ATF2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description activating transcription factor 2|This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene [provided by RefSeq, Jan 2014] (NCBI Entrez Gene Database, 1386)
External Link https://ncbi.nlm.nih.gov/gene/1386
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Genes

500 genes differentially expressed following the ATF2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
S100A8 S100 calcium binding protein A8 0.019529
S100A9 S100 calcium binding protein A9 0.0159874
BMP4 bone morphogenetic protein 4 0.0136966
LTF lactotransferrin 0.0135456
TACSTD2 tumor-associated calcium signal transducer 2 0.0124895
CSTA cystatin A (stefin A) 0.0121122
RAD23B RAD23 homolog B (S. cerevisiae) 0.0120286
GLUL glutamate-ammonia ligase 0.011195
S100P S100 calcium binding protein P 0.0109979
PPL periplakin 0.0109069
HSPB1 heat shock 27kDa protein 1 0.010072
STXBP2 syntaxin binding protein 2 0.00954444
KRT13 keratin 13, type I 0.00946439
TGM2 transglutaminase 2 0.0094593
FABP4 fatty acid binding protein 4, adipocyte 0.0093789
SIAH2 siah E3 ubiquitin protein ligase 2 0.00927186
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00920166
TPD52L1 tumor protein D52-like 1 0.00911447
PSCA prostate stem cell antigen 0.00902065
NPEPL1 aminopeptidase-like 1 0.00892729
CXCL9 chemokine (C-X-C motif) ligand 9 0.00887334
YBX3 Y box binding protein 3 0.0088346
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 0.0086014
FXYD3 FXYD domain containing ion transport regulator 3 0.0085418
KRT15 keratin 15, type I 0.00853507
STOM stomatin 0.0084647
XPO7 exportin 7 0.00839835
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.00839544
TPM2 tropomyosin 2 (beta) 0.00832474
MYO5C myosin VC 0.00828814
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.0078839
RHCG Rh family, C glycoprotein 0.0077125
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.00770173
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00767914
KRT16 keratin 16, type I 0.00765674
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.00764995
KRT6A keratin 6A, type II 0.00763849
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.00755811
AHSP alpha hemoglobin stabilizing protein 0.00754896
SPRR1B small proline-rich protein 1B 0.00745646
PROCR protein C receptor, endothelial 0.00738053
KRT18 keratin 18, type I 0.00723849
MALL mal, T-cell differentiation protein-like 0.00715134
SYT1 synaptotagmin I 0.00712214
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00712089
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 0.00708607
GPD1L glycerol-3-phosphate dehydrogenase 1-like 0.00702644
DES desmin 0.00690477
MSMB microseminoprotein, beta- 0.00681808
CLU clusterin 0.00680674
LYZ lysozyme 0.00678473
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.00677542
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 0.00674091
CST3 cystatin C 0.0067099
SFRP1 secreted frizzled-related protein 1 0.00668208
PALLD palladin, cytoskeletal associated protein 0.00658185
SH3YL1 SH3 and SYLF domain containing 1 0.00657426
CLCA2 chloride channel accessory 2 0.00657421
S100A7 S100 calcium binding protein A7 0.00656659
C1S complement component 1, s subcomponent 0.00653629
C8ORF4 chromosome 8 open reading frame 4 0.00653049
TOX3 TOX high mobility group box family member 3 0.0064881
TBC1D4 TBC1 domain family, member 4 0.0064359
SELENOT selenoprotein T 0.00643575
CCNG2 cyclin G2 0.00642603
TNNT1 troponin T type 1 (skeletal, slow) 0.00642503
MLF2 myeloid leukemia factor 2 0.00642202
CRYAB crystallin, alpha B 0.00637258
S100A2 S100 calcium binding protein A2 0.0063714
BLNK B-cell linker 0.00632383
