| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | axin 1|This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2010] (NCBI Entrez Gene Database, 8312) |
| External Link | https://ncbi.nlm.nih.gov/gene/8312 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the AXIN1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LTF | lactotransferrin | 0.0131377 |
| RGCC | regulator of cell cycle | 0.0114885 |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.00927222 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.00915942 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00883106 |
| EREG | epiregulin | 0.00880826 |
| GOLT1B | golgi transport 1B | 0.00836186 |
| SPON1 | spondin 1, extracellular matrix protein | 0.00824093 |
| CLU | clusterin | 0.00809419 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00790213 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00718134 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | 0.00713363 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.00708796 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.00706775 |
| VWF | von Willebrand factor | 0.0070268 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.00701812 |
| KRT18 | keratin 18, type I | 0.0069361 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.0069012 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.006865 |
| RHOB | ras homolog family member B | 0.00685628 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | 0.00684046 |
| EFNB2 | ephrin-B2 | 0.00682852 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.00679274 |
| NLRP2 | NLR family, pyrin domain containing 2 | 0.00677286 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.00675432 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 | 0.00673477 |
| LXN | latexin | 0.00669249 |
| ACP5 | acid phosphatase 5, tartrate resistant | 0.00657525 |
| RNF167 | ring finger protein 167 | 0.00651387 |
| XIC | X chromosome inactivation center | 0.00645255 |
| SLC25A46 | solute carrier family 25, member 46 | 0.00644393 |
| C1QA | complement component 1, q subcomponent, A chain | 0.00643114 |
| TUBB6 | tubulin, beta 6 class V | 0.00633918 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 0.00633527 |
| TGM2 | transglutaminase 2 | 0.00623219 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.00619605 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.00618242 |
| CA2 | carbonic anhydrase II | 0.00618121 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.00612247 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00605832 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00604975 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00599994 |
| LRRC17 | leucine rich repeat containing 17 | 0.0059382 |
| SLC25A4 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | 0.00593305 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.00586203 |
| KLK6 | kallikrein-related peptidase 6 | 0.00584979 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.00583578 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00581193 |
| PDZD2 | PDZ domain containing 2 | 0.00576947 |
| GPR137B | G protein-coupled receptor 137B | 0.00572887 |
| MLF1 | myeloid leukemia factor 1 | 0.00570748 |
| MAMLD1 | mastermind-like domain containing 1 | 0.00562092 |
| GIMAP6 | GTPase, IMAP family member 6 | 0.00559043 |
| CYBRD1 | cytochrome b reductase 1 | 0.00556072 |
| MED21 | mediator complex subunit 21 | 0.00555966 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | 0.0054921 |
| MSMB | microseminoprotein, beta- | 0.00548942 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | 0.00547387 |
| ZBED2 | zinc finger, BED-type containing 2 | 0.00547183 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.00546243 |
| RRM2 | ribonucleotide reductase M2 | 0.0054199 |
| MLPH | melanophilin | 0.00541666 |
| ADIRF | adipogenesis regulatory factor | 0.00538334 |
| SST | somatostatin | 0.00537227 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00535882 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | 0.00534866 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.00534227 |
| HOXB2 | homeobox B2 | 0.00532298 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.00528961 |
| CENPU | centromere protein U | 0.00528156 |
| LYPD1 | LY6/PLAUR domain containing 1 | 0.00525916 |
| KLK5 | kallikrein-related peptidase 5 | 0.00525613 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | 0.00522011 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00519679 |
| FABP6 | fatty acid binding protein 6, ileal | 0.00517728 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.00515584 |
| PDAP1 | PDGFA associated protein 1 | 0.00514661 |
| PHGDH | phosphoglycerate dehydrogenase | 0.00513019 |
