LIM and senescent cell antigen-like domains 1 0.0056806
CASP7 caspase 7, apoptosis-related cysteine peptidase 0.0056761
KLHL24 kelch-like family member 24 0.00567272
HTRA1 HtrA serine peptidase 1 0.00566622
CLU clusterin 0.00565583
CYBA cytochrome b-245, alpha polypeptide 0.0056174
SYNE1 spectrin repeat containing, nuclear envelope 1 0.0056088
PDE2A phosphodiesterase 2A, cGMP-stimulated 0.00560836
GCH1 GTP cyclohydrolase 1 0.00560588
MMP19 matrix metallopeptidase 19 0.00559673
XIC X chromosome inactivation center 0.00557651
CPA3 carboxypeptidase A3 (mast cell) 0.0055672
MDK midkine (neurite growth-promoting factor 2) 0.00555328
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 0.00555217
EPCAM epithelial cell adhesion molecule 0.00554397
UBE2D1 ubiquitin-conjugating enzyme E2D 1 0.00554089
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 0.00551773
EREG epiregulin 0.00548771
GCA grancalcin, EF-hand calcium binding protein 0.00548062
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.005475
FBLN5 fibulin 5 0.00546127
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.00545159
EDN1 endothelin 1 0.00541546
CXCL13 chemokine (C-X-C motif) ligand 13 0.00540433
PITX3 paired-like homeodomain 3 0.00539034
C1ORF115 chromosome 1 open reading frame 115 0.00538083
FRMD4B FERM domain containing 4B 0.00538027
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.00537751
GNG5 guanine nucleotide binding protein (G protein), gamma 5 0.00537475
FOS FBJ murine osteosarcoma viral oncogene homolog 0.00537017
KCTD12 potassium channel tetramerization domain containing 12 0.00536939
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 0.00536863
SLPI secretory leukocyte peptidase inhibitor 0.00535346
GPR88 G protein-coupled receptor 88 0.00534611
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.00534143
TOB2 transducer of ERBB2, 2 0.00532008
C5AR1 complement component 5a receptor 1 0.00530722
GARS1 glycyl-tRNA synthetase 1 0.0052982
CXCL3 chemokine (C-X-C motif) ligand 3 0.00529424
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.0052916
PRPS2 phosphoribosyl pyrophosphate synthetase 2 0.00527188
NAV3 neuron navigator 3 0.0052677
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.00526137
DACT1 dishevelled-binding antagonist of beta-catenin 1 0.0052607
STC2 stanniocalcin 2 0.00525987
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.00525631
CTSK cathepsin K 0.00524309
ARG1 arginase 1 0.00523576
MYB v-myb avian myeloblastosis viral oncogene homolog 0.00523496
LIMK2 LIM domain kinase 2 0.00522983
DUSP2 dual specificity phosphatase 2 0.00522761
ICAM2 intercellular adhesion molecule 2 0.00516952
VTCN1 V-set domain containing T cell activation inhibitor 1 0.00516943
NME5 NME/NM23 family member 5 0.00515965
EVI2A ecotropic viral integration site 2A 0.00514183
RRAS2 related RAS viral (r-ras) oncogene homolog 2 0.00513941
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.00510737
CLEC7A C-type lectin domain family 7, member A 0.00510664
IRX5 iroquois homeobox 5 0.00510529
ASRGL1 asparaginase like 1 0.00509494
PHACTR1 phosphatase and actin regulator 1 0.0050913
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 0.00507599
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 0.0050616
AMIGO2 adhesion molecule with Ig-like domain 2 0.00506038
MARCKSL1 MARCKS-like 1 0.00505366
ANO3 anoctamin 3 0.00504887
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 0.00503045
CEL carboxyl ester lipase 0.00502759
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 0.00501705
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00499427
SDCBP syndecan binding protein (syntenin) 0.00499276
LRIF1 ligand dependent nuclear receptor interacting factor 1 0.00498381
PCOLCE procollagen C-endopeptidase enhancer 0.00497236
LMCD1 LIM and cysteine-rich domains 1 0.00496285
