| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | ATR serine/threonine kinase|The protein encoded by this gene belongs the PI3/PI4-kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1, checkpoint proteins RAD17, and RAD9, as well as tumor suppressor protein BRCA1. Mutations of this gene are associated with Seckel syndrome. An alternatively spliced transcript variant of this gene has been reported, however, its full length nature is not known. Transcript variants utilizing alternative polyA sites exist. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 545) |
| External Link | https://ncbi.nlm.nih.gov/gene/545 |
| Similar Terms | |
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499 genes differentially expressed following the ATR gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.0183288 |
| GNAS | GNAS complex locus | 0.0169654 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0165588 |
| POSTN | periostin, osteoblast specific factor | 0.0163546 |
| HSPA1A | heat shock 70kDa protein 1A | 0.015864 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.0157335 |
| S100A10 | S100 calcium binding protein A10 | 0.0152321 |
| INHBA | inhibin, beta A | 0.0150857 |
| KRT19 | keratin 19, type I | 0.0141304 |
| EGR2 | early growth response 2 | 0.0129015 |
| SFN | stratifin | 0.0124693 |
| PEG10 | paternally expressed 10 | 0.0122037 |
| THBS1 | thrombospondin 1 | 0.0122001 |
| DSP | desmoplakin | 0.0117445 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0113723 |
| SFRP4 | secreted frizzled-related protein 4 | 0.0113571 |
| IPO13 | importin 13 | 0.0112715 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0111664 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0108941 |
| PERP | PERP, TP53 apoptosis effector | 0.0108638 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | 0.010855 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.0107764 |
| FN1 | fibronectin 1 | 0.0106256 |
| EMP1 | epithelial membrane protein 1 | 0.0102967 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.0102924 |
| ASPN | asporin | 0.00996903 |
| MIR22HG | MIR22 host gene | 0.00975349 |
| CCNA2 | cyclin A2 | 0.00968572 |
| KRT8 | keratin 8, type II | 0.0096711 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00924267 |
| CTSZ | cathepsin Z | 0.00922233 |
| THBS2 | thrombospondin 2 | 0.00921925 |
| GLS | glutaminase | 0.00917001 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00912776 |
| SIK1 | salt-inducible kinase 1 | 0.00908871 |
| KLF6 | Kruppel-like factor 6 | 0.00907031 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.00901346 |
| CCN2 | cellular communication network factor 2 | 0.00900533 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0088002 |
| SNAI2 | snail family zinc finger 2 | 0.00876462 |
| LPXN | leupaxin | 0.00873487 |
| PLK2 | polo-like kinase 2 | 0.00872855 |
| ELOC | elongin C | 0.0087083 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | 0.00863767 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.00862308 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00853051 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00850566 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00849061 |
| STK26 | serine/threonine protein kinase 26 | 0.00841941 |
| DUSP10 | dual specificity phosphatase 10 | 0.00841928 |
| SMAD7 | SMAD family member 7 | 0.0084098 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00831959 |
| GPX3 | glutathione peroxidase 3 | 0.00829945 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00828017 |
| COL16A1 | collagen, type XVI, alpha 1 | 0.00827513 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | 0.00824524 |
| KRT14 | keratin 14, type I | 0.00821499 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00815544 |
| TSPAN8 | tetraspanin 8 | 0.00801792 |
| C3ORF52 | chromosome 3 open reading frame 52 | 0.00798824 |
| ANKRD11 | ankyrin repeat domain 11 | 0.00797412 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.00796451 |
| AMDHD2 | amidohydrolase domain containing 2 | 0.00796117 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.00791204 |
| COMP | cartilage oligomeric matrix protein | 0.00789411 |
| MYO6 | myosin VI | 0.00788608 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00787894 |
| TGFA | transforming growth factor, alpha | 0.00787082 |
| REG1A | regenerating islet-derived 1 alpha | 0.0078051 |
| EPCAM | epithelial cell adhesion molecule | 0.00777125 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00776298 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.00774501 |
| CDA | cytidine deaminase | 0.00769706 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.00764116 |
| MAGEA3 | melanoma antigen family A3 | 0.00762271 |
| RTN4 | reticulon 4 | 0.00755616 |