| BTG3 | BTG family, member 3 | 0.00512861 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00511889 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00511469 |
| ASS1 | argininosuccinate synthase 1 | 0.00511139 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | 0.00508416 |
| PAGE4 | P antigen family, member 4 (prostate associated) | 0.00507877 |
| TARP | TCR gamma alternate reading frame protein | 0.00505869 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.00505176 |
| NTAQ1 | N-terminal glutamine amidase 1 | 0.00504804 |
| HDGFL3 | HDGF like 3 | 0.00504498 |
| IFRD2 | interferon-related developmental regulator 2 | 0.00502832 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | 0.00502216 |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | 0.00502044 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | 0.0050137 |
| STMN1 | stathmin 1 | 0.00501225 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.00499442 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.00498925 |
| GEMIN6 | gem (nuclear organelle) associated protein 6 | 0.00497001 |
| SNX10 | sorting nexin 10 | 0.00496049 |
| PLAT | plasminogen activator, tissue | 0.0049576 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.00493231 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | 0.00492515 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.00488144 |
| AADAC | arylacetamide deacetylase | 0.00487425 |
| MRPL40 | mitochondrial ribosomal protein L40 | 0.00485905 |
| RNASE6 | ribonuclease, RNase A family, k6 | 0.00484879 |
| FOLR1 | folate receptor 1 (adult) | 0.00482393 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.00482357 |
| EMX2 | empty spiracles homeobox 2 | 0.00480303 |
| TTK | TTK protein kinase | 0.00479228 |
| TPM2 | tropomyosin 2 (beta) | 0.00475733 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.00474123 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | 0.00473875 |
| PLK2 | polo-like kinase 2 | 0.00473455 |
| IQCG | IQ motif containing G | 0.0047343 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) | 0.00472586 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.00469807 |
| MSMO1 | methylsterol monooxygenase 1 | 0.00468886 |
| EGFL6 | EGF-like-domain, multiple 6 | 0.00468711 |
| PALMD | palmdelphin | 0.00468174 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00467194 |
| RGS1 | regulator of G-protein signaling 1 | 0.00466169 |
| CAV2 | caveolin 2 | 0.00465822 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.00464049 |
| PRPS1 | phosphoribosyl pyrophosphate synthetase 1 | 0.00463364 |
| CD69 | CD69 molecule | 0.00463182 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 0.00462722 |
| KLF9 | Kruppel-like factor 9 | 0.00460138 |
| RAB13 | RAB13, member RAS oncogene family | 0.00460079 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.00458816 |
| GPC4 | glypican 4 | 0.00458518 |
| MLF2 | myeloid leukemia factor 2 | 0.00458422 |
| ZNF395 | zinc finger protein 395 | 0.00457989 |
| ABHD6 | abhydrolase domain containing 6 | 0.00457521 |
| DNM1L | dynamin 1-like | 0.00455217 |
| MAGED1 | melanoma antigen family D1 | 0.00453871 |
| HRASLS | HRAS-like suppressor | 0.00453684 |
| GIMAP4 | GTPase, IMAP family member 4 | 0.00453603 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00453499 |
| NDUFA8 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa | 0.00452995 |
| GMPR | guanosine monophosphate reductase | 0.00452975 |
| PRPF4 | pre-mRNA processing factor 4 | 0.0045117 |
| MOSPD1 | motile sperm domain containing 1 | 0.00450815 |
| FOSL2 | FOS-like antigen 2 | 0.00449045 |
| VAMP7 | vesicle-associated membrane protein 7 | 0.00448587 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | 0.00447979 |
| MAGEH1 | melanoma antigen family H1 | 0.00446712 |
| CCNA2 | cyclin A2 | 0.00445685 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | 0.00444967 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00444542 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.0044454 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.00443905 |
| SORT1 | sortilin 1 | 0.00443809 |
| C3ORF14 | chromosome 3 open reading frame 14 | 0.00442867 |
| DEPDC1 | DEP domain containing 1 | 0.00441822 |
| KLK8 | kallikrein-related peptidase 8 | 0.00441587 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.00440101 |
| CETN2 | centrin, EF-hand protein, 2 | 0.00439232 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.00439079 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00438791 |
| EMCN | endomucin | 0.00438301 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00437731 |
| PSMG1 | proteasome (prosome, macropain) assembly chaperone 1 | 0.00437727 |
| CPB1 | carboxypeptidase B1 (tissue) | 0.00436973 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.00435807 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00435173 |
