ASGR2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description asialoglycoprotein receptor 2|This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011] (NCBI Entrez Gene Database, 433)
External Link https://ncbi.nlm.nih.gov/gene/433
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Genes

500 genes differentially expressed following the ASGR2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.0165043
BMP4 bone morphogenetic protein 4 0.0154754
FGFR3 fibroblast growth factor receptor 3 0.014809
RGCC regulator of cell cycle 0.0136178
LCN2 lipocalin 2 0.0109251
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.0109098
KLK10 kallikrein-related peptidase 10 0.010789
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.0104703
AREG amphiregulin 0.0103239
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.0100688
VNN1 vanin 1 0.0100297
CD9 CD9 molecule 0.00952409
KLK6 kallikrein-related peptidase 6 0.00926941
AOC1 amine oxidase, copper containing 1 0.0090531
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.00877306
CRABP2 cellular retinoic acid binding protein 2 0.0087221
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.00867386
ADD3 adducin 3 (gamma) 0.00855353
MDK midkine (neurite growth-promoting factor 2) 0.0083027
PDE2A phosphodiesterase 2A, cGMP-stimulated 0.00825457
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.00823019
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00818801
RAB25 RAB25, member RAS oncogene family 0.00814557
MYB v-myb avian myeloblastosis viral oncogene homolog 0.00812351
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.00806565
PODXL podocalyxin-like 0.00803768
THBS1 thrombospondin 1 0.00796478
MMP10 matrix metallopeptidase 10 0.00793443
KRT19 keratin 19, type I 0.0078068
ALCAM activated leukocyte cell adhesion molecule 0.00776033
EVI2A ecotropic viral integration site 2A 0.00775138
NMU neuromedin U 0.00767356
DDAH2 dimethylarginine dimethylaminohydrolase 2 0.00762613
EREG epiregulin 0.00755803
KLK8 kallikrein-related peptidase 8 0.00755456
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.00754896
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.0075373
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 0.00752839
ENC1 ectodermal-neural cortex 1 (with BTB domain) 0.00749185
DLK1 delta-like 1 homolog (Drosophila) 0.00748564
EMX2 empty spiracles homeobox 2 0.00743699
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.00736167
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.00734633
BGN biglycan 0.00731386
VWF von Willebrand factor 0.00728709
ACKR3 atypical chemokine receptor 3 0.00725604
GPM6A glycoprotein M6A 0.00725212
ARG1 arginase 1 0.00723052
KRT5 keratin 5, type II 0.0071978
DOK5 docking protein 5 0.00719303
MMRN1 multimerin 1 0.00718929
TMEM14A transmembrane protein 14A 0.00716506
ZNF423 zinc finger protein 423 0.00711869
DACH1 dachshund family transcription factor 1 0.00711614
S100A2 S100 calcium binding protein A2 0.00708119
MUC16 mucin 16, cell surface associated 0.00707822
SCGB2A1 secretoglobin, family 2A, member 1 0.00706812
EFNB2 ephrin-B2 0.00704449
CHEK2 checkpoint kinase 2 0.00700435
BAMBI BMP and activin membrane-bound inhibitor 0.00697342
LOXL1 lysyl oxidase-like 1 0.00693742
RPS5 ribosomal protein S5 0.00691639
ALDOB aldolase B, fructose-bisphosphate 0.00685039
PITX3 paired-like homeodomain 3 0.00684718
EDN1 endothelin 1 0.00682716
AUTS2 autism susceptibility candidate 2 0.00681538
AK4 adenylate kinase 4 0.00679907
S100P S100 calcium binding protein P 0.00678646
DCXR dicarbonyl/L-xylulose reductase 0.00677906
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.00676358
CHEK1 checkpoint kinase 1 0.0067585
SST somatostatin 0.00672343
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.00671323
AQP3 aquaporin 3 (Gill blood group) 0.00668286
SELENBP1 selenium binding protein 1 0.00665581
PLPP3 phospholipid phosphatase 3 0.00662401
SDC1 syndecan 1 0.00660279
CLDN10 claudin 10 0.00658472
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.00658403
COMP cartilage oligomeric matrix protein 0.00656691
MAP2K6 mitogen-activated protein kinase kinase 6 0.00652495
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.00651876
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.006507
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00650383
