| Dataset | MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | gene perturbation identified as [gene symbol]_[perturbation or condition] (Molecular Signatures Database) |
| External Link | http://www.broadinstitute.org/gsea/msigdb/cards/ATF2_UP.V1_UP |
| Similar Terms | |
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375 genes differentially expressed following the ATF2_UP.V1 gene perturbation from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.
| Symbol | Name |
|---|---|
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ABLIM3 | actin binding LIM protein family, member 3 |
| ADAM28 | ADAM metallopeptidase domain 28 |
| ADM2 | adrenomedullin 2 |
| AKAP4 | A kinase (PRKA) anchor protein 4 |
| ALLC | allantoicase |
| ALOX12 | arachidonate 12-lipoxygenase |
| ALX3 | ALX homeobox 3 |
| AMELY | amelogenin, Y-linked |
| ANKRD11 | ankyrin repeat domain 11 |
| ANKRD34C | ankyrin repeat domain 34C |
| APAF1 | apoptotic peptidase activating factor 1 |
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 |
| APOD | apolipoprotein D |
| ARHGAP22 | Rho GTPase activating protein 22 |
| ARSJ | arylsulfatase family, member J |
| ASPN | asporin |
| ATP13A2 | ATPase type 13A2 |
| BAALC | brain and acute leukemia, cytoplasmic |
| BAIAP3 | BAI1-associated protein 3 |
| BRAP | BRCA1 associated protein |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C2CD2L | C2CD2-like |
| C3AR1 | complement component 3a receptor 1 |
| C8ORF4 | chromosome 8 open reading frame 4 |
| CA14 | carbonic anhydrase XIV |
| CARD9 | caspase recruitment domain family, member 9 |
| CBX5 | chromobox homolog 5 |
| CCDC94 | coiled-coil domain containing 94 |
| CCR4 | chemokine (C-C motif) receptor 4 |
| CD19 | CD19 molecule |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CD8A | CD8a molecule |
| CENPO | centromere protein O |
| CENPU | centromere protein U |
| CEP41 | centrosomal protein 41kDa |
| CHRNG | cholinergic receptor, nicotinic, gamma (muscle) |
| CLDN1 | claudin 1 |
| CLDN15 | claudin 15 |
| CNTN5 | contactin 5 |
| COL2A1 | collagen, type II, alpha 1 |
| CORO2B | coronin, actin binding protein, 2B |
| CST5 | cystatin D |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DENND2A | DENN/MADD domain containing 2A |
| DGKZ | diacylglycerol kinase, zeta |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 |
| DNASE2B | deoxyribonuclease II beta |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| EFHD1 | EF-hand domain family, member D1 |
| EMILIN2 | elastin microfibril interfacer 2 |
| ENDOG | endonuclease G |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FAM102A | family with sequence similarity 102, member A |
| FANCF | Fanconi anemia, complementation group F |
| FGF16 | fibroblast growth factor 16 |
| FGF20 | fibroblast growth factor 20 |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| FGR | FGR proto-oncogene, Src family tyrosine kinase |
| FOXG1 | forkhead box G1 |
| FOXL2 | forkhead box L2 |
| FOXM1 | forkhead box M1 |
| FRMD1 | FERM domain containing 1 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| FSHB | follicle stimulating hormone, beta polypeptide |
| G0S2 | G0/G1 switch 2 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 |
| GALR2 | galanin receptor 2 |
| GDF10 | growth differentiation factor 10 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GINS3 | GINS complex subunit 3 (Psf3 homolog) |
| GMPPB | GDP-mannose pyrophosphorylase B |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GPR63 | G protein-coupled receptor 63 |
| GPX5 | glutathione peroxidase 5 |
| GRAP | GRB2-related adaptor protein |
| GSTT2 | glutathione S-transferase theta 2 (gene/pseudogene) |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| GUCA1A | guanylate cyclase activator 1A (retina) |
| GZMK | granzyme K (granzyme 3; tryptase II) |
| HMX1 | H6 family homeobox 1 |
| HOXB1 | homeobox B1 |
| HOXD1 | homeobox D1 |
| HOXD11 | homeobox D11 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HSD3B1 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| ICAM2 | intercellular adhesion molecule 2 |
| IGF2 | insulin-like growth factor 2 |
| IL32 | interleukin 32 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat |
| ITGA8 | integrin, alpha 8 |
| KCNA2 | potassium channel, voltage gated shaker related subfamily A, member 2 |
| KCNAB3 | potassium channel, voltage gated subfamily A regulatory beta subunit 3 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| KISS1 | KiSS-1 metastasis-suppressor |
| KRT7 | keratin 7, type II |
| KRT81 | keratin 81, type II |
| LAS1L | LAS1-like (S. cerevisiae) |
| LIG1 | ligase I, DNA, ATP-dependent |
| LILRA5 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 |
| LIPE | lipase, hormone-sensitive |
| LRTM1 | leucine-rich repeats and transmembrane domains 1 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MAGEC3 | melanoma antigen family C3 |