| GPR65 | G protein-coupled receptor 65 | 0.00434749 |
| SLAMF7 | SLAM family member 7 | 0.00433878 |
| FAM111A | family with sequence similarity 111, member A | 0.00433112 |
| CLEC2D | C-type lectin domain family 2, member D | 0.00432599 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 | 0.00432583 |
| M6PR | mannose-6-phosphate receptor (cation dependent) | 0.00432573 |
| ATP6V1G1 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 | 0.00432451 |
| MELK | maternal embryonic leucine zipper kinase | 0.00431808 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.0043111 |
| ESM1 | endothelial cell-specific molecule 1 | 0.00430437 |
| BMP4 | bone morphogenetic protein 4 | 0.00429844 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00428295 |
| CD52 | CD52 molecule | 0.00427796 |
| TYMS | thymidylate synthetase | 0.00427642 |
| STOML2 | stomatin (EPB72)-like 2 | 0.00427482 |
| PSMF1 | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | 0.00426398 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | 0.00425983 |
| SIRT3 | sirtuin 3 | 0.00425855 |
| TRIB2 | tribbles pseudokinase 2 | 0.00425592 |
| MAGOHB | mago-nashi homolog B (Drosophila) | 0.00425512 |
| ERGIC2 | ERGIC and golgi 2 | 0.00422658 |
| TIE1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 0.00421185 |
| NXT2 | nuclear transport factor 2-like export factor 2 | 0.00419938 |
| MMP10 | matrix metallopeptidase 10 | 0.00418446 |
| ATF7IP | activating transcription factor 7 interacting protein | 0.0041799 |
| CNN3 | calponin 3, acidic | 0.00417786 |
| BEX4 | brain expressed, X-linked 4 | 0.00417574 |
| STOM | stomatin | 0.00416938 |
| CKM | creatine kinase, muscle | 0.00416903 |
| MB | myoglobin | 0.00416754 |
| KLHL41 | kelch-like family member 41 | 0.00416334 |
| ELP5 | elongator acetyltransferase complex subunit 5 | 0.004159 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.00415541 |
| CFI | complement factor I | 0.00414899 |
| PSMD12 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 0.00414432 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) | 0.00414299 |
| AK1 | adenylate kinase 1 | 0.00414289 |
| NOC3L | nucleolar complex associated 3 homolog (S. cerevisiae) | 0.00414152 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | 0.00413786 |
| RYR1 | ryanodine receptor 1 (skeletal) | 0.00413322 |
| CD59 | CD59 molecule, complement regulatory protein | 0.00412298 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.00412221 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.00411587 |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) | 0.00411507 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) | 0.00411077 |
| DMAC2L | distal membrane arm assembly component 2 like | 0.00409458 |
| RC3H2 | ring finger and CCCH-type domains 2 | 0.00409295 |
| NUCB2 | nucleobindin 2 | 0.00409173 |
| WT1 | Wilms tumor 1 | 0.00408802 |
| CLDN10 | claudin 10 | 0.00408512 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00408413 |
| SMC6 | structural maintenance of chromosomes 6 | 0.00406911 |
| ADA | adenosine deaminase | 0.00406499 |
| CDC42 | cell division cycle 42 | 0.00404342 |
| RFC4 | replication factor C (activator 1) 4, 37kDa | 0.00403446 |
| RECQL | RecQ helicase-like | 0.00402972 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | 0.00401032 |
| DGLUCY | D-glutamate cyclase | 0.00400913 |
| RACGAP1 | Rac GTPase activating protein 1 | 0.00400357 |
| NPY | neuropeptide Y | 0.00399985 |
| AGO3 | argonaute RISC catalytic component 3 | 0.00399954 |
| TIPIN | TIMELESS interacting protein | 0.00399618 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00398881 |
| MYBPC1 | myosin binding protein C, slow type | 0.0039861 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00398359 |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 | 0.00398129 |
| LMNB1 | lamin B1 | 0.00397913 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00397903 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.0039772 |
| MNDA | myeloid cell nuclear differentiation antigen | 0.00397699 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | 0.00397376 |
| RGS2 | regulator of G-protein signaling 2 | 0.00397357 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | 0.00397206 |
| SMPX | small muscle protein, X-linked | 0.00396852 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00396496 |
| EAF2 | ELL associated factor 2 | 0.00395241 |
| PPID | peptidylprolyl isomerase D | 0.00394474 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 0.0039413 |
| AREG | amphiregulin | 0.0039265 |
| EFCAB11 | EF-hand calcium binding domain 11 | 0.00392489 |
| MCTS1 | malignant T cell amplified sequence 1 | 0.00392429 |
