ATIC Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase|This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 471)
External Link https://ncbi.nlm.nih.gov/gene/471
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Genes

499 genes differentially expressed following the ATIC gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.0241515
CXCL9 chemokine (C-X-C motif) ligand 9 0.0176415
MAP7 microtubule-associated protein 7 0.016563
CXCL10 chemokine (C-X-C motif) ligand 10 0.0154498
HSPB1 heat shock 27kDa protein 1 0.0130662
HOPX HOP homeobox 0.0127119
TNS3 tensin 3 0.0120903
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 0.0119633
TSPAN13 tetraspanin 13 0.0107173
NPY1R neuropeptide Y receptor Y1 0.0106666
COPS7A COP9 signalosome subunit 7A 0.0105398
GSTA1 glutathione S-transferase alpha 1 0.0104201
CXCL11 chemokine (C-X-C motif) ligand 11 0.0103681
KRT7 keratin 7, type II 0.0103194
SLC38A1 solute carrier family 38, member 1 0.0102931
TNNT1 troponin T type 1 (skeletal, slow) 0.0101941
GPX3 glutathione peroxidase 3 0.010037
TIMP3 TIMP metallopeptidase inhibitor 3 0.00999103
NPTX2 neuronal pentraxin II 0.00984958
SGK1 serum/glucocorticoid regulated kinase 1 0.0097134
VCAM1 vascular cell adhesion molecule 1 0.00927028
FN1 fibronectin 1 0.00923562
C1QA complement component 1, q subcomponent, A chain 0.00898649
TCTA T-cell leukemia translocation altered 0.00896825
PHACTR2 phosphatase and actin regulator 2 0.00887206
CA2 carbonic anhydrase II 0.00883579
C1QB complement component 1, q subcomponent, B chain 0.00871296
TSPAN12 tetraspanin 12 0.00868751
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.00860686
KLHL41 kelch-like family member 41 0.00854238
CD36 CD36 molecule (thrombospondin receptor) 0.00835556
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 0.0081624
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A 0.00814475
MIR22HG MIR22 host gene 0.0081401
FGG fibrinogen gamma chain 0.00806522
RND3 Rho family GTPase 3 0.00800441
NOTCH2NL notch 2 N-terminal like 0.00797162
PEG10 paternally expressed 10 0.00791495
DUSP5 dual specificity phosphatase 5 0.00789916
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 0.00781922
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.00777846
OSBPL10 oxysterol binding protein-like 10 0.00763666
TSC22D2 TSC22 domain family, member 2 0.00760031
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.00758065
KLF2 Kruppel-like factor 2 0.0075386
RAP1GAP2 RAP1 GTPase activating protein 2 0.00753095
CDC34 cell division cycle 34 0.00752858
TTN titin 0.0074946
CALML5 calmodulin-like 5 0.00743806
REXO2 RNA exonuclease 2 0.0074255
IL32 interleukin 32 0.00739557
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.00739003
WDR13 WD repeat domain 13 0.00737863
CREB1 cAMP responsive element binding protein 1 0.00732324
RGS16 regulator of G-protein signaling 16 0.00731147
SPARCL1 SPARC-like 1 (hevin) 0.00730206
MAP3K7CL MAP3K7 C-terminal like 0.0072992
MB myoglobin 0.00729837
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 0.00724792
ZNF91 zinc finger protein 91 0.00722425
PXDC1 PX domain containing 1 0.00721879
HSPB8 heat shock 22kDa protein 8 0.00721412
CRIP2 cysteine-rich protein 2 0.00719353
GBP1 guanylate binding protein 1, interferon-inducible 0.00718172
PSCA prostate stem cell antigen 0.00708569
SH3BGRL SH3 domain binding glutamate-rich protein like 0.00708134
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.00696506
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 0.00689703
ENO3 enolase 3 (beta, muscle) 0.00688013
ZNF512B zinc finger protein 512B 0.00685455
DSE dermatan sulfate epimerase 0.00684597
UBA1 ubiquitin-like modifier activating enzyme 1 0.00678073
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.00677851
TGFB1 transforming growth factor, beta 1 0.0067712
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.00673653
PDGFC platelet derived growth factor C 0.00672372
CCL19 chemokine (C-C motif) ligand 19 0.00672261
IDO1 indoleamine 2,3-dioxygenase 1 0.00670532
CPB1 carboxypeptidase B1 (tissue) 0.00670136
DAPK1 death-associated protein kinase 1 0.00668434
TNNI2 troponin I type 2 (skeletal, fast) 0.00667586
TNNC1 troponin C type 1 (slow) 0.00665984
TMEM165 transmembrane protein 165 0.00660661
