| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | ATM serine/threonine kinase|The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010] (NCBI Entrez Gene Database, 472) |
| External Link | https://ncbi.nlm.nih.gov/gene/472 |
| Similar Terms | |
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497 genes differentially expressed following the ATM gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.0182453 |
| MT1E | metallothionein 1E | 0.0164393 |
| MT1G | metallothionein 1G | 0.0137925 |
| MT1H | metallothionein 1H | 0.0135651 |
| MT1F | metallothionein 1F | 0.0133079 |
| LTF | lactotransferrin | 0.0130828 |
| MT1X | metallothionein 1X | 0.0127707 |
| HSPB1 | heat shock 27kDa protein 1 | 0.012735 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.0124195 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.0123673 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0121806 |
| MSMB | microseminoprotein, beta- | 0.0118016 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0116008 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.0115658 |
| S100P | S100 calcium binding protein P | 0.0115162 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0110508 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0108874 |
| LYZ | lysozyme | 0.010777 |
| MT1HL1 | metallothionein 1H-like 1 | 0.0107757 |
| CCN2 | cellular communication network factor 2 | 0.010681 |
| HOXC6 | homeobox C6 | 0.0105836 |
| FGF13 | fibroblast growth factor 13 | 0.0105392 |
| MPO | myeloperoxidase | 0.0103692 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0103572 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 0.0103407 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0102796 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0100969 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | 0.0100392 |
| CLEC11A | C-type lectin domain family 11, member A | 0.010035 |
| CHP1 | calcineurin-like EF-hand protein 1 | 0.00988997 |
| OLFM4 | olfactomedin 4 | 0.00985799 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 0.00976426 |
| MT2A | metallothionein 2A | 0.00948018 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00947144 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00933161 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00932978 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00927554 |
| XIC | X chromosome inactivation center | 0.00926957 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00916894 |
| MGP | matrix Gla protein | 0.00910961 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00900216 |
| IL6ST | interleukin 6 signal transducer | 0.00895637 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00874071 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa | 0.00872096 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00868831 |
| NANS | N-acetylneuraminic acid synthase | 0.00868122 |
| GYPC | glycophorin C (Gerbich blood group) | 0.00865658 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.00860606 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00853064 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00846831 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.00841848 |
| AQP9 | aquaporin 9 | 0.00837998 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | 0.00830243 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00828011 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.00825953 |
| TSPYL5 | TSPY-like 5 | 0.00823063 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00809189 |
| CHRDL1 | chordin-like 1 | 0.00806989 |
| OAT | ornithine aminotransferase | 0.00795167 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.00793465 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00781736 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00780603 |
| ANXA3 | annexin A3 | 0.00777983 |
| PCP4 | Purkinje cell protein 4 | 0.00774664 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00770193 |
| MXRA7 | matrix-remodelling associated 7 | 0.0076795 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00766612 |
| XK | X-linked Kx blood group | 0.00763214 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00762604 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00761893 |
| PEG3 | paternally expressed 3 | 0.00759497 |
| GTPBP8 | GTP-binding protein 8 (putative) | 0.00758918 |
| TRAPPC2 | trafficking protein particle complex 2 | 0.00756213 |
| MX1 | MX dynamin-like GTPase 1 | 0.00754083 |
| LIPT1 | lipoyltransferase 1 | 0.00751073 |
| RGS4 | regulator of G-protein signaling 4 | 0.0075105 |
| TAC1 | tachykinin, precursor 1 | 0.00751036 |
| ANXA1 | annexin A1 | 0.00750266 |
| SORD | sorbitol dehydrogenase | 0.00748213 |
| EPCAM | epithelial cell adhesion molecule | 0.00746186 |