ELP1 elongator acetyltransferase complex subunit 1 0.00628343
ALAS2 5'-aminolevulinate synthase 2 0.00626511
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.00623294
NPY neuropeptide Y 0.0062202
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.00620379
FHL1 four and a half LIM domains 1 0.00618841
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.00617978
PLTP phospholipid transfer protein 0.00617345
DCK deoxycytidine kinase 0.00616912
S100A14 S100 calcium binding protein A14 0.00614144
SPRR3 small proline-rich protein 3 0.00613159
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00611692
HBD hemoglobin, delta 0.0060875
AMDHD2 amidohydrolase domain containing 2 0.0060872
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 0.00607256
CXCL13 chemokine (C-X-C motif) ligand 13 0.00606004
NNMT nicotinamide N-methyltransferase 0.00604706
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.005978
H1-0 H1.0 linker histone 0.00596807
KRT6B keratin 6B, type II 0.00596621
PRF1 perforin 1 (pore forming protein) 0.00595891
GRB14 growth factor receptor-bound protein 14 0.00595614
PCLAF PCNA clamp associated factor 0.00594549
SEC14L1 SEC14-like 1 (S. cerevisiae) 0.00594538
HSPB8 heat shock 22kDa protein 8 0.00593666
IGLL1 immunoglobulin lambda-like polypeptide 1 0.00588306
KRT7 keratin 7, type II 0.00588072
ZNF185 zinc finger protein 185 (LIM domain) 0.00588017
DMTN dematin actin binding protein 0.00583425
PTK2 protein tyrosine kinase 2 0.00582529
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.00577597
GYG1 glycogenin 1 0.005767
COBLL1 cordon-bleu WH2 repeat protein-like 1 0.00576398
SORBS1 sorbin and SH3 domain containing 1 0.00572725
SPRR1A small proline-rich protein 1A 0.00572128
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.00569023
PITX1 paired-like homeodomain 1 0.00566835
CFD complement factor D (adipsin) 0.00564753
PCP4 Purkinje cell protein 4 0.00560343
MNDA myeloid cell nuclear differentiation antigen 0.00559416
NMD3 NMD3 ribosome export adaptor 0.0055824
KAZN kazrin, periplakin interacting protein 0.00557995
NPY1R neuropeptide Y receptor Y1 0.0055782
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.0055409
GRB7 growth factor receptor-bound protein 7 0.00548187
CAPN1 calpain 1, (mu/I) large subunit 0.00547798
TCAP titin-cap 0.00545807
HIST1H2BD histone cluster 1, H2bd 0.00545529
SINHCAF SIN3-HDAC complex associated factor 0.00544693
PI3 peptidase inhibitor 3, skin-derived 0.00544124
ZBTB18 zinc finger and BTB domain containing 18 0.00543908
HIRA histone cell cycle regulator 0.00542245
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.00541824
TCF4 transcription factor 4 0.00540766
RBM38 RNA binding motif protein 38 0.0054076
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.00540718
ZBTB16 zinc finger and BTB domain containing 16 0.00539945
TSPAN13 tetraspanin 13 0.00539748
CA2 carbonic anhydrase II 0.00539679
ANXA1 annexin A1 0.00538235
C10ORF10 chromosome 10 open reading frame 10 0.00538063
MPO myeloperoxidase 0.00536246
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.00536083
LY6D lymphocyte antigen 6 complex, locus D 0.00534697
CXCL11 chemokine (C-X-C motif) ligand 11 0.00534646
SPTSSA serine palmitoyltransferase, small subunit A 0.00533948
APOD apolipoprotein D 0.00532927
GDE1 glycerophosphodiester phosphodiesterase 1 0.00531575
ANXA3 annexin A3 0.00531474
GSPT1 G1 to S phase transition 1 0.00529743
H1-2 H1.2 linker histone, cluster member 0.00528486
CYFIP1 cytoplasmic FMR1 interacting protein 1 0.0052763
NPTN neuroplastin 0.00526698
RC3H2 ring finger and CCCH-type domains 2 0.0052519
MUC1 mucin 1, cell surface associated 0.00525055