AEBP1 AE binding protein 1 0.00496251
NCF2 neutrophil cytosolic factor 2 0.00495991
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 0.00493532
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.00491399
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.00489542
JUNB jun B proto-oncogene 0.004892
MARCKS myristoylated alanine-rich protein kinase C substrate 0.00488336
ABHD4 abhydrolase domain containing 4 0.00487604
PLIN2 perilipin 2 0.00487542
ZIC1 Zic family member 1 0.00486632
KLK6 kallikrein-related peptidase 6 0.00484785
QPCT glutaminyl-peptide cyclotransferase 0.00484411
HOXD3 homeobox D3 0.00484272
SGPP1 sphingosine-1-phosphate phosphatase 1 0.00483721
LY96 lymphocyte antigen 96 0.00483505
ELF5 E74-like factor 5 (ets domain transcription factor) 0.0048238
ODC1 ornithine decarboxylase 1 0.00482168
TPD52L2 tumor protein D52-like 2 0.00478907
PROX1 prospero homeobox 1 0.00478767
ACOX1 acyl-CoA oxidase 1, palmitoyl 0.00478011
CHKB choline kinase beta 0.00477582
NDP Norrie disease (pseudoglioma) 0.00476017
SRPK2 SRSF protein kinase 2 0.00475661
SNX11 sorting nexin 11 0.00473966
LRRC15 leucine rich repeat containing 15 0.0047391
MAP3K8 mitogen-activated protein kinase kinase kinase 8 0.00473043
DAXX death-domain associated protein 0.00470877
SPIN1 spindlin 1 0.00469627
WARS1 tryptophanyl-tRNA synthetase 1 0.00468818
FNBP1L formin binding protein 1-like 0.00468381
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.00468158
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 0.0046764
EVI5 ecotropic viral integration site 5 0.00466482
TSC22D1 TSC22 domain family, member 1 0.0046603
KLK10 kallikrein-related peptidase 10 0.00465233
SELL selectin L 0.00464927
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.00462585
GPR183 G protein-coupled receptor 183 0.0046155
ZNF165 zinc finger protein 165 0.00461124
KRT19 keratin 19, type I 0.00460761
FMO1 flavin containing monooxygenase 1 0.00460276
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.00460181
GSK3B glycogen synthase kinase 3 beta 0.00459701
JADE3 jade family PHD finger 3 0.00459635
TSPYL4 TSPY-like 4 0.0045938
CNOT4 CCR4-NOT transcription complex, subunit 4 0.00459046
DACH1 dachshund family transcription factor 1 0.00459037
CD4 CD4 molecule 0.00458575
THY1 Thy-1 cell surface antigen 0.00458513
ITGAV integrin, alpha V 0.00458173
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.00456584
ISLR immunoglobulin superfamily containing leucine-rich repeat 0.00455575
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.00454475
RGL1 ral guanine nucleotide dissociation stimulator-like 1 0.00454342
ARPP21 cAMP-regulated phosphoprotein, 21kDa 0.00452271
AP1AR adaptor-related protein complex 1 associated regulatory protein 0.00451425
FPR1 formyl peptide receptor 1 0.00451404

decreased expression

Symbol Name Standardized Value
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.0159428
SFRP1 secreted frizzled-related protein 1 -0.0117734
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0107126
KRT13 keratin 13, type I -0.00932346
BMP4 bone morphogenetic protein 4 -0.00913572
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.00883341
CTSE cathepsin E -0.00846326
HOPX HOP homeobox -0.00825454
SOX11 SRY (sex determining region Y)-box 11 -0.00819513
FABP7 fatty acid binding protein 7, brain -0.00819291
CD34 CD34 molecule -0.00819187
PSCA prostate stem cell antigen -0.00812814
SCD5 stearoyl-CoA desaturase 5 -0.00784837
PITX1 paired-like homeodomain 1 -0.00780754
CD320 CD320 molecule -0.00771806
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.00764062
IPO13 importin 13 -0.00748477
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.00731623
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -0.00729216
FOXF1 forkhead box F1 -0.00728376
EDN3 endothelin 3 -0.00721197
COPS7A COP9 signalosome subunit 7A -0.00710206
