| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | additional sex combs like transcriptional regulator 1|This gene is similar to the Drosophila additional sex combs gene, which encodes a chromatin-binding protein required for normal determination of segment identity in the developing embryo. The protein is a member of the Polycomb group of proteins, which are necessary for the maintenance of stable repression of homeotic and other loci. The protein is thought to disrupt chromatin in localized areas, enhancing transcription of certain genes while repressing the transcription of other genes. The protein encoded by this gene functions as a ligand-dependent co-activator for retinoic acid receptor in cooperation with nuclear receptor coactivator 1. Mutations in this gene are associated with myelodysplastic syndromes and chronic myelomonocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 171023) |
| External Link | https://ncbi.nlm.nih.gov/gene/171023 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the ASXL1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA1A | heat shock 70kDa protein 1A | 0.0106756 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0101944 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00970429 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00947504 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.00903878 |
| SLC38A1 | solute carrier family 38, member 1 | 0.00852683 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00749086 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.0074227 |
| S100A8 | S100 calcium binding protein A8 | 0.00735406 |
| S100A9 | S100 calcium binding protein A9 | 0.00718033 |
| AMOTL2 | angiomotin like 2 | 0.00716658 |
| PDGFC | platelet derived growth factor C | 0.0070562 |
| PLK2 | polo-like kinase 2 | 0.00704847 |
| CRYAB | crystallin, alpha B | 0.00703487 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00699065 |
| CFB | complement factor B | 0.00697616 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.00686015 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 0.00685154 |
| LCN2 | lipocalin 2 | 0.00670897 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00670013 |
| RND3 | Rho family GTPase 3 | 0.00659805 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00656631 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.00653177 |
| KRT19 | keratin 19, type I | 0.00648185 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | 0.00639368 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.00637617 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0063666 |
| SC5D | sterol-C5-desaturase | 0.00635861 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00634597 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.00629224 |
| THBS1 | thrombospondin 1 | 0.00625224 |
| PXDC1 | PX domain containing 1 | 0.00621242 |
| MSRA | methionine sulfoxide reductase A | 0.00617019 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.00609946 |
| STC2 | stanniocalcin 2 | 0.00606593 |
| DNM1L | dynamin 1-like | 0.00597123 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.00596828 |
| CNN3 | calponin 3, acidic | 0.0059559 |
| ANXA1 | annexin A1 | 0.00593064 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00589371 |
| ANXA3 | annexin A3 | 0.00580519 |
| G0S2 | G0/G1 switch 2 | 0.00579263 |
| HDAC9 | histone deacetylase 9 | 0.00578695 |
| YBX3 | Y box binding protein 3 | 0.00578388 |
| ACKR3 | atypical chemokine receptor 3 | 0.00577978 |
| PLAU | plasminogen activator, urokinase | 0.0057249 |
| HIST1H2AE | histone cluster 1, H2ae | 0.00571758 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.00562414 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | 0.00561707 |
| HSPB1 | heat shock 27kDa protein 1 | 0.00556369 |
| CREB1 | cAMP responsive element binding protein 1 | 0.00553022 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) | 0.0055185 |
| TSPAN12 | tetraspanin 12 | 0.00548624 |
| MMP10 | matrix metallopeptidase 10 | 0.00545088 |
| WASF1 | WAS protein family, member 1 | 0.00544093 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | 0.00543522 |
| IFRD1 | interferon-related developmental regulator 1 | 0.00538424 |
| TES | testin LIM domain protein | 0.00534182 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00532347 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.00530443 |
| CSTA | cystatin A (stefin A) | 0.00525336 |
| TUFT1 | tuftelin 1 | 0.00522543 |
| IFI44L | interferon-induced protein 44-like | 0.00521567 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.00520146 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.00514201 |
| MFAP5 | microfibrillar associated protein 5 | 0.00513034 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0051303 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.00513025 |
| MMP7 | matrix metallopeptidase 7 | 0.00511178 |