CD9 CD9 molecule 0.0052453
COMT catechol-O-methyltransferase 0.00524124
ADIRF adipogenesis regulatory factor 0.00521849
CCL19 chemokine (C-C motif) ligand 19 0.00520622
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.00520555
CRNN cornulin 0.00518965
MT1X metallothionein 1X 0.0051807
PLBD1 phospholipase B domain containing 1 0.00517629
PDAP1 PDGFA associated protein 1 0.00515001
MMP12 matrix metallopeptidase 12 0.00514012
MBOAT2 membrane bound O-acyltransferase domain containing 2 0.00512642
TMPRSS11E transmembrane protease, serine 11E 0.00511623
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 0.00511184
HSPA4L heat shock 70kDa protein 4-like 0.00510833
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 0.00510563
BSG basigin (Ok blood group) 0.00510442
SRRM2 serine/arginine repetitive matrix 2 0.00509994
EGR1 early growth response 1 0.00509462
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 0.00509403
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.00505837
TLE5 TLE family member 5, transcriptional modulator 0.00504959
UGCG UDP-glucose ceramide glucosyltransferase 0.00503259
SMAD6 SMAD family member 6 0.00503155
FGF13 fibroblast growth factor 13 0.00501653
RHOB ras homolog family member B 0.00499594
RNF6 ring finger protein (C3H2C3 type) 6 0.00499483
UBE2H ubiquitin-conjugating enzyme E2H 0.00498968
TOM1L1 target of myb1 (chicken)-like 1 0.004984
NUPR1 nuclear protein, transcriptional regulator, 1 0.0049831
E2F2 E2F transcription factor 2 0.00498097
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.004979
FAM3C family with sequence similarity 3, member C 0.00497803
ACSL1 acyl-CoA synthetase long-chain family member 1 0.00497039
SLURP1 secreted LY6/PLAUR domain containing 1 0.00496111
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 0.00495558
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 0.00495455
CAVIN2 caveolae associated protein 2 0.00495429
BPGM 2,3-bisphosphoglycerate mutase 0.00492056
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.00491139
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 0.00489861
CTSW cathepsin W 0.00489506
BAZ1A bromodomain adjacent to zinc finger domain, 1A 0.0048823
TRIM29 tripartite motif containing 29 0.00488207
COPS7A COP9 signalosome subunit 7A 0.00487929
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 0.00487651
RHOA ras homolog family member A 0.00486008
MT1G metallothionein 1G 0.00485577
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.00483687
SPRR2B small proline-rich protein 2B 0.00482501
GCLC glutamate-cysteine ligase, catalytic subunit 0.00480764
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 0.00480463
PNPLA2 patatin-like phospholipase domain containing 2 0.00478222
MGP matrix Gla protein 0.00477013
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.00476631
C2CD2 C2 calcium-dependent domain containing 2 0.00475895
KRT5 keratin 5, type II 0.00475588
GTF2A2 general transcription factor IIA, 2, 12kDa 0.004752
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 0.00472501
CLCN3 chloride channel, voltage-sensitive 3 0.00471826
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.00468883
PCNA proliferating cell nuclear antigen 0.00467967
MPP1 membrane protein, palmitoylated 1, 55kDa 0.00467475
PERP PERP, TP53 apoptosis effector 0.00467239
CRYM crystallin, mu 0.00466693
CHRDL1 chordin-like 1 0.00466581
DLG1 discs, large homolog 1 (Drosophila) 0.00466143
MTMR1 myotubularin related protein 1 0.00465791
CENPU centromere protein U 0.00464511
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) 0.00463685
PRKCZ protein kinase C, zeta 0.00462936
