| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | AT7519 perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the AT7519_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.171181 |
| CD44 | CD44 molecule (Indian blood group) | 0.16059 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.124699 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.109529 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.103904 |
| FN1 | fibronectin 1 | 0.0941482 |
| SMAD3 | SMAD family member 3 | 0.0924416 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0810406 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.077347 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0756411 |
| B2M | beta-2-microglobulin | 0.0721095 |
| PCBP2 | poly(rC) binding protein 2 | 0.0685653 |
| TGM2 | transglutaminase 2 | 0.0656633 |
| NDRG1 | N-myc downstream regulated 1 | 0.0613237 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0594724 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0591936 |
| VIM | vimentin | 0.0590551 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0576202 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0576049 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0569494 |
| DST | dystonin | 0.0566586 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0553871 |
| CA12 | carbonic anhydrase XII | 0.055306 |
| RAD51B | RAD51 paralog B | 0.0548371 |
| POTEF | POTE ankyrin domain family, member F | 0.0537722 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0531448 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0526082 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0523611 |
| MAP1B | microtubule-associated protein 1B | 0.0517928 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0513271 |
| VEGFA | vascular endothelial growth factor A | 0.0512985 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0500923 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0496062 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0467973 |
| CDCP1 | CUB domain containing protein 1 | 0.0464062 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0459677 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0457206 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0445142 |
| PKM | pyruvate kinase, muscle | 0.0443357 |
| ASPH | aspartate beta-hydroxylase | 0.0429431 |
| LOXL2 | lysyl oxidase-like 2 | 0.042847 |
| TNNC1 | troponin C type 1 (slow) | 0.0415945 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0415351 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0414808 |
| VMP1 | vacuole membrane protein 1 | 0.0409528 |
| ECE1 | endothelin converting enzyme 1 | 0.0409216 |
| GPC6 | glypican 6 | 0.0406393 |
| SYT1 | synaptotagmin I | 0.0403597 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0392538 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0386043 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0383465 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0382355 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0378042 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0370119 |
| NAV2 | neuron navigator 2 | 0.0369503 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0356198 |
| ANXA2 | annexin A2 | 0.0355734 |
| EGR1 | early growth response 1 | 0.0355182 |
| TBC1D5 | TBC1 domain family, member 5 | 0.035162 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0348429 |
| MYO10 | myosin X | 0.0346819 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0345231 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0343709 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0343666 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0336531 |
| BRD2 | bromodomain containing 2 | 0.0336424 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0332191 |
| ENO1 | enolase 1, (alpha) | 0.0332014 |
| SYAP1 | synapse associated protein 1 | 0.0331303 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0328167 |
| NTN4 | netrin 4 | 0.0326555 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0324984 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0324279 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0322507 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0317923 |
| OPTN | optineurin | 0.0316884 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0310072 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0309761 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0309339 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0306978 |
| RUNX1 | runt-related transcription factor 1 | 0.0304265 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0304118 |
| MYO1E | myosin IE | 0.0300239 |
| HDAC9 | histone deacetylase 9 | 0.0298608 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0296854 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0296029 |
| SIK3 | SIK family kinase 3 | 0.0294338 |
| SFTPA2 | surfactant protein A2 | 0.0293843 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.029292 |
| EFNA5 | ephrin-A5 | 0.0292364 |
| STK38L | serine/threonine kinase 38 like | 0.028532 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0284645 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0283473 |
| FLNB | filamin B, beta | 0.0280221 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.027925 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0278926 |
| SYNJ2 | synaptojanin 2 | 0.027756 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0277401 |
| FAM107B | family with sequence similarity 107, member B | 0.027405 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0271405 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.162852 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.128389 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.101419 |
| TMSB10 | thymosin beta 10 | -0.0986837 |
| MTSS1 | metastasis suppressor 1 | -0.0864231 |
| NRG1 | neuregulin 1 | -0.0850236 |
| CDH13 | cadherin 13 | -0.0663676 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0663553 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0644782 |
| PTMA | prothymosin, alpha | -0.0573773 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0449874 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0434977 |
| RPL35A | ribosomal protein L35a | -0.0364362 |
| IL1B | interleukin 1, beta | -0.0354452 |
| CDK14 | cyclin-dependent kinase 14 | -0.0351185 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0333898 |
| FDPS | farnesyl diphosphate synthase | -0.032462 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0320414 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0317656 |
| DNER | delta/notch-like EGF repeat containing | -0.031588 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0313605 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0311229 |
| ANXA10 | annexin A10 | -0.0289365 |
| DTNA | dystrobrevin, alpha | -0.0283509 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0276104 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.027328 |
| NUMB | numb homolog (Drosophila) | -0.0268822 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.02671 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.026465 |
| RBM39 | RNA binding motif protein 39 | -0.0259612 |
| SH3RF3 | SH3 domain containing ring finger 3 | -0.0255606 |
| NLK | nemo-like kinase | -0.0249437 |
| PRRX1 | paired related homeobox 1 | -0.0246273 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0246198 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0245372 |
| FTL | ferritin, light polypeptide | -0.0244275 |
| RPS24 | ribosomal protein S24 | -0.0242879 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0240345 |
| FAM20C | family with sequence similarity 20, member C | -0.0236909 |
| STC1 | stanniocalcin 1 | -0.0235316 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0235312 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0234879 |
| PYGL | phosphorylase, glycogen, liver | -0.0231018 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0230392 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0229113 |
| THBD | thrombomodulin | -0.0228891 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0227527 |
| G0S2 | G0/G1 switch 2 | -0.022476 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0223291 |
| MT2A | metallothionein 2A | -0.0222764 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0221307 |
| MEF2A | myocyte enhancer factor 2A | -0.0216998 |
| INSIG1 | insulin induced gene 1 | -0.0210099 |
| IER3 | immediate early response 3 | -0.0209207 |
| TMEM263 | transmembrane protein 263 | -0.0208883 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0208465 |
| RPL38 | ribosomal protein L38 | -0.0206207 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0205502 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0200052 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0198353 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0192074 |
| CLMP | CXADR-like membrane protein | -0.0191261 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0190445 |
| NHSL1 | NHS-like 1 | -0.0189486 |
| FBN1 | fibrillin 1 | -0.0188393 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0186452 |
| CP | ceruloplasmin (ferroxidase) | -0.0183039 |
| OXSR1 | oxidative stress responsive 1 | -0.0182487 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0179565 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0177258 |
| DENND1A | DENN/MADD domain containing 1A | -0.0176243 |
| FRMD4A | FERM domain containing 4A | -0.0174788 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 | -0.0172833 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0168757 |
| MECOM | MDS1 and EVI1 complex locus | -0.0164311 |
| RPS29 | ribosomal protein S29 | -0.0162337 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0162009 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0161784 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0158829 |
| PPP3CC | protein phosphatase 3, catalytic subunit, gamma isozyme | -0.0158247 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0157909 |
| SNX14 | sorting nexin 14 | -0.0156031 |
| WDR45B | WD repeat domain 45B | -0.0154993 |
| GNAS | GNAS complex locus | -0.0153868 |
| TMEM165 | transmembrane protein 165 | -0.0153158 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0152855 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.0152159 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0151953 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.0148403 |
| RPL31 | ribosomal protein L31 | -0.0148083 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0147816 |
| NRCAM | neuronal cell adhesion molecule | -0.0145745 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -0.0145167 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0143831 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0143801 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0143714 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0143627 |
| PCNX4 | pecanex 4 | -0.0143548 |
| EREG | epiregulin | -0.0142465 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0141428 |