| EXT1 | exostosin glycosyltransferase 1 | 0.00392332 |
| KRT7 | keratin 7, type II | 0.0039091 |
| ETNK1 | ethanolamine kinase 1 | 0.00389759 |
| NDC80 | NDC80 kinetochore complex component | 0.00389654 |
| MCM6 | minichromosome maintenance complex component 6 | 0.00389564 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GPX2 | glutathione peroxidase 2 | -0.0110113 |
| LEFTY1 | left-right determination factor 1 | -0.00909416 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.00874812 |
| FCGBP | Fc fragment of IgG binding protein | -0.00858316 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0084486 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00830965 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.00813783 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -0.00736755 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00733972 |
| AXIN1 | axin 1 | -0.00724284 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0072101 |
| WASHC4 | WASH complex subunit 4 | -0.00720642 |
| MUC4 | mucin 4, cell surface associated | -0.00701658 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00685921 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00683497 |
| APOD | apolipoprotein D | -0.00647689 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00637632 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00630524 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00625058 |
| H2AFV | H2A histone family, member V | -0.0062265 |
| CA12 | carbonic anhydrase XII | -0.00621259 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.00612258 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.00612095 |
| PERP | PERP, TP53 apoptosis effector | -0.00608003 |
| TSPAN8 | tetraspanin 8 | -0.00607624 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -0.00607486 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.00598698 |
| S100P | S100 calcium binding protein P | -0.00593894 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.00586694 |
| HOXC6 | homeobox C6 | -0.005851 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.00580323 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.00576683 |
| NOTCH2NL | notch 2 N-terminal like | -0.00568306 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.00567019 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | -0.00564358 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00562101 |
| IPO13 | importin 13 | -0.00560232 |
| GOLGA8A | golgin A8 family, member A | -0.00556563 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.00555739 |
| KRT20 | keratin 20, type I | -0.00555738 |
| MAOA | monoamine oxidase A | -0.0055565 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00555384 |
| CXADR | coxsackie virus and adenovirus receptor | -0.00554928 |
| SFN | stratifin | -0.0055429 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.00547567 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.00546868 |
| INAVA | innate immunity activator | -0.00541899 |
| GLDC | glycine dehydrogenase (decarboxylating) | -0.00539791 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00532302 |
| ANK2 | ankyrin 2, neuronal | -0.00532246 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | -0.00532096 |
| PIH1D1 | PIH1 domain containing 1 | -0.00532083 |
| EFNA5 | ephrin-A5 | -0.00531328 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00528861 |
| MPDZ | multiple PDZ domain protein | -0.00524481 |
| KLHDC8A | kelch domain containing 8A | -0.00519347 |
| HAL | histidine ammonia-lyase | -0.0051764 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.00515953 |
| DIO1 | deiodinase, iodothyronine, type I | -0.00515304 |
| CTSC | cathepsin C | -0.00514178 |
| VIL1 | villin 1 | -0.00509852 |
| SERINC5 | serine incorporator 5 | -0.005078 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 | -0.00505927 |
| CCL21 | chemokine (C-C motif) ligand 21 | -0.00504862 |
| XPO7 | exportin 7 | -0.00503816 |
| LRP4 | low density lipoprotein receptor-related protein 4 | -0.00498161 |
| MFSD10 | major facilitator superfamily domain containing 10 | -0.00496642 |
| OPN3 | opsin 3 | -0.00495999 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.00494542 |
| DKFZP586I1420 | uncharacterized protein DKFZp586I1420 | -0.00490408 |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 | -0.00484121 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.00482958 |
| CCNF | cyclin F | -0.004828 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.00480787 |
| MMP12 | matrix metallopeptidase 12 | -0.0047962 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | -0.00479537 |
| TOX3 | TOX high mobility group box family member 3 | -0.00477586 |
| MUC13 | mucin 13, cell surface associated | -0.00477225 |
| GDF15 | growth differentiation factor 15 | -0.00476035 |