KLF1 Kruppel-like factor 1 (erythroid) 0.00462733
TGM1 transglutaminase 1 0.00462052
PALMD palmdelphin 0.00460963
CLIP1 CAP-GLY domain containing linker protein 1 0.0046069
CSRP2 cysteine and glycine-rich protein 2 0.00460276
LYPD3 LY6/PLAUR domain containing 3 0.00458967
PDE8B phosphodiesterase 8B 0.00457324
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) 0.00455651
PRSS8 protease, serine, 8 0.00455578
PTMS parathymosin 0.00454966
SLC30A1 solute carrier family 30 (zinc transporter), member 1 0.00454249
RCAN1 regulator of calcineurin 1 0.00452887
CST1 cystatin SN 0.00452642
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.00452409
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.00452177
LUC7L2 LUC7-like 2 (S. cerevisiae) 0.00451899
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.00451726
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 0.00451493
TPM4 tropomyosin 4 0.00450849
TTN titin 0.00450218
KDM7A lysine (K)-specific demethylase 7A 0.00449845
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 0.00449181
MAN1A1 mannosidase, alpha, class 1A, member 1 0.00448932
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.00448548
KAT2B K(lysine) acetyltransferase 2B 0.00447905
MYBPC1 myosin binding protein C, slow type 0.00447543
TJP2 tight junction protein 2 0.00447452
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa 0.00446723
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.00446014
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 0.00445934
HHEX hematopoietically expressed homeobox 0.00445162
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.00445078
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein 0.00444784
SRSF1 serine/arginine-rich splicing factor 1 0.00443051
P3H2 prolyl 3-hydroxylase 2 0.00442451

decreased expression

Symbol Name Standardized Value
THBS1 thrombospondin 1 -0.0137837
DLK1 delta-like 1 homolog (Drosophila) -0.0121694
VNN1 vanin 1 -0.0114916
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.0110187
FCGBP Fc fragment of IgG binding protein -0.0105829
CRABP1 cellular retinoic acid binding protein 1 -0.0102392
MFAP2 microfibrillar-associated protein 2 -0.0101066
TUBB2B tubulin, beta 2B class IIb -0.010065
MARCKS myristoylated alanine-rich protein kinase C substrate -0.00992137
IFI6 interferon, alpha-inducible protein 6 -0.00974131
ASS1 argininosuccinate synthase 1 -0.00941233
EGR2 early growth response 2 -0.00931696
CLCA1 chloride channel accessory 1 -0.00902934
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.00892062
GSTM3 glutathione S-transferase mu 3 (brain) -0.00870407
THBS2 thrombospondin 2 -0.00869998
NPTX2 neuronal pentraxin II -0.00841601
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -0.00838081
TXLNA taxilin alpha -0.00825925
HAL histidine ammonia-lyase -0.0082275
PEG3 paternally expressed 3 -0.00814833
SCG5 secretogranin V -0.00780666
HOXD1 homeobox D1 -0.00778638
IER5 immediate early response 5 -0.00772425
SNAI2 snail family zinc finger 2 -0.00762832
TOX thymocyte selection-associated high mobility group box -0.00754697
TYRP1 tyrosinase-related protein 1 -0.0074006
CGA glycoprotein hormones, alpha polypeptide -0.00726053
CADM1 cell adhesion molecule 1 -0.00708824
FABP7 fatty acid binding protein 7, brain -0.00702057
PTHLH parathyroid hormone-like hormone -0.00693505
TADA2A transcriptional adaptor 2A -0.00689429
ISG15 ISG15 ubiquitin-like modifier -0.00688538
ADD3 adducin 3 (gamma) -0.00688197
STK10 serine/threonine kinase 10 -0.00686001
MOXD1 monooxygenase, DBH-like 1 -0.00684036
COL9A2 collagen, type IX, alpha 2 -0.00682268
NVL nuclear VCP-like -0.0068019
PELI1 pellino E3 ubiquitin protein ligase 1 -0.00678554
