| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | AT7519 perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the AT7519_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.256459 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.139162 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.136439 |
| GLIS3 | GLIS family zinc finger 3 | 0.134573 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.131796 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.130374 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.124967 |
| CD44 | CD44 molecule (Indian blood group) | 0.111019 |
| COL6A3 | collagen, type VI, alpha 3 | 0.108311 |
| HMGA2 | high mobility group AT-hook 2 | 0.10758 |
| B2M | beta-2-microglobulin | 0.094143 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0935537 |
| HDAC9 | histone deacetylase 9 | 0.0920833 |
| LDHA | lactate dehydrogenase A | 0.0881988 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0865197 |
| CALR | calreticulin | 0.0786455 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0733894 |
| CDH13 | cadherin 13 | 0.0705047 |
| FTL | ferritin, light polypeptide | 0.0703286 |
| HLA-B | major histocompatibility complex, class I, B | 0.0698881 |
| FN1 | fibronectin 1 | 0.0695555 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0670924 |
| VEGFA | vascular endothelial growth factor A | 0.0662522 |
| VCAN | versican | 0.066091 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0652781 |
| HLA-E | major histocompatibility complex, class I, E | 0.0640753 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.064004 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0634134 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0630632 |
| AHNAK | AHNAK nucleoprotein | 0.0626034 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0612896 |
| PGK1 | phosphoglycerate kinase 1 | 0.0601708 |
| COL5A1 | collagen, type V, alpha 1 | 0.0594029 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0582255 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0579924 |
| IER3 | immediate early response 3 | 0.0575684 |
| ASPH | aspartate beta-hydroxylase | 0.0567945 |
| HLA-A | major histocompatibility complex, class I, A | 0.0549881 |
| PLIN2 | perilipin 2 | 0.05323 |
| SFTPA2 | surfactant protein A2 | 0.052595 |
| RND3 | Rho family GTPase 3 | 0.0520007 |
| SQSTM1 | sequestosome 1 | 0.0511563 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0508358 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0506603 |
| ENO1 | enolase 1, (alpha) | 0.0473203 |
| ATXN1 | ataxin 1 | 0.0450156 |
| CANX | calnexin | 0.0448885 |
| RNF213 | ring finger protein 213 | 0.0441017 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0434104 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0434097 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0426315 |
| INTS6 | integrator complex subunit 6 | 0.041869 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0418613 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.041381 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0407428 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0404334 |
| TMSB4X | thymosin beta 4, X-linked | 0.0404048 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.040101 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0399917 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0396695 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0387621 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0386691 |
| BICC1 | BicC family RNA binding protein 1 | 0.0381794 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0373101 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0371893 |
| NAV1 | neuron navigator 1 | 0.0367015 |
| SFRP1 | secreted frizzled-related protein 1 | 0.0361901 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0357867 |
| RPS4X | ribosomal protein S4, X-linked | 0.0357382 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0352441 |
| VCL | vinculin | 0.0347227 |
| CTSB | cathepsin B | 0.033769 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0332137 |
| DIAPH2 | diaphanous-related formin 2 | 0.0330786 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0327555 |
| EGFR | epidermal growth factor receptor | 0.0327288 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0325599 |
| EGR1 | early growth response 1 | 0.0324167 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0322865 |
| TMEM132D | transmembrane protein 132D | 0.0317395 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0317108 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0313933 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0312755 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0306633 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.0303202 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0299331 |
| FAM20C | family with sequence similarity 20, member C | 0.029916 |
| EFNA5 | ephrin-A5 | 0.0298082 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0297986 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0297936 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0294659 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.029142 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0289416 |
| NDRG1 | N-myc downstream regulated 1 | 0.0289392 |
| FBXO32 | F-box protein 32 | 0.0286219 |
| INHBA | inhibin, beta A | 0.028525 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0285062 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0281347 |
| TRIM55 | tripartite motif containing 55 | 0.0278967 |
