| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | AT7519 perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the AT7519_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.133728 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.066683 |
| TGM2 | transglutaminase 2 | 0.0633448 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0566747 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0560601 |
| MYOF | myoferlin | 0.0523955 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0515203 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0485473 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0474058 |
| MEF2A | myocyte enhancer factor 2A | 0.0472559 |
| CD44 | CD44 molecule (Indian blood group) | 0.0462278 |
| RAI14 | retinoic acid induced 14 | 0.0451889 |
| NDRG1 | N-myc downstream regulated 1 | 0.0451101 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0436445 |
| ANXA1 | annexin A1 | 0.0397551 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0389418 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.037238 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0366932 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0364116 |
| DOK5 | docking protein 5 | 0.0358545 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0333588 |
| MSN | moesin | 0.0330957 |
| TXNIP | thioredoxin interacting protein | 0.0329558 |
| ZNF292 | zinc finger protein 292 | 0.0323212 |
| LAMA5 | laminin, alpha 5 | 0.0313454 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0286069 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0283574 |
| ARRDC3 | arrestin domain containing 3 | 0.0283199 |
| NAV2 | neuron navigator 2 | 0.0277128 |
| TPM3 | tropomyosin 3 | 0.0276713 |
| FN1 | fibronectin 1 | 0.0275344 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0274565 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0269707 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0262874 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0258335 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0256091 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0254794 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0254237 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0251947 |
| FRMD6 | FERM domain containing 6 | 0.0251662 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0248165 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0247105 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0245692 |
| GOLGB1 | golgin B1 | 0.0241985 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0240165 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0239636 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0236536 |
| ASPH | aspartate beta-hydroxylase | 0.023633 |
| ANKRD28 | ankyrin repeat domain 28 | 0.023416 |
| IFI44L | interferon-induced protein 44-like | 0.0232763 |
| QKI | QKI, KH domain containing, RNA binding | 0.0221296 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0220179 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0219687 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0218868 |
| ZNF395 | zinc finger protein 395 | 0.0218445 |
| AOPEP | aminopeptidase O (putative) | 0.0216886 |
| VEGFA | vascular endothelial growth factor A | 0.0216773 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0211543 |
| FOXP1 | forkhead box P1 | 0.0211315 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.020983 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0207588 |
| SULF2 | sulfatase 2 | 0.0203586 |
| SIK3 | SIK family kinase 3 | 0.020237 |
| BARX2 | BARX homeobox 2 | 0.0201508 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0200811 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0200511 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0199268 |
| PLS3 | plastin 3 | 0.0198725 |
| EFNA5 | ephrin-A5 | 0.0197979 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0195539 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0194335 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0193164 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0185173 |
| PLEC | plectin | 0.0184677 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0179966 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0179188 |
| ANO6 | anoctamin 6 | 0.0179141 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.01791 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0178784 |
| ATP9A | ATPase, class II, type 9A | 0.0176364 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0175688 |
| JAG1 | jagged 1 | 0.0175207 |
| BCR | breakpoint cluster region | 0.0174636 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0168645 |
| RAD51B | RAD51 paralog B | 0.0167194 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0166819 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0164995 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0164357 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.016408 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0163945 |
| STC1 | stanniocalcin 1 | 0.0160617 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0158188 |
| PHF3 | PHD finger protein 3 | 0.0156594 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0156344 |
| RNF217 | ring finger protein 217 | 0.0154744 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0153616 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0150294 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.0149141 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0148995 |