| LBH | limb bud and heart development | 0.00743468 |
| CSTA | cystatin A (stefin A) | 0.00742068 |
| SELL | selectin L | 0.00740898 |
| ITK | IL2-inducible T-cell kinase | 0.0074062 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00737364 |
| NUP58 | nucleoporin 58 | 0.00735435 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0073412 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 | 0.00733837 |
| TMC5 | transmembrane channel-like 5 | 0.0073324 |
| SLC44A4 | solute carrier family 44, member 4 | 0.00733001 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 | 0.0073149 |
| GUCY2C | guanylate cyclase 2C | 0.00727382 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | 0.00724334 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00721867 |
| AHSP | alpha hemoglobin stabilizing protein | 0.00721257 |
| TCF7 | transcription factor 7 (T-cell specific, HMG-box) | 0.00719002 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00716462 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00714352 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | 0.00714262 |
| ACP5 | acid phosphatase 5, tartrate resistant | 0.00711978 |
| RHOB | ras homolog family member B | 0.00711707 |
| AGR2 | anterior gradient 2 | 0.00709162 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.00707853 |
| RETREG1 | reticulophagy regulator 1 | 0.00707621 |
| PSPC1 | paraspeckle component 1 | 0.00706123 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits | 0.00703669 |
| ARG2 | arginase 2 | 0.00702728 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00699376 |
| METTL7A | methyltransferase like 7A | 0.00695346 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00689211 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.00685701 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.00682651 |
| APOC1 | apolipoprotein C-I | 0.00679855 |
| WWOX | WW domain containing oxidoreductase | 0.00677296 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.00676554 |
| TSPAN31 | tetraspanin 31 | 0.00675924 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.00674672 |
| TGM2 | transglutaminase 2 | 0.00674583 |
| CPOX | coproporphyrinogen oxidase | 0.00669925 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.00669923 |
| MYO5C | myosin VC | 0.00667755 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00665866 |
| RTCA | RNA 3'-terminal phosphate cyclase | 0.00658386 |
| SEC62 | SEC62 homolog (S. cerevisiae) | 0.00658134 |
| SEC61G | Sec61 gamma subunit | 0.00657979 |
| SEPTIN6 | septin 6 | 0.00654118 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00653064 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | 0.00652322 |
| PLAUR | plasminogen activator, urokinase receptor | 0.00650198 |
| NIBAN1 | niban apoptosis regulator 1 | 0.00649586 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.00648057 |
| C6ORF48 | chromosome 6 open reading frame 48 | 0.00646972 |
| ATP5G2 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) | 0.00646026 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | 0.00645765 |
| RPS17 | ribosomal protein S17 | 0.00644217 |
| MMP12 | matrix metallopeptidase 12 | 0.00642293 |
| TMEM110 | transmembrane protein 110 | 0.00640954 |
| BPIFA1 | BPI fold containing family A, member 1 | 0.00639897 |
| FKBP14 | FK506 binding protein 14, 22 kDa | 0.00639025 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.00638148 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00636842 |
| MRPL23 | mitochondrial ribosomal protein L23 | 0.00636618 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | 0.0063556 |
| RPL36AL | ribosomal protein L36a-like | 0.00635481 |
| NPTX2 | neuronal pentraxin II | 0.0063404 |
| G0S2 | G0/G1 switch 2 | 0.00633653 |
| ZNF277 | zinc finger protein 277 | 0.00632562 |
| HOXA10 | homeobox A10 | 0.00631471 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.00631339 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | 0.00631059 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00630544 |
| GOLM1 | golgi membrane protein 1 | 0.00630422 |
| IFITM2 | interferon induced transmembrane protein 2 | 0.00629414 |
| CHPT1 | choline phosphotransferase 1 | 0.00628222 |
| RGS10 | regulator of G-protein signaling 10 | 0.0062794 |
| IL6 | interleukin 6 | 0.00627181 |
| MOB4 | MOB family member 4, phocein | 0.00626912 |
| HBB | hemoglobin, beta | 0.00626541 |
| TXNDC9 | thioredoxin domain containing 9 | 0.00626285 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.00624852 |
| ESD | esterase D | 0.00624712 |
| ZNF430 | zinc finger protein 430 | 0.00621765 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.00621609 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.00620044 |
