ATOH1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description atonal homolog 1 (Drosophila)|This protein belongs to the basic helix-loop-helix (BHLH) family of transcription factors. It activates E-box dependent transcription along with E47. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 474)
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Genes

354 genes differentially expressed following the ATOH1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 3.25892
ADTRP androgen-dependent TFPI-regulating protein 3.25892
ELSPBP1 epididymal sperm binding protein 1 3.25892
AADACL4 arylacetamide deacetylase-like 4 3.25892
HBA1 hemoglobin, alpha 1 3.25892
SLC15A5 solute carrier family 15, member 5 3.25892
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 3.25892
CSMD3 CUB and Sushi multiple domains 3 3.25892
DMRTC1B DMRT-like family C1B 3.25892
OLFM4 olfactomedin 4 3.25892
PBOV1 prostate and breast cancer overexpressed 1 3.25892
OR2B2 olfactory receptor, family 2, subfamily B, member 2 3.25892
SCGB3A1 secretoglobin, family 3A, member 1 3.25892
SLC5A9 solute carrier family 5 (sodium/sugar cotransporter), member 9 3.25892
GPR55 G protein-coupled receptor 55 3.25892
SLC26A7 solute carrier family 26 (anion exchanger), member 7 3.25892
SLC26A4 solute carrier family 26 (anion exchanger), member 4 3.25892
NPPB natriuretic peptide B 3.25892
SCN2B sodium channel, voltage gated, type II beta subunit 3.25892
SPINK1 serine peptidase inhibitor, Kazal type 1 3.25892
SPINK7 serine peptidase inhibitor, Kazal type 7 (putative) 3.25892
PRICKLE4 prickle homolog 4 (Drosophila) 3.25892
CX3CL1 chemokine (C-X3-C motif) ligand 1 3.25892
PECAM1 platelet/endothelial cell adhesion molecule 1 3.25892
TCAF2 TRPM8 channel-associated factor 2 3.25892
CRYGA crystallin, gamma A 3.25892
PTK6 protein tyrosine kinase 6 3.25892
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2 3.25892
HMX1 H6 family homeobox 1 3.25892
STAP1 signal transducing adaptor family member 1 3.25892
NR4A3 nuclear receptor subfamily 4, group A, member 3 3.25892
PCDHGA12 protocadherin gamma subfamily A, 12 3.25892
MEIG1 meiosis/spermiogenesis associated 1 3.25892
CD3D CD3d molecule, delta (CD3-TCR complex) 3.25892
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 3.25892
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit 3.25892
GNRHR gonadotropin-releasing hormone receptor 3.25892
ADGB androglobin 3.25892
CA9 carbonic anhydrase IX 3.25892
C3ORF22 chromosome 3 open reading frame 22 3.25892
KIAA2012 KIAA2012 3.25892
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 3.25892
CRX cone-rod homeobox 3.25892
APOBR apolipoprotein B receptor 3.25892
TMEM89 transmembrane protein 89 3.25892
OC90 otoconin 90 3.25892
NPIPA8 nuclear pore complex interacting protein family, member A8 3.25892
IRX1 iroquois homeobox 1 3.25892
RBM33-DT RBM33 divergent transcript 3.25892
GBP2 guanylate binding protein 2, interferon-inducible 3.25892
LTB4R2 leukotriene B4 receptor 2 3.25892
CLDN14 claudin 14 3.25892
RCVRN recoverin 3.25892
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 3.25892
SLC2A7 solute carrier family 2 (facilitated glucose transporter), member 7 3.25892
WASL-DT WASL divergent transcript 3.25892
KDM4C lysine (K)-specific demethylase 4C 3.25892
UBE2QL1 ubiquitin-conjugating enzyme E2Q family-like 1 3.25892
ZNF683 zinc finger protein 683 3.25892
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 3.25892
DERPC DERPC proline and glycine rich nuclear protein 3.25892
IRF2-DT IRF2 divergent transcript 3.25892
MINDY4B MINDY family member 4B 3.25892