| PALLD | palladin, cytoskeletal associated protein | 0.00754894 |
| RGS2 | regulator of G-protein signaling 2 | 0.00753827 |
| GPNMB | glycoprotein (transmembrane) nmb | 0.00753629 |
| ASPH | aspartate beta-hydroxylase | 0.00748503 |
| PRSS23 | protease, serine, 23 | 0.00746883 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.00746374 |
| CHP1 | calcineurin-like EF-hand protein 1 | 0.00745469 |
| MX1 | MX dynamin-like GTPase 1 | 0.00745193 |
| ZNF706 | zinc finger protein 706 | 0.00744165 |
| SC5D | sterol-C5-desaturase | 0.00743784 |
| C4BPB | complement component 4 binding protein, beta | 0.00742147 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.00741776 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | 0.00739002 |
| ODC1 | ornithine decarboxylase 1 | 0.00736692 |
| SDC2 | syndecan 2 | 0.00736537 |
| UFM1 | ubiquitin-fold modifier 1 | 0.00731294 |
| GEM | GTP binding protein overexpressed in skeletal muscle | 0.0072938 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.00728892 |
| JMJD1C | jumonji domain containing 1C | 0.00723107 |
| KCTD5 | potassium channel tetramerization domain containing 5 | 0.00721601 |
| KIF5B | kinesin family member 5B | 0.00720979 |
| YBX3 | Y box binding protein 3 | 0.00720076 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.00713266 |
| APOD | apolipoprotein D | 0.00713038 |
| LAMB1 | laminin, beta 1 | 0.00712611 |
| PKP2 | plakophilin 2 | 0.00711446 |
| PLAT | plasminogen activator, tissue | 0.00711073 |
| IMPA1 | inositol(myo)-1(or 4)-monophosphatase 1 | 0.0070717 |
| SCG5 | secretogranin V | 0.00703896 |
| MFAP5 | microfibrillar associated protein 5 | 0.00700715 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00698998 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.0069791 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.00694989 |
| HES1 | hes family bHLH transcription factor 1 | 0.00693153 |
| MATN2 | matrilin 2 | 0.00692427 |
| HOMER2 | homer scaffolding protein 2 | 0.00692409 |
| GOLGA8A | golgin A8 family, member A | 0.00687573 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.00685921 |
| JUP | junction plakoglobin | 0.00685917 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.00684281 |
| TXNRD1 | thioredoxin reductase 1 | 0.00684026 |
| PABPC3 | poly(A) binding protein, cytoplasmic 3 | 0.00682577 |
| CXADR | coxsackie virus and adenovirus receptor | 0.00681657 |
| UCHL3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) | 0.0068108 |
| GSN | gelsolin | 0.00678934 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0067847 |
| SFTPB | surfactant protein B | 0.00678414 |
| NPTN | neuroplastin | 0.006751 |
| CTSD | cathepsin D | 0.00668604 |
| NPC2 | Niemann-Pick disease, type C2 | 0.0066668 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00663903 |
| INAVA | innate immunity activator | 0.00663278 |
| SATB2 | SATB homeobox 2 | 0.00662383 |
| XIC | X chromosome inactivation center | 0.00658961 |
| AOC1 | amine oxidase, copper containing 1 | 0.00657452 |
| MOXD1 | monooxygenase, DBH-like 1 | 0.00657252 |
| SERINC5 | serine incorporator 5 | 0.00657079 |
| AFP | alpha-fetoprotein | 0.00656867 |
| MAPK6 | mitogen-activated protein kinase 6 | 0.00654687 |
| ZBTB35 | zinc finger and BTB domain containing 35 | 0.00653633 |
| CEL | carboxyl ester lipase | 0.00652805 |
| MEX3C | mex-3 RNA binding family member C | 0.00651753 |
| PHYH | phytanoyl-CoA 2-hydroxylase | 0.00649474 |
| PCNXL4 | pecanex-like 4 (Drosophila) | 0.0064924 |
| COL9A3 | collagen, type IX, alpha 3 | 0.00648835 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.00647057 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 | 0.00646648 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | 0.00646177 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 0.00644325 |
| DNM1L | dynamin 1-like | 0.00643117 |
| HDAC9 | histone deacetylase 9 | 0.00641169 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.00638899 |
| DPP4 | dipeptidyl-peptidase 4 | 0.00637756 |
| ZNF331 | zinc finger protein 331 | 0.00637233 |
| CPSF6 | cleavage and polyadenylation specific factor 6, 68kDa | 0.0063497 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | 0.00634587 |
| MXRA5 | matrix-remodelling associated 5 | 0.00634385 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | 0.00634017 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | 0.0063272 |
| MUC13 | mucin 13, cell surface associated | 0.00631661 |
| GATA6 | GATA binding protein 6 | 0.00631421 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | 0.00630457 |
| KRT16 | keratin 16, type I | 0.00629927 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.0062968 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.00629491 |
| EGR1 | early growth response 1 | 0.00629309 |
| LAMB3 | laminin, beta 3 | 0.00627192 |
