AURKB Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description aurora kinase B|This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2013] (NCBI Entrez Gene Database, 9212)
External Link http://www.ncbi.nlm.nih.gov/gene/9212
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Genes

77 substrates of the kinase AURKB from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
AHNAK AHNAK nucleoprotein
ARHGAP21 Rho GTPase activating protein 21
ATM ATM serine/threonine kinase
ATXN10 ataxin 10
AURKB aurora kinase B
BIRC5 baculoviral IAP repeat containing 5
CASC5 cancer susceptibility candidate 5
CBX5 chromobox homolog 5
CCDC86 coiled-coil domain containing 86
CDCA2 cell division cycle associated 2
CDCA5 cell division cycle associated 5
CDCA8 cell division cycle associated 8
CENPA centromere protein A
CHMP4C charged multivesicular body protein 4C
CKAP2 cytoskeleton associated protein 2
COBLL1 cordon-bleu WH2 repeat protein-like 1
DDA1 DET1 and DDB1 associated 1
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
DEK DEK proto-oncogene
DES desmin
DIAPH2 diaphanous-related formin 2
DSN1 DSN1, MIS12 kinetochore complex component
GFAP glial fibrillary acidic protein
H3F3A H3 histone, family 3A
H3F3B H3 histone, family 3B (H3.3B)
HDAC5 histone deacetylase 5
HIST1H2BB histone cluster 1, H2bb
HIST1H3A histone cluster 1, H3a
HMGN2 high mobility group nucleosomal binding domain 2
HMGN5 high mobility group nucleosome binding domain 5
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
INCENP inner centromere protein antigens 135/155kDa
KIF23 kinesin family member 23
KIF2C kinesin family member 2C
KIF4A kinesin family member 4A
KRT8 keratin 8, type II
LMO7 LIM domain 7
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MISP mitotic spindle positioning
MKI67 marker of proliferation Ki-67
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
MYBBP1A MYB binding protein (P160) 1a
MYL12B myosin, light chain 12B, regulatory
NAGK N-acetylglucosamine kinase
NDC80 NDC80 kinetochore complex component
NELFE negative elongation factor complex member E
NINL ninein-like
NSUN2 NOP2/Sun RNA methyltransferase family, member 2
NUMA1 nuclear mitotic apparatus protein 1
NUSAP1 nucleolar and spindle associated protein 1
PARD3 par-3 family cell polarity regulator
PLEC plectin
PPHLN1 periphilin 1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTRF polymerase I and transcript release factor
RACGAP1 Rac GTPase activating protein 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RB1 retinoblastoma 1
RBM14 RNA binding motif protein 14
RBM3 RNA binding motif (RNP1, RRM) protein 3
RBMX RNA binding motif protein, X-linked
RIF1 replication timing regulatory factor 1
RPL21 ribosomal protein L21
RPL8 ribosomal protein L8
RPS10 ribosomal protein S10
SEPT1 septin 1
SH2D4A SH2 domain containing 4A
SHCBP1 SHC SH2-domain binding protein 1
SSH3 slingshot protein phosphatase 3
SSU72 SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae)
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae)
TP53 tumor protein p53
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
VIM vimentin
WWC1 WW and C2 domain containing 1
YY1 YY1 transcription factor