NPY neuropeptide Y 0.00654049
RAD23A RAD23 homolog A (S. cerevisiae) 0.00652995
NDFIP1 Nedd4 family interacting protein 1 0.00652281
MN1 meningioma (disrupted in balanced translocation) 1 0.0065195
IL18 interleukin 18 0.00651594
CKM creatine kinase, muscle 0.00648023
PCDH17 protocadherin 17 0.00647561
PTK2B protein tyrosine kinase 2 beta 0.00646422
DYNLL1 dynein, light chain, LC8-type 1 0.00642124
BAD BCL2-associated agonist of cell death 0.00641857
ORC1 origin recognition complex, subunit 1 0.0064033
MLF2 myeloid leukemia factor 2 0.00639775
KRT18 keratin 18, type I 0.00637367
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.00634232
ACTA1 actin, alpha 1, skeletal muscle 0.00632327
RFTN1 raftlin, lipid raft linker 1 0.00632115
SPRED2 sprouty-related, EVH1 domain containing 2 0.00631087
AMOTL2 angiomotin like 2 0.00630804
ABHD3 abhydrolase domain containing 3 0.00630059
HSPA1A heat shock 70kDa protein 1A 0.00629486
WASL Wiskott-Aldrich syndrome-like 0.00629094
SGCE sarcoglycan, epsilon 0.00627732
PDLIM5 PDZ and LIM domain 5 0.00627256
RGS13 regulator of G-protein signaling 13 0.006269
TFEC transcription factor EC 0.0062567
GPX1 glutathione peroxidase 1 0.00623546
EZR ezrin 0.00622483
OBSL1 obscurin-like 1 0.00621007
FABP4 fatty acid binding protein 4, adipocyte 0.00616277
MTA1 metastasis associated 1 0.00615217
USO1 USO1 vesicle transport factor 0.00615047
COL11A1 collagen, type XI, alpha 1 0.0061236
RHOB ras homolog family member B 0.00610117
MYOT myotilin 0.00609791
DGKZ diacylglycerol kinase, zeta 0.00605859
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00605431
CAPN2 calpain 2, (m/II) large subunit 0.00604816
IRAK1 interleukin-1 receptor-associated kinase 1 0.00603509
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.00599137
CTSD cathepsin D 0.00597951
CYB5A cytochrome b5 type A (microsomal) 0.00593064
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae) 0.00592403
AREG amphiregulin 0.0058958
FXYD6 FXYD domain containing ion transport regulator 6 0.00589149
ZNF160 zinc finger protein 160 0.00587341
BCAP31 B-cell receptor-associated protein 31 0.00586404
ELF4 E74-like factor 4 (ets domain transcription factor) 0.00585299
PLK2 polo-like kinase 2 0.00582833
ANXA10 annexin A10 0.00580684
APOC1 apolipoprotein C-I 0.00580668
SCAF4 SR-related CTD-associated factor 4 0.00580415
CLIC2 chloride intracellular channel 2 0.00578656
APOA1 apolipoprotein A-I 0.00578434
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.00578082
RBPMS RNA binding protein with multiple splicing 0.00576322
ABHD17A abhydrolase domain containing 17A 0.00575192
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) 0.00574499
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 0.00573906
LDOC1 leucine zipper, down-regulated in cancer 1 0.00572259
H1-2 H1.2 linker histone, cluster member 0.0057099
ARHGAP29 Rho GTPase activating protein 29 0.0056534
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 0.00562439
C10ORF10 chromosome 10 open reading frame 10 0.00561833
NUPR1 nuclear protein, transcriptional regulator, 1 0.00561296
ECM1 extracellular matrix protein 1 0.00557195
SLITRK5 SLIT and NTRK-like family, member 5 0.00554277
TNNI1 troponin I type 1 (skeletal, slow) 0.00550298
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic 0.00546133
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.00546107
SOD2 superoxide dismutase 2, mitochondrial 0.00545575
BHMT2 betaine--homocysteine S-methyltransferase 2 0.00544535
RBM47 RNA binding motif protein 47 0.00542543
CD40 CD40 molecule, TNF receptor superfamily member 5 0.00541657
NUAK1 NUAK family, SNF1-like kinase, 1 0.00541548
CP ceruloplasmin (ferroxidase) 0.00541073
HHEX hematopoietically expressed homeobox 0.005406
SNX3 sorting nexin 3 0.00539914
FHL1 four and a half LIM domains 1 0.00538776
RHOD ras homolog family member D 0.00538071
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.00537431
PON3 paraoxonase 3 0.00537074
MYOZ2 myozenin 2 0.00536798
CGA glycoprotein hormones, alpha polypeptide 0.0053656
GSAP gamma-secretase activating protein 0.00536311
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 0.00536086
CNOT7 CCR4-NOT transcription complex, subunit 7 0.00535609
EIF5 eukaryotic translation initiation factor 5 0.00535027