TMEM204 transmembrane protein 204 0.00646912
ELN elastin 0.00646761
S100A9 S100 calcium binding protein A9 0.00645322
CEMIP cell migration inducing protein, hyaluronan binding 0.00645143
ZW10 zw10 kinetochore protein 0.00638709
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 0.00637177
HTRA1 HtrA serine peptidase 1 0.00635954
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.00634022
KLK11 kallikrein-related peptidase 11 0.00633363
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.00632459
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00630847
TYRP1 tyrosinase-related protein 1 0.00627136
PCOLCE2 procollagen C-endopeptidase enhancer 2 0.00624843
FERMT1 fermitin family member 1 0.00623828
AQP1 aquaporin 1 (Colton blood group) 0.0062248
IL17RB interleukin 17 receptor B 0.006213
TACSTD2 tumor-associated calcium signal transducer 2 0.00619473
TCF21 transcription factor 21 0.00614354
AURKB aurora kinase B 0.00612918
ICA1 islet cell autoantigen 1, 69kDa 0.00611678
MECOM MDS1 and EVI1 complex locus 0.0061135
IQCE IQ motif containing E 0.00611111
FRMD4B FERM domain containing 4B 0.00610847
GCA grancalcin, EF-hand calcium binding protein 0.00610135
CALB1 calbindin 1, 28kDa 0.00607586
MLF1 myeloid leukemia factor 1 0.00607306
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.00605935
IL10RB interleukin 10 receptor, beta 0.00601178
MFAP2 microfibrillar-associated protein 2 0.00600816
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.00599599
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00597689
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.00596127
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 0.00595945
ZNF652 zinc finger protein 652 0.00591113
ATXN1 ataxin 1 0.00591058
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00590912
TNNT1 troponin T type 1 (skeletal, slow) 0.00588815
KCTD12 potassium channel tetramerization domain containing 12 0.00587736
SOSTDC1 sclerostin domain containing 1 0.00585015
IFT27 intraflagellar transport 27 0.0058343
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 0.0058063
CFAP298 cilia and flagella associated protein 298 0.00580032
AMH anti-Mullerian hormone 0.00578162
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00576699
CLIC5 chloride intracellular channel 5 0.00574829
FGFBP1 fibroblast growth factor binding protein 1 0.00573272
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 0.00570616
SELE selectin E 0.00569745
FGFR4 fibroblast growth factor receptor 4 0.00566248
HIP1 huntingtin interacting protein 1 0.00565784
LGALS4 lectin, galactoside-binding, soluble, 4 0.00565737
EFHD1 EF-hand domain family, member D1 0.0056472
COMMD8 COMM domain containing 8 0.00563784
GAS6 growth arrest-specific 6 0.00562675
KLF10 Kruppel-like factor 10 0.00559007
ANO1 anoctamin 1, calcium activated chloride channel 0.00558831
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.00558109
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.00557598
TOX thymocyte selection-associated high mobility group box 0.00557266
FABP1 fatty acid binding protein 1, liver 0.00556947
FST follistatin 0.00555834
BMX BMX non-receptor tyrosine kinase 0.00555695
RFC2 replication factor C (activator 1) 2, 40kDa 0.00553728
IL15 interleukin 15 0.00553722
CRIP1 cysteine-rich protein 1 (intestinal) 0.00553628
ATP11B ATPase, class VI, type 11B 0.00552745
DEFA5 defensin, alpha 5, Paneth cell-specific 0.00552392
APLP1 amyloid beta (A4) precursor-like protein 1 0.00551545
SPC25 SPC25, NDC80 kinetochore complex component 0.00550553
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.00550009
CSRP2 cysteine and glycine-rich protein 2 0.00549821
FZD10 frizzled class receptor 10 0.00548973
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 0.0054834
KDM5D lysine (K)-specific demethylase 5D 0.00546247
TMEM176A transmembrane protein 176A 0.00545329
SEPP1 selenoprotein P, plasma, 1 0.00545286
ZNF395 zinc finger protein 395 0.00544029
NEBL nebulette 0.00543311
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.00540034
CXCL14 chemokine (C-X-C motif) ligand 14 0.00537951
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.00537466
METRN meteorin, glial cell differentiation regulator 0.00536365
ZNF264 zinc finger protein 264 0.00535618
ITGA8 integrin, alpha 8 0.00534924
DAXX death-domain associated protein 0.00534691