BEX1 brain expressed, X-linked 1 -0.00709678
FAM13A family with sequence similarity 13, member A -0.00707354
BCHE butyrylcholinesterase -0.00697473
KCNK3 potassium channel, two pore domain subfamily K, member 3 -0.00690104
KDM5D lysine (K)-specific demethylase 5D -0.00686249
C3 complement component 3 -0.00684902
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.00681571
NMU neuromedin U -0.00677449
MET MET proto-oncogene, receptor tyrosine kinase -0.00674534
PPARG peroxisome proliferator-activated receptor gamma -0.00673373
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 -0.0067175
ANXA10 annexin A10 -0.00668768
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00666566
ITGA7 integrin, alpha 7 -0.00664779
CA9 carbonic anhydrase IX -0.00661117
GNAS GNAS complex locus -0.0066038
APOD apolipoprotein D -0.00657042
ERBB3 erb-b2 receptor tyrosine kinase 3 -0.00651715
MAT2A methionine adenosyltransferase II, alpha -0.00649851
NTS neurotensin -0.00649057
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 -0.00648949
FBN2 fibrillin 2 -0.00645033
PGF placental growth factor -0.00638796
ZNF395 zinc finger protein 395 -0.00626999
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -0.00626641
SPRR3 small proline-rich protein 3 -0.00626427
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.00615523
RBPMS RNA binding protein with multiple splicing -0.00613262
LIPF lipase, gastric -0.00612031
CRYBG1 crystallin beta-gamma domain containing 1 -0.00606223
LMO3 LIM domain only 3 (rhombotin-like 2) -0.0060144
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.00599045
CA2 carbonic anhydrase II -0.00595724
DES desmin -0.00592847
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -0.00592358
HK2 hexokinase 2 -0.00587518
LY6D lymphocyte antigen 6 complex, locus D -0.00581127
EZR ezrin -0.00573725
SPARCL1 SPARC-like 1 (hevin) -0.00571265
CFD complement factor D (adipsin) -0.00569643
RNH1 ribonuclease/angiogenin inhibitor 1 -0.00569354
SH3BGRL SH3 domain binding glutamate-rich protein like -0.00566575
SLC39A14 solute carrier family 39 (zinc transporter), member 14 -0.00562836
ELP1 elongator acetyltransferase complex subunit 1 -0.0056079
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00560317
VLDLR very low density lipoprotein receptor -0.00559792
CAPG capping protein (actin filament), gelsolin-like -0.00559433
TMEM255A transmembrane protein 255A -0.0055776
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00557698
ACADVL acyl-CoA dehydrogenase, very long chain -0.00552261
NPEPL1 aminopeptidase-like 1 -0.00551437
KANK1 KN motif and ankyrin repeat domains 1 -0.0054824
ENO2 enolase 2 (gamma, neuronal) -0.00543917
ADAMTSL3 ADAMTS-like 3 -0.00539846
ITGA6 integrin, alpha 6 -0.00539446
MAST4 microtubule associated serine/threonine kinase family member 4 -0.00538415
P4HB prolyl 4-hydroxylase, beta polypeptide -0.00535969
HHEX hematopoietically expressed homeobox -0.00535847
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.00533345
SPRED2 sprouty-related, EVH1 domain containing 2 -0.00531867
CXADR coxsackie virus and adenovirus receptor -0.00530303
KIF20A kinesin family member 20A -0.00529043
ASPH aspartate beta-hydroxylase -0.00527538
GSTP1 glutathione S-transferase pi 1 -0.00523329
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -0.00520594
FOXE1 forkhead box E1 -0.00519689
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.0051959
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.00513898
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced -0.00512891
DUOX2 dual oxidase 2 -0.00510242
S100A8 S100 calcium binding protein A8 -0.00509873
EFHD2 EF-hand domain family, member D2 -0.00509237
RETREG1 reticulophagy regulator 1 -0.00509212
CLDN1 claudin 1 -0.0050455
EDRF1 erythroid differentiation regulatory factor 1 -0.00502621
NPTX2 neuronal pentraxin II -0.00501516