CD83 CD83 molecule -0.00675153
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 -0.00670694
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 -0.00667476
RGS1 regulator of G-protein signaling 1 -0.00667055
POSTN periostin, osteoblast specific factor -0.0066333
SALL2 spalt-like transcription factor 2 -0.00659667
GUSBP3 glucuronidase, beta pseudogene 3 -0.006548
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -0.00649927
WT1 Wilms tumor 1 -0.0064117
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.00641083
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 -0.00639086
XIC X chromosome inactivation center -0.00637456
PEG10 paternally expressed 10 -0.00630767
ZNF721 zinc finger protein 721 -0.00628723
PTGER4 prostaglandin E receptor 4 (subtype EP4) -0.00627905
PADI2 peptidyl arginine deiminase, type II -0.00623395
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.00621875
GMFG glia maturation factor, gamma -0.00609838
KIF3B kinesin family member 3B -0.00606759
MX1 MX dynamin-like GTPase 1 -0.00606322
DOK5 docking protein 5 -0.0060581
MX2 MX dynamin-like GTPase 2 -0.00604734
SOX10 SRY (sex determining region Y)-box 10 -0.00604493
ARHGAP15 Rho GTPase activating protein 15 -0.00598912
FTH1 ferritin, heavy polypeptide 1 -0.00598133
LGALS4 lectin, galactoside-binding, soluble, 4 -0.00592332
PCOLCE procollagen C-endopeptidase enhancer -0.00587682
IGFBP1 insulin-like growth factor binding protein 1 -0.00585672
CCL20 chemokine (C-C motif) ligand 20 -0.00583383
NPIPB3 nuclear pore complex interacting protein family, member B3 -0.00581461
NSG1 neuron specific gene family member 1 -0.00580687
GAS2 growth arrest-specific 2 -0.00578222
COL11A1 collagen, type XI, alpha 1 -0.00578029
LYPD1 LY6/PLAUR domain containing 1 -0.00577711
ARMCX2 armadillo repeat containing, X-linked 2 -0.00575934
OLFML3 olfactomedin-like 3 -0.0057584
ZNF160 zinc finger protein 160 -0.00574294
LAPTM4B lysosomal protein transmembrane 4 beta -0.00574113
NID2 nidogen 2 (osteonidogen) -0.00570237
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.00569834
MUC2 mucin 2, oligomeric mucus/gel-forming -0.00567017
ICAM2 intercellular adhesion molecule 2 -0.0056584
COL6A3 collagen, type VI, alpha 3 -0.00563913
EFNB2 ephrin-B2 -0.00562088
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 -0.00562062
NOTCH2NL notch 2 N-terminal like -0.00561956
PIEZO2 piezo-type mechanosensitive ion channel component 2 -0.00559188
PLLP plasmolipin -0.00556524
TKTL1 transketolase-like 1 -0.00552437
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 -0.00551945
FST follistatin -0.00551374
OLFML2A olfactomedin-like 2A -0.00551121
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 -0.00549985
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.00547218
ADGRG2 adhesion G protein-coupled receptor G2 -0.00546952
HNMT histamine N-methyltransferase -0.005451
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene) -0.00544669
FBXO2 F-box protein 2 -0.00543957
EPHB2 EPH receptor B2 -0.00543946
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -0.00543542
PON3 paraoxonase 3 -0.00542768
GPR183 G protein-coupled receptor 183 -0.00542199
CEMIP cell migration inducing protein, hyaluronan binding -0.00541882
COL3A1 collagen, type III, alpha 1 -0.00541726
LYPLA1 lysophospholipase I -0.00540409
PPIF peptidylprolyl isomerase F -0.00540183
ZBTB10 zinc finger and BTB domain containing 10 -0.00539974
COL1A2 collagen, type I, alpha 2 -0.00539048
DCHS1 dachsous cadherin-related 1 -0.00537634
GPA33 glycoprotein A33 (transmembrane) -0.00537113
KIF1A kinesin family member 1A -0.00536186
NANOG Nanog homeobox -0.00534576
