| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | activating transcription factor 1|This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6. [provided by RefSeq, Aug 2010] (NCBI Entrez Gene Database, 466) |
| External Link | https://ncbi.nlm.nih.gov/gene/466 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the ATF1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.00909503 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.00496327 |
| GPM6B | glycoprotein M6B | 0.00486198 |
| FOXG1 | forkhead box G1 | 0.00481701 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.00462984 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0044929 |
| AUTS2 | autism susceptibility candidate 2 | 0.00430189 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.00428148 |
| COG2 | component of oligomeric golgi complex 2 | 0.00423039 |
| DHDDS | dehydrodolichyl diphosphate synthase | 0.0042194 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00410186 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.00399207 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | 0.00396447 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00395731 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | 0.00392788 |
| DAPK1 | death-associated protein kinase 1 | 0.0038522 |
| RHOB | ras homolog family member B | 0.00380334 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | 0.00379885 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.00375093 |
| HMGB1 | high mobility group box 1 | 0.00374742 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00360921 |
| ACTA1 | actin, alpha 1, skeletal muscle | 0.0035831 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | 0.00355937 |
| NES | nestin | 0.00351853 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.00348729 |
| PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | 0.00347896 |
| COCH | cochlin | 0.00343849 |
| TTN | titin | 0.00340288 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.00339667 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | 0.00339365 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.00336796 |
| CCN2 | cellular communication network factor 2 | 0.00335778 |
| RRAD | Ras-related associated with diabetes | 0.00335272 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.00335107 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.00332484 |
| PDLIM1 | PDZ and LIM domain 1 | 0.00332212 |
| PENK | proenkephalin | 0.00329201 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.00325633 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 0.00325501 |
| DCLK1 | doublecortin-like kinase 1 | 0.00325024 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.00321941 |
| DCAF16 | DDB1 and CUL4 associated factor 16 | 0.00321938 |
| OGA | O-GlcNAcase | 0.00320469 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.00317961 |
| QKI | QKI, KH domain containing, RNA binding | 0.00316132 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | 0.00314557 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | 0.00314388 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) | 0.00313388 |
| DCLRE1C | DNA cross-link repair 1C | 0.00313285 |
| CPB1 | carboxypeptidase B1 (tissue) | 0.00312114 |
| LEFTY1 | left-right determination factor 1 | 0.00309068 |
| SVIL | supervillin | 0.00309057 |
| CIRBP | cold inducible RNA binding protein | 0.00306309 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.00305991 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.00304883 |
| USP13 | ubiquitin specific peptidase 13 (isopeptidase T-3) | 0.00304109 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00303249 |
| VWA5A | von Willebrand factor A domain containing 5A | 0.00302735 |
| RPL10 | ribosomal protein L10 | 0.00302436 |
| DNAJC16 | DnaJ (Hsp40) homolog, subfamily C, member 16 | 0.00301846 |
| TNNC1 | troponin C type 1 (slow) | 0.00299341 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.00298926 |
| NOTCH2NL | notch 2 N-terminal like | 0.00297942 |
| NOTCH3 | notch 3 | 0.00297297 |
| ITM2A | integral membrane protein 2A | 0.00296947 |
| WIF1 | WNT inhibitory factor 1 | 0.00296569 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | 0.00295482 |
| C8ORF4 | chromosome 8 open reading frame 4 | 0.00295068 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.00294862 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.00294841 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.00293444 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | 0.00290452 |
| KRT19 | keratin 19, type I | 0.00290209 |
| PGD | phosphogluconate dehydrogenase | 0.00290175 |
| MUC4 | mucin 4, cell surface associated | 0.00290163 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 0.00288562 |