KRAS Kirsten rat sarcoma viral oncogene homolog 0.00534063
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.00530316
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 0.00528222
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.00527586
CRHBP corticotropin releasing hormone binding protein 0.00526982
NOTCH1 notch 1 0.00524202
RHOBTB3 Rho-related BTB domain containing 3 0.00523965
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 0.00523905
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase 0.0052388
BANP BTG3 associated nuclear protein 0.00522825
DCAF6 DDB1 and CUL4 associated factor 6 0.00522724
CLU clusterin 0.005206
MEST mesoderm specific transcript 0.00517547
EXT1 exostosin glycosyltransferase 1 0.00516158
MYL1 myosin, light chain 1, alkali; skeletal, fast 0.00514512
PLXNA2 plexin A2 0.005145
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) 0.00512148
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 0.00511315
REEP1 receptor accessory protein 1 0.00509797
KRT8 keratin 8, type II 0.00509159
PLXNC1 plexin C1 0.00509061
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 0.00507665
PEA15 phosphoprotein enriched in astrocytes 15 0.00507644
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 0.00506568
PRKCZ protein kinase C, zeta 0.00506525
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 0.00505223
P3H2 prolyl 3-hydroxylase 2 0.00505162
CADM1 cell adhesion molecule 1 0.00504982
CRIP1 cysteine-rich protein 1 (intestinal) 0.00504252
G6PD glucose-6-phosphate dehydrogenase 0.00503962
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 0.00500355
MYBPC2 myosin binding protein C, fast type 0.00498983
IL6R interleukin 6 receptor 0.00498493
TIMP1 TIMP metallopeptidase inhibitor 1 0.004984
MTCL1 microtubule crosslinking factor 1 0.00497133
UNC50 unc-50 homolog (C. elegans) 0.00495978
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.0049587
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.00495076
NADK NAD kinase 0.00494024
HSPA14 heat shock 70kDa protein 14 0.00492222
CD63 CD63 molecule 0.00491778
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 0.00490571
TENT4A terminal nucleotidyltransferase 4A 0.00489636
CRP C-reactive protein, pentraxin-related 0.00489356
PTP4A3 protein tyrosine phosphatase type IVA, member 3 0.00489067
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.00488806
ASPN asporin 0.00488716
STK26 serine/threonine protein kinase 26 0.00488072
NOTCH2 notch 2 0.00488011
PLXNB2 plexin B2 0.00487407
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2 0.00487216
CUX2 cut-like homeobox 2 0.00487082
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.00486205
CLEC3B C-type lectin domain family 3, member B 0.00486154
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 0.00484762
PRSS8 protease, serine, 8 0.00484427
TM4SF1 transmembrane 4 L six family member 1 0.00482661
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A 0.00481093
U2AF2 U2 small nuclear RNA auxiliary factor 2 0.00480863
PRMT3 protein arginine methyltransferase 3 0.00480436
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 0.00479764
FAM13A family with sequence similarity 13, member A 0.00479075
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 0.0047751
ACTN4 actinin, alpha 4 0.00477426
TMEM134 transmembrane protein 134 0.00476963
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 0.00476915
ATG101 autophagy related 101 0.00476672
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.00474861
PPAP2A phosphatidic acid phosphatase type 2A 0.00474844
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 0.00474409
LOXL1 lysyl oxidase-like 1 0.00473804
TENM3 teneurin transmembrane protein 3 0.00473612
FMO3 flavin containing monooxygenase 3 0.00473393
BMP2K BMP2 inducible kinase 0.00473089
CCL8 chemokine (C-C motif) ligand 8 0.00472924
CD164 CD164 molecule, sialomucin 0.00472813
ACTC1 actin, alpha, cardiac muscle 1 0.00471936
ATP13A3 ATPase type 13A3 0.00471739
GKN1 gastrokine 1 0.00470426
FBXW12 F-box and WD repeat domain containing 12 0.00470032

decreased expression

Symbol Name Standardized Value
LCN2 lipocalin 2 -0.0192428
CXCL5 chemokine (C-X-C motif) ligand 5 -0.014776
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.0130466