| MAP2 | microtubule-associated protein 2 |
| MAS1 | MAS1 proto-oncogene, G protein-coupled receptor |
| MELK | maternal embryonic leucine zipper kinase |
| MMP1 | matrix metallopeptidase 1 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 |
| NCAPG | non-SMC condensin I complex, subunit G |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NEFL | neurofilament, light polypeptide |
| NEFM | neurofilament, medium polypeptide |
| NEO1 | neogenin 1 |
| NES | nestin |
| NEUROG1 | neurogenin 1 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 |
| NNAT | neuronatin |
| NRXN2 | neurexin 2 |
| OR10C1 | olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene) |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) |
| PAX1 | paired box 1 |
| PCDH1 | protocadherin 1 |
| PCDHA9 | protocadherin alpha 9 |
| PCP4 | Purkinje cell protein 4 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor |
| PELP1 | proline, glutamate and leucine rich protein 1 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PITX1 | paired-like homeodomain 1 |
| PLAU | plasminogen activator, urokinase |
| PLBD1 | phospholipase B domain containing 1 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLCB4 | phospholipase C, beta 4 |
| PLK4 | polo-like kinase 4 |
| PLXNB3 | plexin B3 |
| PNLIP | pancreatic lipase |
| PODXL | podocalyxin-like |
| POLD1 | polymerase (DNA directed), delta 1, catalytic subunit |
| PRKCD | protein kinase C, delta |
| PRMT8 | protein arginine methyltransferase 8 |
| PRSS50 | protease, serine, 50 |
| PTDSS2 | phosphatidylserine synthase 2 |
| PTGER1 | prostaglandin E receptor 1 (subtype EP1), 42kDa |
| PTPRT | protein tyrosine phosphatase, receptor type, T |
| RAD51 | RAD51 recombinase |
| RBP1 | retinol binding protein 1, cellular |
| REEP2 | receptor accessory protein 2 |
| RNF2 | ring finger protein 2 |
| RNF43 | ring finger protein 43 |
| RSPH6A | radial spoke head 6 homolog A (Chlamydomonas) |
| S100A4 | S100 calcium binding protein A4 |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SPRR2C | small proline-rich protein 2C (pseudogene) |
| STAT5A | signal transducer and activator of transcription 5A |
| STEAP1B | STEAP family member 1B |
| STRA6 | stimulated by retinoic acid 6 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TBC1D29 | TBC1 domain family, member 29 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 |
| TK1 | thymidine kinase 1, soluble |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
| TRIM14 | tripartite motif containing 14 |
| TRIM9 | tripartite motif containing 9 |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| TSC22D4 | TSC22 domain family, member 4 |
| TSPAN32 | tetraspanin 32 |
| TSSK2 | testis-specific serine kinase 2 |
| UPP1 | uridine phosphorylase 1 |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| VRTN | vertebrae development associated |
| WNT5B | wingless-type MMTV integration site family, member 5B |
| ZFR2 | zinc finger RNA binding protein 2 |
| ZNF324B | zinc finger protein 324B |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| AADAC | arylacetamide deacetylase |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ACACA | acetyl-CoA carboxylase alpha |
| ACVR2A | activin A receptor, type IIA |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADORA2B | adenosine A2b receptor |
| AFF1 | AF4/FMR2 family, member 1 |
| AIRE | autoimmune regulator |
| AK4 | adenylate kinase 4 |
| AK4P3 | adenylate kinase 4 pseudogene 3 |
| ANXA10 | annexin A10 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 |
| ATP8B4 | ATPase, class I, type 8B, member 4 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BHMT | betaine--homocysteine S-methyltransferase |
| C10ORF10 | chromosome 10 open reading frame 10 |
| C1RL | complement component 1, r subcomponent-like |
| CA9 | carbonic anhydrase IX |
| CCK | cholecystokinin |
| CCL11 | chemokine (C-C motif) ligand 11 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD1B | CD1b molecule |
| CD200 | CD200 molecule |
| CD302 | CD302 molecule |
| CD68 | CD68 molecule |
| CDH13 | cadherin 13 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CECR1 | cat eye syndrome chromosome region, candidate 1 |
| CELF2 | CUGBP, Elav-like family member 2 |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CFB | complement factor B |
| CFH | complement factor H |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| COMP | cartilage oligomeric matrix protein |
| CRLF1 | cytokine receptor-like factor 1 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CTH | cystathionine gamma-lyase |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| CYBRD1 | cytochrome b reductase 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DENND2D | DENN/MADD domain containing 2D |
| DENND4C | DENN/MADD domain containing 4C |