H2AC19 H2A clustered histone 19 3.25892
PEAK3 PEAK family member 3 3.25892
PPDPFL pancreatic progenitor cell differentiation and proliferation factor like 3.25892
SPATA46 spermatogenesis associated 46 3.25892
RTL5 retrotransposon Gag like 5 3.25892
PLAAT2 phospholipase A and acyltransferase 2 3.25892
DEPP1 DEPP autophagy regulator 1 3.25892
PYDC5 pyrin domain containing 5 3.25892
MOV10L1 Mov10 RISC complex RNA helicase like 1 3.25892
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 3.25892
VIT vitrin 3.25892
CCDC17 coiled-coil domain containing 17 3.25892
TMIE transmembrane inner ear 3.25892
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 3.25892
PCDHA2 protocadherin alpha 2 3.25892
OR2A25 olfactory receptor, family 2, subfamily A, member 25 3.25892
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 3.25892
TMPRSS11F transmembrane protease, serine 11F 3.25892
LAPTM5 lysosomal protein transmembrane 5 3.25892
INHBC inhibin, beta C 3.25892
TRIM67 tripartite motif containing 67 3.25892
ERVFRD-1 endogenous retrovirus group FRD, member 1 3.25892
OR10AG1 olfactory receptor, family 10, subfamily AG, member 1 3.25892
TACR2 tachykinin receptor 2 3.25892
CNTFR ciliary neurotrophic factor receptor 3.25892
SBSN suprabasin 3.25892
S100P S100 calcium binding protein P 3.25892
CCR7 chemokine (C-C motif) receptor 7 3.25892
MYOT myotilin 3.25892
CFAP45 cilia and flagella associated protein 45 3.25892
OR51B2 olfactory receptor, family 51, subfamily B, member 2 (gene/pseudogene) 3.25892
IL31RA interleukin 31 receptor A 3.25892
LRRD1 leucine-rich repeats and death domain containing 1 3.25892
CGB7 chorionic gonadotropin, beta polypeptide 7 3.25892
NACA2 nascent polypeptide-associated complex alpha subunit 2 3.25892
LRRC43 leucine rich repeat containing 43 3.25892
KCNK3 potassium channel, two pore domain subfamily K, member 3 3.25892
BRDT bromodomain, testis-specific 3.25892
NIM1K NIM1 serine/threonine protein kinase 3.25892
OXGR1 oxoglutarate (alpha-ketoglutarate) receptor 1 3.25892
GP2 glycoprotein 2 (zymogen granule membrane) 3.25892
CERKL ceramide kinase-like 3.25892
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 3.25892
PCDHGB5 protocadherin gamma subfamily B, 5 3.25892
PRSS55 protease, serine, 55 3.25892
NT5C1B 5'-nucleotidase, cytosolic IB 3.25892
OTOP2 otopetrin 2 3.25892
PLA2G4E phospholipase A2, group IVE 3.25892
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 3.25892
MAGED4B melanoma antigen family D4B 3.25892
PKDREJ polycystin (PKD) family receptor for egg jelly 3.25892
FBXO39 F-box protein 39 3.25892
DKK4 dickkopf WNT signaling pathway inhibitor 4 3.25892
PCDHGA4 protocadherin gamma subfamily A, 4 3.25892
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 3.25892
THBD thrombomodulin 3.25892
VWA3A von Willebrand factor A domain containing 3A 3.25892
IL36R interleukin 36 receptor 3.25892
PSKH2 protein serine kinase H2 3.25892
MAB21L2 mab-21-like 2 (C. elegans) 3.25892
CYS1 cystin 1 3.25892
CCDC185 coiled-coil domain containing 185 3.25892
GOLGA6D golgin A6 family, member D 3.25892
DGCR6 DiGeorge syndrome critical region gene 6 3.25892
CAMKMT calmodulin-lysine N-methyltransferase 3.25892
SIRPG signal-regulatory protein gamma 3.25892
KLK7 kallikrein-related peptidase 7 3.25892
HHATL hedgehog acyltransferase-like 3.25892
SST somatostatin 3.25892
CLRN2 clarin 2 3.25892
SMIM23 small integral membrane protein 23 3.25892
EGR3 early growth response 3 3.25892
PRSS57 protease, serine, 57 3.25892
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 3.25892
