| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | AT7519 perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the AT7519_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FGFR2 | fibroblast growth factor receptor 2 | 0.265888 |
| B2M | beta-2-microglobulin | 0.0942877 |
| POTEF | POTE ankyrin domain family, member F | 0.0925762 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0798118 |
| TMC5 | transmembrane channel-like 5 | 0.0600363 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0599583 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0563933 |
| AGR3 | anterior gradient 3 | 0.055914 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0526054 |
| DSPP | dentin sialophosphoprotein | 0.0500629 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0483693 |
| KRT8 | keratin 8, type II | 0.0476173 |
| KRT18 | keratin 18, type I | 0.0457519 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0449156 |
| CALR | calreticulin | 0.0447863 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0439279 |
| MYOF | myoferlin | 0.0429416 |
| H1-0 | H1.0 linker histone | 0.0374232 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0373147 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0372627 |
| MGAM2 | maltase-glucoamylase 2 (putative) | 0.0360674 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.034894 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0343889 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0335797 |
| LYZ | lysozyme | 0.0335766 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0327796 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0323525 |
| TXNIP | thioredoxin interacting protein | 0.031483 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0314732 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0306662 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0304181 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0303741 |
| RNF213 | ring finger protein 213 | 0.0289842 |
| SEPTIN9 | septin 9 | 0.0287178 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0281252 |
| ZNF292 | zinc finger protein 292 | 0.0280913 |
| PLS1 | plastin 1 | 0.0279422 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.027937 |
| ANLN | anillin, actin binding protein | 0.027932 |
| HYOU1 | hypoxia up-regulated 1 | 0.0278608 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.027545 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0274907 |
| MKI67 | marker of proliferation Ki-67 | 0.0272778 |
| TXNRD1 | thioredoxin reductase 1 | 0.0267468 |
| LIMA1 | LIM domain and actin binding 1 | 0.0267364 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0265319 |
| CD2AP | CD2-associated protein | 0.0255538 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0250204 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.024665 |
| VEGFA | vascular endothelial growth factor A | 0.0244428 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0244305 |
| AOPEP | aminopeptidase O (putative) | 0.0241549 |
| MUC1 | mucin 1, cell surface associated | 0.024044 |
| HELZ | helicase with zinc finger | 0.023958 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0239572 |
| GSTP1 | glutathione S-transferase pi 1 | 0.0237985 |
| TRAK1 | trafficking protein, kinesin binding 1 | 0.0233131 |
| PKM | pyruvate kinase, muscle | 0.0232696 |
| PCBP2 | poly(rC) binding protein 2 | 0.0230665 |
| TMF1 | TATA element modulatory factor 1 | 0.0225641 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0222836 |
| PCM1 | pericentriolar material 1 | 0.0222368 |
| SHROOM3 | shroom family member 3 | 0.0221149 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0220694 |
| CBX3 | chromobox homolog 3 | 0.0220647 |
| FAT1 | FAT atypical cadherin 1 | 0.0219414 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0217369 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0213647 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0213067 |
| GDA | guanine deaminase | 0.0211371 |
| C12ORF75 | chromosome 12 open reading frame 75 | 0.0210786 |
| RBM47 | RNA binding motif protein 47 | 0.0210523 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0210487 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.020935 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0208477 |
| CLINT1 | clathrin interactor 1 | 0.0208149 |
| CLDN7 | claudin 7 | 0.0206409 |
| CLTC | clathrin, heavy chain (Hc) | 0.0205923 |
| FAM13A | family with sequence similarity 13, member A | 0.0205374 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | 0.0204467 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0204457 |
| GOLGA4 | golgin A4 | 0.020346 |
| XPO1 | exportin 1 | 0.0203412 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0201425 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0200832 |
| LMNA | lamin A/C | 0.0198869 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0198124 |
| MYADM | myeloid-associated differentiation marker | 0.0196893 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0195982 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0191963 |
| SRP54 | signal recognition particle 54kDa | 0.0189852 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.018703 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0186939 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0185527 |
| DSG2 | desmoglein 2 | 0.0183311 |
| RABGAP1 | RAB GTPase activating protein 1 | 0.0183156 |