| ABHD2 | abhydrolase domain containing 2 | 0.00626883 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.00626449 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.00626391 |
| TWF1 | twinfilin actin binding protein 1 | 0.0062268 |
| RUFY3 | RUN and FYVE domain containing 3 | 0.00621191 |
| TFRC | transferrin receptor | 0.00620598 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | 0.00619435 |
| CNPY3 | canopy FGF signaling regulator 3 | 0.00619128 |
| BPIFA1 | BPI fold containing family A, member 1 | 0.00618037 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.00617753 |
| MAP7 | microtubule-associated protein 7 | 0.00614612 |
| THSD7A | thrombospondin, type I, domain containing 7A | 0.00613967 |
| NVL | nuclear VCP-like | 0.00611018 |
| YBX1 | Y box binding protein 1 | 0.00610777 |
| TBC1D12 | TBC1 domain family, member 12 | 0.00610621 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.00608432 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.00608135 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.006075 |
| NELL1 | NEL-like 1 (chicken) | 0.00606997 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.00606182 |
| SFTPA2 | surfactant protein A2 | 0.00605606 |
| REC8 | REC8 meiotic recombination protein | 0.00605429 |
| GRSF1 | G-rich RNA sequence binding factor 1 | 0.00604521 |
| ANXA5 | annexin A5 | 0.00603436 |
| PFKP | phosphofructokinase, platelet | 0.0060326 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | 0.00601109 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00599549 |
| CST1 | cystatin SN | 0.00599445 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.00599111 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.00597215 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.00596686 |
| LMNA | lamin A/C | 0.00596565 |
| EVI5 | ecotropic viral integration site 5 | 0.00593643 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00593562 |
| CD1E | CD1e molecule | 0.00593542 |
| MCM2 | minichromosome maintenance complex component 2 | 0.00592989 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.00592985 |
| MTDH | metadherin | 0.00592031 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 0.0059198 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00591707 |
| GLRX | glutaredoxin (thioltransferase) | 0.00591297 |
| MAGEA12 | melanoma antigen family A12 | 0.00590769 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.00588069 |
| TMEM165 | transmembrane protein 165 | 0.00587915 |
| EIF6 | eukaryotic translation initiation factor 6 | 0.00587775 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.00586978 |
| MYO1B | myosin IB | 0.00585417 |
| HIST1H2BK | histone cluster 1, H2bk | 0.00584643 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.00583503 |
| NOTCH1 | notch 1 | 0.00582739 |
| S100A2 | S100 calcium binding protein A2 | 0.00580692 |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase | 0.00579616 |
| ABHD3 | abhydrolase domain containing 3 | 0.00577674 |
| CHKA | choline kinase alpha | 0.00576782 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.00576531 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | 0.00576356 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 | 0.00575735 |
| CYRIB | CYFIP related Rac1 interactor B | 0.00575653 |
| CD7 | CD7 molecule | 0.00575097 |
| IRS1 | insulin receptor substrate 1 | 0.00574882 |
| PDGFC | platelet derived growth factor C | 0.00573265 |
| MGAT4B | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B | 0.00572942 |
| CLTB | clathrin, light chain B | 0.00571098 |
| BRD2 | bromodomain containing 2 | 0.00570237 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | 0.00569222 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.00568224 |
| COL10A1 | collagen, type X, alpha 1 | 0.00567832 |
| IER5 | immediate early response 5 | 0.0056773 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | 0.00567116 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.00562852 |
| EPS8L2 | EPS8-like 2 | 0.00561818 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) | 0.00561808 |
| PXDC1 | PX domain containing 1 | 0.00561609 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.0056154 |
| NEU1 | sialidase 1 (lysosomal sialidase) | 0.00561475 |
| TVP23B | trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) | 0.00561308 |
| UBE2V2 | ubiquitin-conjugating enzyme E2 variant 2 | 0.0056127 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.00560322 |
| PRELID3B | PRELI domain containing 3B | 0.00559799 |
| MEST | mesoderm specific transcript | 0.00558505 |
| FUBP3 | far upstream element (FUSE) binding protein 3 | 0.00558173 |
| COX17 | COX17 cytochrome c oxidase copper chaperone | 0.00558172 |
