| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | AT7519 perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the AT7519_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MBNL2 | muscleblind-like splicing regulator 2 | 0.130764 |
| B2M | beta-2-microglobulin | 0.123315 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.117623 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.104491 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.100171 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0854494 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0781413 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0692484 |
| NCKAP5 | NCK-associated protein 5 | 0.0657395 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0649637 |
| ITGA6 | integrin, alpha 6 | 0.0641361 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0561084 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0557343 |
| RAD51B | RAD51 paralog B | 0.0528982 |
| LCN2 | lipocalin 2 | 0.0506427 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0487871 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0483479 |
| SPATA13 | spermatogenesis associated 13 | 0.0471374 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0471041 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0468377 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0461225 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0456262 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0439644 |
| MECOM | MDS1 and EVI1 complex locus | 0.0438207 |
| PRKCA | protein kinase C, alpha | 0.0428546 |
| DST | dystonin | 0.0428192 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0422594 |
| CALR | calreticulin | 0.0414589 |
| ATXN1 | ataxin 1 | 0.0414026 |
| MACC1 | metastasis associated in colon cancer 1 | 0.041156 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0403653 |
| ATP10B | ATPase, class V, type 10B | 0.0400444 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0398392 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.0396646 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0392729 |
| TMC5 | transmembrane channel-like 5 | 0.0386986 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0381363 |
| RBM47 | RNA binding motif protein 47 | 0.0377275 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0370209 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0362352 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0360594 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | 0.0351452 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0346912 |
| RNF213 | ring finger protein 213 | 0.0346328 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0344922 |
| FOXP1 | forkhead box P1 | 0.0342877 |
| MX1 | MX dynamin-like GTPase 1 | 0.0340524 |
| DGKH | diacylglycerol kinase, eta | 0.0336668 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0333959 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0333442 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0332049 |
| PTK2 | protein tyrosine kinase 2 | 0.0329578 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0328343 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0327983 |
| CANX | calnexin | 0.0325258 |
| CCNL1 | cyclin L1 | 0.0322984 |
| ZNF292 | zinc finger protein 292 | 0.0321895 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.0320511 |
| UTRN | utrophin | 0.0319028 |
| PADI1 | peptidyl arginine deiminase, type I | 0.031822 |
| CDHR2 | cadherin-related family member 2 | 0.0317111 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0316144 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0315719 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | 0.0309492 |
| KRT8 | keratin 8, type II | 0.0308534 |
| SMAD3 | SMAD family member 3 | 0.0305263 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0303722 |
| XDH | xanthine dehydrogenase | 0.0303721 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0303266 |
| DUSP16 | dual specificity phosphatase 16 | 0.0302921 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0296573 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | 0.0295276 |
| ALPK1 | alpha-kinase 1 | 0.0293611 |
| UBAC2 | UBA domain containing 2 | 0.0292217 |
| ETV6 | ets variant 6 | 0.0290554 |
| LMO7 | LIM domain 7 | 0.0289225 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0287057 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0285452 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0284596 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0284282 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0280906 |
| FNIP1 | folliculin interacting protein 1 | 0.028051 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.0276506 |
| TRERF1 | transcriptional regulating factor 1 | 0.0275185 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0272769 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0272273 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0271905 |
| SYT1 | synaptotagmin I | 0.0270932 |
| MYO10 | myosin X | 0.0270577 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0268386 |
| DSPP | dentin sialophosphoprotein | 0.0267771 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0261859 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0259181 |
| NCALD | neurocalcin delta | 0.0258153 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | 0.0257244 |
| KIF16B | kinesin family member 16B | 0.0257231 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0257074 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0254038 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0252735 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.025258 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.17338 |