| GLUL | glutamate-ammonia ligase | 0.00287375 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | 0.00287065 |
| PRDX2 | peroxiredoxin 2 | 0.0028677 |
| TULP4 | tubby like protein 4 | 0.00286686 |
| ACLY | ATP citrate lyase | 0.00286382 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00286037 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.00285116 |
| NCOA1 | nuclear receptor coactivator 1 | 0.002842 |
| MCOLN1 | mucolipin 1 | 0.00284145 |
| CLU | clusterin | 0.00283706 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.00283645 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00283485 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.00282759 |
| WDR61 | WD repeat domain 61 | 0.00282305 |
| COL4A5 | collagen, type IV, alpha 5 | 0.00281447 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.00280647 |
| COG5 | component of oligomeric golgi complex 5 | 0.00280419 |
| NPY1R | neuropeptide Y receptor Y1 | 0.0027874 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.00277941 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.00274279 |
| SLN | sarcolipin | 0.00273252 |
| CTTN | cortactin | 0.00272932 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.00272658 |
| ZBTB16 | zinc finger and BTB domain containing 16 | 0.00272491 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00272402 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.0027174 |
| ABLIM1 | actin binding LIM protein 1 | 0.00270991 |
| BIN1 | bridging integrator 1 | 0.00270697 |
| ATIC | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase | 0.00270257 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.00269766 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | 0.00269667 |
| GATAD2A | GATA zinc finger domain containing 2A | 0.00269652 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.00269451 |
| CREB1 | cAMP responsive element binding protein 1 | 0.00269035 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | 0.00268892 |
| GDI2 | GDP dissociation inhibitor 2 | 0.00267254 |
| GPX4 | glutathione peroxidase 4 | 0.00266996 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.0026465 |
| MPHOSPH6 | M-phase phosphoprotein 6 | 0.0026448 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.00264223 |
| HEATR1 | HEAT repeat containing 1 | 0.0026397 |
| SNX7 | sorting nexin 7 | 0.00263954 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 | 0.00263942 |
| ZC2HC1A | zinc finger, C2HC-type containing 1A | 0.0026314 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 | 0.00262813 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 | 0.00262412 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.00262406 |
| SIRT3 | sirtuin 3 | 0.00262337 |
| MYH11 | myosin, heavy chain 11, smooth muscle | 0.00261499 |
| CTSZ | cathepsin Z | 0.00260633 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00259155 |
| GPC3 | glypican 3 | 0.00256456 |
| CCL15 | chemokine (C-C motif) ligand 15 | 0.00256349 |
| EIF2B4 | eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa | 0.00255312 |
| BRD2 | bromodomain containing 2 | 0.00254997 |
| SMAD3 | SMAD family member 3 | 0.0025418 |
| TUBB4B | tubulin, beta 4B class IVb | 0.00253696 |
| CD1B | CD1b molecule | 0.00253425 |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.00253306 |
| SYBU | syntabulin (syntaxin-interacting) | 0.00253288 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.00252675 |
| PDGFC | platelet derived growth factor C | 0.00252334 |
| TUBB2B | tubulin, beta 2B class IIb | 0.0025199 |
| NAV3 | neuron navigator 3 | 0.00251524 |
| STK26 | serine/threonine protein kinase 26 | 0.00250898 |
| USP46 | ubiquitin specific peptidase 46 | 0.00250853 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.00250176 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00249838 |
| ZNF331 | zinc finger protein 331 | 0.0024955 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.00249505 |
| BBS4 | Bardet-Biedl syndrome 4 | 0.00249291 |
| RAI14 | retinoic acid induced 14 | 0.0024928 |
| EIF3F | eukaryotic translation initiation factor 3, subunit F | 0.00249254 |
| CASD1 | CAS1 domain containing 1 | 0.0024877 |
| KLHL41 | kelch-like family member 41 | 0.00248753 |
| FAM222B | family with sequence similarity 222, member B | 0.00248632 |
| EIF6 | eukaryotic translation initiation factor 6 | 0.00248035 |
| CYB5R1 | cytochrome b5 reductase 1 | 0.00247075 |
| ZNF22 | zinc finger protein 22 | 0.00246389 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | 0.00245411 |
| SPIN1 | spindlin 1 | 0.002452 |
| STK38 | serine/threonine kinase 38 | 0.00245161 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.00244703 |
| HPSE | heparanase | 0.00244542 |
| SCRG1 | stimulator of chondrogenesis 1 | 0.00244327 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | 0.00244193 |
