| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | AT7519 perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the AT7519_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.2213 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.187373 |
| PODXL | podocalyxin-like | 0.153133 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.144027 |
| NAV1 | neuron navigator 1 | 0.107859 |
| AHNAK | AHNAK nucleoprotein | 0.0954249 |
| MAP1B | microtubule-associated protein 1B | 0.0928209 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0922315 |
| LOX | lysyl oxidase | 0.0810416 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0802947 |
| CD44 | CD44 molecule (Indian blood group) | 0.0793906 |
| DST | dystonin | 0.0775206 |
| COL5A1 | collagen, type V, alpha 1 | 0.0773448 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0769897 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0688627 |
| B2M | beta-2-microglobulin | 0.0628725 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0619937 |
| POTEF | POTE ankyrin domain family, member F | 0.0606535 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0601718 |
| ANXA2 | annexin A2 | 0.0582951 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0579614 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0578835 |
| MX2 | MX dynamin-like GTPase 2 | 0.0570207 |
| COL3A1 | collagen, type III, alpha 1 | 0.0564593 |
| ASPH | aspartate beta-hydroxylase | 0.0535518 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0523994 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0511216 |
| GLIS3 | GLIS family zinc finger 3 | 0.0497206 |
| RIGI | RNA sensor RIG-I | 0.0485336 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0484348 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0480613 |
| THBS2 | thrombospondin 2 | 0.0474795 |
| RNF213 | ring finger protein 213 | 0.046407 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0463368 |
| SUCNR1 | succinate receptor 1 | 0.0456012 |
| COL5A2 | collagen, type V, alpha 2 | 0.045332 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0449377 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.043333 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0427405 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0424541 |
| SP100 | SP100 nuclear antigen | 0.0424241 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0423361 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0415145 |
| TMSB4X | thymosin beta 4, X-linked | 0.0413371 |
| VEGFC | vascular endothelial growth factor C | 0.0413012 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0411477 |
| LDHA | lactate dehydrogenase A | 0.040948 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0407233 |
| CDH13 | cadherin 13 | 0.0390023 |
| SEPTIN9 | septin 9 | 0.0387988 |
| PLAT | plasminogen activator, tissue | 0.0382529 |
| FN1 | fibronectin 1 | 0.0381682 |
| VIM | vimentin | 0.0381638 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0375905 |
| PRSS23 | protease, serine, 23 | 0.0368753 |
| VCL | vinculin | 0.0362308 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.0354289 |
| LMNA | lamin A/C | 0.0351718 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0349928 |
| MB21D2 | Mab-21 domain containing 2 | 0.0349177 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0341038 |
| RUNX1 | runt-related transcription factor 1 | 0.0334994 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0328358 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0327206 |
| TPM3 | tropomyosin 3 | 0.032295 |
| EFNA5 | ephrin-A5 | 0.0319982 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0318434 |
| NEK7 | NIMA-related kinase 7 | 0.0317102 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0312759 |
| CDK6 | cyclin-dependent kinase 6 | 0.0311727 |
| LAMB1 | laminin, beta 1 | 0.0307397 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0302739 |
| CENPF | centromere protein F, 350/400kDa | 0.0302439 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0301948 |
| CUX1 | cut-like homeobox 1 | 0.0296202 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.0292057 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0291781 |
| MYADM | myeloid-associated differentiation marker | 0.0291371 |
| DGKG | diacylglycerol kinase, gamma 90kDa | 0.0289586 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0285511 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0283038 |
| PLXNA2 | plexin A2 | 0.0282263 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.027919 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0278549 |
| RNF144A | ring finger protein 144A | 0.0276511 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0276177 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0275646 |
| DCLK2 | doublecortin-like kinase 2 | 0.0275266 |
| CEP170 | centrosomal protein 170kDa | 0.0274893 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0274193 |
| FSTL1 | follistatin-like 1 | 0.0270463 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0269669 |
| TPM4 | tropomyosin 4 | 0.0267016 |
| LRRC17 | leucine rich repeat containing 17 | 0.0266529 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0263334 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | 0.0263026 |
| TAOK1 | TAO kinase 1 | 0.0262575 |