ANXA6 annexin A6 0.00534525
ASRGL1 asparaginase like 1 0.00534495
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 0.0053336
LAGE3 L antigen family, member 3 0.00532615
PAH phenylalanine hydroxylase 0.00532237
H1-0 H1.0 linker histone 0.00531997
PTPRO protein tyrosine phosphatase, receptor type, O 0.00531589
FOXG1 forkhead box G1 0.00530924
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 0.00530778
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 0.00530173
IRF6 interferon regulatory factor 6 0.00528853
F2R coagulation factor II (thrombin) receptor 0.00527962
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.00525185
FAM171A1 family with sequence similarity 171, member A1 0.00524402
FCGBP Fc fragment of IgG binding protein 0.00524296
EIF5A eukaryotic translation initiation factor 5A 0.00523495
MYRF myelin regulatory factor 0.00522649
MAL mal, T-cell differentiation protein 0.00522326
SLC2A4RG SLC2A4 regulator 0.00521614
CD93 CD93 molecule 0.00521364
PEX2 peroxisomal biogenesis factor 2 0.00521324
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 0.00521317
TMEM47 transmembrane protein 47 0.00520731
SLC39A4 solute carrier family 39 (zinc transporter), member 4 0.00519344
PEA15 phosphoprotein enriched in astrocytes 15 0.00518673
CPOX coproporphyrinogen oxidase 0.00518429
CRELD2 cysteine-rich with EGF-like domains 2 0.00517317
IFITM2 interferon induced transmembrane protein 2 0.00517187
CRABP1 cellular retinoic acid binding protein 1 0.00517179
RTN3 reticulon 3 0.00516096
TRIM29 tripartite motif containing 29 0.00515384
MMP19 matrix metallopeptidase 19 0.00515271
ALDH6A1 aldehyde dehydrogenase 6 family, member A1 0.00515067
TPBG trophoblast glycoprotein 0.00514088
LYRM1 LYR motif containing 1 0.00513719
BIK BCL2-interacting killer (apoptosis-inducing) 0.00513614
KRT20 keratin 20, type I 0.00513594
GPR183 G protein-coupled receptor 183 0.00511022
IL20RA interleukin 20 receptor, alpha 0.00510845
DCAF10 DDB1 and CUL4 associated factor 10 0.00510312
RAD51 RAD51 recombinase 0.00509737
DIPK1A divergent protein kinase domain 1A 0.00509547
PLPBP pyridoxal phosphate binding protein 0.00509047
MYO1D myosin ID 0.00508257
SMAD6 SMAD family member 6 0.00508188
GPSM2 G-protein signaling modulator 2 0.00506916
GPR137B G protein-coupled receptor 137B 0.00506471
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.0050581
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 0.00505731
THYN1 thymocyte nuclear protein 1 0.00505221
DPYSL2 dihydropyrimidinase-like 2 0.00504152
OLFM4 olfactomedin 4 0.00501712
CISH cytokine inducible SH2-containing protein 0.00501034
LAPTM5 lysosomal protein transmembrane 5 0.00499987
HBB hemoglobin, beta 0.00498671
CETN2 centrin, EF-hand protein, 2 0.00498226
RNF43 ring finger protein 43 0.00498185
CCDC85B coiled-coil domain containing 85B 0.00495814
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.00495153
LTBP1 latent transforming growth factor beta binding protein 1 0.0049499
RBX1 ring-box 1, E3 ubiquitin protein ligase 0.00494314
CALML4 calmodulin-like 4 0.00493757
CCN2 cellular communication network factor 2 0.00493119
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.00492677
DUSP7 dual specificity phosphatase 7 0.00492208
AP2A2 adaptor-related protein complex 2, alpha 2 subunit 0.00490997
ICAM2 intercellular adhesion molecule 2 0.00490705
LYPLA1 lysophospholipase I 0.00490539
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 0.00490105
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.00489067
PRR5L proline rich 5 like 0.00488802
IFITM3 interferon induced transmembrane protein 3 0.00488074
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.00488023
DNASE1L3 deoxyribonuclease I-like 3 0.00487103
MRPS16 mitochondrial ribosomal protein S16 0.00486244
DSG3 desmoglein 3 0.00485983
SKP1 S-phase kinase-associated protein 1 0.00484671
COL8A1 collagen, type VIII, alpha 1 0.00484102
GRAMD2B GRAM domain containing 2B 0.0048378
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.00483602
ADORA2B adenosine A2b receptor 0.0048334

decreased expression

Symbol Name Standardized Value
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0192907
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.0142556
TENT5A terminal nucleotidyltransferase 5A -0.0140295
CXCL13 chemokine (C-X-C motif) ligand 13 -0.0133353