| FADS3 | fatty acid desaturase 3 | 0.00508137 |
| NOX4 | NADPH oxidase 4 | 0.00506232 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.00505217 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.00502282 |
| BAG2 | BCL2-associated athanogene 2 | 0.00496279 |
| CRY1 | cryptochrome circadian clock 1 | 0.00496019 |
| INHBA | inhibin, beta A | 0.00495083 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | 0.00494593 |
| ANKRD28 | ankyrin repeat domain 28 | 0.00494548 |
| TOX3 | TOX high mobility group box family member 3 | 0.00493856 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00489962 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.00487552 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00485905 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.00485415 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.00484132 |
| NXN | nucleoredoxin | 0.0048196 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.00481557 |
| STK38 | serine/threonine kinase 38 | 0.00479353 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.00478981 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0047589 |
| DUSP10 | dual specificity phosphatase 10 | 0.00473829 |
| NPTN | neuroplastin | 0.00473391 |
| HIST1H2AC | histone cluster 1, H2ac | 0.00470394 |
| C5ORF28 | chromosome 5 open reading frame 28 | 0.00469942 |
| PERP | PERP, TP53 apoptosis effector | 0.00469112 |
| PTK2 | protein tyrosine kinase 2 | 0.00469015 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.00468444 |
| WBP5 | WW domain binding protein 5 | 0.00468439 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.00467219 |
| S100A14 | S100 calcium binding protein A14 | 0.00465145 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00464433 |
| RIT1 | Ras-like without CAAX 1 | 0.00462906 |
| CCDC92 | coiled-coil domain containing 92 | 0.00460859 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.00460671 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | 0.00460203 |
| EMP1 | epithelial membrane protein 1 | 0.00460134 |
| TRIB3 | tribbles pseudokinase 3 | 0.00460115 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.00459899 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.00459036 |
| CCN3 | cellular communication network factor 3 | 0.00457231 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | 0.00456503 |
| STK26 | serine/threonine protein kinase 26 | 0.00456359 |
| RHOB | ras homolog family member B | 0.00455756 |
| SLC38A2 | solute carrier family 38, member 2 | 0.00455694 |
| CLGN | calmegin | 0.00455033 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00454708 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.00453695 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | 0.00452744 |
| TSC22D2 | TSC22 domain family, member 2 | 0.00450092 |
| CLEC3B | C-type lectin domain family 3, member B | 0.00449926 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.004475 |
| CD9 | CD9 molecule | 0.00447005 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 0.00446681 |
| HSPA2 | heat shock 70kDa protein 2 | 0.00446634 |
| RAI14 | retinoic acid induced 14 | 0.00445973 |
| AZU1 | azurocidin 1 | 0.00444524 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.00444456 |
| FRY | furry homolog (Drosophila) | 0.00443987 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.00443633 |
| MNDA | myeloid cell nuclear differentiation antigen | 0.00443034 |
| RNF167 | ring finger protein 167 | 0.00441434 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 0.00440803 |
| WASHC4 | WASH complex subunit 4 | 0.00439405 |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | 0.00438998 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00437776 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.00437386 |
| H1-2 | H1.2 linker histone, cluster member | 0.00436838 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.00435096 |
| USP18 | ubiquitin specific peptidase 18 | 0.00433077 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.00433054 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00432668 |
| SPART | spartin | 0.0043248 |
| IPO13 | importin 13 | 0.00431623 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.00427821 |
| FGL2 | fibrinogen-like 2 | 0.00424586 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.00423268 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.00421492 |
| RASA1 | RAS p21 protein activator (GTPase activating protein) 1 | 0.00421491 |
| FRMD4B | FERM domain containing 4B | 0.00420622 |
| COL11A1 | collagen, type XI, alpha 1 | 0.00419915 |
| YPEL5 | yippee-like 5 (Drosophila) | 0.00418908 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0041827 |
| TLN1 | talin 1 | 0.00417263 |
| REG1A | regenerating islet-derived 1 alpha | 0.00417009 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.00416722 |
