ATF2 Gene Set

Dataset MotifMap Predicted Transcription Factor Targets
Category genomics
Type transcription factor
Description activating transcription factor 2|This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene [provided by RefSeq, Jan 2014] (NCBI Entrez Gene Database, 1386)
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Genes

31 target genes of the ATF2 transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

Symbol Name
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa
C3ORF14 chromosome 3 open reading frame 14
CD2AP CD2-associated protein
CDC5L cell division cycle 5-like
CLCN3 chloride channel, voltage-sensitive 3
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
DBN1 drebrin 1
DNTTIP1 deoxynucleotidyltransferase, terminal, interacting protein 1
GPR3 G protein-coupled receptor 3
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
LRRC8A leucine rich repeat containing 8 family, member A
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha
MIR124-2 microRNA 124-2
MIR124-3 microRNA 124-3
MIR4530 microRNA 4530
MYCBPAP MYCBP associated protein
NEDD1 neural precursor cell expressed, developmentally down-regulated 1
NF1 neurofibromin 1
NOTCH4 notch 4
OXSR1 oxidative stress responsive 1
PFAS phosphoribosylformylglycinamidine synthase
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
RFC3 replication factor C (activator 1) 3, 38kDa
RNF7 ring finger protein 7
SLC25A25 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
SPAG4 sperm associated antigen 4
STXBP3 syntaxin binding protein 3
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TMEM187 transmembrane protein 187
TSPAN7 tetraspanin 7
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta