AURA Gene Set

Dataset Kinase Library Serine Threonine Kinome Atlas
Category proteomics
Type kinase
Description aurora kinase A|The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6790)
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100 substrates of the kinase AURA from the Kinase Library Serine Threonine Kinome Atlas dataset.

Symbol Name Standardized Value
PTGER4 prostaglandin E receptor 4 (subtype EP4)
MYBPC3 myosin binding protein C, cardiac
TNNI3 troponin I type 3 (cardiac)
KIAA1671 KIAA1671
CD163L1 CD163 molecule-like 1
SACK1H scaffolding CK1 anchoring protein H
SEPT1 septin 1
PARP8 poly (ADP-ribose) polymerase family, member 8
ARID3A AT rich interactive domain 3A (BRIGHT-like)
GOLGA3 golgin A3
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
RRAD Ras-related associated with diabetes
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11
SGPP1 sphingosine-1-phosphate phosphatase 1
SENP6 SUMO1/sentrin specific peptidase 6
TRA2A transformer 2 alpha homolog (Drosophila)
MYD88 myeloid differentiation primary response 88
ARHGAP11A Rho GTPase activating protein 11A
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
TTN titin
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
OSBPL5 oxysterol binding protein-like 5
FAM65B family with sequence similarity 65, member B
KDM3B lysine (K)-specific demethylase 3B
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SETX senataxin
PBRM1 polybromo 1
KIFAP3 kinesin-associated protein 3
GCSAM germinal center-associated, signaling and motility
TBC1D30 TBC1 domain family, member 30
LAT linker for activation of T cells
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
PDE4A phosphodiesterase 4A, cAMP-specific
PDE4B phosphodiesterase 4B, cAMP-specific
PDE4C phosphodiesterase 4C, cAMP-specific
XRN2 5'-3' exoribonuclease 2
RASAL3 RAS protein activator like 3
RNF25 ring finger protein 25
ATR ATR serine/threonine kinase
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
ACTL8 actin-like 8
ASPHD1 aspartate beta-hydroxylase domain containing 1
STAR steroidogenic acute regulatory protein
RAB11FIP5 RAB11 family interacting protein 5 (class I)
PRKCA protein kinase C, alpha
ARID4A AT rich interactive domain 4A (RBP1-like)
DGUOK deoxyguanosine kinase
DMXL1 Dmx-like 1
PDE4D phosphodiesterase 4D, cAMP-specific
BCLAF1 BCL2-associated transcription factor 1
BAIAP2L2 BAI1-associated protein 2-like 2
SALL3 spalt-like transcription factor 3
GRK7 G protein-coupled receptor kinase 7
VANGL1 VANGL planar cell polarity protein 1
DENND4A DENN/MADD domain containing 4A
FAM214B family with sequence similarity 214, member B
CLK3 CDC-like kinase 3
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
IRF2BP2 interferon regulatory factor 2 binding protein 2
IRF2BPL interferon regulatory factor 2 binding protein-like
TMEM131 transmembrane protein 131
LMOD1 leiomodin 1 (smooth muscle)
AEBP2 AE binding protein 2
EPB41L2 erythrocyte membrane protein band 4.1-like 2
ABLIM3 actin binding LIM protein family, member 3
SLK STE20-like kinase
CEP128 centrosomal protein 128kDa
FCHSD2 FCH and double SH3 domains 2
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
PPHLN1 periphilin 1
CDCA2 cell division cycle associated 2
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
IL1A interleukin 1, alpha
PUM2 pumilio RNA-binding family member 2
PUM1 pumilio RNA-binding family member 1
MYO1E myosin IE
MYO10 myosin X
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
CHD2 chromodomain helicase DNA binding protein 2
CDK13 cyclin-dependent kinase 13
CDK17 cyclin-dependent kinase 17
SPEG SPEG complex locus
NES nestin
TNS1 tensin 1
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
MYO1F myosin IF
DENND4C DENN/MADD domain containing 4C
NUMA1 nuclear mitotic apparatus protein 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
CDC25B cell division cycle 25B
PYGL phosphorylase, glycogen, liver
PYGM phosphorylase, glycogen, muscle
KIF1C kinesin family member 1C
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
RBM15B RNA binding motif protein 15B
ZFR zinc finger RNA binding protein
MAP3K2 mitogen-activated protein kinase kinase kinase 2
SETD2 SET domain containing 2
MKI67 marker of proliferation Ki-67