| PDE4DIP | phosphodiesterase 4D interacting protein | 0.00558034 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | 0.00557792 |
| AACS | acetoacetyl-CoA synthetase | 0.00557118 |
| LSR | lipolysis stimulated lipoprotein receptor | 0.00555777 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CLU | clusterin | -0.0287362 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.0220775 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0186676 |
| S100A8 | S100 calcium binding protein A8 | -0.0186183 |
| LTF | lactotransferrin | -0.0179302 |
| HBB | hemoglobin, beta | -0.017002 |
| STOM | stomatin | -0.0163347 |
| S100A9 | S100 calcium binding protein A9 | -0.0154122 |
| AQP1 | aquaporin 1 (Colton blood group) | -0.0145656 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.0133827 |
| RNF167 | ring finger protein 167 | -0.0133631 |
| OLFM1 | olfactomedin 1 | -0.0127016 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0123587 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.0120632 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0119954 |
| NTS | neurotensin | -0.0119676 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.0115285 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.0115191 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | -0.0113791 |
| NRN1 | neuritin 1 | -0.0112951 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0111826 |
| MT1E | metallothionein 1E | -0.0107902 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.0107575 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.0104795 |
| CSTA | cystatin A (stefin A) | -0.0104754 |
| CFD | complement factor D (adipsin) | -0.0104556 |
| ELANE | elastase, neutrophil expressed | -0.0103898 |
| VWF | von Willebrand factor | -0.010314 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0102997 |
| ZNF395 | zinc finger protein 395 | -0.0102073 |
| GRB7 | growth factor receptor-bound protein 7 | -0.010195 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | -0.010108 |
| MT1G | metallothionein 1G | -0.00997489 |
| EREG | epiregulin | -0.00978685 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00975277 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | -0.00968311 |
| GLUL | glutamate-ammonia ligase | -0.00965476 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.0096509 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00955218 |
| GPM6B | glycoprotein M6B | -0.00945971 |
| CST7 | cystatin F (leukocystatin) | -0.00940047 |
| CAV2 | caveolin 2 | -0.0093536 |
| CLC | Charcot-Leyden crystal galectin | -0.00934303 |
| ADIRF | adipogenesis regulatory factor | -0.00926683 |
| S100P | S100 calcium binding protein P | -0.00923986 |
| MNDA | myeloid cell nuclear differentiation antigen | -0.00923204 |
| ARG1 | arginase 1 | -0.00922975 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00922729 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00922646 |
| LAPTM5 | lysosomal protein transmembrane 5 | -0.00912515 |
| RAB13 | RAB13, member RAS oncogene family | -0.00912062 |
| MT1F | metallothionein 1F | -0.00910983 |
| S100A12 | S100 calcium binding protein A12 | -0.00909578 |
| KAZN | kazrin, periplakin interacting protein | -0.00907643 |
| METTL7A | methyltransferase like 7A | -0.00895088 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00891537 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | -0.00888123 |
| LRRC17 | leucine rich repeat containing 17 | -0.0088432 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | -0.00880666 |
| CTSG | cathepsin G | -0.00880433 |
| ALOX5 | arachidonate 5-lipoxygenase | -0.00877584 |
| AQP9 | aquaporin 9 | -0.00869901 |
| SELL | selectin L | -0.00865622 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.00864176 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | -0.00856525 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.00852717 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | -0.00851924 |
| SRGN | serglycin | -0.00851388 |
| FTO | fat mass and obesity associated | -0.00843485 |
| RNASE3 | ribonuclease, RNase A family, 3 | -0.00841839 |
| LYZ | lysozyme | -0.0081496 |
| MSX1 | msh homeobox 1 | -0.00812732 |
| RHOB | ras homolog family member B | -0.0081238 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.00810974 |
| COL1A2 | collagen, type I, alpha 2 | -0.00809008 |
| MT1H | metallothionein 1H | -0.00807137 |
| SCARA3 | scavenger receptor class A, member 3 | -0.00806548 |
| CCNF | cyclin F | -0.00796424 |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | -0.00788902 |
| S100A7 | S100 calcium binding protein A7 | -0.00788077 |
| MT1X | metallothionein 1X | -0.00785146 |
| C1ORF115 | chromosome 1 open reading frame 115 | -0.00783397 |
| PTGES | prostaglandin E synthase | -0.00782253 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | -0.00779767 |