NUTM2F NUT family member 2F 3.25892
POU3F3 POU class 3 homeobox 3 3.25892
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 3.25892
NPAS4 neuronal PAS domain protein 4 3.25892
CLCA4 chloride channel accessory 4 3.25892
CD8B CD8b molecule 3.25892
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 3.25892
GRAPL GRB2-related adaptor protein-like 3.25892
RGS8 regulator of G-protein signaling 8 3.25892
RNF148 ring finger protein 148 3.25892
PPP1R3G protein phosphatase 1, regulatory subunit 3G 3.25892
BTG4 B-cell translocation gene 4 3.25892
PLA2G1B phospholipase A2, group IB (pancreas) 3.25892
NXF2B nuclear RNA export factor 2B 3.25892
GCSAML germinal center-associated, signaling and motility-like 3.25892
GPR149 G protein-coupled receptor 149 3.25892
PSG3 pregnancy specific beta-1-glycoprotein 3 3.25892
LPO lactoperoxidase 3.25892
PRTN3 proteinase 3 3.25892
BCL2L15 BCL2-like 15 3.25892
NRGN neurogranin (protein kinase C substrate, RC3) 3.25892
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 3.25892
OR14A16 olfactory receptor, family 14, subfamily A, member 16 3.25892
PRR15L proline rich 15-like 3.25892
C9ORF50 chromosome 9 open reading frame 50 3.25892
CROCC2 ciliary rootlet coiled-coil, rootletin family member 2 3.25892
DYNLT2B dynein light chain Tctex-type 2B 3.21597
LDHC lactate dehydrogenase C 3.20989
DCAF12L2 DDB1 and CUL4 associated factor 12-like 2 3.20989
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 3.20989
EPHA5 EPH receptor A5 3.20989
GMFG glia maturation factor, gamma 3.20187
CNPY3 canopy FGF signaling regulator 3 3.12373
HAO2 hydroxyacid oxidase 2 (long chain) 3.0676
RET ret proto-oncogene 2.91664
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1 2.91598
HS3ST4 heparan sulfate (glucosamine) 3-O-sulfotransferase 4 2.8184
TTF2 transcription termination factor, RNA polymerase II 2.77813
TBK1 TANK-binding kinase 1 2.77561
ABHD16A abhydrolase domain containing 16A 2.75766
DNLZ DNL-type zinc finger 2.68803
NFRKB nuclear factor related to kappaB binding protein 2.68053
NRSN2 neurensin 2 2.64264
CBLC Cbl proto-oncogene C, E3 ubiquitin protein ligase 2.62986
QRFP pyroglutamylated RFamide peptide 2.57553
MED29 mediator complex subunit 29 2.5697
RPUSD2 RNA pseudouridylate synthase domain containing 2 2.5697
STAU1 staufen double-stranded RNA binding protein 1 2.53583
TTC17 tetratricopeptide repeat domain 17 2.46445
NQO1 NAD(P)H dehydrogenase, quinone 1 2.45181
RIPOR2 RHO family interacting cell polarization regulator 2 2.44242
CXCR4 chemokine (C-X-C motif) receptor 4 2.39365
EPC1 enhancer of polycomb homolog 1 (Drosophila) 2.39096
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled 2.3691
XKR3 XK, Kell blood group complex subunit-related family, member 3 2.35809
RASD1 RAS, dexamethasone-induced 1 2.34095
SIDT1 SID1 transmembrane family, member 1 2.34095
LINC02560 long intergenic non-protein coding RNA 2560 2.34095
SMTNL1 smoothelin-like 1 2.34095
ACKR3 atypical chemokine receptor 3 2.34095
TUBA8 tubulin, alpha 8 2.34095
SYCP3 synaptonemal complex protein 3 2.34095
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 2.34095
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 2.32618
GPR176 G protein-coupled receptor 176 2.29914
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6 2.29914
NOP9 NOP9 nucleolar protein 2.26074
TMEM191C transmembrane protein 191C 2.26074
TMPRSS11E transmembrane protease, serine 11E 2.26074
PARD3B par-3 family cell polarity regulator beta 2.25947
HNRNPLL heterogeneous nuclear ribonucleoprotein L-like 2.23492
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 2.20883