PRKCA protein kinase C, alpha -0.0126326
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.0125014
MAP2K6 mitogen-activated protein kinase kinase 6 -0.0121855
OLFM4 olfactomedin 4 -0.011844
PRAME preferentially expressed antigen in melanoma -0.0114054
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0112921
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) -0.0110211
SSBP2 single-stranded DNA binding protein 2 -0.0107237
NELL2 NEL-like 2 (chicken) -0.0105945
MMP12 matrix metallopeptidase 12 -0.0103554
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.0102351
ACTA2 actin, alpha 2, smooth muscle, aorta -0.0101302
S100A9 S100 calcium binding protein A9 -0.00958195
RCAN1 regulator of calcineurin 1 -0.00952138
MGP matrix Gla protein -0.00950072
MAL mal, T-cell differentiation protein -0.00933081
DPEP1 dipeptidase 1 (renal) -0.00915055
TMC5 transmembrane channel-like 5 -0.00912171
NTS neurotensin -0.00908878
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -0.00908345
DEFB1 defensin, beta 1 -0.00905188
IFITM1 interferon induced transmembrane protein 1 -0.00884958
NT5E 5'-nucleotidase, ecto (CD73) -0.00848944
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00845794
LRRN3 leucine rich repeat neuronal 3 -0.00845754
S100B S100 calcium binding protein B -0.00827815
ALOX5AP arachidonate 5-lipoxygenase-activating protein -0.00826379
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) -0.00824766
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -0.00816564
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -0.00814089
GPM6B glycoprotein M6B -0.00813301
PNMA8A PNMA family member 8A -0.0080935
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -0.00798746
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -0.00798241
RNASET2 ribonuclease T2 -0.00795623
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.00793394
PTGES prostaglandin E synthase -0.00790788
AOC1 amine oxidase, copper containing 1 -0.00789239
DHRS3 dehydrogenase/reductase (SDR family) member 3 -0.00786299
ATP10B ATPase, class V, type 10B -0.00784624
VCAN versican -0.00782281
TESC tescalcin -0.0077947
MUC4 mucin 4, cell surface associated -0.00773636
PTCH1 patched 1 -0.00771383
BMP4 bone morphogenetic protein 4 -0.00760339
FAR2 fatty acyl CoA reductase 2 -0.00758471
COCH cochlin -0.00755616
HOXB7 homeobox B7 -0.00754233
ERAP2 endoplasmic reticulum aminopeptidase 2 -0.00743182
MDK midkine (neurite growth-promoting factor 2) -0.00742521
IFITM2 interferon induced transmembrane protein 2 -0.00740735
ATXN1 ataxin 1 -0.00730647
ASRGL1 asparaginase like 1 -0.00726866
PI3 peptidase inhibitor 3, skin-derived -0.00726191
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -0.00721944
MX1 MX dynamin-like GTPase 1 -0.00721416
WNT5A wingless-type MMTV integration site family, member 5A -0.00719758
CEMIP cell migration inducing protein, hyaluronan binding -0.00707848
MAB21L2 mab-21-like 2 (C. elegans) -0.00707056
TREM1 triggering receptor expressed on myeloid cells 1 -0.00706654
S100A12 S100 calcium binding protein A12 -0.00706134
SRGN serglycin -0.00705782
TMX4 thioredoxin-related transmembrane protein 4 -0.00704872
IL2RG interleukin 2 receptor, gamma -0.00704434
NQO1 NAD(P)H dehydrogenase, quinone 1 -0.00701051
BHLHE41 basic helix-loop-helix family, member e41 -0.00697364
PCDH9 protocadherin 9 -0.00697058
IFI6 interferon, alpha-inducible protein 6 -0.00696518
S100A7 S100 calcium binding protein A7 -0.00696284
PLIN3 perilipin 3 -0.00691486
CFI complement factor I -0.0068769
ADD3 adducin 3 (gamma) -0.00685986
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -0.00683233
CD1A CD1a molecule -0.00681735
PSAT1 phosphoserine aminotransferase 1 -0.00680771
COL5A2 collagen, type V, alpha 2 -0.0067549
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.00673124
SLC39A4 solute carrier family 39 (zinc transporter), member 4 -0.00671087
CD48 CD48 molecule -0.00670387
CXCL3 chemokine (C-X-C motif) ligand 3 -0.00667999
CLC Charcot-Leyden crystal galectin -0.00667701
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.00666457
AKAP12 A kinase (PRKA) anchor protein 12 -0.0066312
DEFA5 defensin, alpha 5, Paneth cell-specific -0.00662041
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) -0.00660939