| B3GNT1 | -0.00777439 | |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | -0.00775476 |
| GIMAP4 | GTPase, IMAP family member 4 | -0.00771062 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.00767022 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00766229 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | -0.00763885 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.00763493 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.00761644 |
| HAL | histidine ammonia-lyase | -0.00760305 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00755315 |
| CLCA2 | chloride channel accessory 2 | -0.00753096 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.00749895 |
| AK4 | adenylate kinase 4 | -0.00749557 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.0074726 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00745802 |
| LYVE1 | lymphatic vessel endothelial hyaluronan receptor 1 | -0.00739793 |
| MT1HL1 | metallothionein 1H-like 1 | -0.00739065 |
| BEX1 | brain expressed, X-linked 1 | -0.00738614 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -0.00731957 |
| RCAN1 | regulator of calcineurin 1 | -0.00731715 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.00731668 |
| ATP5PD | ATP synthase peripheral stalk subunit d | -0.00729864 |
| GANAB | glucosidase, alpha; neutral AB | -0.00726284 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | -0.00724921 |
| DCXR | dicarbonyl/L-xylulose reductase | -0.0071856 |
| SHCBP1 | SHC SH2-domain binding protein 1 | -0.00717281 |
| FKBP14 | FK506 binding protein 14, 22 kDa | -0.0071623 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.0071142 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa | -0.00711012 |
| IL33 | interleukin 33 | -0.00707239 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | -0.00702638 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | -0.00700327 |
| NDRG3 | NDRG family member 3 | -0.00698167 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.006975 |
| CA2 | carbonic anhydrase II | -0.00697285 |
| ECHDC2 | enoyl CoA hydratase domain containing 2 | -0.00695228 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.00695178 |
| RNASET2 | ribonuclease T2 | -0.00691766 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.00691674 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.00691293 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00684187 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00684076 |
| GYPC | glycophorin C (Gerbich blood group) | -0.00682593 |
| CBR3 | carbonyl reductase 3 | -0.00680615 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00676719 |
| PSAT1 | phosphoserine aminotransferase 1 | -0.00675909 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | -0.00675265 |
| GPM6A | glycoprotein M6A | -0.00674546 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | -0.00673011 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.00669388 |
| RHOH | ras homolog family member H | -0.00669276 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | -0.00666452 |
| SAP30 | Sin3A-associated protein, 30kDa | -0.00666311 |
| HBD | hemoglobin, delta | -0.00666005 |
| NGRN | neugrin, neurite outgrowth associated | -0.00663198 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -0.00662594 |
| TMEM47 | transmembrane protein 47 | -0.00662521 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.00662433 |
| RNF187 | ring finger protein 187 | -0.00662356 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00661325 |
| NIPSNAP1 | nipsnap homolog 1 (C. elegans) | -0.00659855 |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C | -0.0065893 |
| MT1M | metallothionein 1M | -0.00658185 |
| CST3 | cystatin C | -0.00656888 |
| RETREG3 | reticulophagy regulator family member 3 | -0.00654287 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.00652309 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.00651387 |
| PLEK | pleckstrin | -0.00649505 |
| CHN1 | chimerin 1 | -0.00649493 |
| C8ORF33 | chromosome 8 open reading frame 33 | -0.00649044 |
| PGAP3 | post-GPI attachment to proteins 3 | -0.00646739 |
| CBX7 | chromobox homolog 7 | -0.00646396 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.00645831 |
| TEAD4 | TEA domain family member 4 | -0.0064497 |
| SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 | -0.006394 |
| ERGIC3 | ERGIC and golgi 3 | -0.00638962 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.00637954 |
| ADD3 | adducin 3 (gamma) | -0.00637048 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | -0.00636954 |
| SLC25A11 | solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 | -0.00636089 |
| LDB2 | LIM domain binding 2 | -0.00634861 |
| SPC25 | SPC25, NDC80 kinetochore complex component | -0.00633754 |