| PGK1 | phosphoglycerate kinase 1 | 0.0261178 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0253898 |
| RRM2 | ribonucleotide reductase M2 | 0.0253897 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0831013 |
| MT2A | metallothionein 2A | -0.0718432 |
| TMSB10 | thymosin beta 10 | -0.069315 |
| NDRG1 | N-myc downstream regulated 1 | -0.0609933 |
| RPL37A | ribosomal protein L37a | -0.0423581 |
| RPS6 | ribosomal protein S6 | -0.0367737 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0363517 |
| RPLP2 | ribosomal protein, large, P2 | -0.0345721 |
| PTMA | prothymosin, alpha | -0.0345343 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0336177 |
| RPS3 | ribosomal protein S3 | -0.0323871 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0299605 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0293098 |
| RPL28 | ribosomal protein L28 | -0.028568 |
| RPS24 | ribosomal protein S24 | -0.0269428 |
| FTL | ferritin, light polypeptide | -0.0264609 |
| RPL23 | ribosomal protein L23 | -0.0258996 |
| SQSTM1 | sequestosome 1 | -0.0256764 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0247755 |
| RPL31 | ribosomal protein L31 | -0.0245719 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0242454 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0241016 |
| RPS12 | ribosomal protein S12 | -0.0240858 |
| RPS19 | ribosomal protein S19 | -0.0236687 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0236596 |
| RPS8 | ribosomal protein S8 | -0.0234621 |
| RPL36 | ribosomal protein L36 | -0.0234024 |
| RPL35A | ribosomal protein L35a | -0.0221933 |
| RPL26 | ribosomal protein L26 | -0.0220792 |
| CSTB | cystatin B (stefin B) | -0.0219561 |
| RPS27A | ribosomal protein S27a | -0.0219028 |
| RPLP1 | ribosomal protein, large, P1 | -0.0218292 |
| RPL11 | ribosomal protein L11 | -0.021765 |
| RPS13 | ribosomal protein S13 | -0.0215312 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0204909 |
| RPL12 | ribosomal protein L12 | -0.0204662 |
| GOLGA4 | golgin A4 | -0.0202731 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0201365 |
| RPL9 | ribosomal protein L9 | -0.0199277 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0196251 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | -0.0193625 |
| RPS27 | ribosomal protein S27 | -0.018902 |
| RPS23 | ribosomal protein S23 | -0.0185756 |
| RPS17 | ribosomal protein S17 | -0.018336 |
| RPS16 | ribosomal protein S16 | -0.0179904 |
| RPL37 | ribosomal protein L37 | -0.0178326 |
| NAV2 | neuron navigator 2 | -0.017733 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0176131 |
| CD109 | CD109 molecule | -0.0172929 |
| RPS25 | ribosomal protein S25 | -0.0172547 |
| RPS29 | ribosomal protein S29 | -0.0161181 |
| RPS14 | ribosomal protein S14 | -0.0157668 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0154795 |
| S100A11 | S100 calcium binding protein A11 | -0.0153535 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0148571 |
| MNT | MAX network transcriptional repressor | -0.0147513 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0146822 |
| RPS21 | ribosomal protein S21 | -0.0142895 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.0140458 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.0139326 |
| RND3 | Rho family GTPase 3 | -0.0137925 |
| RPL7A | ribosomal protein L7a | -0.0137773 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0137491 |
| RPS15 | ribosomal protein S15 | -0.0135531 |
| RPL34 | ribosomal protein L34 | -0.0133314 |
| RPS20 | ribosomal protein S20 | -0.0130898 |
| RPL38 | ribosomal protein L38 | -0.0130744 |
| ULK1 | unc-51 like autophagy activating kinase 1 | -0.0128511 |
| CTSD | cathepsin D | -0.012769 |
| RPL36A | ribosomal protein L36a | -0.0124607 |
| FOSL1 | FOS-like antigen 1 | -0.0124423 |
| ADM | adrenomedullin | -0.0124118 |
| RPL27 | ribosomal protein L27 | -0.0123784 |
| FAM107B | family with sequence similarity 107, member B | -0.012298 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0121265 |
| RPL27A | ribosomal protein L27a | -0.01205 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0120352 |
| UPP1 | uridine phosphorylase 1 | -0.0120328 |
| RPS11 | ribosomal protein S11 | -0.0119504 |
| CD81 | CD81 molecule | -0.0119279 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.011782 |
| DTNA | dystrobrevin, alpha | -0.0117718 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0117175 |
| RPL5 | ribosomal protein L5 | -0.011615 |
| RPL19 | ribosomal protein L19 | -0.0112821 |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase | -0.0112667 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0110966 |
| RPL35 | ribosomal protein L35 | -0.0110584 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0109948 |
| OCIAD2 | OCIA domain containing 2 | -0.0108772 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0108388 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | -0.010764 |
| IL32 | interleukin 32 | -0.0105192 |
| RACK1 | receptor for activated C kinase 1 | -0.0104659 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0104474 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0102657 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0102509 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0102329 |
| RPL13A | ribosomal protein L13a | -0.010137 |
| GLRX | glutaredoxin (thioltransferase) | -0.0101279 |