| WTAP | Wilms tumor 1 associated protein | 0.00416277 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 | 0.00414476 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.00414381 |
| KRT23 | keratin 23, type I | 0.00414148 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0041396 |
| WASL | Wiskott-Aldrich syndrome-like | 0.00413571 |
| IRS2 | insulin receptor substrate 2 | 0.00413305 |
| ANKRD10 | ankyrin repeat domain 10 | 0.00410913 |
| LARP6 | La ribonucleoprotein domain family, member 6 | 0.00409769 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | 0.00408938 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00408488 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.00408297 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.00408294 |
| ASS1 | argininosuccinate synthase 1 | 0.00408269 |
| PLAT | plasminogen activator, tissue | 0.00405677 |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 | 0.00404467 |
| ARGLU1 | arginine and glutamate rich 1 | 0.00404098 |
| COMP | cartilage oligomeric matrix protein | 0.00403005 |
| SGMS1 | sphingomyelin synthase 1 | 0.00402702 |
| PLBD1 | phospholipase B domain containing 1 | 0.0040247 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | 0.00401179 |
| CEL | carboxyl ester lipase | 0.00399979 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | 0.00399746 |
| HIST1H2BK | histone cluster 1, H2bk | 0.0039917 |
| RORA | RAR-related orphan receptor A | 0.00398314 |
| ANKRD12 | ankyrin repeat domain 12 | 0.00397542 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.00396975 |
| RTN2 | reticulon 2 | 0.00395246 |
| SORT1 | sortilin 1 | 0.0039472 |
| RGS2 | regulator of G-protein signaling 2 | 0.00394573 |
| ALOX5 | arachidonate 5-lipoxygenase | 0.00393756 |
| GCA | grancalcin, EF-hand calcium binding protein | 0.00392656 |
| PDLIM4 | PDZ and LIM domain 4 | 0.00391719 |
| PPL | periplakin | 0.00391467 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.00390446 |
| NAV3 | neuron navigator 3 | 0.00390264 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.00390046 |
| TSPAN7 | tetraspanin 7 | 0.00389932 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.00389925 |
| MAGEB2 | melanoma antigen family B2 | 0.00389414 |
| DAPK1 | death-associated protein kinase 1 | 0.00389005 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.00388999 |
| NOTCH2 | notch 2 | 0.00388927 |
| KRT7 | keratin 7, type II | 0.00388791 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 0.00388237 |
| EVI2A | ecotropic viral integration site 2A | 0.00384042 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.00383345 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.00382701 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.00382624 |
| VNN1 | vanin 1 | 0.00382396 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | 0.00382294 |
| GLS | glutaminase | 0.00381692 |
| UXS1 | UDP-glucuronate decarboxylase 1 | 0.00381634 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.00380501 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.00380179 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.00380144 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 0.00380113 |
| TCTA | T-cell leukemia translocation altered | 0.00379986 |
| SULF1 | sulfatase 1 | 0.00379985 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.00379947 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.00379708 |
| KLK6 | kallikrein-related peptidase 6 | 0.00379628 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.00379452 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.00378956 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.00378126 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A | 0.00377487 |
| PTK2B | protein tyrosine kinase 2 beta | 0.00377472 |
| DSE | dermatan sulfate epimerase | 0.00377347 |
| INPP1 | inositol polyphosphate-1-phosphatase | 0.00377053 |
| CLDN1 | claudin 1 | 0.00376687 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | 0.00375341 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00374807 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00374668 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00374622 |
| MYO6 | myosin VI | 0.00374442 |
| COMT | catechol-O-methyltransferase | 0.00374236 |
| ZNF83 | zinc finger protein 83 | 0.00374009 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00373595 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | 0.00373307 |
| USP32P2 | ubiquitin specific peptidase 32 pseudogene 2 | 0.00373106 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.00372956 |
| PRSS8 | protease, serine, 8 | 0.00371525 |
| RNF19B | ring finger protein 19B | 0.00371001 |
| ACVR1 | activin A receptor, type I | 0.00370984 |
| RNF146 | ring finger protein 146 | 0.00370753 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.00370524 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00369964 |