| CERS6 | ceramide synthase 6 | 0.00619824 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.00618718 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0061796 |
| ABAT | 4-aminobutyrate aminotransferase | 0.00615691 |
| INSR | insulin receptor | 0.00610817 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | 0.00610029 |
| ALAS2 | 5'-aminolevulinate synthase 2 | 0.00608782 |
| C1ORF54 | chromosome 1 open reading frame 54 | 0.00606699 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.00606328 |
| LY75 | lymphocyte antigen 75 | 0.00602781 |
| DIXDC1 | DIX domain containing 1 | 0.00602038 |
| TMEM135 | transmembrane protein 135 | 0.00599878 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa | 0.00599573 |
| FHIT | fragile histidine triad | 0.00599476 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00599362 |
| HSPE1 | heat shock 10kDa protein 1 | 0.00598967 |
| H1-0 | H1.0 linker histone | 0.00598755 |
| RELN | reelin | 0.00598667 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.00597347 |
| PLSCR1 | phospholipid scramblase 1 | 0.00596185 |
| SH3YL1 | SH3 and SYLF domain containing 1 | 0.00594954 |
| SYT1 | synaptotagmin I | 0.00594599 |
| HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled | 0.00591091 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.00590508 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.00590196 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.00589308 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.00587285 |
| MT1M | metallothionein 1M | 0.0058712 |
| FAM46C | family with sequence similarity 46, member C | 0.00586528 |
| F5 | coagulation factor V (proaccelerin, labile factor) | 0.00582999 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.00582923 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.00582638 |
| CD38 | CD38 molecule | 0.00582585 |
| CYRIA | CYFIP related Rac1 interactor A | 0.0058183 |
| RND1 | Rho family GTPase 1 | 0.00579117 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00578866 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00578692 |
| RPS26 | ribosomal protein S26 | 0.00577033 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.00576724 |
| TXNIP | thioredoxin interacting protein | 0.00576573 |
| FAXDC2 | fatty acid hydroxylase domain containing 2 | 0.00575243 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | 0.00575115 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.00574155 |
| RAB3B | RAB3B, member RAS oncogene family | 0.00573691 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 | 0.00572863 |
| COX7B | cytochrome c oxidase subunit VIIb | 0.00572786 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.00571624 |
| HIRA | histone cell cycle regulator | 0.00570312 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.00569251 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.00569228 |
| BCL2A1 | BCL2-related protein A1 | 0.00567658 |
| GEM | GTP binding protein overexpressed in skeletal muscle | 0.00566095 |
| ATP10B | ATPase, class V, type 10B | 0.00565972 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 | 0.00565287 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.00565142 |
| ARMCX3 | armadillo repeat containing, X-linked 3 | 0.00563966 |
| PTCH1 | patched 1 | 0.00563878 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00563089 |
| SIAH2 | siah E3 ubiquitin protein ligase 2 | 0.00561749 |
| GPM6B | glycoprotein M6B | 0.00561732 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 | 0.00560245 |
| UXT | ubiquitously-expressed, prefoldin-like chaperone | 0.00559894 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | 0.00557138 |
| RAB21 | RAB21, member RAS oncogene family | 0.00557133 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.00556669 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0055552 |
| RASL11B | RAS-like, family 11, member B | 0.00554648 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | 0.00554433 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00553192 |
| STOM | stomatin | 0.00553141 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | 0.00552389 |
| PTGES | prostaglandin E synthase | 0.00551016 |
| TBC1D15 | TBC1 domain family, member 15 | 0.00550098 |
| TRIM22 | tripartite motif containing 22 | 0.00549622 |
| LSR | lipolysis stimulated lipoprotein receptor | 0.00549187 |
| ORC6 | origin recognition complex, subunit 6 | 0.00548351 |
| S100A12 | S100 calcium binding protein A12 | 0.00548138 |
| ARMT1 | acidic residue methyltransferase 1 | 0.00547078 |
| RASA4 | RAS p21 protein activator 4 | 0.00546172 |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 | 0.00546111 |
| CAPN6 | calpain 6 | 0.00545292 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00544587 |