| RORA | RAR-related orphan receptor A | 0.00244175 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.00243828 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.00243825 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 0.00243417 |
| PALMD | palmdelphin | 0.00243389 |
| FGF2 | fibroblast growth factor 2 (basic) | 0.00242502 |
| NAGK | N-acetylglucosamine kinase | 0.00241666 |
| MOCOS | molybdenum cofactor sulfurase | 0.00240992 |
| COL2A1 | collagen, type II, alpha 1 | 0.00240959 |
| ODC1 | ornithine decarboxylase 1 | 0.00240908 |
| VASH2 | vasohibin 2 | 0.00240287 |
| MYO5C | myosin VC | 0.00238286 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 | 0.00237609 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00237364 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.00237258 |
| ARL4A | ADP-ribosylation factor-like 4A | 0.0023691 |
| STAB1 | stabilin 1 | 0.00236881 |
| NSF | N-ethylmaleimide-sensitive factor | 0.00236503 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.0023649 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.00236406 |
| ZNF3 | zinc finger protein 3 | 0.00236101 |
| KYAT3 | kynurenine aminotransferase 3 | 0.0023561 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.00235605 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0023551 |
| NME5 | NME/NM23 family member 5 | 0.00235325 |
| MAGED1 | melanoma antigen family D1 | 0.00235044 |
| TNIK | TRAF2 and NCK interacting kinase | 0.00234468 |
| PCYOX1 | prenylcysteine oxidase 1 | 0.00233691 |
| MFAP3L | microfibrillar-associated protein 3-like | 0.00233565 |
| JAM3 | junctional adhesion molecule 3 | 0.00233032 |
| AASS | aminoadipate-semialdehyde synthase | 0.00232759 |
| TMEM63A | transmembrane protein 63A | 0.00232101 |
| MRS2 | MRS2 magnesium transporter | 0.00231938 |
| BPGM | 2,3-bisphosphoglycerate mutase | 0.00231927 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.00231696 |
| LEPROT | leptin receptor overlapping transcript | 0.00231531 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.0023098 |
| CCR7 | chemokine (C-C motif) receptor 7 | 0.00230593 |
| IRX5 | iroquois homeobox 5 | 0.00230478 |
| ANXA5 | annexin A5 | 0.00230358 |
| ALPK3 | alpha-kinase 3 | 0.00229627 |
| AKAP1 | A kinase (PRKA) anchor protein 1 | 0.00229061 |
| DNMBP | dynamin binding protein | 0.00228847 |
| NUCLEOLIN | nucleolin multifunctional protein | 0.00228417 |
| L1TD1 | LINE-1 type transposase domain containing 1 | 0.00228367 |
| TCP11L1 | t-complex 11, testis-specific-like 1 | 0.00228126 |
| IPO9 | importin 9 | 0.00227748 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.00227689 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.00227476 |
| NLGN1 | neuroligin 1 | 0.00227362 |
| BMP6 | bone morphogenetic protein 6 | 0.00226818 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.00226804 |
| CD1E | CD1e molecule | 0.00226159 |
| TNNC2 | troponin C type 2 (fast) | 0.00226111 |
| RXRA | retinoid X receptor, alpha | 0.00226046 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.00225581 |
| PER2 | period circadian clock 2 | 0.00225174 |
| WDR1 | WD repeat domain 1 | 0.00225109 |
| ATP5F1A | ATP synthase F1 subunit alpha | 0.00225092 |
| HAUS2 | HAUS augmin-like complex, subunit 2 | 0.00224867 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | 0.00224697 |
| VAMP3 | vesicle-associated membrane protein 3 | 0.0022414 |
| ICAM2 | intercellular adhesion molecule 2 | 0.00223682 |
| TLR2 | toll-like receptor 2 | 0.00223607 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | 0.00222362 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | 0.0022157 |
| OAZ1 | ornithine decarboxylase antizyme 1 | 0.00221183 |
| APOD | apolipoprotein D | 0.00220972 |
| SIK3 | SIK family kinase 3 | 0.00220614 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00220128 |
| TADA2A | transcriptional adaptor 2A | 0.00219918 |
| CD4 | CD4 molecule | 0.00219778 |
| DDOST | dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) | 0.00219752 |
| CES1 | carboxylesterase 1 | 0.00219638 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | 0.00219356 |
| RCHY1 | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase | 0.00219299 |
| WASF2 | WAS protein family, member 2 | 0.0021924 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.00218807 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.00218194 |
| CYB5R2 | cytochrome b5 reductase 2 | 0.0021817 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00218127 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.00217741 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.00217305 |
| KPNA6 | karyopherin alpha 6 (importin alpha 7) | 0.00216686 |
| USP11 | ubiquitin specific peptidase 11 | 0.00216162 |