| EXT1 | exostosin glycosyltransferase 1 | 0.00369198 |
| NFE2 | nuclear factor, erythroid 2 | 0.00369138 |
| GTPBP2 | GTP binding protein 2 | 0.00367796 |
| CDC37L1 | cell division cycle 37-like 1 | 0.00367569 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | 0.00367366 |
| RCAN2 | regulator of calcineurin 2 | 0.00367 |
| KLF9 | Kruppel-like factor 9 | 0.00366827 |
| CLCN4 | chloride channel, voltage-sensitive 4 | 0.00366787 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00366783 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DLK1 | delta-like 1 homolog (Drosophila) | -0.0105001 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00985879 |
| C7 | complement component 7 | -0.00798951 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.00752888 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00745658 |
| PLK1 | polo-like kinase 1 | -0.00742175 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.00736401 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0071928 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00697097 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.00692407 |
| ASF1B | anti-silencing function 1B histone chaperone | -0.0066608 |
| TFF1 | trefoil factor 1 | -0.00649361 |
| LIG1 | ligase I, DNA, ATP-dependent | -0.00648439 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00631117 |
| TSPAN8 | tetraspanin 8 | -0.00626192 |
| HBB | hemoglobin, beta | -0.00621122 |
| KIF20A | kinesin family member 20A | -0.00620638 |
| COQ8A | coenzyme Q8A | -0.0061845 |
| TMEM255A | transmembrane protein 255A | -0.00609306 |
| CCL21 | chemokine (C-C motif) ligand 21 | -0.00606994 |
| METRN | meteorin, glial cell differentiation regulator | -0.00599755 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | -0.00594862 |
| FCGBP | Fc fragment of IgG binding protein | -0.00587843 |
| NTS | neurotensin | -0.00585041 |
| GOLM1 | golgi membrane protein 1 | -0.00577813 |
| SHCBP1 | SHC SH2-domain binding protein 1 | -0.00577469 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00571431 |
| HOPX | HOP homeobox | -0.00563216 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00557912 |
| TYRP1 | tyrosinase-related protein 1 | -0.00548137 |
| CGA | glycoprotein hormones, alpha polypeptide | -0.00547306 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -0.0053778 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | -0.00528767 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00521413 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | -0.00516831 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00515115 |
| TMSB15A | thymosin beta 15a | -0.00509654 |
| SFTPA2 | surfactant protein A2 | -0.00502349 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | -0.00497481 |
| TPX2 | TPX2, microtubule-associated | -0.00495334 |
| MAGEA3 | melanoma antigen family A3 | -0.00493049 |
| COL9A3 | collagen, type IX, alpha 3 | -0.00492753 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.00491252 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.0049109 |
| EGR2 | early growth response 2 | -0.00490637 |
| CSTB | cystatin B (stefin B) | -0.00489755 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | -0.0048848 |
| CH25H | cholesterol 25-hydroxylase | -0.00486476 |
| CYB561 | cytochrome b561 | -0.00485534 |
| PTCH1 | patched 1 | -0.00484299 |
| SIRT3 | sirtuin 3 | -0.00484172 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.00483942 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00483778 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | -0.00483627 |
| OPHN1 | oligophrenin 1 | -0.00479785 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.0047975 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | -0.00477138 |
| FAM162A | family with sequence similarity 162, member A | -0.00476734 |
| DMD | dystrophin | -0.0047653 |
| DMAC2L | distal membrane arm assembly component 2 like | -0.0047468 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.00473303 |
| PRDX2 | peroxiredoxin 2 | -0.00473028 |
| AUTS2 | autism susceptibility candidate 2 | -0.00472919 |
| FABP7 | fatty acid binding protein 7, brain | -0.00469669 |
| PRKD3 | protein kinase D3 | -0.00469216 |
| ERGIC3 | ERGIC and golgi 3 | -0.00467889 |
| RPN2 | ribophorin II | -0.00466878 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | -0.00463007 |
| EDN3 | endothelin 3 | -0.004624 |
| CHKB | choline kinase beta | -0.00460745 |
| MATN2 | matrilin 2 | -0.00460297 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | -0.00458885 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.004583 |
| MT1H | metallothionein 1H | -0.00457372 |
| COL6A2 | collagen, type VI, alpha 2 | -0.00456576 |
| RNASEH2A | ribonuclease H2, subunit A | -0.00455109 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.00450922 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00450886 |
| NDNF | neuron-derived neurotrophic factor | -0.00450295 |