| CENPF | centromere protein F, 350/400kDa | 0.0183089 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0181871 |
| CD164 | CD164 molecule, sialomucin | 0.01801 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0178656 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.201651 |
| NPSR1 | neuropeptide S receptor 1 | -0.177922 |
| TMSB10 | thymosin beta 10 | -0.125968 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.111773 |
| RPL35A | ribosomal protein L35a | -0.0745053 |
| RPS25 | ribosomal protein S25 | -0.0740393 |
| FLNB | filamin B, beta | -0.0724864 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0690983 |
| RPS6 | ribosomal protein S6 | -0.0667033 |
| AREG | amphiregulin | -0.0662016 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0643723 |
| FTL | ferritin, light polypeptide | -0.0613572 |
| RPS24 | ribosomal protein S24 | -0.0578073 |
| RPL23 | ribosomal protein L23 | -0.0559023 |
| RPS3 | ribosomal protein S3 | -0.0557081 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0551651 |
| KLHL29 | kelch-like family member 29 | -0.053857 |
| ANXA2 | annexin A2 | -0.0537904 |
| RPL37A | ribosomal protein L37a | -0.0507257 |
| ACTG1 | actin gamma 1 | -0.0506593 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0494419 |
| RPL26 | ribosomal protein L26 | -0.0484419 |
| S100P | S100 calcium binding protein P | -0.0478555 |
| EHBP1 | EH domain binding protein 1 | -0.0474088 |
| RPS8 | ribosomal protein S8 | -0.0474058 |
| INTS6 | integrator complex subunit 6 | -0.046084 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0448842 |
| RPS12 | ribosomal protein S12 | -0.0420359 |
| RPS29 | ribosomal protein S29 | -0.0409181 |
| RPS27A | ribosomal protein S27a | -0.0406192 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0401858 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0377436 |
| EGR1 | early growth response 1 | -0.037602 |
| VCL | vinculin | -0.0374523 |
| RPL9 | ribosomal protein L9 | -0.0373747 |
| RPS17 | ribosomal protein S17 | -0.0366596 |
| LAMB3 | laminin, beta 3 | -0.035961 |
| RPL38 | ribosomal protein L38 | -0.0352411 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0347552 |
| FBXO11 | F-box protein 11 | -0.0343832 |
| RPLP1 | ribosomal protein, large, P1 | -0.0337911 |
| PTMA | prothymosin, alpha | -0.0328917 |
| RPL11 | ribosomal protein L11 | -0.0328155 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0326861 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0325843 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0325742 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0322636 |
| RPS21 | ribosomal protein S21 | -0.0319901 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.031892 |
| RPL31 | ribosomal protein L31 | -0.0317218 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0313556 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0312883 |
| RPL34 | ribosomal protein L34 | -0.0309629 |
| RPL13A | ribosomal protein L13a | -0.0304077 |
| HM13 | histocompatibility (minor) 13 | -0.0303765 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0298808 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0298691 |
| RPL27 | ribosomal protein L27 | -0.0297687 |
| FRMD5 | FERM domain containing 5 | -0.0297542 |
| FOSL1 | FOS-like antigen 1 | -0.0292981 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0292281 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0290921 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.028886 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0288742 |
| CCND1 | cyclin D1 | -0.0288628 |
| RPL36A | ribosomal protein L36a | -0.0286208 |
| HMGA1 | high mobility group AT-hook 1 | -0.0285587 |
| FOXO3 | forkhead box O3 | -0.0285309 |
| RPL19 | ribosomal protein L19 | -0.0278301 |
| MCL1 | myeloid cell leukemia 1 | -0.0275303 |
| RPL5 | ribosomal protein L5 | -0.0273799 |
| RPS23 | ribosomal protein S23 | -0.0270392 |
| HLA-B | major histocompatibility complex, class I, B | -0.0270194 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0267354 |
| RPS16 | ribosomal protein S16 | -0.0266206 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.026407 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0262282 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0260336 |
| S100A10 | S100 calcium binding protein A10 | -0.0260006 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0257444 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0255779 |
| FUS | FUS RNA binding protein | -0.0250261 |
| TFRC | transferrin receptor | -0.0249394 |
| RPS11 | ribosomal protein S11 | -0.0248341 |
| LCN2 | lipocalin 2 | -0.0247876 |
| TPM4 | tropomyosin 4 | -0.0246188 |
| FDPS | farnesyl diphosphate synthase | -0.0245401 |
| CUX1 | cut-like homeobox 1 | -0.0244059 |
| IER3 | immediate early response 3 | -0.0242875 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.024244 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.024227 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -0.0239423 |
| RPS10 | ribosomal protein S10 | -0.0234824 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0234093 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0230938 |
| TJP1 | tight junction protein 1 | -0.0230754 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0228132 |
| RPS13 | ribosomal protein S13 | -0.0227672 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0227633 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0225889 |