IL1RAP interleukin 1 receptor accessory protein -0.00534427
SHTN1 shootin 1 -0.00533253
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase -0.00533218
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.0053258
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.00531518
BEX4 brain expressed, X-linked 4 -0.00527722
BHLHE41 basic helix-loop-helix family, member e41 -0.00527367
CYB561 cytochrome b561 -0.00526121
LAGE3 L antigen family, member 3 -0.00525512
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 -0.00525478
FNBP1 formin binding protein 1 -0.00525204
NES nestin -0.00525136
L1CAM L1 cell adhesion molecule -0.00525026
GAL galanin/GMAP prepropeptide -0.00524914
ADAT1 adenosine deaminase, tRNA-specific 1 -0.00523529
INHBB inhibin, beta B -0.00519975
PDLIM1 PDZ and LIM domain 1 -0.00519491
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) -0.00519184
SPRED2 sprouty-related, EVH1 domain containing 2 -0.00517691
FXYD6 FXYD domain containing ion transport regulator 6 -0.00517639
TWIST1 twist family bHLH transcription factor 1 -0.00517568
PRKCA protein kinase C, alpha -0.00513668
COL9A3 collagen, type IX, alpha 3 -0.00510188
ALB albumin -0.00508793
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00508376
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00506604
KCNK12 potassium channel, two pore domain subfamily K, member 12 -0.00506495
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00506494
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.00505411
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.00503395
ATP10B ATPase, class V, type 10B -0.0050139
PECR peroxisomal trans-2-enoyl-CoA reductase -0.005004
TRIM36 tripartite motif containing 36 -0.00499564
PTBP2 polypyrimidine tract binding protein 2 -0.00498059
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.00497266
PNMA8A PNMA family member 8A -0.00497135
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 -0.00496478
MPZ myelin protein zero -0.00496211
ADGRG6 adhesion G protein-coupled receptor G6 -0.00496017
CRYBG3 beta-gamma crystallin domain containing 3 -0.00495975
FABP1 fatty acid binding protein 1, liver -0.00495466
L1TD1 LINE-1 type transposase domain containing 1 -0.00495278
DCT dopachrome tautomerase -0.00495014
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) -0.00494858
NLRP2 NLR family, pyrin domain containing 2 -0.00494552
PITX3 paired-like homeodomain 3 -0.0049454
SH3BP5 SH3-domain binding protein 5 (BTK-associated) -0.004935
ATF3 activating transcription factor 3 -0.00493307
QKI QKI, KH domain containing, RNA binding -0.00492984
NAV2 neuron navigator 2 -0.00492628
ETFB electron-transfer-flavoprotein, beta polypeptide -0.00492575
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -0.00492351
IL6R interleukin 6 receptor -0.00491158
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00489779
SNX7 sorting nexin 7 -0.00489452
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -0.00488993
CBS cystathionine-beta-synthase -0.00487518
HIP1 huntingtin interacting protein 1 -0.00485959
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) -0.00483734
DPYSL3 dihydropyrimidinase-like 3 -0.00483216
POPDC3 popeye domain containing 3 -0.00481484
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 -0.00481444
LEFTY1 left-right determination factor 1 -0.00481191
ZNF611 zinc finger protein 611 -0.00480768
NCOA2 nuclear receptor coactivator 2 -0.00479903
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -0.00479884
ZIC1 Zic family member 1 -0.00479709
CDH17 cadherin 17, LI cadherin (liver-intestine) -0.00479291
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -0.00479195