PAMR1 peptidase domain containing associated with muscle regeneration 1 -0.00659396
MT1X metallothionein 1X -0.00655936
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 -0.00651556
HEPH hephaestin -0.00648822
COLEC12 collectin sub-family member 12 -0.00638976
MNDA myeloid cell nuclear differentiation antigen -0.00637795
TRIM29 tripartite motif containing 29 -0.00637689
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 -0.00636908
CA12 carbonic anhydrase XII -0.00636567
SPRR3 small proline-rich protein 3 -0.00635588
PCOLCE procollagen C-endopeptidase enhancer -0.00633922
CTSZ cathepsin Z -0.00632581
LEF1 lymphoid enhancer-binding factor 1 -0.00632008
ACTG2 actin, gamma 2, smooth muscle, enteric -0.00631198
NID2 nidogen 2 (osteonidogen) -0.00629305
CLEC11A C-type lectin domain family 11, member A -0.00627395
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) -0.00626894
RNF144A ring finger protein 144A -0.00623504
IKZF1 IKAROS family zinc finger 1 (Ikaros) -0.00618468
KLK10 kallikrein-related peptidase 10 -0.00616695
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.00612688
ZNF318 zinc finger protein 318 -0.00611398
CD3E CD3e molecule, epsilon (CD3-TCR complex) -0.00608811
RAB25 RAB25, member RAS oncogene family -0.00607036
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -0.00606026
CD2 CD2 molecule -0.00605532
DEFA6 defensin, alpha 6, Paneth cell-specific -0.0060538
REG1A regenerating islet-derived 1 alpha -0.00602791
CD3D CD3d molecule, delta (CD3-TCR complex) -0.00602679
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 -0.00601805
CALB1 calbindin 1, 28kDa -0.00600048
DDIT4 DNA-damage-inducible transcript 4 -0.00598705
OSR2 odd-skipped related transciption factor 2 -0.00597108
HSP90B2P heat shock protein 90kDa beta (Grp94), member 2, pseudogene -0.00596005
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -0.00594828
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -0.00593686
CDH17 cadherin 17, LI cadherin (liver-intestine) -0.00592504
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) -0.00591994
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) -0.00591953
HLA-DRA major histocompatibility complex, class II, DR alpha -0.00590879
LY6D lymphocyte antigen 6 complex, locus D -0.00590731
MAOA monoamine oxidase A -0.00590197
MUC5B mucin 5B, oligomeric mucus/gel-forming -0.00589079
OLFML3 olfactomedin-like 3 -0.00588757
CTSG cathepsin G -0.00588642
IVNS1ABP influenza virus NS1A binding protein -0.00588088
FOXC1 forkhead box C1 -0.00588084
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 -0.00584185
CRELD2 cysteine-rich with EGF-like domains 2 -0.00583929
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) -0.00581765
ESD esterase D -0.0058074
EGR2 early growth response 2 -0.00580154
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 -0.00579424
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.00579068
SLA Src-like-adaptor -0.0057873
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.00577906
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 -0.0057781
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G -0.005775
SFRP1 secreted frizzled-related protein 1 -0.00577485
FAM171A1 family with sequence similarity 171, member A1 -0.00576097
FGF1 fibroblast growth factor 1 (acidic) -0.00574884
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) -0.00574417
BACE1 beta-site APP-cleaving enzyme 1 -0.00573728
DHRS9 dehydrogenase/reductase (SDR family) member 9 -0.00572246
CSTA cystatin A (stefin A) -0.00572
LAMP3 lysosomal-associated membrane protein 3 -0.00570885
OPHN1 oligophrenin 1 -0.00569775
WWOX WW domain containing oxidoreductase -0.00568004
CCL22 chemokine (C-C motif) ligand 22 -0.00567756
IGBP1 immunoglobulin (CD79A) binding protein 1 -0.00567615
ANXA1 annexin A1 -0.0056705
AGTPBP1 ATP/GTP binding protein 1 -0.00566852
CYFIP2 cytoplasmic FMR1 interacting protein 2 -0.005659
HOXC6 homeobox C6 -0.00565682
FABP5 fatty acid binding protein 5 (psoriasis-associated) -0.00565274
C14ORF132 chromosome 14 open reading frame 132 -0.00563856
CD1B CD1b molecule -0.00562075
GPR183 G protein-coupled receptor 183 -0.00561002
ACP6 acid phosphatase 6, lysophosphatidic -0.00559522
REG1B regenerating islet-derived 1 beta -0.00557631