| ACTG1 | actin gamma 1 | 0.0278659 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.185411 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0863058 |
| SPAG9 | sperm associated antigen 9 | -0.0749543 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.065627 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.064708 |
| NAV2 | neuron navigator 2 | -0.0643784 |
| MKI67 | marker of proliferation Ki-67 | -0.0601655 |
| RTN4 | reticulon 4 | -0.0548539 |
| CENPF | centromere protein F, 350/400kDa | -0.0534605 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0518842 |
| RPS2 | ribosomal protein S2 | -0.0470294 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0464153 |
| ANLN | anillin, actin binding protein | -0.0451021 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0438945 |
| OGA | O-GlcNAcase | -0.0413274 |
| MT2A | metallothionein 2A | -0.0403229 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0383131 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0378455 |
| ARRDC3 | arrestin domain containing 3 | -0.0368412 |
| MSN | moesin | -0.0364869 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0364562 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0345272 |
| KIF4A | kinesin family member 4A | -0.0344351 |
| ZNF292 | zinc finger protein 292 | -0.0343071 |
| SBF2 | SET binding factor 2 | -0.0335101 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0334676 |
| DUSP5 | dual specificity phosphatase 5 | -0.0330358 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0319131 |
| TPX2 | TPX2, microtubule-associated | -0.0317054 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0316487 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0308456 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0305253 |
| AFDN | afadin, adherens junction formation factor | -0.0303332 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0301812 |
| PHIP | pleckstrin homology domain interacting protein | -0.0290617 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0290314 |
| GOLGA4 | golgin A4 | -0.0286189 |
| CDCP1 | CUB domain containing protein 1 | -0.0283895 |
| CCNL1 | cyclin L1 | -0.0282948 |
| TMEM41B | transmembrane protein 41B | -0.0279538 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0277765 |
| RBM39 | RNA binding motif protein 39 | -0.0268994 |
| XPO1 | exportin 1 | -0.0262924 |
| JMJD1C | jumonji domain containing 1C | -0.0260164 |
| PRR11 | proline rich 11 | -0.0252896 |
| SYAP1 | synapse associated protein 1 | -0.025156 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0239939 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0238548 |
| DIAPH3 | diaphanous-related formin 3 | -0.0232677 |
| RASA2 | RAS p21 protein activator 2 | -0.0230057 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0229261 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0226018 |
| PLPP6 | phospholipid phosphatase 6 | -0.0225368 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0219895 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0215626 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0213171 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0212186 |
| GAS2L3 | growth arrest-specific 2 like 3 | -0.0209884 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0208506 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0208456 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0207507 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0206026 |
| PCBP2 | poly(rC) binding protein 2 | -0.0206 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.020599 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0203978 |
| PTMA | prothymosin, alpha | -0.020023 |
| TRAF3IP2 | TRAF3 interacting protein 2 | -0.0196548 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | -0.0196157 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0192956 |
| MATR3 | matrin 3 | -0.0192081 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | -0.0187873 |
| SET | SET nuclear proto-oncogene | -0.0187462 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0187097 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0187014 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0186221 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.018356 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0183475 |
| TXNRD1 | thioredoxin reductase 1 | -0.0181955 |
| ADM | adrenomedullin | -0.0177351 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0176685 |
| ATP13A3 | ATPase type 13A3 | -0.0174582 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0173835 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0173736 |
| NEK7 | NIMA-related kinase 7 | -0.0173583 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0173068 |
| KIF11 | kinesin family member 11 | -0.0172696 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0171937 |
| SRP54 | signal recognition particle 54kDa | -0.0170835 |
| USP47 | ubiquitin specific peptidase 47 | -0.0170048 |
| DENND4C | DENN/MADD domain containing 4C | -0.0169914 |
| SERINC1 | serine incorporator 1 | -0.0169673 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0169142 |
| RPS18 | ribosomal protein S18 | -0.0167362 |
| ARF4 | ADP-ribosylation factor 4 | -0.0166129 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | -0.0164597 |
| USP12 | ubiquitin specific peptidase 12 | -0.0163367 |
| NUP58 | nucleoporin 58 | -0.0162805 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0161765 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0161703 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0160896 |