SFRP1 secreted frizzled-related protein 1 -0.0126362
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -0.0126115
IRS2 insulin receptor substrate 2 -0.012447
NPY1R neuropeptide Y receptor Y1 -0.0121498
CCL19 chemokine (C-C motif) ligand 19 -0.0112734
CXCL9 chemokine (C-X-C motif) ligand 9 -0.0109773
BEX1 brain expressed, X-linked 1 -0.0109156
LUM lumican -0.0100293
IFI44L interferon-induced protein 44-like -0.0100094
TNC tenascin C -0.00979339
HSPB8 heat shock 22kDa protein 8 -0.00975678
VLDLR very low density lipoprotein receptor -0.00954749
HSPA1A heat shock 70kDa protein 1A -0.00950352
APOD apolipoprotein D -0.00937288
COL15A1 collagen, type XV, alpha 1 -0.00920008
DUSP5 dual specificity phosphatase 5 -0.00909443
CTSL cathepsin L -0.00887749
ITGA7 integrin, alpha 7 -0.00885639
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.00884772
C3 complement component 3 -0.00881603
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.00880679
TGFBI transforming growth factor, beta-induced, 68kDa -0.00861947
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.00859932
RSRP1 arginine/serine-rich protein 1 -0.00844149
LXN latexin -0.00843662
TRIM22 tripartite motif containing 22 -0.00842914
ELOVL5 ELOVL fatty acid elongase 5 -0.00836595
CXCL10 chemokine (C-X-C motif) ligand 10 -0.00836242
ANKRD10 ankyrin repeat domain 10 -0.00832942
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.00828364
NPEPL1 aminopeptidase-like 1 -0.00827839
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase -0.00825443
POSTN periostin, osteoblast specific factor -0.00819696
SCD5 stearoyl-CoA desaturase 5 -0.00816455
FKBP11 FK506 binding protein 11, 19 kDa -0.00806602
LDOC1 leucine zipper, down-regulated in cancer 1 -0.00806392
MMP1 matrix metallopeptidase 1 -0.00801247
PTGER3 prostaglandin E receptor 3 (subtype EP3) -0.00791865
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -0.00789754
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.00788098
LMO3 LIM domain only 3 (rhombotin-like 2) -0.00786709
CKS2 CDC28 protein kinase regulatory subunit 2 -0.00765227
RET ret proto-oncogene -0.00763395
FN1 fibronectin 1 -0.00763206
EMP3 epithelial membrane protein 3 -0.00760665
SV2B synaptic vesicle glycoprotein 2B -0.00756339
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.00753018
GNAS GNAS complex locus -0.00750553
FGF13 fibroblast growth factor 13 -0.00741639
GOLGA8A golgin A8 family, member A -0.0073817
MFSD1 major facilitator superfamily domain containing 1 -0.00722109
HSPA6 heat shock 70kDa protein 6 (HSP70B') -0.00719592
FNDC3B fibronectin type III domain containing 3B -0.00719187
CALCA calcitonin-related polypeptide alpha -0.00716029
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) -0.00713679
KRT7 keratin 7, type II -0.00703231
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 -0.00702494
NOTCH2NL notch 2 N-terminal like -0.00694777
PCNA proliferating cell nuclear antigen -0.00694734
TSPYL2 TSPY-like 2 -0.00691698
TSPAN13 tetraspanin 13 -0.00686552
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 -0.00684533
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00682683
EDRF1 erythroid differentiation regulatory factor 1 -0.00680795
REEP1 receptor accessory protein 1 -0.00678692
TIMP1 TIMP metallopeptidase inhibitor 1 -0.00676585
TGFBR3 transforming growth factor, beta receptor III -0.00674458
TFPI2 tissue factor pathway inhibitor 2 -0.00670239
FAM13A family with sequence similarity 13, member A -0.00662722
PYGL phosphorylase, glycogen, liver -0.00662429
NEFH neurofilament, heavy polypeptide -0.00660152
IGSF1 immunoglobulin superfamily, member 1 -0.00659406
LONP2 lon peptidase 2, peroxisomal -0.00658379
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -0.00657334
VGF VGF nerve growth factor inducible -0.00656976
FLRT3 fibronectin leucine rich transmembrane protein 3 -0.00654278
XAF1 XIAP associated factor 1 -0.00653844
C1S complement component 1, s subcomponent -0.00648407
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 -0.00640114
CTSC cathepsin C -0.00634204
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.00632539
MAGEA12 melanoma antigen family A12 -0.00627213
SLC39A14 solute carrier family 39 (zinc transporter), member 14 -0.00626687
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 -0.00624969