| ELF1 | E74-like factor 1 (ets domain transcription factor) | 0.00544507 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00544244 |
| C3ORF14 | chromosome 3 open reading frame 14 | 0.00541898 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 | 0.00541562 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | -0.0236084 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.0146283 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.0129024 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.0118235 |
| ACKR3 | atypical chemokine receptor 3 | -0.0118012 |
| FST | follistatin | -0.0116787 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.0115059 |
| HTRA1 | HtrA serine peptidase 1 | -0.0112723 |
| NPR3 | natriuretic peptide receptor 3 | -0.011086 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.0109283 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0105118 |
| KRT14 | keratin 14, type I | -0.0104734 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.0104719 |
| PKM | pyruvate kinase, muscle | -0.010378 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.00999683 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00987605 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00983892 |
| KRT17 | keratin 17, type I | -0.00972137 |
| PODXL | podocalyxin-like | -0.00963007 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00953539 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.00953045 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.00945977 |
| PFKP | phosphofructokinase, platelet | -0.00941046 |
| CXADR | coxsackie virus and adenovirus receptor | -0.00913271 |
| S100A2 | S100 calcium binding protein A2 | -0.00903946 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00902948 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00892133 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00890863 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | -0.00886627 |
| ASPH | aspartate beta-hydroxylase | -0.00886504 |
| DSP | desmoplakin | -0.00884191 |
| KLK5 | kallikrein-related peptidase 5 | -0.00870402 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00859311 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00857878 |
| TSKU | tsukushi, small leucine rich proteoglycan | -0.00853751 |
| OLFML2A | olfactomedin-like 2A | -0.00848776 |
| NDRG1 | N-myc downstream regulated 1 | -0.00839091 |
| MEIS1 | Meis homeobox 1 | -0.00836937 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | -0.00836109 |
| NRCAM | neuronal cell adhesion molecule | -0.0082889 |
| EHD2 | EH-domain containing 2 | -0.00822933 |
| PPL | periplakin | -0.00813676 |
| OBSL1 | obscurin-like 1 | -0.00812637 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00808499 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00801287 |
| COL7A1 | collagen, type VII, alpha 1 | -0.00796427 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.00795306 |
| PMP22 | peripheral myelin protein 22 | -0.00792461 |
| KRT16 | keratin 16, type I | -0.00791917 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.00790753 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00788449 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.00781546 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.00781494 |
| CALML3 | calmodulin-like 3 | -0.00767428 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | -0.00764776 |
| AMDHD2 | amidohydrolase domain containing 2 | -0.00764401 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | -0.00752544 |
| EXT1 | exostosin glycosyltransferase 1 | -0.00748907 |
| AHR | aryl hydrocarbon receptor | -0.00745779 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.00745735 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.00744636 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.00740629 |
| TSPAN12 | tetraspanin 12 | -0.00730498 |
| LYPD3 | LY6/PLAUR domain containing 3 | -0.00718806 |
| TPI1 | triosephosphate isomerase 1 | -0.00714005 |
| ACLY | ATP citrate lyase | -0.00711672 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00709041 |
| CGA | glycoprotein hormones, alpha polypeptide | -0.00706071 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | -0.00701751 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00701504 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | -0.006996 |
| TSPAN3 | tetraspanin 3 | -0.00699598 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.00695869 |
| AUTS2 | autism susceptibility candidate 2 | -0.00692431 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.00692272 |
| GLO1 | glyoxalase I | -0.00686603 |
| CLEC2B | C-type lectin domain family 2, member B | -0.0068582 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -0.00678068 |
| NOTCH1 | notch 1 | -0.00677264 |
| SFN | stratifin | -0.00677004 |