| DGKD | diacylglycerol kinase, delta 130kDa |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| EDNRA | endothelin receptor type A |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 |
| ERO1L | ERO1-like (S. cerevisiae) |
| EVC | Ellis van Creveld protein |
| FAM198B | family with sequence similarity 198, member B |
| FBLN2 | fibulin 2 |
| FGF7 | fibroblast growth factor 7 |
| FGF9 | fibroblast growth factor 9 |
| FMOD | fibromodulin |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FRY | furry homolog (Drosophila) |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GAS1 | growth arrest-specific 1 |
| GCH1 | GTP cyclohydrolase 1 |
| GLRA2 | glycine receptor, alpha 2 |
| GOLGA8A | golgin A8 family, member A |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C |
| GSR | glutathione reductase |
| GSTT1 | glutathione S-transferase theta 1 |
| GUCA1B | guanylate cyclase activator 1B (retina) |
| HAPLN1 | hyaluronan and proteoglycan link protein 1 |
| HDHD3 | haloacid dehalogenase-like hydrolase domain containing 3 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 |
| HKDC1 | hexokinase domain containing 1 |
| HMG20A | high mobility group 20A |
| HOXB2 | homeobox B2 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IL1R1 | interleukin 1 receptor, type I |
| IL1RAP | interleukin 1 receptor accessory protein |
| IL33 | interleukin 33 |
| IQCG | IQ motif containing G |
| IRS2 | insulin receptor substrate 2 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 |
| JUP | junction plakoglobin |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KCTD12 | potassium channel tetramerization domain containing 12 |
| KEL | Kell blood group, metallo-endopeptidase |
| KLHL21 | kelch-like family member 21 |
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 |
| LIMCH1 | LIM and calponin homology domains 1 |
| LOC399491 | |
| MFAP4 | microfibrillar-associated protein 4 |
| MN1 | meningioma (disrupted in balanced translocation) 1 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MYH3 | myosin, heavy chain 3, skeletal muscle, embryonic |
| MYO1D | myosin ID |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFIB | nuclear factor I/B |
| NPPB | natriuretic peptide B |
| NUPL1 | nucleoporin like 1 |
| PC | pyruvate carboxylase |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDLIM3 | PDZ and LIM domain 3 |
| PDPN | podoplanin |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 |
| PER3 | period circadian clock 3 |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PIP | prolactin-induced protein |
| PISD | phosphatidylserine decarboxylase |
| PKP2 | plakophilin 2 |
| PLA2G16 | phospholipase A2, group XVI |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) |
| PLEK2 | pleckstrin 2 |
| PLN | phospholamban |
| PLS1 | plastin 1 |
| PLSCR4 | phospholipid scramblase 4 |
| PNMA2 | paraneoplastic Ma antigen 2 |
| POGZ | pogo transposable element with ZNF domain |
| PPL | periplakin |
| PPP4R2 | protein phosphatase 4, regulatory subunit 2 |
| PTER | phosphotriesterase related |
| PTGFR | prostaglandin F receptor (FP) |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTX3 | pentraxin 3, long |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
| RBL2 | retinoblastoma-like 2 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit |
| RNASE4 | ribonuclease, RNase A family, 4 |
| ROR1 | receptor tyrosine kinase-like orphan receptor 1 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 |
| S100A3 | S100 calcium binding protein A3 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SCRG1 | stimulator of chondrogenesis 1 |
| SDC3 | syndecan 3 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| SFRP4 | secreted frizzled-related protein 4 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SHOX2 | short stature homeobox 2 |
| SIK1 | salt-inducible kinase 1 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SLIT3 | slit homolog 3 (Drosophila) |
| SMAD6 | SMAD family member 6 |
| SNCAIP | synuclein, alpha interacting protein |
| SOD2 | superoxide dismutase 2, mitochondrial |
| SP1 | Sp1 transcription factor |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 |
| SPRR2B | small proline-rich protein 2B |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| STON1 | stonin 1 |
| STXBP2 | syntaxin binding protein 2 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| TCF21 | transcription factor 21 |
| TGM5 | transglutaminase 5 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TOP3B | topoisomerase (DNA) III beta |
| TP73-AS1 | TP73 antisense RNA 1 |
| TPD52 | tumor protein D52 |
| TREM1 | triggering receptor expressed on myeloid cells 1 |
| UBXN2B | UBX domain protein 2B |
| VCAM1 | vascular cell adhesion molecule 1 |
| VTN | vitronectin |
| WISP1 | WNT1 inducible signaling pathway protein 1 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZNF432 | zinc finger protein 432 |
| ZNF652 | zinc finger protein 652 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