| FAM107B | family with sequence similarity 107, member B | 0.0148564 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.209731 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.194452 |
| FLNB | filamin B, beta | -0.181397 |
| TMSB10 | thymosin beta 10 | -0.110601 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.101439 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0916588 |
| RPS21 | ribosomal protein S21 | -0.0843585 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0789492 |
| PTMA | prothymosin, alpha | -0.0756032 |
| SULF1 | sulfatase 1 | -0.0705831 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0679444 |
| RPLP2 | ribosomal protein, large, P2 | -0.0587366 |
| S100A10 | S100 calcium binding protein A10 | -0.0573827 |
| KRT17 | keratin 17, type I | -0.0549887 |
| BCL2L1 | BCL2-like 1 | -0.049743 |
| HM13 | histocompatibility (minor) 13 | -0.0493859 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0493661 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.04906 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0462558 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0456033 |
| ITGA6 | integrin, alpha 6 | -0.04501 |
| MECOM | MDS1 and EVI1 complex locus | -0.0413108 |
| RPS13 | ribosomal protein S13 | -0.0412478 |
| MT2A | metallothionein 2A | -0.039604 |
| SQLE | squalene epoxidase | -0.0388126 |
| HLA-B | major histocompatibility complex, class I, B | -0.0384515 |
| GNAS | GNAS complex locus | -0.0377928 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0365676 |
| S100A11 | S100 calcium binding protein A11 | -0.035723 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.035011 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0342354 |
| EXOC6B | exocyst complex component 6B | -0.0336653 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0332228 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0329089 |
| RPL37A | ribosomal protein L37a | -0.0326933 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0326147 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0324346 |
| DOCK5 | dedicator of cytokinesis 5 | -0.032123 |
| S100A9 | S100 calcium binding protein A9 | -0.0319914 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0318485 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0314032 |
| MYL12B | myosin, light chain 12B, regulatory | -0.031339 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0310748 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0309445 |
| RPS29 | ribosomal protein S29 | -0.0300087 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0297414 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.029251 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0290729 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0290012 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0289332 |
| PODXL | podocalyxin-like | -0.028664 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0284913 |
| TPM4 | tropomyosin 4 | -0.028462 |
| TXNRD1 | thioredoxin reductase 1 | -0.0283885 |
| NEK7 | NIMA-related kinase 7 | -0.0281312 |
| THBD | thrombomodulin | -0.0281206 |
| NRCAM | neuronal cell adhesion molecule | -0.0280982 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0280959 |
| CAVIN1 | caveolae associated protein 1 | -0.0279533 |
| RPS24 | ribosomal protein S24 | -0.027934 |
| KRT6A | keratin 6A, type II | -0.027921 |
| LMNA | lamin A/C | -0.0278825 |
| SYPL1 | synaptophysin-like 1 | -0.0277842 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0276534 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0275959 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0274875 |
| RPL11 | ribosomal protein L11 | -0.0274485 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0271189 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0270521 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0270442 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0270136 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0267172 |
| TMEM41B | transmembrane protein 41B | -0.0263805 |
| FOXO1 | forkhead box O1 | -0.0262831 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.026035 |
| S100A2 | S100 calcium binding protein A2 | -0.0257642 |
| RPS19 | ribosomal protein S19 | -0.025729 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0256849 |
| PALLD | palladin, cytoskeletal associated protein | -0.0252037 |
| WASF2 | WAS protein family, member 2 | -0.0249271 |
| CD59 | CD59 molecule, complement regulatory protein | -0.024807 |
| GOLGA4 | golgin A4 | -0.0247167 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0247088 |
| RTN4 | reticulon 4 | -0.0246009 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0245776 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0245258 |
| ANXA2 | annexin A2 | -0.0245237 |
| RPL31 | ribosomal protein L31 | -0.0243737 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.0238504 |
| DUSP5 | dual specificity phosphatase 5 | -0.0237849 |
| RPS27A | ribosomal protein S27a | -0.0232515 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0231411 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0231163 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0230695 |
| ACTN4 | actinin, alpha 4 | -0.0228903 |
| APP | amyloid beta (A4) precursor protein | -0.0226052 |
| TMEM263 | transmembrane protein 263 | -0.0222635 |
| EHBP1 | EH domain binding protein 1 | -0.0222267 |
| C4BPB | complement component 4 binding protein, beta | -0.0216317 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0216062 |