| KRT1 | keratin 1, type II | -0.00447961 |
| LAGE3 | L antigen family, member 3 | -0.00447132 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00446418 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.00446388 |
| MARCKSL1 | MARCKS-like 1 | -0.00446102 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -0.00443577 |
| DSG1 | desmoglein 1 | -0.00439565 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00438209 |
| CCND1 | cyclin D1 | -0.00435724 |
| HYOU1 | hypoxia up-regulated 1 | -0.00434238 |
| GM2A | GM2 ganglioside activator | -0.0043313 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | -0.00432659 |
| CNN2 | calponin 2 | -0.00432558 |
| ALDOC | aldolase C, fructose-bisphosphate | -0.00432418 |
| FERMT1 | fermitin family member 1 | -0.00431241 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | -0.00429942 |
| TDP1 | tyrosyl-DNA phosphodiesterase 1 | -0.00428908 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00427905 |
| A2M | alpha-2-macroglobulin | -0.00427325 |
| COL6A1 | collagen, type VI, alpha 1 | -0.00427198 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | -0.0042462 |
| POPDC3 | popeye domain containing 3 | -0.00424035 |
| XPO7 | exportin 7 | -0.00423731 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0042157 |
| RFX5 | regulatory factor X, 5 (influences HLA class II expression) | -0.00420094 |
| C21ORF33 | chromosome 21 open reading frame 33 | -0.0041954 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.00419449 |
| ATP10B | ATPase, class V, type 10B | -0.00418672 |
| TCTN2 | tectonic family member 2 | -0.00418521 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.00418229 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | -0.00418186 |
| SFTPB | surfactant protein B | -0.00418069 |
| RUNX3 | runt-related transcription factor 3 | -0.00416897 |
| GTSE1 | G-2 and S-phase expressed 1 | -0.00413611 |
| EIF3I | eukaryotic translation initiation factor 3, subunit I | -0.00412517 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -0.00411939 |
| GPX2 | glutathione peroxidase 2 | -0.00411789 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.00411046 |
| KIF3B | kinesin family member 3B | -0.00409921 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | -0.0040984 |
| CA12 | carbonic anhydrase XII | -0.00409277 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.00408928 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor | -0.00408095 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.00408008 |
| MLPH | melanophilin | -0.00405565 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00405076 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00404947 |
| ADD3 | adducin 3 (gamma) | -0.00404881 |
| UBL4A | ubiquitin-like 4A | -0.00403892 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.00403638 |
| EMILIN1 | elastin microfibril interfacer 1 | -0.0040297 |
| BIRC5 | baculoviral IAP repeat containing 5 | -0.00402192 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -0.00401707 |
| LEFTY1 | left-right determination factor 1 | -0.00401463 |
| NAAA | N-acylethanolamine acid amidase | -0.00401358 |
| RRM1 | ribonucleotide reductase M1 | -0.00399749 |
| CYTIP | cytohesin 1 interacting protein | -0.00397654 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -0.00397498 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.00397388 |
| DCHS1 | dachsous cadherin-related 1 | -0.00395583 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.00394041 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | -0.00393577 |
| ZNF217 | zinc finger protein 217 | -0.0039296 |
| CENPF | centromere protein F, 350/400kDa | -0.0039215 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.00392011 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | -0.00391188 |
| CCR5 | chemokine (C-C motif) receptor 5 (gene/pseudogene) | -0.00390151 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00388197 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00388069 |
| PADI2 | peptidyl arginine deiminase, type II | -0.0038747 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.00386532 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | -0.00386473 |
| TLCD3A | TLC domain containing 3A | -0.00386294 |
| IL27RA | interleukin 27 receptor, alpha | -0.00386263 |
| SNRPA | small nuclear ribonucleoprotein polypeptide A | -0.00385599 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | -0.00385344 |
| DGLUCY | D-glutamate cyclase | -0.00384898 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -0.003831 |
| MT1HL1 | metallothionein 1H-like 1 | -0.0038307 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.00382964 |
| AK4 | adenylate kinase 4 | -0.00382343 |
| CDC42EP4 | CDC42 effector protein (Rho GTPase binding) 4 | -0.00380958 |
| IRF4 | interferon regulatory factor 4 | -0.00379016 |