| EMX2 | empty spiracles homeobox 2 | -0.00673519 |
| GPM6A | glycoprotein M6A | -0.00673506 |
| KIF1B | kinesin family member 1B | -0.0067282 |
| TYRP1 | tyrosinase-related protein 1 | -0.00669283 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.00668648 |
| TMEM45A | transmembrane protein 45A | -0.00667701 |
| DENND4B | DENN/MADD domain containing 4B | -0.00664024 |
| TUBB4B | tubulin, beta 4B class IVb | -0.00663993 |
| SYNM | synemin, intermediate filament protein | -0.0066392 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | -0.00661111 |
| HPGDS | hematopoietic prostaglandin D synthase | -0.006602 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00659824 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | -0.00659157 |
| FASN | fatty acid synthase | -0.00659 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.00657748 |
| LRP2 | low density lipoprotein receptor-related protein 2 | -0.00655566 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) | -0.00654539 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00652916 |
| SPATA20 | spermatogenesis associated 20 | -0.00647984 |
| TYMP | thymidine phosphorylase | -0.00646424 |
| NELL1 | NEL-like 1 (chicken) | -0.00645623 |
| INSM1 | insulinoma-associated 1 | -0.00645284 |
| MTCL1 | microtubule crosslinking factor 1 | -0.00642734 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00640143 |
| ENO1 | enolase 1, (alpha) | -0.00639809 |
| PAX6 | paired box 6 | -0.00639321 |
| EGR2 | early growth response 2 | -0.00637519 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00636586 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00634698 |
| CAPN15 | calpain 15 | -0.00633409 |
| CPE | carboxypeptidase E | -0.00630483 |
| CLCN3 | chloride channel, voltage-sensitive 3 | -0.00629226 |
| ANGPT1 | angiopoietin 1 | -0.00628901 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | -0.00628554 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00625564 |
| L1CAM | L1 cell adhesion molecule | -0.00623966 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.00622956 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.00621814 |
| SOWAHC | sosondowah ankyrin repeat domain family member C | -0.00620479 |
| POGK | pogo transposable element with KRAB domain | -0.00617967 |
| MYOF | myoferlin | -0.00617569 |
| KRT7 | keratin 7, type II | -0.0061619 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 | -0.00615803 |
| RCAN2 | regulator of calcineurin 2 | -0.00615649 |
| TUFT1 | tuftelin 1 | -0.00615392 |
| PAGE1 | P antigen family, member 1 (prostate associated) | -0.00612343 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -0.00610544 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.00609042 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.00608486 |
| PDGFD | platelet derived growth factor D | -0.00608032 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0060676 |
| GDI1 | GDP dissociation inhibitor 1 | -0.00605768 |
| KLK7 | kallikrein-related peptidase 7 | -0.00605363 |
| COLEC12 | collectin sub-family member 12 | -0.00605045 |
| PEG10 | paternally expressed 10 | -0.00605011 |
| SPON1 | spondin 1, extracellular matrix protein | -0.00603793 |
| KIAA0125 | KIAA0125 | -0.00602624 |
| UGT2A3 | UDP glucuronosyltransferase 2 family, polypeptide A3 | -0.00602205 |
| CDA | cytidine deaminase | -0.00600565 |
| HOPX | HOP homeobox | -0.00600556 |
| CADM1 | cell adhesion molecule 1 | -0.00600312 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00599534 |
| CNPY3 | canopy FGF signaling regulator 3 | -0.00599165 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.00598621 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.00598089 |
| FLOT1 | flotillin 1 | -0.00597892 |
| LAMA5 | laminin, alpha 5 | -0.00597754 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00597554 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -0.00595744 |
| KLHDC3 | kelch domain containing 3 | -0.00595154 |
| IGSF3 | immunoglobulin superfamily, member 3 | -0.00595031 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | -0.00591026 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.00590459 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.00586382 |
| MTCH1 | mitochondrial carrier 1 | -0.00585493 |
| NECTIN3 | nectin cell adhesion molecule 3 | -0.00584823 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00583286 |
| KRT23 | keratin 23, type I | -0.00583285 |
| TUBA4A | tubulin, alpha 4a | -0.00583247 |
| RTN2 | reticulon 2 | -0.0058216 |
| CDR2L | cerebellar degeneration-related protein 2-like | -0.00581974 |
| NNMT | nicotinamide N-methyltransferase | -0.00580796 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.00580221 |
| DSG1 | desmoglein 1 | -0.00578791 |
| TGFB1 | transforming growth factor, beta 1 | -0.00578152 |