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -0.00501292
OLFM4 olfactomedin 4 -0.0049851
TKTL1 transketolase-like 1 -0.00496337
PAN2 PAN2 poly(A) specific ribonuclease subunit -0.00496211
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 -0.00495433
SPINK5 serine peptidase inhibitor, Kazal type 5 -0.00494609
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00494111
FAM162A family with sequence similarity 162, member A -0.00492625
FABP5 fatty acid binding protein 5 (psoriasis-associated) -0.0049225
TRIM9 tripartite motif containing 9 -0.00492243
SDC2 syndecan 2 -0.0049173
EPS8 epidermal growth factor receptor pathway substrate 8 -0.00490147
MT1M metallothionein 1M -0.00488384
PRDX2 peroxiredoxin 2 -0.00486544
RNF24 ring finger protein 24 -0.00484634
IRAK1 interleukin-1 receptor-associated kinase 1 -0.00484294
MPZL2 myelin protein zero-like 2 -0.0048413
ANGPTL4 angiopoietin-like 4 -0.00483087
SRSF5 serine/arginine-rich splicing factor 5 -0.00482896
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 -0.00482389
FASN fatty acid synthase -0.00482147
FXYD6 FXYD domain containing ion transport regulator 6 -0.00481974
RXRA retinoid X receptor, alpha -0.00481009
RERE arginine-glutamic acid dipeptide (RE) repeats -0.00479773
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 -0.00479488
GPC4 glypican 4 -0.00479042
TNC tenascin C -0.00478633
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.0047784
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.0047496
SETBP1 SET binding protein 1 -0.00473844
S100A4 S100 calcium binding protein A4 -0.00473814
PBK PDZ binding kinase -0.00473635
RGS5 regulator of G-protein signaling 5 -0.0047292
PLAT plasminogen activator, tissue -0.00472831
RHOA ras homolog family member A -0.00471532
IGSF1 immunoglobulin superfamily, member 1 -0.00470883
IFT57 intraflagellar transport 57 -0.00470779
MEOX2 mesenchyme homeobox 2 -0.00469313
MALL mal, T-cell differentiation protein-like -0.00467632
EGR1 early growth response 1 -0.00466528
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.00465969
OPHN1 oligophrenin 1 -0.00463045
LGALS1 lectin, galactoside-binding, soluble, 1 -0.00462663
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00461221
LAT2 linker for activation of T cells family, member 2 -0.0046011
ALOX12 arachidonate 12-lipoxygenase -0.00459376
PGC progastricsin (pepsinogen C) -0.00459005
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.00458437
SSR4 signal sequence receptor, delta -0.00457583
VIM vimentin -0.00456179
TMPRSS11E transmembrane protease, serine 11E -0.00456037
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -0.00455881
HK1 hexokinase 1 -0.00455427
FABP6 fatty acid binding protein 6, ileal -0.00455025
BCAP31 B-cell receptor-associated protein 31 -0.00454857
CYB5A cytochrome b5 type A (microsomal) -0.00454567
GPC3 glypican 3 -0.00454504
FRS2 fibroblast growth factor receptor substrate 2 -0.00453708
SEPTIN10 septin 10 -0.00453398
MATN2 matrilin 2 -0.0045321
NME4 NME/NM23 nucleoside diphosphate kinase 4 -0.00450625
PADI3 peptidyl arginine deiminase, type III -0.00449847
STC1 stanniocalcin 1 -0.00449832
CNPY2 canopy FGF signaling regulator 2 -0.00446365
TG thyroglobulin -0.00443526
PTCH1 patched 1 -0.00443157
APLP2 amyloid beta (A4) precursor-like protein 2 -0.00442868
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 -0.00442811
STX1A syntaxin 1A (brain) -0.00442295
L1CAM L1 cell adhesion molecule -0.00441896
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A -0.00441438
ELOVL2 ELOVL fatty acid elongase 2 -0.00441034
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -0.00440564
SPRR1B small proline-rich protein 1B -0.00439776
P3H2 prolyl 3-hydroxylase 2 -0.00439758
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide -0.0043952
NMB neuromedin B -0.00439487