| ATP5MG | ATP synthase membrane subunit g | -0.00474811 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 | -0.00473036 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.00471426 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00470721 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0046988 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.00469756 |
| TNC | tenascin C | -0.00467185 |
| LIPG | lipase, endothelial | -0.00465854 |
| BRD2 | bromodomain containing 2 | -0.00464075 |
| ARTN | artemin | -0.00463092 |
| THAP11 | THAP domain containing 11 | -0.00460438 |
| FABP1 | fatty acid binding protein 1, liver | -0.00459651 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.00459623 |
| GPA33 | glycoprotein A33 (transmembrane) | -0.00455828 |
| PRB1 | proline-rich protein BstNI subfamily 1 | -0.00454169 |
| H1-10 | H1.10 linker histone | -0.00453085 |
| IL32 | interleukin 32 | -0.00451797 |
| LAD1 | ladinin 1 | -0.00451708 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.00451622 |
| FBP1 | fructose-1,6-bisphosphatase 1 | -0.00451486 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.00451445 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | -0.00451347 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.00450342 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 | -0.00446931 |
| LONP2 | lon peptidase 2, peroxisomal | -0.00446721 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 | -0.00446529 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.00446267 |
| NDRG1 | N-myc downstream regulated 1 | -0.00445849 |
| BCHE | butyrylcholinesterase | -0.00444812 |
| HOXC10 | homeobox C10 | -0.00443241 |
| ATP10B | ATPase, class V, type 10B | -0.00442457 |
| NBEAL2 | neurobeachin-like 2 | -0.00441666 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.00438792 |
| PCDH9 | protocadherin 9 | -0.00437258 |
| STC1 | stanniocalcin 1 | -0.00436797 |
| HIPK1 | homeodomain interacting protein kinase 1 | -0.00433936 |
| MTARC1 | mitochondrial amidoxime reducing component 1 | -0.00433071 |
| FAM162A | family with sequence similarity 162, member A | -0.00431834 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 | -0.00431093 |
| CFH | complement factor H | -0.00430048 |
| YBX1 | Y box binding protein 1 | -0.00429313 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00429227 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | -0.00427795 |
| ITM2A | integral membrane protein 2A | -0.00427406 |
| GOLGA8H | golgin A8 family, member H | -0.00426923 |
| TSPO | translocator protein (18kDa) | -0.00424636 |
| FGB | fibrinogen beta chain | -0.00424591 |
| LPAR2 | lysophosphatidic acid receptor 2 | -0.00423979 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.00423962 |
| KRT2 | keratin 2, type II | -0.0042072 |
| TYMP | thymidine phosphorylase | -0.00419736 |
| PFKL | phosphofructokinase, liver | -0.00418592 |
| ZNF217 | zinc finger protein 217 | -0.00418267 |
| RNASET2 | ribonuclease T2 | -0.00417705 |
| SNX1 | sorting nexin 1 | -0.00417615 |
| HIP1R | huntingtin interacting protein 1 related | -0.00415115 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0041499 |
| TMEM43 | transmembrane protein 43 | -0.00414464 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.00414021 |
| S100A6 | S100 calcium binding protein A6 | -0.0041356 |
| GPM6A | glycoprotein M6A | -0.00412181 |
| RTN3 | reticulon 3 | -0.00412028 |
| TSC22D2 | TSC22 domain family, member 2 | -0.00409875 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | -0.00409557 |
| AZF1 | azoospermia factor 1 | -0.00409521 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | -0.00408534 |
| UPK1B | uroplakin 1B | -0.00408329 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | -0.00407757 |
| PKP1 | plakophilin 1 | -0.00407591 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.00407121 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.00405904 |
| MX2 | MX dynamin-like GTPase 2 | -0.0040507 |
| SPRR2B | small proline-rich protein 2B | -0.00404497 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.00404474 |
| ADAP1 | ArfGAP with dual PH domains 1 | -0.00404383 |
| STK38 | serine/threonine kinase 38 | -0.00404281 |
| SATB2 | SATB homeobox 2 | -0.0040377 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.00402967 |
| IL2RG | interleukin 2 receptor, gamma | -0.00402888 |
| ANKRD28 | ankyrin repeat domain 28 | -0.00401587 |
| FGFBP1 | fibroblast growth factor binding protein 1 | -0.00400556 |
| ZNF160 | zinc finger protein 160 | -0.00399836 |
| CAB39 | calcium binding protein 39 | -0.00399752 |
| EPHB3 | EPH receptor B3 | -0.00396659 |
| MX1 | MX dynamin-like GTPase 1 | -0.00396371 |
| HES1 | hes family bHLH transcription factor 1 | -0.00395249 |