CEBPZOS CEBPZ opposite strand 2.20845
PMFBP1 polyamine modulated factor 1 binding protein 1 2.19698
ATF1 activating transcription factor 1 2.18394
DGLUCY D-glutamate cyclase 2.17859
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 2.17859
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 2.16532
LRR1 leucine rich repeat protein 1 2.15477
DVL3 dishevelled segment polarity protein 3 2.14377
CCDC138 coiled-coil domain containing 138 2.139
VEGFC vascular endothelial growth factor C 2.12214
NELFE negative elongation factor complex member E 2.11776
TRIR telomerase RNA component interacting RNase 2.11175
FBXL13 F-box and leucine-rich repeat protein 13 2.10189
CKAP5 cytoskeleton associated protein 5 2.08246
LYPLA1 lysophospholipase I 2.07545
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant 2.05828
CMTM8 CKLF-like MARVEL transmembrane domain containing 8 2.05165
JMJD1C jumonji domain containing 1C 2.05071
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 2.04274
KIAA0040 KIAA0040 2.04274
MYADM myeloid-associated differentiation marker 2.04274
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 2.04058
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.04058
RPLP0 ribosomal protein, large, P0 2.04058
EVL Enah/Vasp-like 2.04058
AJAP1 adherens junctions associated protein 1 2.04058
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2.0402
SLC31A1 solute carrier family 31 (copper transporter), member 1 2.03153
IAH1 isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae) 2.02698
CR1L complement component (3b/4b) receptor 1-like 2.0161
NOTCH4 notch 4 2.0025

decreased expression

Symbol Name Standardized Value
FAM110D family with sequence similarity 110, member D -3.25892
HHAT hedgehog acyltransferase -3.25892
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 -3.25892
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 -3.25892
RENBP renin binding protein -3.25892
SFXN3 sideroflexin 3 -3.25892
FCRL5 Fc receptor-like 5 -3.25892
SLC5A11 solute carrier family 5 (sodium/inositol cotransporter), member 11 -3.25892
WDR93 WD repeat domain 93 -3.25892
CDC73 cell division cycle 73 -3.25892
SLC10A4 solute carrier family 10, member 4 -3.25892
SLC4A10 solute carrier family 4, sodium bicarbonate transporter, member 10 -3.13456
OIT3 oncoprotein induced transcript 3 -3.12373
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -3.12373
DEFB134 defensin, beta 134 -3.12373
OR2A42 olfactory receptor, family 2, subfamily A, member 42 -3.12373
WNT3A wingless-type MMTV integration site family, member 3A -3.12373
LRRC56 leucine rich repeat containing 56 -3.12373
C6ORF58 chromosome 6 open reading frame 58 -3.12373
PARP15 poly (ADP-ribose) polymerase family, member 15 -3.12373
ABI3BP ABI family, member 3 (NESH) binding protein -3.12373
AHSG alpha-2-HS-glycoprotein -3.12373
CD34 CD34 molecule -3.12373
SPINT4 serine peptidase inhibitor, Kunitz type 4 -3.12373
NLRP6 NLR family, pyrin domain containing 6 -3.12373
HRH4 histamine receptor H4 -3.12373
PCDHB10 protocadherin beta 10 -3.12373
NPNT nephronectin -3.12373
MUC19 mucin 19, oligomeric -3.12373
IL5 interleukin 5 -3.12373
LMX1A LIM homeobox transcription factor 1, alpha -3.12373
KLRF1 killer cell lectin-like receptor subfamily F, member 1 -3.12373
SAMD15 sterile alpha motif domain containing 15 -3.12373
MROH5 maestro heat-like repeat family member 5 -3.12373
MYL10 myosin, light chain 10, regulatory -3.12373
CES3 carboxylesterase 3 -3.12373
LCT lactase -3.12373
CCDC13 coiled-coil domain containing 13 -3.12373