RAMP3 receptor (G protein-coupled) activity modifying protein 3 -0.00438005
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 -0.00437303
KRT6A keratin 6A, type II -0.00435023
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.00434894
EPHX3 epoxide hydrolase 3 -0.00434472
KIF23 kinesin family member 23 -0.00431429
STK39 serine threonine kinase 39 -0.00429281
SPTBN1 spectrin, beta, non-erythrocytic 1 -0.00428694
GYPC glycophorin C (Gerbich blood group) -0.00428632
HOXA5 homeobox A5 -0.00427547
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.00426281
ACTC1 actin, alpha, cardiac muscle 1 -0.00423917
PRR15L proline rich 15-like -0.00423192
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.0042164
WASHC4 WASH complex subunit 4 -0.0042133
SNX5 sorting nexin 5 -0.00421127
MTMR11 myotubularin related protein 11 -0.00420508
CST4 cystatin S -0.00420303
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -0.00420118
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -0.00418449
TMEM51 transmembrane protein 51 -0.00417371
ACTG2 actin, gamma 2, smooth muscle, enteric -0.00416467
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 -0.00415609
TLK2 tousled-like kinase 2 -0.00415222
DGKD diacylglycerol kinase, delta 130kDa -0.00415121
CTSH cathepsin H -0.004148
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 -0.00414533
PDZK1 PDZ domain containing 1 -0.00413061
NOL6 nucleolar protein 6 (RNA-associated) -0.00412832
ICMT isoprenylcysteine carboxyl methyltransferase -0.0041282
SFTPD surfactant protein D -0.00412045
RPL10 ribosomal protein L10 -0.0041193
TFF2 trefoil factor 2 -0.00411443
SOD3 superoxide dismutase 3, extracellular -0.00410068
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -0.00409831
GKN1 gastrokine 1 -0.0040913
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) -0.0040813
PTPRE protein tyrosine phosphatase, receptor type, E -0.00407923
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.00407698
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial -0.00407375
FAM189A2 family with sequence similarity 189, member A2 -0.00407285
PTGER3 prostaglandin E receptor 3 (subtype EP3) -0.00406709
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 -0.00406622
C2ORF68 chromosome 2 open reading frame 68 -0.00406317
FSTL1 follistatin-like 1 -0.00406234
ZNF219 zinc finger protein 219 -0.00405539
THPO thrombopoietin -0.00405195
GUSB glucuronidase, beta -0.00404506
CTSL cathepsin L -0.00403731
MZT2A mitotic spindle organizing protein 2A -0.0040354
MAPK10 mitogen-activated protein kinase 10 -0.00402891
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00401701
PRNP prion protein -0.00401536
ECE1 endothelin converting enzyme 1 -0.00399584
GPX1 glutathione peroxidase 1 -0.00398271
REG3A regenerating islet-derived 3 alpha -0.00398006
ADCY6 adenylate cyclase 6 -0.00397687
RFX5 regulatory factor X, 5 (influences HLA class II expression) -0.00397177
TLE5 TLE family member 5, transcriptional modulator -0.00397177
CORO1A coronin, actin binding protein, 1A -0.00397108
FAAH fatty acid amide hydrolase -0.00397011
TREM2 triggering receptor expressed on myeloid cells 2 -0.00396977
REG1A regenerating islet-derived 1 alpha -0.00395545
GPRC5C G protein-coupled receptor, class C, group 5, member C -0.00395335
ETFB electron-transfer-flavoprotein, beta polypeptide -0.0039508
DHDDS dehydrodolichyl diphosphate synthase -0.00394131
APMAP adipocyte plasma membrane associated protein -0.00394097
SC5D sterol-C5-desaturase -0.00393885
FLRT3 fibronectin leucine rich transmembrane protein 3 -0.00392365
SLC35G2 solute carrier family 35, member G2 -0.00392273
NCK1 NCK adaptor protein 1 -0.00392208
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.00392205
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -0.00391072
CYTH4 cytohesin 4 -0.0039054
TM4SF4 transmembrane 4 L six family member 4 -0.00390161