| USP32P2 | ubiquitin specific peptidase 32 pseudogene 2 | -0.00394494 |
| CYTL1 | cytokine-like 1 | -0.0039353 |
| CALML3 | calmodulin-like 3 | -0.0039321 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00393048 |
| GALC | galactosylceramidase | -0.00392649 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.00392643 |
| CAPN15 | calpain 15 | -0.00392291 |
| KPNA6 | karyopherin alpha 6 (importin alpha 7) | -0.00392103 |
| FGA | fibrinogen alpha chain | -0.00391725 |
| NLGN4X | neuroligin 4, X-linked | -0.00390387 |
| RGS16 | regulator of G-protein signaling 16 | -0.00390285 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | -0.0038958 |
| CLTB | clathrin, light chain B | -0.00388692 |
| PRB4 | proline-rich protein BstNI subfamily 4 | -0.00388126 |
| CES1 | carboxylesterase 1 | -0.00385431 |
| EMP3 | epithelial membrane protein 3 | -0.00384272 |
| SALL2 | spalt-like transcription factor 2 | -0.00383981 |
| CLCA4 | chloride channel accessory 4 | -0.00383471 |
| ANTKMT | adenine nucleotide translocase lysine methyltransferase | -0.00383231 |
| SOX10 | SRY (sex determining region Y)-box 10 | -0.00383176 |
| ADCY1 | adenylate cyclase 1 (brain) | -0.00380821 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.00379256 |
| DMD | dystrophin | -0.00378838 |
| CPM | carboxypeptidase M | -0.00376729 |
| TG | thyroglobulin | -0.00376189 |
| SPRR1A | small proline-rich protein 1A | -0.00376137 |
| KLC2 | kinesin light chain 2 | -0.00375707 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 | -0.00375501 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | -0.00375322 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00375304 |
| CD99 | CD99 molecule | -0.00375265 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.00374875 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.00374556 |
| TESC | tescalcin | -0.00374328 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | -0.00373177 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.00371608 |
| GAP43 | growth associated protein 43 | -0.00371362 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.00370879 |
| DUOX2 | dual oxidase 2 | -0.00370349 |
| ASPH | aspartate beta-hydroxylase | -0.00370086 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | -0.00370028 |
| MGLL | monoglyceride lipase | -0.00369963 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.00369909 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.00369176 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00369072 |
| SNTB2 | syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) | -0.00367636 |
| SRSF6 | serine/arginine-rich splicing factor 6 | -0.00367548 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | -0.00367545 |
| NOX1 | NADPH oxidase 1 | -0.003675 |
| MZT2A | mitotic spindle organizing protein 2A | -0.00367348 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.00367206 |
| WFDC1 | WAP four-disulfide core domain 1 | -0.00367201 |
| KYNU | kynureninase | -0.00366451 |
| TFCP2L1 | transcription factor CP2-like 1 | -0.00366446 |
| PLA2G2D | phospholipase A2, group IID | -0.00366099 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | -0.00365966 |
| CD1B | CD1b molecule | -0.00364944 |
| PHF1 | PHD finger protein 1 | -0.00364764 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 | -0.00363885 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.00362381 |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 | -0.00361493 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.00361146 |
| HMGA1 | high mobility group AT-hook 1 | -0.00360036 |
| TMEM183A | transmembrane protein 183A | -0.00360028 |
| TRIM29 | tripartite motif containing 29 | -0.00359495 |
| CLCA1 | chloride channel accessory 1 | -0.00359438 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.00359272 |
| PRPF4B | pre-mRNA processing factor 4B | -0.00359169 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | -0.00359041 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.00358964 |
| ZC3H12A | zinc finger CCCH-type containing 12A | -0.00358857 |
| KRT13 | keratin 13, type I | -0.00358372 |
| PLS3 | plastin 3 | -0.00357916 |
| ADCY9 | adenylate cyclase 9 | -0.00357219 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.00357022 |
| NAV2 | neuron navigator 2 | -0.00356003 |
| RAP1GAP | RAP1 GTPase activating protein | -0.00355827 |
| OAZ1 | ornithine decarboxylase antizyme 1 | -0.00355349 |
| SPRR1B | small proline-rich protein 1B | -0.00354742 |
| DSG3 | desmoglein 3 | -0.00354738 |
| LAMB1 | laminin, beta 1 | -0.00354681 |
| ABHD14A | abhydrolase domain containing 14A | -0.00354348 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | -0.00354314 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00352955 |
| GAS1 | growth arrest-specific 1 | -0.00352225 |