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -0.00557401
BPHL biphenyl hydrolase-like (serine hydrolase) -0.00557291
STC1 stanniocalcin 1 -0.00557272
DDR2 discoidin domain receptor tyrosine kinase 2 -0.00556681
LTBP1 latent transforming growth factor beta binding protein 1 -0.00556179
CENPE centromere protein E, 312kDa -0.00554513
TMEM110 transmembrane protein 110 -0.0055132
RNASE6 ribonuclease, RNase A family, k6 -0.00550143
TUBB2B tubulin, beta 2B class IIb -0.00550126
EYA2 EYA transcriptional coactivator and phosphatase 2 -0.00549913
GCA grancalcin, EF-hand calcium binding protein -0.00549348
FERMT1 fermitin family member 1 -0.00549284
ZNF423 zinc finger protein 423 -0.00548922
BPI bactericidal/permeability-increasing protein -0.0054412
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.00543311
MMD monocyte to macrophage differentiation-associated -0.00543132
FBP1 fructose-1,6-bisphosphatase 1 -0.00543087
LAMA4 laminin, alpha 4 -0.00542842
LTF lactotransferrin -0.00542548
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.00542505
NID1 nidogen 1 -0.00542428
DDAH2 dimethylarginine dimethylaminohydrolase 2 -0.00541376
CD96 CD96 molecule -0.00541257
WFDC2 WAP four-disulfide core domain 2 -0.00540385
SERINC5 serine incorporator 5 -0.00539959
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 -0.00539584
SASH3 SAM and SH3 domain containing 3 -0.00539453
SOX10 SRY (sex determining region Y)-box 10 -0.00538585
CLTB clathrin, light chain B -0.00537481
TUBB2A tubulin, beta 2A class IIa -0.00537393
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) -0.00536286
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 -0.00535909
S100A8 S100 calcium binding protein A8 -0.00535404
MUC13 mucin 13, cell surface associated -0.00535231
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D -0.00535151
STAT5A signal transducer and activator of transcription 5A -0.00534848
RGS10 regulator of G-protein signaling 10 -0.0053347
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.00533388
CD1C CD1c molecule -0.00532121
LCK LCK proto-oncogene, Src family tyrosine kinase -0.00531566
FA2H fatty acid 2-hydroxylase -0.00531112
SPA17 sperm autoantigenic protein 17 -0.00530867
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00530449
FCGBP Fc fragment of IgG binding protein -0.00530131
RELN reelin -0.0052961
MMP10 matrix metallopeptidase 10 -0.00529299
HSPA2 heat shock 70kDa protein 2 -0.00528696
LGALS13 lectin, galactoside-binding, soluble, 13 -0.005283
SRPX sushi-repeat containing protein, X-linked -0.00527168
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -0.00527158
ARHGAP15 Rho GTPase activating protein 15 -0.00526856
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.00526574
PKP4 plakophilin 4 -0.00526235
ADK adenosine kinase -0.00525659
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 -0.00525625
LRP4 low density lipoprotein receptor-related protein 4 -0.00524526
PHOX2B paired-like homeobox 2b -0.00522728
SYT1 synaptotagmin I -0.00521409
NRN1 neuritin 1 -0.00519849
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 -0.00519253
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.00518633
LAMC2 laminin, gamma 2 -0.0051847
FRG1 FSHD region gene 1 -0.0051567
PRPF4 pre-mRNA processing factor 4 -0.00515068
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type -0.00514361
MTARC1 mitochondrial amidoxime reducing component 1 -0.00513483
TM6SF1 transmembrane 6 superfamily member 1 -0.00511621
EPS8L3 EPS8-like 3 -0.00511259
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -0.00511122
SELENBP1 selenium binding protein 1 -0.00510477
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 -0.00509347
MME membrane metallo-endopeptidase -0.00509176
SRPX2 sushi-repeat containing protein, X-linked 2 -0.00509171
SAP18 Sin3A-associated protein, 18kDa -0.00509071
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) -0.0050896
INAVA innate immunity activator -0.00508191
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.00507873
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -0.00507643
PER2 period circadian clock 2 -0.00505541
AUTS2 autism susceptibility candidate 2 -0.00505106
LAMP5 lysosomal-associated membrane protein family, member 5 -0.00505027