| MGP | matrix Gla protein | 0.00216072 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.00216046 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCP4 | Purkinje cell protein 4 | -0.00681678 |
| PLXNC1 | plexin C1 | -0.0064176 |
| CLEC2B | C-type lectin domain family 2, member B | -0.0062862 |
| SRGN | serglycin | -0.00623471 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.00617235 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00592108 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00591804 |
| LUM | lumican | -0.005656 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00551345 |
| SPON2 | spondin 2, extracellular matrix protein | -0.00548223 |
| COL3A1 | collagen, type III, alpha 1 | -0.00538657 |
| RTN2 | reticulon 2 | -0.00522188 |
| LYPLA1 | lysophospholipase I | -0.005037 |
| PCNA | proliferating cell nuclear antigen | -0.00485409 |
| MMP1 | matrix metallopeptidase 1 | -0.00482453 |
| CAPG | capping protein (actin filament), gelsolin-like | -0.00473069 |
| FBXO21 | F-box protein 21 | -0.00468784 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | -0.00467037 |
| PWP1 | PWP1 homolog (S. cerevisiae) | -0.00462396 |
| INHBB | inhibin, beta B | -0.00460224 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00457301 |
| COL5A2 | collagen, type V, alpha 2 | -0.00445209 |
| HSPB1 | heat shock 27kDa protein 1 | -0.00438111 |
| TNS3 | tensin 3 | -0.00433943 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00432454 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.00429614 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | -0.00425542 |
| KRT8 | keratin 8, type II | -0.00424794 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.00423071 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00415006 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.00405467 |
| MXRA5 | matrix-remodelling associated 5 | -0.00404043 |
| LXN | latexin | -0.00404027 |
| TCTA | T-cell leukemia translocation altered | -0.00398607 |
| KIF20A | kinesin family member 20A | -0.00391503 |
| KLK10 | kallikrein-related peptidase 10 | -0.00389746 |
| PCLAF | PCNA clamp associated factor | -0.00388291 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00386927 |
| LYZ | lysozyme | -0.00384814 |
| DSP | desmoplakin | -0.00383498 |
| CTSH | cathepsin H | -0.00383192 |
| RACGAP1 | Rac GTPase activating protein 1 | -0.00382775 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00374728 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | -0.00370207 |
| CFB | complement factor B | -0.00367659 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00365549 |
| MT1F | metallothionein 1F | -0.00360512 |
| SLC25A46 | solute carrier family 25, member 46 | -0.00358747 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00358362 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00358095 |
| DTX4 | deltex 4, E3 ubiquitin ligase | -0.00357593 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.00355859 |
| LCN2 | lipocalin 2 | -0.00355663 |
| BST2 | bone marrow stromal cell antigen 2 | -0.0035554 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -0.00355489 |
| SST | somatostatin | -0.00355132 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | -0.00353298 |
| LOXL2 | lysyl oxidase-like 2 | -0.00352246 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00351203 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00349833 |
| TFF1 | trefoil factor 1 | -0.00349803 |
| HOPX | HOP homeobox | -0.00349221 |
| RNF167 | ring finger protein 167 | -0.00348374 |
| HHEX | hematopoietically expressed homeobox | -0.00347554 |
| KRT18 | keratin 18, type I | -0.00345798 |
| CCDC92 | coiled-coil domain containing 92 | -0.00344623 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 | -0.00344305 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.00344214 |
| ARF3 | ADP-ribosylation factor 3 | -0.00344146 |
| PRNP | prion protein | -0.00343647 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | -0.0034311 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00342228 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0033791 |
| WASF1 | WAS protein family, member 1 | -0.00337905 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.00335876 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.0033392 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00332241 |
| TMEM176B | transmembrane protein 176B | -0.00331783 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00330669 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00326327 |
| COL1A2 | collagen, type I, alpha 2 | -0.00325103 |
| PLS3 | plastin 3 | -0.00325005 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | -0.00322506 |
| PSMD9 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 | -0.00322352 |
| SORD | sorbitol dehydrogenase | -0.00322185 |
