ATN1 Gene Set

Dataset Hub Proteins Protein-Protein Interactions
Category physical interactions
Type hub protein
Description atrophin 1|Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-23 copies to 49-75 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein. [provided by RefSeq, Feb 2010] (NCBI Entrez Gene Database, 1822)
External Link http://www.ncbi.nlm.nih.gov/gene/1822
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Genes

109 interacting proteins for hub protein ATN1 from the curated Hub Proteins Protein-Protein Interactions dataset.

Symbol Name
AES amino-terminal enhancer of split
AGRN agrin
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
ARF3 ADP-ribosylation factor 3
ATN1 atrophin 1
ATRX alpha thalassemia/mental retardation syndrome X-linked
BAG6 BCL2-associated athanogene 6
BAIAP2 BAI1-associated protein 2
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CENPJ centromere protein J
CHRD chordin
CRACR2A calcium release activated channel regulator 2A
CRIP2 cysteine-rich protein 2
CSNK1E casein kinase 1, epsilon
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CTNND2 catenin (cadherin-associated protein), delta 2
DMPK dystrophia myotonica-protein kinase
DVL1 dishevelled segment polarity protein 1
DVL2 dishevelled segment polarity protein 2
ECM1 extracellular matrix protein 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EWSR1 EWS RNA-binding protein 1
FBLN1 fibulin 1
FBLN2 fibulin 2
FBLN5 fibulin 5
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GCC1 GRIP and coiled-coil domain containing 1
GIGYF1 GRB10 interacting GYF protein 1
GIGYF2 GRB10 interacting GYF protein 2
GRN granulin
GSK3B glycogen synthase kinase 3 beta
HSPG2 heparan sulfate proteoglycan 2
IRF9 interferon regulatory factor 9
ITCH itchy E3 ubiquitin protein ligase
JAG2 jagged 2
KAT6A K(lysine) acetyltransferase 6A
KAT6B K(lysine) acetyltransferase 6B
KAT7 K(lysine) acetyltransferase 7
KRT31 keratin 31, type I
KRTAP4-12 keratin associated protein 4-12
LENG8 leukocyte receptor cluster (LRC) member 8
LRP2 low density lipoprotein receptor-related protein 2
LTBP1 latent transforming growth factor beta binding protein 1
LTBP4 latent transforming growth factor beta binding protein 4
LYST lysosomal trafficking regulator
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAP7D1 MAP7 domain containing 1
MAPK1 mitogen-activated protein kinase 1
MAPK10 mitogen-activated protein kinase 10
MAPK14 mitogen-activated protein kinase 14
MAPK8 mitogen-activated protein kinase 8
MBP myelin basic protein
MDFI MyoD family inhibitor
MEGF11 multiple EGF-like-domains 11
MEGF6 multiple EGF-like-domains 6
MEGF8 multiple EGF-like-domains 8
NCK2 NCK adaptor protein 2
NELL1 NEL-like 1 (chicken)
NELL2 NEL-like 2 (chicken)
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)
NR2E1 nuclear receptor subfamily 2, group E, member 1
PCSK5 proprotein convertase subtilisin/kexin type 5
PDCD6IP programmed cell death 6 interacting protein
PFKL phosphofructokinase, liver
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLSCR1 phospholipid scramblase 1
PRRC2A proline-rich coiled-coil 2A
PRRC2B proline-rich coiled-coil 2B
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
RAD54L2 RAD54-like 2 (S. cerevisiae)
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RBM10 RNA binding motif protein 10
RBPMS RNA binding protein with multiple splicing
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RERE arginine-glutamic acid dipeptide (RE) repeats
RHOXF2 Rhox homeobox family, member 2
RNF31 ring finger protein 31
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SFPQ splicing factor proline/glutamine-rich
SIAH1 siah E3 ubiquitin protein ligase 1
SIAH2 siah E3 ubiquitin protein ligase 2
SLIT1 slit homolog 1 (Drosophila)
SPAG5 sperm associated antigen 5
SSPO SCO-spondin
STXBP4 syntaxin binding protein 4
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TEP1 telomerase-associated protein 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TRIP6 thyroid hormone receptor interactor 6
USP54 ubiquitin specific peptidase 54
VIM vimentin
WASF2 WAS protein family, member 2
WDR5 WD repeat domain 5
WWP1 WW domain containing E3 ubiquitin protein ligase 1
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZMYND8 zinc finger, MYND-type containing 8
ZNF862 zinc finger protein 862
ZSWIM8 zinc finger, SWIM-type containing 8