| EGR1 | early growth response 1 | -0.0986556 |
| ANXA2 | annexin A2 | -0.0979022 |
| INTS6 | integrator complex subunit 6 | -0.0861459 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0824804 |
| PLSCR2 | phospholipid scramblase 2 | -0.0803601 |
| PTMA | prothymosin, alpha | -0.0760006 |
| PERP | PERP, TP53 apoptosis effector | -0.0757116 |
| RPL35A | ribosomal protein L35a | -0.0644781 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0618945 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0586195 |
| RPL34 | ribosomal protein L34 | -0.0555532 |
| RPS6 | ribosomal protein S6 | -0.0551909 |
| VCL | vinculin | -0.0550443 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.053173 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0508754 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0476841 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0476301 |
| HLA-C | major histocompatibility complex, class I, C | -0.0456306 |
| RPL23 | ribosomal protein L23 | -0.0447265 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.044241 |
| RPLP1 | ribosomal protein, large, P1 | -0.0432892 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.042746 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.042635 |
| EZR | ezrin | -0.0417071 |
| MCL1 | myeloid cell leukemia 1 | -0.041477 |
| LAMA4 | laminin, alpha 4 | -0.0408552 |
| S100A10 | S100 calcium binding protein A10 | -0.0408401 |
| TMSB10 | thymosin beta 10 | -0.0398539 |
| AREG | amphiregulin | -0.0398062 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0390063 |
| HLA-B | major histocompatibility complex, class I, B | -0.0388977 |
| ACTN4 | actinin, alpha 4 | -0.0379457 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0374985 |
| RPLP0 | ribosomal protein, large, P0 | -0.0362721 |
| SQSTM1 | sequestosome 1 | -0.0362648 |
| JUN | jun proto-oncogene | -0.0357681 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0352468 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0345776 |
| NABP1 | nucleic acid binding protein 1 | -0.0342741 |
| HMGB1 | high mobility group box 1 | -0.0338202 |
| ACTG1 | actin gamma 1 | -0.0325563 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0324681 |
| S100A6 | S100 calcium binding protein A6 | -0.0315645 |
| RPL19 | ribosomal protein L19 | -0.0313814 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0312693 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0307851 |
| RPS24 | ribosomal protein S24 | -0.0298385 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0291085 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0287756 |
| S100A11 | S100 calcium binding protein A11 | -0.0287283 |
| PKM | pyruvate kinase, muscle | -0.0285039 |
| RPL12 | ribosomal protein L12 | -0.0283129 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | -0.0276831 |
| KPNB1 | karyopherin (importin) beta 1 | -0.026664 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0265062 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0261019 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0253705 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0252456 |
| RTN4 | reticulon 4 | -0.0250285 |
| KLF6 | Kruppel-like factor 6 | -0.0244798 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0243151 |
| RPL30 | ribosomal protein L30 | -0.0240847 |
| FOXO3 | forkhead box O3 | -0.0239349 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.02388 |
| IER3 | immediate early response 3 | -0.0236507 |
| SERINC5 | serine incorporator 5 | -0.0234293 |
| RPS27 | ribosomal protein S27 | -0.0231258 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0231032 |
| USP53 | ubiquitin specific peptidase 53 | -0.0223979 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0221301 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0220918 |
| RPS19 | ribosomal protein S19 | -0.0220588 |
| RPS25 | ribosomal protein S25 | -0.0220415 |
| POU2F2 | POU class 2 homeobox 2 | -0.0219899 |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | -0.0217195 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0215448 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0215218 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0210291 |
| SLC25A25 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 | -0.0210213 |
| UBAP2 | ubiquitin associated protein 2 | -0.0210156 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0208107 |
| RPLP2 | ribosomal protein, large, P2 | -0.0208091 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0207244 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0206677 |
| JUP | junction plakoglobin | -0.0206282 |
| HLA-A | major histocompatibility complex, class I, A | -0.0204256 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0203861 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0203551 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0202643 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | -0.020258 |
| GLO1 | glyoxalase I | -0.0200728 |
| RPS11 | ribosomal protein S11 | -0.0197696 |
| LIMA1 | LIM domain and actin binding 1 | -0.0195001 |
| RPL35 | ribosomal protein L35 | -0.0193649 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0193383 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0193169 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0193048 |
| RRBP1 | ribosome binding protein 1 | -0.0192875 |
| STX5 | syntaxin 5 | -0.0192705 |