| SNAI2 | snail family zinc finger 2 | -0.00321863 |
| TMPO | thymopoietin | -0.00320971 |
| GNAS | GNAS complex locus | -0.0032045 |
| SNRPF | small nuclear ribonucleoprotein polypeptide F | -0.00318783 |
| MNDA | myeloid cell nuclear differentiation antigen | -0.00318149 |
| GAS1 | growth arrest-specific 1 | -0.00317997 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | -0.00313545 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.00313451 |
| C1ORF115 | chromosome 1 open reading frame 115 | -0.00312472 |
| PTTG1 | pituitary tumor-transforming 1 | -0.0031222 |
| GPSM3 | G-protein signaling modulator 3 | -0.00312186 |
| XYLT1 | xylosyltransferase I | -0.00308801 |
| IFI44 | interferon-induced protein 44 | -0.00308508 |
| PIGP | phosphatidylinositol glycan anchor biosynthesis, class P | -0.00308133 |
| CLTB | clathrin, light chain B | -0.00307028 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | -0.00306305 |
| PAM | peptidylglycine alpha-amidating monooxygenase | -0.00304738 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0030391 |
| SLC38A2 | solute carrier family 38, member 2 | -0.00303578 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.00303019 |
| MPPED2 | metallophosphoesterase domain containing 2 | -0.00302542 |
| GPX2 | glutathione peroxidase 2 | -0.00301934 |
| CCNB1 | cyclin B1 | -0.00301454 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00300079 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.00299801 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -0.00299609 |
| SEC24A | SEC24 family member A | -0.00299471 |
| HOXB2 | homeobox B2 | -0.00299306 |
| ZCCHC8 | zinc finger, CCHC domain containing 8 | -0.0029909 |
| FGF9 | fibroblast growth factor 9 | -0.00299033 |
| NDUFAB1 | NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa | -0.00298982 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.00298094 |
| RGS16 | regulator of G-protein signaling 16 | -0.00297552 |
| CSTA | cystatin A (stefin A) | -0.00296577 |
| FAM3C | family with sequence similarity 3, member C | -0.00295752 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.00292184 |
| MALL | mal, T-cell differentiation protein-like | -0.00291796 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00291649 |
| ISCU | iron-sulfur cluster assembly enzyme | -0.00291451 |
| OLFML2A | olfactomedin-like 2A | -0.00291377 |
| TDO2 | tryptophan 2,3-dioxygenase | -0.00290916 |
| EVI2A | ecotropic viral integration site 2A | -0.00290537 |
| CP | ceruloplasmin (ferroxidase) | -0.00289614 |
| LARP4 | La ribonucleoprotein domain family, member 4 | -0.00286288 |
| PSCA | prostate stem cell antigen | -0.00284436 |
| SOCS2 | suppressor of cytokine signaling 2 | -0.0028441 |
| S100P | S100 calcium binding protein P | -0.00283674 |
| PEBP1 | phosphatidylethanolamine binding protein 1 | -0.00283419 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.0028324 |
| TBC1D4 | TBC1 domain family, member 4 | -0.00283107 |
| CD200 | CD200 molecule | -0.00282447 |
| COL5A1 | collagen, type V, alpha 1 | -0.00282219 |
| EGFL6 | EGF-like-domain, multiple 6 | -0.00280876 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.00280552 |
| ASS1 | argininosuccinate synthase 1 | -0.00280452 |
| ADRA2A | adrenoceptor alpha 2A | -0.00280383 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.00280225 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.00280184 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.0027949 |
| PRC1 | protein regulator of cytokinesis 1 | -0.00278142 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00277482 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.00277443 |
| SNX10 | sorting nexin 10 | -0.0027722 |
| MT1H | metallothionein 1H | -0.00276677 |
| CDK2 | cyclin-dependent kinase 2 | -0.00275839 |
| KLK8 | kallikrein-related peptidase 8 | -0.00274932 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.00274398 |
| PITX1 | paired-like homeodomain 1 | -0.00273602 |
| MT1G | metallothionein 1G | -0.00272999 |
| CSRP2 | cysteine and glycine-rich protein 2 | -0.00272208 |
| CYTIP | cytohesin 1 interacting protein | -0.00271772 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0027131 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0027078 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00269795 |
| WASHC4 | WASH complex subunit 4 | -0.00269422 |
| MMP11 | matrix metallopeptidase 11 | -0.00269416 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.00269122 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00268492 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00268289 |
| IRF8 | interferon regulatory factor 8 | -0.00268266 |
| PLIN2 | perilipin 2 | -0.002668 |
| MX1 | MX dynamin-like GTPase 1 | -0.00266333 |
| ETV5 | ets variant 5 | -0.00265718 |