LY6E lymphocyte antigen 6 complex, locus E -0.00624439
RUFY3 RUN and FYVE domain containing 3 -0.00621961
ACSL1 acyl-CoA synthetase long-chain family member 1 -0.00621057
S100B S100 calcium binding protein B -0.00620362
MAGEA1 melanoma antigen family A1 -0.00619129
FBXW12 F-box and WD repeat domain containing 12 -0.00617171
MCM2 minichromosome maintenance complex component 2 -0.00615571
PCDH9 protocadherin 9 -0.00614132
AUH AU RNA binding protein/enoyl-CoA hydratase -0.00613972
CSAD cysteine sulfinic acid decarboxylase -0.00612955
CD320 CD320 molecule -0.00612497
TUBB6 tubulin, beta 6 class V -0.00610579
THBS4 thrombospondin 4 -0.00607694
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00607522
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) -0.00605743
S100A10 S100 calcium binding protein A10 -0.00602474
TMX4 thioredoxin-related transmembrane protein 4 -0.00601631
PCSK2 proprotein convertase subtilisin/kexin type 2 -0.00601568
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -0.00600147
CHPT1 choline phosphotransferase 1 -0.00599646
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.00594175
SAMD4A sterile alpha motif domain containing 4A -0.00592597
TRIM9 tripartite motif containing 9 -0.00590486
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A -0.00589477
CHI3L2 chitinase 3-like 2 -0.00588822
CHGB chromogranin B -0.00588606
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.0058476
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.00583882
SPP1 secreted phosphoprotein 1 -0.00583691
OPHN1 oligophrenin 1 -0.00582838
PNN pinin, desmosome associated protein -0.00581832
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene -0.00581681
RPL10 ribosomal protein L10 -0.00580392
RSAD2 radical S-adenosyl methionine domain containing 2 -0.0057757
RGS1 regulator of G-protein signaling 1 -0.00577273
DCHS1 dachsous cadherin-related 1 -0.00576123
RPS27L ribosomal protein S27-like -0.00574995
MIR22HG MIR22 host gene -0.00574574
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -0.00574082
BST2 bone marrow stromal cell antigen 2 -0.00573033
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00571852
ZBTB20 zinc finger and BTB domain containing 20 -0.00569395
GRB14 growth factor receptor-bound protein 14 -0.00569239
MAMLD1 mastermind-like domain containing 1 -0.00564417
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene) -0.00561751
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) -0.00560426
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 -0.0055982
GZMK granzyme K (granzyme 3; tryptase II) -0.00559813
PILRB paired immunoglobin-like type 2 receptor beta -0.00559464
EPS8 epidermal growth factor receptor pathway substrate 8 -0.00558884
RABGGTB Rab geranylgeranyltransferase, beta subunit -0.00557762
MX1 MX dynamin-like GTPase 1 -0.00555707
ELOVL2 ELOVL fatty acid elongase 2 -0.00554839
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -0.00554406
CXCL11 chemokine (C-X-C motif) ligand 11 -0.00552014
PNISR PNN-interacting serine/arginine-rich protein -0.00550961
DCT dopachrome tautomerase -0.0054966
ZNF160 zinc finger protein 160 -0.00549288
PTP4A1 protein tyrosine phosphatase type IVA, member 1 -0.00547094
FGL2 fibrinogen-like 2 -0.00546875
NPTX1 neuronal pentraxin I -0.00546007
FHL2 four and a half LIM domains 2 -0.00545845
SPTSSA serine palmitoyltransferase, small subunit A -0.0054467
CD37 CD37 molecule -0.00542944
SLC35G2 solute carrier family 35, member G2 -0.00542679
TIMP4 TIMP metallopeptidase inhibitor 4 -0.00542517
CD70 CD70 molecule -0.00541585
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) -0.00540215
ISG15 ISG15 ubiquitin-like modifier -0.00539829
RIN2 Ras and Rab interactor 2 -0.00539517
MIA melanoma inhibitory activity -0.00538029
PRPF4B pre-mRNA processing factor 4B -0.00534892
SECISBP2 SECIS binding protein 2 -0.00534341
RSRC2 arginine/serine-rich coiled-coil 2 -0.00533766
SSBP2 single-stranded DNA binding protein 2 -0.00533246
CHRDL1 chordin-like 1 -0.00532686
PALMD palmdelphin -0.00532683
PRNP prion protein -0.00532667
LTF lactotransferrin -0.0053225
PTPRM protein tyrosine phosphatase, receptor type, M -0.00532158
DCLK1 doublecortin-like kinase 1 -0.00532092
KANK1 KN motif and ankyrin repeat domains 1 -0.00527937
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.00527258