| PERP | PERP, TP53 apoptosis effector | -0.00577669 |
| RXRA | retinoid X receptor, alpha | -0.00576815 |
| CD34 | CD34 molecule | -0.00576433 |
| ZNF395 | zinc finger protein 395 | -0.00575624 |
| HLTF | helicase-like transcription factor | -0.00575298 |
| G6PD | glucose-6-phosphate dehydrogenase | -0.00574073 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | -0.00573017 |
| E2F2 | E2F transcription factor 2 | -0.00572651 |
| ELN | elastin | -0.00571575 |
| CYB5A | cytochrome b5 type A (microsomal) | -0.00570661 |
| FOXF2 | forkhead box F2 | -0.00570636 |
| TRIB1 | tribbles pseudokinase 1 | -0.00568987 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0056843 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00568273 |
| MSRB1 | methionine sulfoxide reductase B1 | -0.00567662 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.00567609 |
| PDZK1 | PDZ domain containing 1 | -0.00565223 |
| SCGN | secretagogin, EF-hand calcium binding protein | -0.00564208 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00562841 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00561819 |
| C7ORF49 | chromosome 7 open reading frame 49 | -0.00561586 |
| DUSP2 | dual specificity phosphatase 2 | -0.00560538 |
| CBX1 | chromobox homolog 1 | -0.00560001 |
| ASPA | aspartoacylase | -0.00555989 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | -0.0055562 |
| CD9 | CD9 molecule | -0.00555088 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00554737 |
| MED20 | mediator complex subunit 20 | -0.00553476 |
| MGAT4B | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B | -0.00552515 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -0.00552059 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.00551461 |
| POSTN | periostin, osteoblast specific factor | -0.00551229 |
| PPP1R14B | protein phosphatase 1, regulatory (inhibitor) subunit 14B | -0.00549517 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00548811 |
| AGRN | agrin | -0.00548454 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | -0.00548317 |
| MTA1 | metastasis associated 1 | -0.00547608 |
| ANGPTL2 | angiopoietin-like 2 | -0.00546754 |
| SLC25A1 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | -0.00545919 |
| DIRAS2 | DIRAS family, GTP-binding RAS-like 2 | -0.00545489 |
| KYNU | kynureninase | -0.00543688 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0054262 |
| CALR | calreticulin | -0.00541851 |
| MTRR | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase | -0.005415 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.00540676 |
| CD69 | CD69 molecule | -0.00539897 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | -0.00539801 |
| CREB1 | cAMP responsive element binding protein 1 | -0.00539559 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | -0.00538938 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | -0.00538041 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.00537313 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00537045 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.00536609 |
| EPHB6 | EPH receptor B6 | -0.00535839 |
| JUND | jun D proto-oncogene | -0.00535802 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.00535199 |
| DPP4 | dipeptidyl-peptidase 4 | -0.00534358 |
| GPX3 | glutathione peroxidase 3 | -0.00534181 |
| MEA1 | male-enhanced antigen 1 | -0.00533593 |
| NVL | nuclear VCP-like | -0.00532655 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.00531622 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.00530757 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00530667 |
| S100A10 | S100 calcium binding protein A10 | -0.00530005 |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | -0.0052991 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | -0.00528518 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | -0.0052771 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.00527249 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00527184 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00526155 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00525961 |
| AURKB | aurora kinase B | -0.00525473 |
| EFNB2 | ephrin-B2 | -0.00524997 |
| GPR88 | G protein-coupled receptor 88 | -0.00524714 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | -0.0052454 |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | -0.00524181 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | -0.00523657 |
| APMAP | adipocyte plasma membrane associated protein | -0.005219 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.00521622 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00520715 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | -0.00520354 |
| TLN1 | talin 1 | -0.00519484 |