| COCH | cochlin | -0.00378995 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00378855 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.00378049 |
| EGR3 | early growth response 3 | -0.00377149 |
| VWF | von Willebrand factor | -0.00376954 |
| USP13 | ubiquitin specific peptidase 13 (isopeptidase T-3) | -0.003768 |
| HELLS | helicase, lymphoid-specific | -0.003765 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 | -0.00376203 |
| CTSH | cathepsin H | -0.00375582 |
| THYN1 | thymocyte nuclear protein 1 | -0.00375088 |
| B3GNT1 | -0.00375056 | |
| BTG2 | BTG family, member 2 | -0.00374437 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | -0.00373984 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | -0.00373933 |
| LAMA4 | laminin, alpha 4 | -0.00373039 |
| GUCY2C | guanylate cyclase 2C | -0.00372797 |
| TFDP1 | transcription factor Dp-1 | -0.00372633 |
| NEBL | nebulette | -0.00372572 |
| MIA | melanoma inhibitory activity | -0.00372514 |
| SSR4 | signal sequence receptor, delta | -0.00371116 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00370915 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00370811 |
| PEBP1 | phosphatidylethanolamine binding protein 1 | -0.00370803 |
| DCTD | dCMP deaminase | -0.00370767 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.00370461 |
| ITGB7 | integrin, beta 7 | -0.00370062 |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | -0.00369752 |
| CPNE1 | copine I | -0.00369199 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | -0.00368954 |
| DHTKD1 | dehydrogenase E1 and transketolase domain containing 1 | -0.00368437 |
| GLB1L2 | galactosidase, beta 1-like 2 | -0.00368021 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.00367957 |
| CDCA3 | cell division cycle associated 3 | -0.00365953 |
| WNT4 | wingless-type MMTV integration site family, member 4 | -0.00365917 |
| BTNL8 | butyrophilin-like 8 | -0.00365667 |
| DDHD2 | DDHD domain containing 2 | -0.00365268 |
| MRC2 | mannose receptor, C type 2 | -0.00365214 |
| TUBB2A | tubulin, beta 2A class IIa | -0.0036464 |
| STMN1 | stathmin 1 | -0.0036432 |
| MCM2 | minichromosome maintenance complex component 2 | -0.00363492 |
| AHCY | adenosylhomocysteinase | -0.00362555 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.00362496 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00361976 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.00361938 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.00361241 |
| CETN2 | centrin, EF-hand protein, 2 | -0.00360923 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) | -0.00360762 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | -0.00360385 |
| FBXO2 | F-box protein 2 | -0.00360124 |
| NSG1 | neuron specific gene family member 1 | -0.00359975 |
| POLD1 | polymerase (DNA directed), delta 1, catalytic subunit | -0.00359485 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.00359442 |
| SFTPC | surfactant protein C | -0.00358889 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.00358797 |
| PRKCA | protein kinase C, alpha | -0.00358675 |
| MSH6 | mutS homolog 6 | -0.00358416 |
| STEAP3 | STEAP family member 3, metalloreductase | -0.0035786 |
| ADCY3 | adenylate cyclase 3 | -0.00357813 |
| ATOX1 | antioxidant 1 copper chaperone | -0.003578 |
| FBL | fibrillarin | -0.00357619 |
| GINS3 | GINS complex subunit 3 (Psf3 homolog) | -0.003571 |
| KARS1 | lysyl-tRNA synthetase 1 | -0.0035678 |
| EXO1 | exonuclease 1 | -0.00356731 |
| DEPDC1B | DEP domain containing 1B | -0.00356223 |
| PODXL | podocalyxin-like | -0.00355829 |
| H1-10 | H1.10 linker histone | -0.0035486 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.00354678 |
| ADGRE1 | adhesion G protein-coupled receptor E1 | -0.00353622 |
| OLFM1 | olfactomedin 1 | -0.0035346 |
| ANXA6 | annexin A6 | -0.00353321 |
| ORC1 | origin recognition complex, subunit 1 | -0.003533 |
| MAGEA12 | melanoma antigen family A12 | -0.00352823 |
| ELAPOR1 | endosome-lysosome associated apoptosis and autophagy regulator 1 | -0.00352606 |
| TRIP13 | thyroid hormone receptor interactor 13 | -0.00352516 |
| MRPL17 | mitochondrial ribosomal protein L17 | -0.00352399 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | -0.00352292 |
| PIMREG | PICALM interacting mitotic regulator | -0.00351275 |
| GPR171 | G protein-coupled receptor 171 | -0.00350979 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | -0.00350576 |
| NKX2-1 | NK2 homeobox 1 | -0.00349697 |
| SELENBP1 | selenium binding protein 1 | -0.00349509 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.00349487 |
| HMGB3 | high mobility group box 3 | -0.0034931 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.00349082 |
| LRP4 | low density lipoprotein receptor-related protein 4 | -0.00348702 |
| SLC22A18 | solute carrier family 22, member 18 | -0.00348295 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.00348236 |