MITF microphthalmia-associated transcription factor -0.00526044
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00526037
TAOK3 TAO kinase 3 -0.00526034
DYNLL1 dynein, light chain, LC8-type 1 -0.00526023
SPIB Spi-B transcription factor (Spi-1/PU.1 related) -0.00523956
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 -0.00522883
SCAF4 SR-related CTD-associated factor 4 -0.00522876
FRS2 fibroblast growth factor receptor substrate 2 -0.00521326
PPT2 palmitoyl-protein thioesterase 2 -0.00520328
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2 -0.00517749
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -0.0051573
EPB41L3 erythrocyte membrane protein band 4.1-like 3 -0.00513473
RGS16 regulator of G-protein signaling 16 -0.00510938
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 -0.00510932
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced -0.00510096
SETD6 SET domain containing 6 -0.00509157
PLAAT3 phospholipase A and acyltransferase 3 -0.00509083
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00507967
TBX3 T-box 3 -0.00507085
STAT1 signal transducer and activator of transcription 1, 91kDa -0.00506911
HLA-C major histocompatibility complex, class I, C -0.00506786
TENM1 teneurin transmembrane protein 1 -0.0050671
CCL8 chemokine (C-C motif) ligand 8 -0.00506336
CALCB calcitonin-related polypeptide beta -0.00506292
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor -0.00506203
OPN3 opsin 3 -0.00505967
MKNK2 MAP kinase interacting serine/threonine kinase 2 -0.00503996
ERBB3 erb-b2 receptor tyrosine kinase 3 -0.00503948
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase -0.00503931
MAGEA3 melanoma antigen family A3 -0.00502526
KPNB1 karyopherin (importin) beta 1 -0.00502411
CTPS1 CTP synthase 1 -0.00501316
XIC X chromosome inactivation center -0.00500959
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.00500812
CDH18 cadherin 18, type 2 -0.00499725
KCNK3 potassium channel, two pore domain subfamily K, member 3 -0.00499332
EGR1 early growth response 1 -0.00498909
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 -0.00497219
SUGP2 SURP and G patch domain containing 2 -0.00497147
NKTR natural killer cell triggering receptor -0.00496806
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15 -0.00496438
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 -0.00496134
BAZ2B bromodomain adjacent to zinc finger domain, 2B -0.00495944
BCHE butyrylcholinesterase -0.00495525
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.00494788
GPNMB glycoprotein (transmembrane) nmb -0.00494764
NR4A2 nuclear receptor subfamily 4, group A, member 2 -0.00493824
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 -0.00493753
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A -0.00493473
RUFY2 RUN and FYVE domain containing 2 -0.00493047
HK2 hexokinase 2 -0.00492363
PLXNC1 plexin C1 -0.0049177
C8ORF4 chromosome 8 open reading frame 4 -0.00491711
KCTD3 potassium channel tetramerization domain containing 3 -0.00490985
MPZ myelin protein zero -0.00490857
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -0.00490721
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) -0.00490592
ADIPOQ adiponectin, C1Q and collagen domain containing -0.00490254
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00489823
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -0.00489573
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.00489254
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.00488244
AOC3 amine oxidase, copper containing 3 -0.00488235
NVL nuclear VCP-like -0.00487656
STK26 serine/threonine protein kinase 26 -0.00485931
MAGEA4 melanoma antigen family A4 -0.00485723
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -0.00485579
AACS acetoacetyl-CoA synthetase -0.00485046
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) -0.00484669
IL6 interleukin 6 -0.00482839
CCNG2 cyclin G2 -0.00482748
CEBPB CCAAT/enhancer binding protein (C/EBP), beta -0.00481926
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -0.00481228
HLA-DMB major histocompatibility complex, class II, DM beta -0.00480073
HIST1H2BK histone cluster 1, H2bk -0.00479757
NGFR nerve growth factor receptor -0.00479055
CCNL2 cyclin L2 -0.00479045
SSX1 synovial sarcoma, X breakpoint 1 -0.0047832
LRP4 low density lipoprotein receptor-related protein 4 -0.004781