SCUBE2 signal peptide, CUB domain, EGF-like 2 -3.11051
AP5S1 adaptor-related protein complex 5, sigma 1 subunit -3.0051
CIDEB cell death-inducing DFFA-like effector b -2.98182
RPL36 ribosomal protein L36 -2.95284
BRD7 bromodomain containing 7 -2.94552
CNBD1 cyclic nucleotide binding domain containing 1 -2.91757
CORO7 coronin 7 -2.82855
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -2.81429
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -2.80792
FMO4 flavin containing monooxygenase 4 -2.77813
RUMY2 RUMY family member 2 -2.74911
STK10 serine/threonine kinase 10 -2.73129
LUC7L2 LUC7-like 2 (S. cerevisiae) -2.70087
INAFM1 InaF-motif containing 1 -2.633
CLDN15 claudin 15 -2.60143
KARS1 lysyl-tRNA synthetase 1 -2.57553
BRAT1 BRCA1-associated ATM activator 1 -2.5227
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 -2.46847
CASP6 caspase 6, apoptosis-related cysteine peptidase -2.45181
ZNF75D zinc finger protein 75D -2.44795
FBXO42 F-box protein 42 -2.43979
BTN2A1 butyrophilin, subfamily 2, member A1 -2.42562
IL18R1 interleukin 18 receptor 1 -2.4178
COL6A1 collagen, type VI, alpha 1 -2.41647
IFI16 interferon, gamma-inducible protein 16 -2.39096
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit -2.39096
SGK2 serum/glucocorticoid regulated kinase 2 -2.39096
LRRC36 leucine rich repeat containing 36 -2.39096
FSTL3 follistatin-like 3 (secreted glycoprotein) -2.36519
MAGED1 melanoma antigen family D1 -2.34095
QSOX2 quiescin Q6 sulfhydryl oxidase 2 -2.31436
HDGF hepatoma-derived growth factor -2.31282
NUP62 nucleoporin 62kDa -2.29421
PRNP prion protein -2.28256
TAFA5 TAFA chemokine like family member 5 -2.26762
PNMT phenylethanolamine N-methyltransferase -2.26748
TULP1 tubby like protein 1 -2.25746
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae) -2.19468
GOLT1B golgi transport 1B -2.19204
SLC25A42 solute carrier family 25, member 42 -2.18465
SPMIP8 sperm microtubule inner protein 8 -2.18394
GREM2 gremlin 2, DAN family BMP antagonist -2.18394
MRPL55 mitochondrial ribosomal protein L55 -2.17859
RSPH3 radial spoke 3 homolog (Chlamydomonas) -2.17387
SPTBN2 spectrin, beta, non-erythrocytic 2 -2.16532
LOC112694756 uncharaterized LOC112694756 -2.16383
CHCT1 CHD1 helical C-terminal domain containing 1 -2.16383
EFHB EF-hand domain family, member B -2.16383
RASA4 RAS p21 protein activator 4 -2.16383
ZNF70 zinc finger protein 70 -2.15784
PEX11G peroxisomal biogenesis factor 11 gamma -2.15553
IL34 interleukin 34 -2.15309
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -2.14764
DTNA dystrobrevin, alpha -2.139
SOAT1 sterol O-acyltransferase 1 -2.139
CNMD chondromodulin -2.139
TMEM205 transmembrane protein 205 -2.11779
NABP2 nucleic acid binding protein 2 -2.11776
SAYSD1 SAYSVFN motif domain containing 1 -2.11396
PRPF4 pre-mRNA processing factor 4 -2.10191
CRIPT cysteine-rich PDZ-binding protein -2.10189
AFAP1L2 actin filament associated protein 1-like 2 -2.09862
NOL9 nucleolar protein 9 -2.0789
KIAA1143 KIAA1143 -2.05795
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived) -2.05795
ZNF526 zinc finger protein 526 -2.05782
ZNF837 zinc finger protein 837 -2.04274
PTCD3 pentatricopeptide repeat domain 3 -2.04274
ZNF329 zinc finger protein 329 -2.04112
ZNF714 zinc finger protein 714 -2.02059
ACSS1 acyl-CoA synthetase short-chain family member 1 -2.0161
DNAH3 dynein, axonemal, heavy chain 3 -2.0161
FOXP2 forkhead box P2 -2.0161
ADM5 adrenomedullin 5 (putative) -2.0161
POMC proopiomelanocortin -2.0161
PLEKHD1 pleckstrin homology domain containing, family D (with coiled-coil domains) member 1 -2.0161