| MT1E | metallothionein 1E | -0.00264123 |
| DHFR | dihydrofolate reductase | -0.00263956 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00263582 |
| FASTKD5 | FAST kinase domains 5 | -0.00263494 |
| ATP5MJ | ATP synthase membrane subunit j | -0.00263161 |
| SCARB1 | scavenger receptor class B, member 1 | -0.00262436 |
| TTK | TTK protein kinase | -0.00261872 |
| ANXA4 | annexin A4 | -0.00261803 |
| TM4SF4 | transmembrane 4 L six family member 4 | -0.00261336 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | -0.00261282 |
| MT2A | metallothionein 2A | -0.00261221 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -0.00260598 |
| MMP9 | matrix metallopeptidase 9 | -0.00260027 |
| METTL7A | methyltransferase like 7A | -0.00259324 |
| STK17A | serine/threonine kinase 17a | -0.00259322 |
| HMGA2 | high mobility group AT-hook 2 | -0.00259124 |
| LIMA1 | LIM domain and actin binding 1 | -0.00258813 |
| TESC | tescalcin | -0.00258586 |
| MFAP5 | microfibrillar associated protein 5 | -0.00257524 |
| SEPHS2 | selenophosphate synthetase 2 | -0.00257033 |
| ZBTB11 | zinc finger and BTB domain containing 11 | -0.00256948 |
| NSG1 | neuron specific gene family member 1 | -0.00256607 |
| RHOH | ras homolog family member H | -0.00256282 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.00255667 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00255226 |
| THBS2 | thrombospondin 2 | -0.00254685 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00253796 |
| PLXDC1 | plexin domain containing 1 | -0.00253614 |
| TWF1 | twinfilin actin binding protein 1 | -0.00253179 |
| RGS1 | regulator of G-protein signaling 1 | -0.00252968 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0025265 |
| S100A8 | S100 calcium binding protein A8 | -0.00252626 |
| KIF14 | kinesin family member 14 | -0.00252563 |
| C1D | C1D nuclear receptor corepressor | -0.00251961 |
| UBE2N | ubiquitin-conjugating enzyme E2N | -0.00251926 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.00251828 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.00251627 |
| POP5 | processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) | -0.0025118 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | -0.00251016 |
| SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) | -0.00250941 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0024965 |
| WASHC3 | WASH complex subunit 3 | -0.00248579 |
| LOC105375355 | uroplakin-3b | -0.00248536 |
| TPD52 | tumor protein D52 | -0.00248387 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.00248335 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.00248183 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00247821 |
| TRAPPC6A | trafficking protein particle complex 6A | -0.00247251 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | -0.00247177 |
| VSNL1 | visinin-like 1 | -0.00247027 |
| ATP5PF | ATP synthase peripheral stalk subunit F6 | -0.00246613 |
| FKBP4 | FK506 binding protein 4, 59kDa | -0.00246569 |
| F12 | coagulation factor XII (Hageman factor) | -0.00246249 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.00246235 |
| NMU | neuromedin U | -0.00246142 |
| LRP4 | low density lipoprotein receptor-related protein 4 | -0.00246124 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | -0.00245714 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.00245476 |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase | -0.00245141 |
| KRT17 | keratin 17, type I | -0.00244796 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | -0.00244775 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | -0.00243879 |
| SLIRP | SRA stem-loop interacting RNA binding protein | -0.00243797 |
| RIN2 | Ras and Rab interactor 2 | -0.002437 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | -0.00243699 |
| EHF | ets homologous factor | -0.00242526 |
| ZWINT | ZW10 interacting kinetochore protein | -0.00242349 |
| TPST2 | tyrosylprotein sulfotransferase 2 | -0.00242107 |
| ZBED2 | zinc finger, BED-type containing 2 | -0.0024201 |
| NIT1 | nitrilase 1 | -0.00241809 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | -0.00241225 |
| TFRC | transferrin receptor | -0.00241176 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | -0.0024025 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.00240038 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00239978 |
| LRRC15 | leucine rich repeat containing 15 | -0.00239643 |
| ACTN4 | actinin, alpha 4 | -0.00239424 |
| ARPC3 | actin related protein 2/3 complex, subunit 3, 21kDa | -0.00239422 |
| NNMT | nicotinamide N-methyltransferase | -0.00239196 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0023885 |
| KLK11 | kallikrein-related peptidase 11 | -0.00238749 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | -0.00238632 |
