| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | AT7519 perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the AT7519_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| POTEF | POTE ankyrin domain family, member F | 0.144156 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0711906 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0705655 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0702255 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.066694 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0610495 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0599495 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0545761 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0534401 |
| FMNL2 | formin-like 2 | 0.050801 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0469587 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0450774 |
| RPS12 | ribosomal protein S12 | 0.0436087 |
| FTL | ferritin, light polypeptide | 0.043538 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.042637 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0426206 |
| RPL37A | ribosomal protein L37a | 0.0396098 |
| PCDH1 | protocadherin 1 | 0.0389961 |
| DNER | delta/notch-like EGF repeat containing | 0.0379722 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0362154 |
| B2M | beta-2-microglobulin | 0.0360221 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0358156 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0353949 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0351024 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0349203 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0340767 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0329795 |
| CALR | calreticulin | 0.0326258 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.032352 |
| VEGFA | vascular endothelial growth factor A | 0.0318053 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0317127 |
| RPS8 | ribosomal protein S8 | 0.031664 |
| HDAC9 | histone deacetylase 9 | 0.0312338 |
| MYOF | myoferlin | 0.0310468 |
| INTS6 | integrator complex subunit 6 | 0.0310067 |
| LOXL2 | lysyl oxidase-like 2 | 0.0304709 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0302235 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0297995 |
| PODXL | podocalyxin-like | 0.0293471 |
| RPS3 | ribosomal protein S3 | 0.0288035 |
| LYST | lysosomal trafficking regulator | 0.0287899 |
| PCBP2 | poly(rC) binding protein 2 | 0.0284052 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0280312 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0278648 |
| NDRG1 | N-myc downstream regulated 1 | 0.0276157 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0272611 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0269944 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0267781 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0260638 |
| CADM2 | cell adhesion molecule 2 | 0.02539 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0253564 |
| EGFR | epidermal growth factor receptor | 0.0248016 |
| RPL31 | ribosomal protein L31 | 0.0247929 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0246059 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0245592 |
| CAPRIN2 | caprin family member 2 | 0.0239411 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0237258 |
| PLIN2 | perilipin 2 | 0.0237198 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0232769 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0230349 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0226802 |
| EPHA4 | EPH receptor A4 | 0.022586 |
| PLK2 | polo-like kinase 2 | 0.0225524 |
| MSN | moesin | 0.0224517 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0221499 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.02199 |
| EFNA5 | ephrin-A5 | 0.0219406 |
| RPS10 | ribosomal protein S10 | 0.0219342 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0216745 |
| TNS3 | tensin 3 | 0.021502 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0213729 |
| TXNIP | thioredoxin interacting protein | 0.0210813 |
| PKM | pyruvate kinase, muscle | 0.0209066 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0207291 |
| RCOR1 | REST corepressor 1 | 0.0207159 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0206759 |
| TGM2 | transglutaminase 2 | 0.0203103 |
| FNIP1 | folliculin interacting protein 1 | 0.0200453 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | 0.0200114 |
| CUX1 | cut-like homeobox 1 | 0.0199629 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0199382 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0199166 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0197971 |
| UBAP2 | ubiquitin associated protein 2 | 0.0195119 |
| CTBP2 | C-terminal binding protein 2 | 0.0192524 |
| HDGF | hepatoma-derived growth factor | 0.0192353 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0190966 |
| AEBP2 | AE binding protein 2 | 0.0190881 |
| DENND1A | DENN/MADD domain containing 1A | 0.018954 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0189469 |
| RPL37 | ribosomal protein L37 | 0.0185864 |
| DOCK11 | dedicator of cytokinesis 11 | 0.0184829 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | 0.0184068 |
| NAV2 | neuron navigator 2 | 0.018362 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0183126 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0183099 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0183023 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0182836 |
| HLA-A | major histocompatibility complex, class I, A | 0.0182316 |
| ATXN2 | ataxin 2 | 0.0181007 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.172975 |
| TXNRD1 | thioredoxin reductase 1 | -0.12909 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.104331 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0963447 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0876772 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0845339 |
| TMSB10 | thymosin beta 10 | -0.0810106 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0659852 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0628495 |
| RIGI | RNA sensor RIG-I | -0.0622738 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0601448 |
| AHNAK | AHNAK nucleoprotein | -0.0593488 |
| EZR | ezrin | -0.0506924 |
| MKI67 | marker of proliferation Ki-67 | -0.0492012 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0459088 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0445162 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0432185 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0416715 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0404492 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0396288 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0386427 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0380298 |
| TMEM41B | transmembrane protein 41B | -0.0369185 |
| SPAG9 | sperm associated antigen 9 | -0.0360529 |
| ZNF217 | zinc finger protein 217 | -0.0348079 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0337004 |
| RGS4 | regulator of G-protein signaling 4 | -0.0329162 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0327235 |
| RTN4 | reticulon 4 | -0.032676 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.032389 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0313296 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0312193 |
| CENPF | centromere protein F, 350/400kDa | -0.0302145 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0296898 |
| BMERB1 | bMERB domain containing 1 | -0.0296427 |
| EMP1 | epithelial membrane protein 1 | -0.0294886 |
| KLF6 | Kruppel-like factor 6 | -0.0292337 |
| PLSCR1 | phospholipid scramblase 1 | -0.0291095 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0290937 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0288639 |
| RAI1 | retinoic acid induced 1 | -0.0288603 |
| PGK1 | phosphoglycerate kinase 1 | -0.0285632 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0283889 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0281764 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0274927 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0273991 |
| ANLN | anillin, actin binding protein | -0.0273864 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0271613 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0271095 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0269375 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0269368 |
| NF1 | neurofibromin 1 | -0.0269187 |
| SRGN | serglycin | -0.0266746 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0264922 |
| H1-0 | H1.0 linker histone | -0.0261722 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0261301 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0258861 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0254003 |
| CD44 | CD44 molecule (Indian blood group) | -0.0249697 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0248466 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0244104 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0242922 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0241747 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0240575 |
| USP34 | ubiquitin specific peptidase 34 | -0.0239104 |
| TUBB | tubulin, beta class I | -0.0238462 |
| DIAPH3 | diaphanous-related formin 3 | -0.0237819 |
| OSMR | oncostatin M receptor | -0.0237728 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0236166 |
| EGR1 | early growth response 1 | -0.0235563 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0233146 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0232767 |
| JMJD1C | jumonji domain containing 1C | -0.0231781 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0229342 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0229009 |
| YBX3 | Y box binding protein 3 | -0.0227143 |
| XPO1 | exportin 1 | -0.0226922 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0226159 |
| ARF1 | ADP-ribosylation factor 1 | -0.0224692 |
| HMGB2 | high mobility group box 2 | -0.0224216 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0223562 |
| OGA | O-GlcNAcase | -0.0222482 |
| VIM | vimentin | -0.0221988 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0220976 |
| CDCP1 | CUB domain containing protein 1 | -0.0220665 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0220568 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0220541 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | -0.0220206 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0219458 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0216745 |
| FERMT1 | fermitin family member 1 | -0.0216413 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0215337 |
| XPO7 | exportin 7 | -0.0215019 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0214278 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0213305 |
| SEPTIN7 | septin 7 | -0.0213054 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0212081 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0211746 |
| RBM39 | RNA binding motif protein 39 | -0.0211553 |
| CUL1 | cullin 1 | -0.0210273 |