C3AR1 complement component 3a receptor 1 -0.00478931
SELPLG selectin P ligand -0.00477068
IL13RA2 interleukin 13 receptor, alpha 2 -0.00474848
GNAS GNAS complex locus -0.00473974
C14ORF132 chromosome 14 open reading frame 132 -0.00473626
MMP19 matrix metallopeptidase 19 -0.00473548
BTNL8 butyrophilin-like 8 -0.00471684
CREM cAMP responsive element modulator -0.00469035
SHB Src homology 2 domain containing adaptor protein B -0.00468763
EPS8L3 EPS8-like 3 -0.00468567
CRIP1 cysteine-rich protein 1 (intestinal) -0.00468561
CRELD2 cysteine-rich with EGF-like domains 2 -0.00465981
SMAD2 SMAD family member 2 -0.00464505
MRPL19 mitochondrial ribosomal protein L19 -0.00464184
ITPKB inositol-trisphosphate 3-kinase B -0.00464179
NAP1L2 nucleosome assembly protein 1-like 2 -0.00463968
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.00463107
NR1I2 nuclear receptor subfamily 1, group I, member 2 -0.00461583
HSPA2 heat shock 70kDa protein 2 -0.00461342
OPTN optineurin -0.00460721
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -0.00459989
SPINK4 serine peptidase inhibitor, Kazal type 4 -0.00459347
WNT5B wingless-type MMTV integration site family, member 5B -0.00457989
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa -0.00456089
PHACTR1 phosphatase and actin regulator 1 -0.00454543
TCEAL2 transcription elongation factor A (SII)-like 2 -0.00454229
DSC1 desmocollin 1 -0.00453754
TMEM255A transmembrane protein 255A -0.00453349
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.00453268
QPRT quinolinate phosphoribosyltransferase -0.00453013
TMBIM4 transmembrane BAX inhibitor motif containing 4 -0.00453001
AFP alpha-fetoprotein -0.00452901
CPVL carboxypeptidase, vitellogenic-like -0.00452569
EPB41L3 erythrocyte membrane protein band 4.1-like 3 -0.00452089
IFITM1 interferon induced transmembrane protein 1 -0.00451528
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal -0.00450868
TP53I3 tumor protein p53 inducible protein 3 -0.00450706
PLXNC1 plexin C1 -0.00448777
NDFIP1 Nedd4 family interacting protein 1 -0.00448045
MXRA5 matrix-remodelling associated 5 -0.00447835
MAGED2 melanoma antigen family D2 -0.00447636
BNC2 basonuclin 2 -0.00446997
CAVIN3 caveolae associated protein 3 -0.00445712
SPON1 spondin 1, extracellular matrix protein -0.00444519
AURKB aurora kinase B -0.00443372
GOLGA8H golgin A8 family, member H -0.00442947
GPR137B G protein-coupled receptor 137B -0.00442658
NBPF10 neuroblastoma breakpoint family, member 10 -0.00442638
RUNX3 runt-related transcription factor 3 -0.00442312
WIPF1 WAS/WASL interacting protein family, member 1 -0.00441857
FBXO11 F-box protein 11 -0.00441656
SYT11 synaptotagmin XI -0.00441647
BPHL biphenyl hydrolase-like (serine hydrolase) -0.00441374
PLK1 polo-like kinase 1 -0.0044102
ANXA6 annexin A6 -0.0044069
PRR11 proline rich 11 -0.00440409
BICC1 BicC family RNA binding protein 1 -0.00440147
CLEC2B C-type lectin domain family 2, member B -0.00439984
PPT1 palmitoyl-protein thioesterase 1 -0.00439414
TBC1D12 TBC1 domain family, member 12 -0.0043899
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta -0.00438486
RPS14P3 ribosomal protein S14 pseudogene 3 -0.00438015
SLCO3A1 solute carrier organic anion transporter family, member 3A1 -0.0043758
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.00436219
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 -0.00436084
ILVBL ilvB (bacterial acetolactate synthase)-like -0.00434681
SOWAHC sosondowah ankyrin repeat domain family member C -0.00433121
HAUS2 HAUS augmin-like complex, subunit 2 -0.00432872
RNF144A ring finger protein 144A -0.00432721
FKBP9 FK506 binding protein 9, 63 kDa -0.00431871