| NRIP3 | nuclear receptor interacting protein 3 | -0.00632727 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | -0.00630165 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.00628489 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00628473 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.00628344 |
| MXI1 | MAX interactor 1, dimerization protein | -0.00626593 |
| XK | X-linked Kx blood group | -0.00625273 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00624569 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.00622151 |
| MT2A | metallothionein 2A | -0.00621502 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00620394 |
| TOR3A | torsin family 3, member A | -0.0061925 |
| C1QB | complement component 1, q subcomponent, B chain | -0.00616093 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.00615871 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | -0.00615114 |
| ERLIN2 | ER lipid raft associated 2 | -0.00612103 |
| LAGE3 | L antigen family, member 3 | -0.00609364 |
| LST1 | leukocyte specific transcript 1 | -0.0060564 |
| MMRN1 | multimerin 1 | -0.00604226 |
| PSMB6 | proteasome (prosome, macropain) subunit, beta type, 6 | -0.00602378 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00598904 |
| GUCY2C | guanylate cyclase 2C | -0.00598726 |
| FPR1 | formyl peptide receptor 1 | -0.00598235 |
| COMT | catechol-O-methyltransferase | -0.00598153 |
| OGFOD1 | 2-oxoglutarate and iron-dependent oxygenase domain containing 1 | -0.00597699 |
| HDAC6 | histone deacetylase 6 | -0.00596673 |
| HMGN5 | high mobility group nucleosome binding domain 5 | -0.00593756 |
| AZU1 | azurocidin 1 | -0.00592994 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | -0.00592858 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00590953 |
| PF4 | platelet factor 4 | -0.00590867 |
| DGLUCY | D-glutamate cyclase | -0.00589886 |
| DEXI | Dexi homolog (mouse) | -0.0058966 |
| PON2 | paraoxonase 2 | -0.00589614 |
| OPHN1 | oligophrenin 1 | -0.0058871 |
| RHOT1 | ras homolog family member T1 | -0.00587124 |
| ZNF652 | zinc finger protein 652 | -0.00585481 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.00585035 |
| MRPL40 | mitochondrial ribosomal protein L40 | -0.00584531 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | -0.00583738 |
| S1PR1 | sphingosine-1-phosphate receptor 1 | -0.00582792 |
| MRPL58 | mitochondrial ribosomal protein L58 | -0.005826 |
| PRTN3 | proteinase 3 | -0.00582092 |
| PLPBP | pyridoxal phosphate binding protein | -0.00579436 |
| SYBU | syntabulin (syntaxin-interacting) | -0.00578934 |
| HELLS | helicase, lymphoid-specific | -0.00578433 |
| NPL | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) | -0.0057748 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.005761 |
| CHI3L2 | chitinase 3-like 2 | -0.00574279 |
| BCL2A1 | BCL2-related protein A1 | -0.00572808 |
| NEBL | nebulette | -0.00572478 |
| C10ORF10 | chromosome 10 open reading frame 10 | -0.00572316 |
| BDH2 | 3-hydroxybutyrate dehydrogenase, type 2 | -0.00572201 |
| MID1 | midline 1 | -0.00570685 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.00569567 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.00568991 |
| RDX | radixin | -0.00568953 |
| TLR2 | toll-like receptor 2 | -0.0056863 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -0.00568018 |
| PRPF8 | pre-mRNA processing factor 8 | -0.00564658 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.00564654 |
| FAM107A | family with sequence similarity 107, member A | -0.005626 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | -0.00562218 |
| BTN3A2 | butyrophilin, subfamily 3, member A2 | -0.00560647 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) | -0.0055789 |
| PFN1 | profilin 1 | -0.00556301 |
| SORD | sorbitol dehydrogenase | -0.00555172 |
| EIF4B | eukaryotic translation initiation factor 4B | -0.00554268 |
| LIG1 | ligase I, DNA, ATP-dependent | -0.00553389 |
| DIO2 | deiodinase, iodothyronine, type II | -0.00552882 |
| PHB | prohibitin | -0.00552808 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | -0.00551249 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0055034 |
| IL15 | interleukin 15 | -0.00550125 |
| BTN3A1 | butyrophilin, subfamily 3, member A1 | -0.00549314 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.00549209 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00548862 |
| ZNF274 | zinc finger protein 274 | -0.00548282 |
| COL3A1 | collagen, type III, alpha 1 | -0.00548005 |
| MRTFB | myocardin related transcription factor B | -0.00547805 |
| FGF13 | fibroblast growth factor 13 | -0.00546139 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | -0.00546029 |
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | -0.00545429 |
| KLK8 | kallikrein-related peptidase 8 | -0.00543345 |
