AXIN-APC-betaCatenin-GSK3B complex Gene Set

Dataset CORUM Protein Complexes
Category structural or functional annotations
Type protein complex
Description A cytoplasmic protein complex containing glycogen synthase kinase-3-beta (GSK-3-beta), the adenomatous polyposis coli protein (APC), and the scaffolding protein axin, among others; phosphorylates beta-catenin, targets it for degradation by the proteasome. (Gene Ontology, GO_0030877)
External Link http://mips.helmholtz-muenchen.de/genre/proj/corum/complexdetails.html?id=3166
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Genes

4 proteins in the AXIN-APC-betaCatenin-GSK3B complex protein complex from the CORUM Protein Complexes dataset.

Symbol Name
APC adenomatous polyposis coli
AXIN1 axin 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
GSK3B glycogen synthase kinase 3 beta